GWAS793560_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS793560_H (BMI-adjusted waist-hip ratio, physical activity measurement QTL GWAS793560 (human)) Homo sapiens

Symbol: GWAS793560_H
Name: BMI-adjusted waist-hip ratio, physical activity measurement QTL GWAS793560 (human)
RGD ID: 407144584
Trait: BMI-adjusted waist-hip ratio, physical activity measurement
Measurement Type: voluntary body movement measurement   (CMO:0000954)    
LOD Score: Not Available
P Value: 4.0E-7
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38312,447,843 - 12,447,844RGD_MAPPER_PIPELINEGRCh38
GRCh37312,489,342 - 12,489,343RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS793560_HHumanvoluntary body movement measurement  IAGPrs17819328405850206Based on the EFO term IDGWAS_CATALOGPMID:28448500

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS793560_HHumanBMI-adjusted waist-hip ratio  IAGPrs17819328405850206 GWAS_CATALOGPMID:28448500
GWAS793560_HHumanphysical activity measurement  IAGPrs17819328405850206 GWAS_CATALOGPMID:28448500
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Position Markers

Peak: (rs17819328)
Human AssemblyChrPosition (strand)Source
GRCh38312,447,843 - 12,447,844RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
406949729GWAS598705_HBMI-adjusted waist-hip ratio QTL GWAS598705 (human)4e-14BMI-adjusted waist-hip ratio31244784312447844Human
407361253GWAS1010229_HBMI-adjusted hip circumference QTL GWAS1010229 (human)2e-35BMI-adjusted hip circumferencehip circumference (CMO:0000014)31244784312447844Human
407078592GWAS727568_Hwaist-hip ratio QTL GWAS727568 (human)5e-08waist-hip ratiowaist to hip ratio (WHR) (CMO:0000020)31244784312447844Human
406949730GWAS598706_HBMI-adjusted waist-hip ratio QTL GWAS598706 (human)6e-10BMI-adjusted waist-hip ratio31244784312447844Human
406963721GWAS612697_Hgut microbiome measurement QTL GWAS612697 (human)0.000005gut microbiome measurement31244784312447844Human
406893929GWAS542905_HBMI-adjusted waist-hip ratio QTL GWAS542905 (human)0.000009BMI-adjusted waist-hip ratio31244784312447844Human
407359342GWAS1008318_HBMI-adjusted hip circumference QTL GWAS1008318 (human)1e-29BMI-adjusted hip circumferencehip circumference (CMO:0000014)31244784312447844Human
407036264GWAS685240_Hwaist-hip ratio QTL GWAS685240 (human)2e-12waist-hip ratiowaist to hip ratio (WHR) (CMO:0000020)31244784312447844Human
406948938GWAS597914_HBMI-adjusted hip circumference QTL GWAS597914 (human)2e-10BMI-adjusted hip circumferencehip circumference (CMO:0000014)31244784312447844Human
407144584GWAS793560_HBMI-adjusted waist-hip ratio, physical activity measurement QTL GWAS793560 (human)0.0000004BMI-adjusted waist-hip ratiovoluntary body movement measurement (CMO:0000954)31244784312447844Human
406892493GWAS541469_HBMI-adjusted waist-hip ratio, physical activity measurement QTL GWAS541469 (human)0.0000006smoking behavior, BMI-adjusted waist-hip ratiovoluntary body movement measurement (CMO:0000954)31244784312447844Human
407144585GWAS793561_HBMI-adjusted waist-hip ratio, physical activity measurement QTL GWAS793561 (human)4e-08BMI-adjusted waist-hip ratio, physical activity measurementvoluntary body movement measurement (CMO:0000954)31244784312447844Human
406895503GWAS544479_Hsmoking behavior, BMI-adjusted waist-hip ratio QTL GWAS544479 (human)9e-10BMI-adjusted hip circumferencehip circumference (CMO:0000014)31244784312447844Human
406887923GWAS536899_HBMI-adjusted waist-hip ratio, physical activity measurement QTL GWAS536899 (human)0.000006BMI-adjusted waist-hip ratio, physical activity measurementvoluntary body movement measurement (CMO:0000954)31244784312447844Human
406893047GWAS542023_HBMI-adjusted waist-hip ratio, sex interaction measurement, age at assessment QTL GWAS542023 (human)9e-09BMI-adjusted waist-hip ratio, sex interaction measurement, age at assessment31244784312447844Human
406949689GWAS598665_HBMI-adjusted waist-hip ratio QTL GWAS598665 (human)5e-14BMI-adjusted waist-hip ratio31244784312447844Human
406894009GWAS542985_HBMI-adjusted waist-hip ratio QTL GWAS542985 (human)0.0000001BMI-adjusted waist-hip ratio31244784312447844Human
407079674GWAS728650_HBMI-adjusted waist-hip ratio QTL GWAS728650 (human)1e-38BMI-adjusted waist-hip ratio31244784312447844Human
2316345GLUCO224_HGlucose level QTL 224 (human)1.270.008Glucose level3121543441Human
406949690GWAS598666_HBMI-adjusted waist-hip ratio QTL GWAS598666 (human)2e-09BMI-adjusted waist-hip ratio31244784312447844Human
407156248GWAS805224_Htype 2 diabetes mellitus QTL GWAS805224 (human)5e-16type 2 diabetes mellitus31244784312447844Human
406894014GWAS542990_HBMI-adjusted waist-hip ratio QTL GWAS542990 (human)0.000002waist-hip ratiowaist to hip ratio (WHR) (CMO:0000020)31244784312447844Human
407163226GWAS812202_HBMI-adjusted waist-hip ratio QTL GWAS812202 (human)0.000007BMI-adjusted waist-hip ratio31244784312447844Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS536899_H GCST004567 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) 2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals ? 0.43179999999999996 0.000006 5.222 rs17819328 N/A BMI-adjusted waist-hip ratio (EFO:0007788)
physical activity measurement (EFO:0008002)
 PMID:28448500
GWAS541469_H GCST004567 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) 2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals ? 0.43179999999999996 6E-7 6.222 rs17819328 N/A BMI-adjusted waist-hip ratio (EFO:0007788)
physical activity measurement (EFO:0008002)
 PMID:28448500
GWAS542023_H GCST005962 Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) up to 43,776 European ancestry men aged <50, up to 50,526 European ancestry women aged <50, up to 69,944 European ancestry men aged >50, up to 88,129 European ancestry women aged >50 G 0.43114 9E-9 8.046 rs17819328 N/A BMI-adjusted waist-hip ratio (EFO:0007788)
sex interaction measurement (EFO:0008343)
age at assessment (EFO:0008007)
 PMID:26426971
GWAS542905_H GCST005957 Waist-to-hip ratio adjusted for BMI (age <50) up to 43,776 European ancestry men, up to 50,526 European ancestry women G 0.43 0.000009 5.046 rs17819328 0.035 BMI-adjusted waist-hip ratio (EFO:0007788)
 PMID:26426971
GWAS542985_H GCST005956 Waist-to-hip ratio adjusted for BMI up to 113,720 European ancestry men, up to 138,655 European ancestry women T 0.568866821787217 1E-7 7 rs17819328 0.018419184 BMI-adjusted waist-hip ratio (EFO:0007788)
 PMID:26426971
GWAS542990_H GCST005958 Waist-to-hip ratio adjusted for BMI (age >50) up to 69,944 European ancestry men, up to 88,129 European ancestry women G 0.43113999999999997 0.000002 5.699 rs17819328 0.0288 BMI-adjusted waist-hip ratio (EFO:0007788)
 PMID:26426971
None Available GCST004507 Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) 95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men T 0.5694 0.000006 5.222 rs17819328 N/A smoking behavior (EFO:0004318)
BMI-adjusted waist-hip ratio (EFO:0007788)
 PMID:28443625
None Available GCST005956 Waist-to-hip ratio adjusted for BMI up to 113,720 European ancestry men, up to 138,655 European ancestry women G 0.43114 1E-7 7 rs17819328 0.0288 BMI-adjusted waist-hip ratio (EFO:0007788)
 PMID:26426971
GWAS544479_H GCST004505 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) 95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men T 0.5694 9E-10 9.046 rs17819328 0.0294 smoking behavior (EFO:0004318)
BMI-adjusted waist-hip ratio (EFO:0007788)
 PMID:28443625
None Available GCST004505 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) 95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men T 0.5694 6E-7 6.222 rs17819328 0.0181 smoking behavior (EFO:0004318)
BMI-adjusted waist-hip ratio (EFO:0007788)
 PMID:28443625
None Available GCST004508 Waist-to-hip ratio adjusted for BMI in non-smokers 75,379 European ancestry women, 45,811 European ancestry men, 4,856 European ancestry individuals, 8,799 African American/Afro-Caribbean ancestry women, 1,803 African American/Afro-Caribbean ancestry men, 1,020 Indian Asian ancestry women, 6,691 Indian Asian ancestry men, 1,526 Filipino ancestry women, 2,469 Hispanic/Latino ancestry women, 1,318 Hispanic/Latino ancestry men T 0.5694 0.000002 5.699 rs17819328 0.0162 BMI-adjusted waist-hip ratio (EFO:0007788)
 PMID:28443625
GWAS597914_H GCST004067 Hip circumference adjusted for BMI up to 56,910 European ancestry men, up to 86,570 European ancestry women T 0.5686 2E-10 9.699 rs17819328 0.03 BMI-adjusted hip circumference (EFO:0008039)
 PMID:25673412
None Available GCST004067 Hip circumference adjusted for BMI up to 56,910 European ancestry men, up to 86,570 European ancestry women T 0.5686 9E-10 9.046 rs17819328 0.0227 BMI-adjusted hip circumference (EFO:0008039)
 PMID:25673412
GWAS598665_H GCST002782 Waist-to-hip ratio adjusted for body mass index up to 56,910 European ancestry men, up to 86,570 European ancestry women G 0.4318 5E-14 13.302 rs17819328 0.0352 BMI-adjusted waist-hip ratio (EFO:0007788)
 PMID:25673412
GWAS598666_H GCST002782 Waist-to-hip ratio adjusted for body mass index up to 56,910 European ancestry men, up to 86,570 European ancestry women G 0.4317 2E-9 8.699 rs17819328 0.0208 BMI-adjusted waist-hip ratio (EFO:0007788)
 PMID:25673412
GWAS598705_H GCST002782 Waist-to-hip ratio adjusted for body mass index up to 56,910 European ancestry men, up to 86,570 European ancestry women G 0.4277 4E-14 13.398 rs17819328 0.0348 BMI-adjusted waist-hip ratio (EFO:0007788)
 PMID:25673412
GWAS598706_H GCST002782 Waist-to-hip ratio adjusted for body mass index up to 56,910 European ancestry men, up to 86,570 European ancestry women G 0.4302 6E-10 9.222 rs17819328 0.0211 BMI-adjusted waist-hip ratio (EFO:0007788)
 PMID:25673412
GWAS612697_H GCST003854 Gut microbiota (functional units) 984 European ancestry individuals G NR 0.000005 5.302 rs17819328 4.565011 gut microbiome measurement (EFO:0007874)
 PMID:27694959
None Available GCST004064 Waist-hip ratio up to 56,910 European ancestry men, up to 86,570 European ancestry women T 0.568 0.000002 5.699 rs17819328 0.0163 waist-hip ratio (EFO:0004343)
 PMID:25673412
GWAS685240_H GCST004064 Waist-hip ratio up to 56,910 European ancestry men, up to 86,570 European ancestry women T 0.568 2E-12 11.699 rs17819328 0.0321 waist-hip ratio (EFO:0004343)
 PMID:25673412
GWAS727568_H GCST008734 Waist-hip ratio 663,598 European ancestry individuals G 0.43 5E-8 7.302 rs17819328 N/A waist-hip ratio (EFO:0004343)
 PMID:30575882
GWAS728650_H GCST008733 Waist-to-hip ratio adjusted for BMI 660,648 European ancestry individuals G 0.43 1E-38 38 rs17819328 0.023 BMI-adjusted waist-hip ratio (EFO:0007788)
 PMID:30575882
GWAS793560_H GCST004576 Waist-to-hip ratio adjusted for body mass index 2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals G 0.431799999999999 4E-7 6.398 rs17819328 0.0196 BMI-adjusted waist-hip ratio (EFO:0007788)
physical activity measurement (EFO:0008002)
 PMID:28448500
GWAS793561_H GCST004576 Waist-to-hip ratio adjusted for body mass index 2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals G 0.431799999999999 4E-8 7.398 rs17819328 0.0283 BMI-adjusted waist-hip ratio (EFO:0007788)
physical activity measurement (EFO:0008002)
 PMID:28448500
GWAS805224_H GCST009379 Type 2 diabetes 74,124 European ancestry cases, 824,006 European ancestry controls G 0.4249 5E-16 15.302 rs17819328 1.06 PMID:30297969
None Available GCST004578 Waist-to-hip ratio adjusted for BMI in active individuals 1,957 African American women, 1,421 Filipino ancestry women, 305 Indian ancestry women, 65,539 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 41,673 European ancestry men, 4,819 European ancestry individuals G 0.43200000000000005 4E-7 6.398 rs17819328 0.0307 BMI-adjusted waist-hip ratio (EFO:0007788)
 PMID:28448500
GWAS812202_H GCST004578 Waist-to-hip ratio adjusted for BMI in active individuals 1,957 African American women, 1,421 Filipino ancestry women, 305 Indian ancestry women, 65,539 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 41,673 European ancestry men, 4,819 European ancestry individuals G 0.43179999999999996 0.000007 5.155 rs17819328 0.021 BMI-adjusted waist-hip ratio (EFO:0007788)
 PMID:28448500
None Available GCST004578 Waist-to-hip ratio adjusted for BMI in active individuals 1,957 African American women, 1,421 Filipino ancestry women, 305 Indian ancestry women, 65,539 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 41,673 European ancestry men, 4,819 European ancestry individuals G 0.43200000000000005 4E-7 6.398 rs17819328 0.0307 BMI-adjusted waist-hip ratio (EFO:0007788)
 PMID:28448500
GWAS1008318_H GCST90020028 Hip circumference adjusted for BMI 219,872 British ancestry women G NR 1E-29 29 rs17819328 0.0322805 BMI-adjusted hip circumference (EFO:0008039)
 PMID:34021172
GWAS1010229_H GCST90020026 Hip index 219,872 British ancestry women G NR 2E-35 34.699 rs17819328 0.0368679 BMI-adjusted hip circumference (EFO:0008039)
 PMID:34021172
Database Acc Id Source(s)
GWAS Catalog GCST004576 GWAS Catalog
  GCST004578 GWAS Catalog

RGD Curation Notes
Note Type Note Reference