GWAS779458_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS779458_H (eosinophil percentage of leukocytes QTL GWAS779458 (human)) Homo sapiens

Symbol: GWAS779458_H
Name: eosinophil percentage of leukocytes QTL GWAS779458 (human)
RGD ID: 407130482
Trait: eosinophil percentage of leukocytes
Measurement Type: blood eosinophil count to total leukocyte count ratio   (CMO:0000369)    
LOD Score: Not Available
P Value: 2.0E-13
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh382133,060,745 - 33,060,746RGD_MAPPER_PIPELINEGRCh38
GRCh372134,433,051 - 34,433,052RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS779458_HHumanblood eosinophil count to total leukocyte count ratio  IAGPrs1000005405850206Based on the EFO term IDGWAS_CATALOGPMID:27863252

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS779458_HHumaneosinophil percentage of leukocytes  IAGPrs1000005405850206 GWAS_CATALOGPMID:27863252
Experimental Data Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
7250164LINC00945long intergenic non-protein coding RNA 945213305782933065079Human

Position Markers

Peak: (rs1000005)
Human AssemblyChrPosition (strand)Source
GRCh382133,060,745 - 33,060,746RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407296534GWAS945510_Heosinophil count QTL GWAS945510 (human)2e-09eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)213306074533060746Human
407130482GWAS779458_Heosinophil percentage of leukocytes QTL GWAS779458 (human)2e-13eosinophil percentage of leukocytesblood eosinophil count to total leukocyte count ratio (CMO:0000369)213306074533060746Human
407271777GWAS920753_Halcohol consumption measurement QTL GWAS920753 (human)3e-08alcohol consumption measurementethanol drink intake rate (CMO:0001407)213306074533060746Human
2303081MAMTS49_HMammary tumor susceptibility QTL 49 (human)1.72Mammary tumor susceptibility211795044843950448Human
407033918GWAS682894_Halcohol consumption measurement QTL GWAS682894 (human)5e-17alcohol consumption measurementethanol drink intake rate (CMO:0001407)213306074533060746Human
407128714GWAS777690_Heosinophil count QTL GWAS777690 (human)7e-12eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)213306074533060746Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS682894_H GCST90243989 Drinks per week 2,965,643 European ancestry, East Asian ancestry, Hispanic or Latin American, African ancestry individuals C 0.591 5E-17 16.302 rs1000005 0.0071 alcohol consumption measurement (EFO:0007878)
 PMID:36477530
GWAS777690_H GCST004606 Eosinophil counts 172,275 European ancestry individuals C 0.5894 7E-12 11.155 rs1000005 0.02481715 eosinophil count (EFO:0004842)
 PMID:27863252
GWAS779458_H GCST004600 Eosinophil percentage of white cells 172,378 European ancestry individuals C 0.5894 2E-13 12.699 rs1000005 0.02652552 eosinophil percentage of leukocytes (EFO:0007991)
 PMID:27863252
GWAS920753_H GCST010543 Alcohol consumption (drinks per week) (MTAG) 972,915 European ancestry individuals C 0.588 3E-8 7.523 rs1000005 0.009815596 alcohol consumption measurement (EFO:0007878)
 PMID:32451486
GWAS945510_H GCST90134621 Eosinophil counts 365,954 British ancestry individuals G 0.414 2E-9 8.699 rs1000005 0.022 eosinophil count (EFO:0004842)
 PMID:35935937
Database Acc Id Source(s)
GWAS Catalog GCST004600 GWAS Catalog

RGD Curation Notes
Note Type Note Reference