GWAS799755_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS799755_H (very low density lipoprotein cholesterol measurement, esterified cholesterol measurement QTL GWAS799755 (human)) Homo sapiens

Symbol: GWAS799755_H
Name: very low density lipoprotein cholesterol measurement, esterified cholesterol measurement QTL GWAS799755 (human)
RGD ID: 407150779
Trait: very low density lipoprotein cholesterol measurement, esterified cholesterol measurement
Measurement Type: blood very low density lipoprotein cholesterol level   (CMO:0000648)    
LOD Score: Not Available
P Value: 3.0E-11
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3871,022,168 - 1,022,169RGD_MAPPER_PIPELINEGRCh38
GRCh3771,061,804 - 1,061,805RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS799755_HHumanblood very low density lipoprotein cholesterol level  IAGPrs12701499405850206Based on the EFO term IDGWAS_CATALOGPMID:38448586

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS799755_HHumanesterified cholesterol measurement  IAGPrs12701499405850206 GWAS_CATALOGPMID:38448586
GWAS799755_HHumanvery low density lipoprotein cholesterol measurement  IAGPrs12701499405850206 GWAS_CATALOGPMID:38448586
Experimental Data Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1603950CHLSNcholesin79779641138257Human

Position Markers

Peak: (rs12701499)
Human AssemblyChrPosition (strand)Source
GRCh3871,022,168 - 1,022,169RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407091091GWAS740067_Hcholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS740067 (human)5e-15cholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)710221681022169Human
1643402BMD2_HBone mineral density QTL 2 (human)2.690.0002Bone mineral density7122435431Human
407088903GWAS737879_Htriglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement QTL GWAS737879 (human)2e-11triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)710221681022169Human
407123441GWAS772417_Htriglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement QTL GWAS772417 (human)5e-25triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)710221681022169Human
1643247BW130_HBody Weight QTL 130 (human)1.280.008Body weightbody mass index7117453493Human
1643391BW322_HBody weight QTL 322 (human)2.690.0002Body fat amount7122435431Human
407091125GWAS740101_Hphospholipids:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS740101 (human)4e-11phospholipids:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)710221681022169Human
407157145GWAS806121_Hcholesterol in very small VLDL measurement QTL GWAS806121 (human)3e-12cholesterol in very small VLDL measurement 710221681022169Human
407150779GWAS799755_Hvery low density lipoprotein cholesterol measurement, esterified cholesterol measurement QTL GWAS799755 (human)3e-11very low density lipoprotein cholesterol measurement, esterified cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)710221681022169Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS737879_H GCST90302030 Triglycerides to total lipids ratio in large VLDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.2838 2E-11 10.699 rs12701499 0.0306 triglycerides:total lipids ratio (EFO:0020947)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:38448586
GWAS740067_H GCST90302034 Cholesteryl esters to total lipids ratio in medium HDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.2852 5E-15 14.302 rs12701499 0.0341 cholesteryl esters:total lipids ratio (EFO:0020944)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:38448586
GWAS740101_H GCST90302040 Phospholipids to total lipids ratio in medium HDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.2855 4E-11 10.398 rs12701499 0.029 phospholipids:total lipids ratio (EFO:0020946)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:38448586
GWAS772417_H GCST90302068 Triglycerides to total lipids ratio in medium VLDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.2846 5E-25 24.302 rs12701499 0.0447 triglycerides:total lipids ratio (EFO:0020947)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:38448586
GWAS799755_H GCST90302152 Cholesterol esters in very small VLDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.2858 3E-11 10.523 rs12701499 0.0295 very low density lipoprotein cholesterol measurement (EFO:0008317)
esterified cholesterol measurement (EFO:0008589)
 PMID:38448586
GWAS806121_H GCST90302150 Total cholesterol in very small VLDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.2858 3E-12 11.523 rs12701499 0.031 cholesterol in very small VLDL measurement (EFO:0022231)
 PMID:38448586
Database Acc Id Source(s)
GWAS Catalog GCST90302152 GWAS Catalog

RGD Curation Notes
Note Type Note Reference