GWAS781333_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS781333_H (triglyceride:HDL cholesterol ratio QTL GWAS781333 (human)) Homo sapiens

Symbol: GWAS781333_H
Name: triglyceride:HDL cholesterol ratio QTL GWAS781333 (human)
RGD ID: 407132357
Trait: triglyceride:HDL cholesterol ratio
LOD Score: Not Available
P Value: 2.0E-16
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh386160,591,981 - 160,591,982RGD_MAPPER_PIPELINEGRCh38
GRCh376161,013,013 - 161,013,014RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS781333_HHumantriglyceride:HDL cholesterol ratio  IAGPrs140570886405850206 GWAS_CATALOGPMID:38200128
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1343679LPAlipoprotein(a)6160531482160664275Human

Position Markers

Peak: (rs140570886)
Human AssemblyChrPosition (strand)Source
GRCh386160,591,981 - 160,591,982RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407132357GWAS781333_Htriglyceride:HDL cholesterol ratio QTL GWAS781333 (human)2e-16triglyceride:HDL cholesterol ratio6160591981160591982Human
407182919GWAS831895_Hvery low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio QTL GWAS831895 (human)8e-32very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratioblood very low density lipoprotein cholesterol level (CMO:0000648)6160591981160591982Human
407296324GWAS945300_Hcholesteryl ester measurement, very low density lipoprotein cholesterol measurement QTL GWAS945300 (human)2e-33blood lipid amount (VT:0003949)blood very low density lipoprotein cholesterol level (CMO:0000648)6160591981160591982Human
406904523GWAS553499_Htriglyceride measurement QTL GWAS553499 (human)2e-42triglyceride measurementblood triglyceride level (CMO:0000118)6160591981160591982Human
407011917GWAS660893_HAgents acting on the renin-angiotensin system use measurement QTL GWAS660893 (human)4e-09Agents acting on the renin-angiotensin system use measurement6160591981160591982Human
407288777GWAS937753_Hvery low density lipoprotein cholesterol measurement, phospholipid measurement QTL GWAS937753 (human)9e-46very low density lipoprotein cholesterol measurement, phospholipid measurementblood very low density lipoprotein cholesterol level (CMO:0000648)6160591981160591982Human
407191637GWAS840613_Hmetabolic syndrome QTL GWAS840613 (human)5e-19metabolic syndrome6160591981160591982Human
1643404BMD3_HBone mineral density QTL 3 (human)2.420.0005Bone mineral density6157563614170805979Human
407252304GWAS901280_HAbdominal Aortic Aneurysm QTL GWAS901280 (human)1e-34Abdominal Aortic Aneurysm6160591981160591982Human
407189854GWAS838830_Hlow density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio QTL GWAS838830 (human)6e-28low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratioblood low density lipoprotein cholesterol level (CMO:0000053)6160591981160591982Human
407282653GWAS931629_Htriglyceride measurement, low density lipoprotein cholesterol measurement QTL GWAS931629 (human)1e-43triglyceride measurement, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)6160591981160591982Human
406994910GWAS643886_Hcoronary artery disease QTL GWAS643886 (human)2e-21coronary artery disease6160591981160591982Human
407327704GWAS976680_Htotal cholesterol measurement, very low density lipoprotein cholesterol measurement QTL GWAS976680 (human)6e-20total cholesterol measurement, very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)6160591981160591982Human
407327207GWAS976183_Hlow density lipoprotein cholesterol measurement QTL GWAS976183 (human)4e-32low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)6160591981160591982Human
407326436GWAS975412_Hcholesteryl ester measurement, low density lipoprotein cholesterol measurement QTL GWAS975412 (human)3e-32blood lipid amount (VT:0003949)blood low density lipoprotein cholesterol level (CMO:0000053)6160591981160591982Human
407291362GWAS940338_Hvery low density lipoprotein cholesterol measurement, phospholipid measurement QTL GWAS940338 (human)1e-82very low density lipoprotein cholesterol measurement, phospholipid measurementblood very low density lipoprotein cholesterol level (CMO:0000648)6160591981160591982Human
407185890GWAS834866_Hlow density lipoprotein cholesterol measurement, phospholipids:total lipids ratio QTL GWAS834866 (human)1e-21low density lipoprotein cholesterol measurement, phospholipids:total lipids ratioblood low density lipoprotein cholesterol level (CMO:0000053)6160591981160591982Human
407240162GWAS889138_Htriglyceride measurement, intermediate density lipoprotein measurement QTL GWAS889138 (human)7e-24triglyceride measurement, intermediate density lipoprotein measurementblood intermediate density lipoprotein cholesterol level (CMO:0001562)6160591981160591982Human
407329120GWAS978096_Hfatty acid measurement QTL GWAS978096 (human)2e-76fatty acid measurement6160591981160591982Human
407257326GWAS906302_Htotal cholesterol measurement, low density lipoprotein cholesterol measurement QTL GWAS906302 (human)6e-16total cholesterol measurement, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)6160591981160591982Human
407314030GWAS963006_Hpolyunsaturated fatty acid measurement QTL GWAS963006 (human)2e-44milk polyunsaturated fatty acid amount (VT:0010374)milk polyunsaturated fatty acid measurement (CMO:0000821)6160591981160591982Human
407329773GWAS978749_Hvery low density lipoprotein cholesterol measurement QTL GWAS978749 (human)3e-51very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)6160591981160591982Human
407323500GWAS972476_Htriglyceride measurement QTL GWAS972476 (human)1e-16triglyceride measurementblood triglyceride level (CMO:0000118)6160591981160591982Human
407293674GWAS942650_Hvery low density lipoprotein cholesterol measurement QTL GWAS942650 (human)2e-51very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)6160591981160591982Human
407255915GWAS904891_Hcholesteryl ester measurement, low density lipoprotein cholesterol measurement QTL GWAS904891 (human)7e-25blood lipid amount (VT:0003949)blood low density lipoprotein cholesterol level (CMO:0000053)6160591981160591982Human
407284587GWAS933563_Htriglyceride measurement, very low density lipoprotein cholesterol measurement QTL GWAS933563 (human)1e-96triglyceride measurement, very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)6160591981160591982Human
407314679GWAS963655_Hhigh density lipoprotein cholesterol measurement QTL GWAS963655 (human)2e-09high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)6160591981160591982Human
407333365GWAS982341_Htriglyceride measurement, very low density lipoprotein cholesterol measurement QTL GWAS982341 (human)2e-77triglyceride measurement, very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)6160591981160591982Human
407215603GWAS864579_Hlow density lipoprotein cholesterol measurement, lipid measurement QTL GWAS864579 (human)1e-08lipid measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)6160591981160591982Human
407309041GWAS958017_Hapolipoprotein B measurement QTL GWAS958017 (human)6e-17apolipoprotein B measurementblood apoliprotein B level (CMO:0000522)6160591981160591982Human
407315710GWAS964686_Hlow density lipoprotein cholesterol measurement, lipid measurement QTL GWAS964686 (human)8e-21low density lipoprotein cholesterol measurement, lipid measurementblood lipid measurement (CMO:0000050)6160591981160591982Human
407329533GWAS978509_Hlipoprotein measurement, phospholipid measurement QTL GWAS978509 (human)4e-23lipoprotein measurement, phospholipid measurementblood lipoprotein measurement (CMO:0002690)6160591981160591982Human
407288701GWAS937677_Hlow density lipoprotein cholesterol measurement, phospholipid measurement QTL GWAS937677 (human)4e-11low density lipoprotein cholesterol measurement, phospholipid measurementblood low density lipoprotein cholesterol level (CMO:0000053)6160591981160591982Human
407325692GWAS974668_Hlipid measurement, lipoprotein measurement QTL GWAS974668 (human)4e-41lipid measurement, lipoprotein measurementblood lipoprotein measurement (CMO:0002690)6160591981160591982Human
407331324GWAS980300_Hvery low density lipoprotein cholesterol measurement, phospholipid measurement QTL GWAS980300 (human)3e-13very low density lipoprotein cholesterol measurement, phospholipid measurementblood very low density lipoprotein cholesterol level (CMO:0000648)6160591981160591982Human
406918269GWAS567245_Htriglyceride measurement QTL GWAS567245 (human)3e-34triglyceride measurementblood triglyceride level (CMO:0000118)6160591981160591982Human
407182200GWAS831176_Hcholesteryl ester measurement, very low density lipoprotein cholesterol measurement QTL GWAS831176 (human)3e-61blood lipid amount (VT:0003949)blood very low density lipoprotein cholesterol level (CMO:0000648)6160591981160591982Human
407334279GWAS983255_Hvery low density lipoprotein cholesterol measurement, lipid measurement QTL GWAS983255 (human)2e-11very low density lipoprotein cholesterol measurement, lipid measurementblood lipid measurement (CMO:0000050)6160591981160591982Human
407312390GWAS961366_Hcholesteryl ester measurement, very low density lipoprotein cholesterol measurement QTL GWAS961366 (human)6e-76blood lipid amount (VT:0003949)blood very low density lipoprotein cholesterol level (CMO:0000648)6160591981160591982Human
407290498GWAS939474_Hfree cholesterol measurement, very low density lipoprotein cholesterol measurement QTL GWAS939474 (human)1e-73free cholesterol measurement, very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)6160591981160591982Human
407216515GWAS865491_Hlow density lipoprotein cholesterol measurement QTL GWAS865491 (human)1e-18free cholesterol measurement, very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)6160591981160591982Human
407332737GWAS981713_Htriglyceride measurement, very low density lipoprotein cholesterol measurement QTL GWAS981713 (human)7e-40triglyceride measurement, very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)6160591981160591982Human
407111310GWAS760286_Hcardiovascular disease QTL GWAS760286 (human)1e-23cardiovascular disease6160591981160591982Human
407312525GWAS961501_Hcholesteryl ester measurement, very low density lipoprotein cholesterol measurement QTL GWAS961501 (human)4e-20blood lipid amount (VT:0003949)blood very low density lipoprotein cholesterol level (CMO:0000648)6160591981160591982Human
407185422GWAS834398_Htotal cholesterol measurement, very low density lipoprotein cholesterol measurement QTL GWAS834398 (human)1e-78total cholesterol measurement, very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)6160591981160591982Human
407313036GWAS962012_Hserum non-albumin protein measurement QTL GWAS962012 (human)6e-11serum non-albumin protein measurementserum globulin level (CMO:0002399)6160591981160591982Human
407329416GWAS978392_Hvery low density lipoprotein cholesterol measurement QTL GWAS978392 (human)1e-49very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)6160591981160591982Human
407327895GWAS976871_Htotal cholesterol measurement, very low density lipoprotein cholesterol measurement QTL GWAS976871 (human)8e-100total cholesterol measurement, very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)6160591981160591982Human
407324950GWAS973926_Hvery low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio QTL GWAS973926 (human)3e-12very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratioblood very low density lipoprotein cholesterol level (CMO:0000648)6160591981160591982Human
407011601GWAS660577_HAntithrombotic agent use measurement QTL GWAS660577 (human)3e-18phospholipid measurement6160591981160591982Human
407014420GWAS663396_HHMG CoA reductase inhibitor use measurement QTL GWAS663396 (human)1e-41HMG CoA reductase inhibitor use measurement6160591981160591982Human
407187100GWAS836076_Htriglyceride measurement, low density lipoprotein cholesterol measurement QTL GWAS836076 (human)3e-25low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)6160591981160591982Human
407017496GWAS666472_Haspirin use measurement QTL GWAS666472 (human)2e-12phospholipid measurement6160591981160591982Human
407090713GWAS739689_Hcoronary artery disease QTL GWAS739689 (human)3e-87coronary artery disease6160591981160591982Human
407310107GWAS959083_Hlinoleic acid measurement QTL GWAS959083 (human)2e-47linoleic acid measurementblood free fatty acids level (CMO:0000117)6160591981160591982Human
407314456GWAS963432_Hfree cholesterol measurement QTL GWAS963432 (human)7e-16free cholesterol measurementblood cholesterol level (CMO:0002280)6160591981160591982Human
407292198GWAS941174_Hvery low density lipoprotein cholesterol measurement, lipid measurement QTL GWAS941174 (human)2e-105very low density lipoprotein cholesterol measurement, lipid measurementblood lipid measurement (CMO:0000050)6160591981160591982Human
407236135GWAS885111_Hcholine measurement QTL GWAS885111 (human)2e-14choline measurement6160591981160591982Human
407314724GWAS963700_Hvery low density lipoprotein cholesterol measurement, lipid measurement QTL GWAS963700 (human)3e-49very low density lipoprotein cholesterol measurement, lipid measurementblood lipid measurement (CMO:0000050)6160591981160591982Human
407326498GWAS975474_Hfatty acid measurement QTL GWAS975474 (human)1e-77fatty acid measurement6160591981160591982Human
407015973GWAS664949_HVasodilators used in cardiac diseases use measurement QTL GWAS664949 (human)2e-10apolipoprotein A 1 measurement, apolipoprotein B measurementblood apoliprotein B level (CMO:0000522)6160591981160591982Human
406990378GWAS639354_Hlipoprotein A measurement, apolipoprotein A 1 measurement QTL GWAS639354 (human)2e-210lipoprotein A measurement, apolipoprotein A 1 measurementblood apolipoprotein AI level (CMO:0000520)6160591981160591982Human
407288623GWAS937599_Hfree cholesterol measurement, very low density lipoprotein cholesterol measurement QTL GWAS937599 (human)1e-32free cholesterol measurement, very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)6160591981160591982Human
407291437GWAS940413_Htriglyceride measurement, high density lipoprotein cholesterol measurement QTL GWAS940413 (human)5e-45triglyceride measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)6160591981160591982Human
407182889GWAS831865_Hvery low density lipoprotein cholesterol measurement QTL GWAS831865 (human)7e-110very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)6160591981160591982Human
407333163GWAS982139_Hvery low density lipoprotein cholesterol measurement, phospholipid measurement QTL GWAS982139 (human)2e-32very low density lipoprotein cholesterol measurement, phospholipid measurementblood very low density lipoprotein cholesterol level (CMO:0000648)6160591981160591982Human
407183403GWAS832379_Hfree cholesterol measurement, very low density lipoprotein cholesterol measurement QTL GWAS832379 (human)9e-95free cholesterol measurement, very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)6160591981160591982Human
407242409GWAS891385_Hcholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement QTL GWAS891385 (human)2e-18total cholesterol measurement, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)6160591981160591982Human
407254569GWAS903545_Hlow density lipoprotein cholesterol measurement, lipid measurement QTL GWAS903545 (human)4e-17low density lipoprotein cholesterol measurement, lipid measurementblood lipid measurement (CMO:0000050)6160591981160591982Human
407291689GWAS940665_Hphospholipid measurement, high density lipoprotein cholesterol measurement QTL GWAS940665 (human)1e-09very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)6160591981160591982Human
407131956GWAS780932_Htriglyceride:HDL cholesterol ratio QTL GWAS780932 (human)7e-23triglyceride:HDL cholesterol ratio6160591981160591982Human
407288758GWAS937734_Hvery low density lipoprotein cholesterol measurement, lipid measurement QTL GWAS937734 (human)2e-63very low density lipoprotein cholesterol measurement, lipid measurementblood lipid measurement (CMO:0000050)6160591981160591982Human
406918452GWAS567428_Hheart failure QTL GWAS567428 (human)8e-11heart failure6160591981160591982Human
407027767GWAS676743_Haortic stenosis QTL GWAS676743 (human)2e-17aortic stenosis6160591981160591982Human
407260979GWAS909955_Htriglyceride measurement, low density lipoprotein cholesterol measurement QTL GWAS909955 (human)7e-64triglyceride measurement, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)6160591981160591982Human
407184563GWAS833539_Hvery low density lipoprotein cholesterol measurement, lipid measurement QTL GWAS833539 (human)2e-110very low density lipoprotein cholesterol measurement, lipid measurementblood lipid measurement (CMO:0000050)6160591981160591982Human
407285951GWAS934927_Hvery low density lipoprotein cholesterol measurement QTL GWAS934927 (human)6e-52very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)6160591981160591982Human
407182911GWAS831887_Hvery low density lipoprotein cholesterol measurement, phospholipid measurement QTL GWAS831887 (human)5e-99very low density lipoprotein cholesterol measurement, phospholipid measurementblood very low density lipoprotein cholesterol level (CMO:0000648)6160591981160591982Human
407256124GWAS905100_Homega-6 polyunsaturated fatty acid measurement QTL GWAS905100 (human)8e-42omega-6 polyunsaturated fatty acid measurement6160591981160591982Human
407015359GWAS664335_HBeta blocking agent use measurement QTL GWAS664335 (human)3e-09triglyceride:HDL cholesterol ratio6160591981160591982Human
1643367BW323_HBody weight QTL 323 (human)2.420.0005Body fat amount6157563614170805979Human
407257144GWAS906120_Hfatty acid measurement QTL GWAS906120 (human)4e-89fatty acid measurement6160591981160591982Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS553499_H GCST90244680 Triglyceride levels in non-type 2 diabetes 402,944 European ancestry individuals ? NR 2E-42 41.699 rs140570886 N/A triglyceride measurement (EFO:0004530)
 PMID:36269708
GWAS567245_H GCST010173 Triglyceride levels 324,694 British ancestry individuals ? NR 3E-34 33.523 rs140570886 0.131 triglyceride measurement (EFO:0004530)
 PMID:32154731
GWAS567428_H GCST009541 Heart failure 47,309 European ancestry cases, 930,014 European ancestry controls C 0.02 8E-11 10.097 rs140570886 1.24 heart failure (EFO:0003144)
 PMID:31919418
GWAS639354_H GCST004399 Lipoprotein(a) levels adjusted for apolipoprotein(a) isoforms 13,781 European ancestry individuals C NR 2E-210 209.699 rs140570886 43.43 lipoprotein A measurement (EFO:0006925)
apolipoprotein A 1 measurement (EFO:0004614)
 PMID:28512139
GWAS643886_H GCST007990 Coronary artery disease 4,831 European ancestry cases, 115,455 European ancestry controls C 0.02 2E-21 20.699 rs140570886 1.92 coronary artery disease (EFO:0001645)
 PMID:28714974
GWAS660577_H GCST007924 Medication use (antithrombotic agents) 67,653 European ancestry cases, 85,986 European ancestry controls C 0.0155987 3E-18 17.523 rs140570886 0.23748341 Antithrombotic agent use measurement (EFO:0009925)
 PMID:31015401
GWAS660893_H GCST007930 Medication use (agents acting on the renin-angiotensin system) 62,752 European ancestry cases, 174,778 European ancestry controls C 0.0148633 4E-9 8.398 rs140570886 0.14684165 Agents acting on the renin-angiotensin system use measurement (EFO:0009931)
 PMID:31015401
GWAS663396_H GCST007931 Medication use (HMG CoA reductase inhibitors) 73,475 European ancestry cases, 216,910 European ancestry controls C 0.0154611 1E-41 41 rs140570886 0.30737686 HMG CoA reductase inhibitor use measurement (EFO:0009932)
 PMID:31015401
GWAS664335_H GCST007927 Medication use (beta blocking agents) 31,700 European ancestry cases, 192,324 European ancestry controls C 0.0153689 3E-9 8.523 rs140570886 0.19912294 Beta blocking agent use measurement (EFO:0009929)
 PMID:31015401
GWAS664949_H GCST007925 Medication use (vasodilators used in cardiac diseases) 5,546 European ancestry cases, 237,113 European ancestry controls C 0.0155529 2E-10 9.699 rs140570886 0.49516246 Vasodilators used in cardiac diseases use measurement (EFO:0009926)
 PMID:31015401
GWAS666472_H GCST007937 Medication use (salicylic acid and derivatives) 61,583 European ancestry cases, 50,427 European ancestry controls C 0.0159652 2E-12 11.699 rs140570886 0.2234316 aspirin use measurement (EFO:0007013)
 PMID:31015401
GWAS676743_H GCST90276156 Aortic stenosis 13,765 European ancestry cases, 640,102 European ancestry controls ? NR 2E-17 16.699 rs140570886 1.48 aortic stenosis (EFO:0000266)
 PMID:37038246
GWAS739689_H GCST005194 Coronary artery disease 34,541 cases, 261,984 controls T 0.983 3E-87 86.523 rs140570886 0.481 coronary artery disease (EFO:0001645)
 PMID:29212778
GWAS760286_H GCST007072 Cardiovascular disease approximately 459,000 European ancestry individuals ? NR 1E-23 23 rs140570886 N/A cardiovascular disease (EFO:0000319)
 PMID:30595370
GWAS780932_H GCST90295949 Triglyceride to HDL cholesterol ratio 402,398 European ancestry individuals T 0.9845 7E-23 22.155 rs140570886 0.1272 triglyceride:HDL cholesterol ratio (EFO:0007929)
 PMID:38200128
None Available GCST90295950 Triglyceride to HDL cholesterol ratio 185,749 European ancestry individuals T 0.9844 3E-9 8.523 rs140570886 0.0926 triglyceride:HDL cholesterol ratio (EFO:0007929)
 PMID:38200128
GWAS781333_H GCST90295951 Triglyceride to HDL cholesterol ratio 216,649 European ancestry individuals T 0.9845 2E-16 15.699 rs140570886 0.1231 triglyceride:HDL cholesterol ratio (EFO:0007929)
 PMID:38200128
GWAS831176_H GCST90092870 Cholesteryl ester levels in large VLDL 115,082 European ancestry individuals T 0.984514 3E-61 60.523 rs140570886 0.276728 cholesteryl ester measurement (EFO:0010351)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
GWAS831865_H GCST90092875 Concentration of large VLDL particles 115,082 European ancestry individuals T 0.984514 7E-110 109.155 rs140570886 0.36418 very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
GWAS831887_H GCST90092876 Phospholipid levels in large VLDL 115,082 European ancestry individuals T 0.984514 5E-99 98.302 rs140570886 0.345393 very low density lipoprotein cholesterol measurement (EFO:0008317)
phospholipid measurement (EFO:0004639)
 PMID:35213538
GWAS831895_H GCST90092877 Phospholipids to total lipids ratio in large VLDL 115,071 European ancestry individuals T 0.984517 8E-32 31.097 rs140570886 0.19345 very low density lipoprotein cholesterol measurement (EFO:0008317)
phospholipids:total lipids ratio (EFO:0020946)
 PMID:35213538
GWAS832379_H GCST90092872 Free cholesterol levels in large VLDL 115,082 European ancestry individuals T 0.984514 9E-95 94.046 rs140570886 0.338454 free cholesterol measurement (EFO:0008591)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
GWAS833539_H GCST90092874 Total lipid levels in large VLDL 115,082 European ancestry individuals T 0.984514 2E-110 109.699 rs140570886 0.365599 very low density lipoprotein cholesterol measurement (EFO:0008317)
lipid measurement (EFO:0004529)
 PMID:35213538
GWAS834398_H GCST90092868 Cholesterol levels in large VLDL 115,082 European ancestry individuals T 0.984514 1E-78 78 rs140570886 0.311148 total cholesterol measurement (EFO:0004574)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
GWAS834866_H GCST90092865 Phospholipids to total lipids ratio in large LDL 115,082 European ancestry individuals T 0.984514 1E-21 21 rs140570886 0.162224 low density lipoprotein cholesterol measurement (EFO:0004611)
phospholipids:total lipids ratio (EFO:0020946)
 PMID:35213538
GWAS836076_H GCST90092866 Triglyceride levels in large LDL 115,082 European ancestry individuals T 0.984514 3E-25 24.523 rs140570886 0.172442 triglyceride measurement (EFO:0004530)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
GWAS838830_H GCST90092859 Cholesteryl esters to total lipids ratio in large LDL 115,082 European ancestry individuals T 0.984514 6E-28 27.222 rs140570886 0.186529 low density lipoprotein cholesterol measurement (EFO:0004611)
cholesteryl esters:total lipids ratio (EFO:0020944)
 PMID:35213538
GWAS840613_H GCST90086077 Dyslipidemia 30,244 European ancestry cases, 26,393 European ancestry controls C 0.014 5E-19 18.302 rs140570886 1.66 metabolic syndrome (EFO:0000195)
 PMID:33893285
GWAS864579_H GCST90092886 Total lipid levels in LDL 115,082 European ancestry individuals T 0.984514 1E-8 8 rs140570886 0.0959864 low density lipoprotein cholesterol measurement (EFO:0004611)
lipid measurement (EFO:0004529)
 PMID:35213538
GWAS865491_H GCST90092887 Concentration of LDL particles 115,082 European ancestry individuals T 0.984514 1E-18 18 rs140570886 0.149359 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
GWAS885111_H GCST90092812 Total cholines levels 115,006 European ancestry individuals T 0.984503 2E-14 13.699 rs140570886 0.122482 choline measurement (EFO:0010116)
 PMID:35213538
None Available GCST90092810 Ratio of apolipoprotein B to apolipoprotein A1 levels 115,082 European ancestry individuals T 0.984514 2E-10 9.699 rs140570886 0.106013 apolipoprotein A 1 measurement (EFO:0004614)
apolipoprotein B measurement (EFO:0004615)
 PMID:35213538
GWAS889138_H GCST90092841 Triglyceride levels in IDL 115,082 European ancestry individuals T 0.984514 7E-24 23.155 rs140570886 0.167114 triglyceride measurement (EFO:0004530)
intermediate density lipoprotein measurement (EFO:0008595)
 PMID:35213538
GWAS891385_H GCST90092834 Cholesteryl esters to total lipids ratio in IDL 115,082 European ancestry individuals T 0.984514 2E-18 17.699 rs140570886 0.145389 cholesteryl esters:total lipids ratio (EFO:0020944)
intermediate density lipoprotein measurement (EFO:0008595)
 PMID:35213538
GWAS901280_H GCST90432152 Abdominal aortic aneurysm 37,214 European ancestry cases, 997,776 European ancestry controls, 2,007 African ancestry cases, 88,331 African ancestry controls ? NR 1E-34 34 rs140570886 0.3988 Abdominal Aortic Aneurysm (EFO:0004214)
 PMID:37845353
GWAS903545_H GCST90092910 Total lipid levels in medium LDL 115,082 European ancestry individuals T 0.984514 4E-17 16.398 rs140570886 0.143112 low density lipoprotein cholesterol measurement (EFO:0004611)
lipid measurement (EFO:0004529)
 PMID:35213538
None Available GCST90092931 Omega-3 fatty acid levels 115,006 European ancestry individuals T 0.984503 3E-18 17.523 rs140570886 0.142069 omega-3 polyunsaturated fatty acid measurement (EFO:0010119)
 PMID:35213538
GWAS904891_H GCST90092906 Cholesteryl ester levels in medium LDL 115,082 European ancestry individuals T 0.984514 7E-25 24.155 rs140570886 0.175081 cholesteryl ester measurement (EFO:0010351)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
GWAS905100_H GCST90092933 Omega-6 fatty acid levels 115,006 European ancestry individuals T 0.984503 8E-42 41.097 rs140570886 0.224634 omega-6 polyunsaturated fatty acid measurement (EFO:0005680)
 PMID:35213538
GWAS906120_H GCST90092928 Monounsaturated fatty acid levels 115,006 European ancestry individuals T 0.984503 4E-89 88.398 rs140570886 0.334628 fatty acid measurement (EFO:0005110)
 PMID:35213538
GWAS906302_H GCST90092904 Cholesterol levels in medium LDL 115,082 European ancestry individuals T 0.984514 6E-16 15.222 rs140570886 0.137847 total cholesterol measurement (EFO:0004574)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
GWAS909955_H GCST90092914 Triglyceride levels in medium LDL 115,082 European ancestry individuals T 0.984514 7E-64 63.155 rs140570886 0.279594 triglyceride measurement (EFO:0004530)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
GWAS931629_H GCST90092890 Triglyceride levels in LDL 115,082 European ancestry individuals T 0.984514 1E-43 43 rs140570886 0.230292 triglyceride measurement (EFO:0004530)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
GWAS933563_H GCST90092926 Triglyceride levels in medium VLDL 115,082 European ancestry individuals T 0.984514 1E-96 96 rs140570886 0.343342 triglyceride measurement (EFO:0004530)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
GWAS934927_H GCST90092923 Concentration of medium VLDL particles 115,082 European ancestry individuals T 0.984514 6E-52 51.222 rs140570886 0.256707 very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
None Available GCST90092911 Concentration of medium LDL particles 115,082 European ancestry individuals T 0.984514 3E-25 24.523 rs140570886 0.176612 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
None Available GCST90092937 Phosphatidylcholine levels 115,006 European ancestry individuals T 0.984503 2E-12 11.699 rs140570886 0.11202 phospholipid measurement (EFO:0004639)
 PMID:35213538
GWAS937599_H GCST90092920 Free cholesterol levels in medium VLDL 115,082 European ancestry individuals T 0.984514 1E-32 32 rs140570886 0.202078 free cholesterol measurement (EFO:0008591)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
GWAS937677_H GCST90092912 Phospholipid levels in medium LDL 115,082 European ancestry individuals T 0.984514 4E-11 10.398 rs140570886 0.11245 low density lipoprotein cholesterol measurement (EFO:0004611)
phospholipid measurement (EFO:0004639)
 PMID:35213538
GWAS937734_H GCST90092922 Total lipid levels in medium VLDL 115,082 European ancestry individuals T 0.984514 2E-63 62.699 rs140570886 0.283011 very low density lipoprotein cholesterol measurement (EFO:0008317)
lipid measurement (EFO:0004529)
 PMID:35213538
GWAS937753_H GCST90092924 Phospholipid levels in medium VLDL 115,082 European ancestry individuals T 0.984514 9E-46 45.046 rs140570886 0.240559 very low density lipoprotein cholesterol measurement (EFO:0008317)
phospholipid measurement (EFO:0004639)
 PMID:35213538
None Available GCST90092938 Phosphoglycerides levels 115,006 European ancestry individuals T 0.984503 3E-18 17.523 rs140570886 0.139681 phospholipid measurement (EFO:0004639)
 PMID:35213538
GWAS939474_H GCST90092998 Free cholesterol levels in VLDL 115,082 European ancestry individuals T 0.984514 1E-73 73 rs140570886 0.305256 free cholesterol measurement (EFO:0008591)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
GWAS940338_H GCST90093001 Phospholipid levels in VLDL 115,082 European ancestry individuals T 0.984514 1E-82 82 rs140570886 0.322319 very low density lipoprotein cholesterol measurement (EFO:0008317)
phospholipid measurement (EFO:0004639)
 PMID:35213538
GWAS940413_H GCST90092954 Triglyceride levels in small HDL 115,082 European ancestry individuals T 0.984514 5E-45 44.302 rs140570886 0.230749 triglyceride measurement (EFO:0004530)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS940665_H GCST90092952 Phospholipid levels in small HDL 115,082 European ancestry individuals T 0.984514 1E-9 9 rs140570886 0.101877 phospholipid measurement (EFO:0004639)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS941174_H GCST90092999 Total lipid levels in VLDL 115,082 European ancestry individuals T 0.984514 2E-105 104.699 rs140570886 0.361954 very low density lipoprotein cholesterol measurement (EFO:0008317)
lipid measurement (EFO:0004529)
 PMID:35213538
GWAS942650_H GCST90093000 Concentration of VLDL particles 115,082 European ancestry individuals T 0.984514 2E-51 50.699 rs140570886 0.253981 very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
GWAS945300_H GCST90092997 Cholesteryl ester levels in VLDL 115,082 European ancestry individuals T 0.984514 2E-33 32.699 rs140570886 0.204743 cholesteryl ester measurement (EFO:0010351)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
GWAS958017_H GCST90092809 Apolipoprotein B levels 115,082 European ancestry individuals T 0.984514 6E-17 16.222 rs140570886 0.141754 apolipoprotein B measurement (EFO:0004615)
 PMID:35213538
GWAS959083_H GCST90092880 Linoleic acid levels 115,006 European ancestry individuals T 0.984503 2E-47 46.699 rs140570886 0.241198 linoleic acid measurement (EFO:0006807)
 PMID:35213538
None Available GCST90092972 Free cholesterol levels in small VLDL 115,082 European ancestry individuals T 0.984514 1E-18 18 rs140570886 0.150084 free cholesterol measurement (EFO:0008591)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
GWAS961366_H GCST90093018 Cholesteryl ester levels in very large VLDL 115,082 European ancestry individuals T 0.984514 6E-76 75.222 rs140570886 0.307962 cholesteryl ester measurement (EFO:0010351)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
GWAS961501_H GCST90092970 Cholesteryl ester levels in small VLDL 115,082 European ancestry individuals T 0.984514 4E-20 19.398 rs140570886 0.155411 cholesteryl ester measurement (EFO:0010351)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
GWAS962012_H GCST90019515 Non-albumin protein levels 313,032 European ancestry individuals, 5,573 African ancestry individuals, 6,687 South Asian ancestry individuals C NR 6E-11 10.222 rs140570886 0.0679 serum non-albumin protein measurement (EFO:0004568)
 PMID:33462484
GWAS963006_H GCST90092939 Polyunsaturated fatty acid levels 115,006 European ancestry individuals T 0.984503 2E-44 43.699 rs140570886 0.2308 polyunsaturated fatty acid measurement (EFO:0010733)
 PMID:35213538
GWAS963432_H GCST90092988 Total free cholesterol levels 115,082 European ancestry individuals T 0.984514 7E-16 15.155 rs140570886 0.133922 free cholesterol measurement (EFO:0008591)
 PMID:35213538
GWAS963655_H GCST90179147 High-density lipoprotein levels (MTAG) 361,194 European ancestry individuals T NR 2E-9 8.699 rs140570886 0.0634 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:36376304
GWAS963700_H GCST90092974 Total lipid levels in small VLDL 115,082 European ancestry individuals T 0.984514 3E-49 48.523 rs140570886 0.24716 very low density lipoprotein cholesterol measurement (EFO:0008317)
lipid measurement (EFO:0004529)
 PMID:35213538
None Available GCST90092956 Cholesterol levels in small LDL 115,082 European ancestry individuals T 0.984514 2E-18 17.699 rs140570886 0.149502 total cholesterol measurement (EFO:0004574)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
GWAS964686_H GCST90092962 Total lipid levels in small LDL 115,082 European ancestry individuals T 0.984514 8E-21 20.097 rs140570886 0.158915 low density lipoprotein cholesterol measurement (EFO:0004611)
lipid measurement (EFO:0004529)
 PMID:35213538
None Available GCST90092950 Total lipid levels in small HDL 115,082 European ancestry individuals T 0.984514 1E-8 8 rs140570886 0.0970752 lipid measurement (EFO:0004529)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS972476_H GCST90179149 Triglyceride levels (MTAG) 361,194 European ancestry individuals T NR 1E-16 16 rs140570886 0.082686 triglyceride measurement (EFO:0004530)
 PMID:36376304
GWAS973926_H GCST90093025 Phospholipids to total lipids ratio in very large VLDL 114,160 European ancestry individuals T 0.984672 3E-12 11.523 rs140570886 0.119707 very low density lipoprotein cholesterol measurement (EFO:0008317)
phospholipids:total lipids ratio (EFO:0020946)
 PMID:35213538
GWAS974668_H GCST90092989 Total lipid levels in lipoprotein particles 115,082 European ancestry individuals T 0.984514 4E-41 40.398 rs140570886 0.224284 lipid measurement (EFO:0004529)
lipoprotein measurement (EFO:0004732)
 PMID:35213538
GWAS975412_H GCST90092958 Cholesteryl ester levels in small LDL 115,082 European ancestry individuals T 0.984514 3E-32 31.523 rs140570886 0.200744 cholesteryl ester measurement (EFO:0010351)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
GWAS975474_H GCST90092987 Total fatty acid levels 115,006 European ancestry individuals T 0.984503 1E-77 77 rs140570886 0.312199 fatty acid measurement (EFO:0005110)
 PMID:35213538
GWAS976183_H GCST90092963 Concentration of small LDL particles 115,082 European ancestry individuals T 0.984514 4E-32 31.398 rs140570886 0.200518 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
GWAS976680_H GCST90092968 Cholesterol levels in small VLDL 115,082 European ancestry individuals T 0.984514 6E-20 19.222 rs140570886 0.154996 total cholesterol measurement (EFO:0004574)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
GWAS976871_H GCST90093016 Cholesterol levels in very large VLDL 115,082 European ancestry individuals T 0.984514 8E-100 99.097 rs140570886 0.351188 total cholesterol measurement (EFO:0004574)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
GWAS978096_H GCST90092980 Saturated fatty acid levels 115,006 European ancestry individuals T 0.984503 2E-76 75.699 rs140570886 0.309662 fatty acid measurement (EFO:0005110)
 PMID:35213538
GWAS978392_H GCST90092996 VLDL cholesterol levels 115,082 European ancestry individuals T 0.984514 1E-49 49 rs140570886 0.250826 very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
GWAS978509_H GCST90092991 Total phospholipid levels in lipoprotein particles 115,082 European ancestry individuals T 0.984514 4E-23 22.398 rs140570886 0.15999 lipoprotein measurement (EFO:0004732)
phospholipid measurement (EFO:0004639)
 PMID:35213538
GWAS978749_H GCST90092975 Concentration of small VLDL particles 115,082 European ancestry individuals T 0.984514 3E-51 50.523 rs140570886 0.251367 very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
GWAS980300_H GCST90093036 Phospholipid levels in very small VLDL 115,082 European ancestry individuals T 0.984514 3E-13 12.523 rs140570886 0.121545 very low density lipoprotein cholesterol measurement (EFO:0008317)
phospholipid measurement (EFO:0004639)
 PMID:35213538
GWAS981713_H GCST90093038 Triglyceride levels in very small VLDL 115,082 European ancestry individuals T 0.984514 7E-40 39.155 rs140570886 0.218483 triglyceride measurement (EFO:0004530)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
GWAS982139_H GCST90092976 Phospholipid levels in small VLDL 115,082 European ancestry individuals T 0.984514 2E-32 31.699 rs140570886 0.200553 very low density lipoprotein cholesterol measurement (EFO:0008317)
phospholipid measurement (EFO:0004639)
 PMID:35213538
GWAS982341_H GCST90092978 Triglyceride levels in small VLDL 115,082 European ancestry individuals T 0.984514 2E-77 76.699 rs140570886 0.305108 triglyceride measurement (EFO:0004530)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
None Available GCST90093035 Concentration of very small VLDL particles 115,082 European ancestry individuals T 0.984514 1E-9 9 rs140570886 0.101428 very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
GWAS983255_H GCST90093034 Total lipid levels in very small VLDL 115,082 European ancestry individuals T 0.984514 2E-11 10.699 rs140570886 0.111392 very low density lipoprotein cholesterol measurement (EFO:0008317)
lipid measurement (EFO:0004529)
 PMID:35213538
None Available GCST90446533 Angina 25,257 European ancestry cases, 433,881 European ancestry controls ? NR 3E-39 38.523 rs140570886 N/A angina pectoris (EFO:0003913)
 PMID:37947095
None Available GCST90446535 Cardiovascular disease 44,238 European ancestry cases, 414,900 European ancestry controls ? NR 1E-47 47 rs140570886 N/A cardiovascular disease (EFO:0000319)
 PMID:37947095
None Available GCST90446534 Coronary heart disease 38,687 European ancestry cases, 420,451 European ancestry controls ? NR 5E-49 48.302 rs140570886 N/A coronary artery disease (EFO:0001645)
 PMID:37947095
None Available GCST90446532 Myocardial infarction 16,602 European ancestry cases, 442,536 European ancestry controls ? NR 9E-33 32.046 rs140570886 N/A myocardial infarction (EFO:0000612)
 PMID:37947095
Database Acc Id Source(s)
GWAS Catalog GCST90295951 GWAS Catalog

RGD Curation Notes
Note Type Note Reference