GWAS816853_H QTL Report (Homo sapiens) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
QTL Registration

QTL: GWAS816853_H (monocyte percentage of leukocytes QTL GWAS816853 (human)) Homo sapiens

Symbol: GWAS816853_H
Name: monocyte percentage of leukocytes QTL GWAS816853 (human)
RGD ID: 407167877
Trait: monocyte percentage of leukocytes
Measurement Type: blood monocyte count to total leukocyte count ratio   (CMO:0000374)    
LOD Score: Not Available
P Value: 6.0E-33
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38644,623,984 - 44,623,985RGD_MAPPER_PIPELINEGRCh38
GRCh37644,591,721 - 44,591,722RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS816853_HHumanblood monocyte count to total leukocyte count ratio  IAGPrs79894332405850206Based on the EFO term IDGWAS_CATALOGPMID:32888494

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS816853_HHumanmonocyte percentage of leukocytes  IAGPrs79894332405850206 GWAS_CATALOGPMID:32888494
Experimental Data Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Position Markers

Peak: (rs79894332)
Human AssemblyChrPosition (strand)Source
GRCh38644,623,984 - 44,623,985RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407167877GWAS816853_Hmonocyte percentage of leukocytes QTL GWAS816853 (human)6e-33monocyte percentage of leukocytesblood monocyte count to total leukocyte count ratio (CMO:0000374)64462398444623985Human
1358839MULTSCL5_HMultiple sclerosis susceptibility QTL 5 (human)Multiple sclerosis susceptibility61958431145584311Human
407240333GWAS889309_Hlymphocyte:monocyte ratio QTL GWAS889309 (human)4e-16lymphocyte:monocyte ratio64462398444623985Human
1358857MULTSCL19_HMultiple sclerosis susceptibility QTL 19 (human)Multiple sclerosis susceptibility61958431145584311Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS816853_H GCST90002394 Monocyte percentage of white cells 408,112 British individuals A 0.101243 6E-33 32.222 rs79894332 0.044037748 monocyte percentage of leukocytes (EFO:0007989)
 PMID:32888494
GWAS889309_H GCST90056181 Lymphocyte-to-monocyte ratio 234,184 European ancestry individuals G 0.898 4E-16 15.398 rs79894332 N/A lymphocyte:monocyte ratio (EFO:0600088)
 PMID:34469753
Database Acc Id Source(s)
GWAS Catalog GCST90002394 GWAS Catalog

RGD Curation Notes
Note Type Note Reference