GWAS779392_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS779392_H (esterified cholesterol measurement, high density lipoprotein cholesterol measurement QTL GWAS779392 (human)) Homo sapiens

Symbol: GWAS779392_H
Name: esterified cholesterol measurement, high density lipoprotein cholesterol measurement QTL GWAS779392 (human)
RGD ID: 407130416
Trait: esterified cholesterol measurement, high density lipoprotein cholesterol measurement
Measurement Type: blood high density lipoprotein cholesterol level   (CMO:0000052)    
LOD Score: Not Available
P Value: 6.0E-13
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3876,379,702 - 6,379,703RGD_MAPPER_PIPELINEGRCh38
GRCh3776,419,333 - 6,419,334RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS779392_HHumanblood high density lipoprotein cholesterol level  IAGPrs861369405850206Based on the EFO term IDGWAS_CATALOGPMID:38448586

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS779392_HHumanesterified cholesterol measurement  IAGPrs861369405850206 GWAS_CATALOGPMID:38448586
GWAS779392_HHumanhigh density lipoprotein cholesterol measurement  IAGPrs861369405850206 GWAS_CATALOGPMID:38448586
Experimental Data Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1605432RAC1Rac family small GTPase 1763745276403967Human

Position Markers

Peak: (rs861369)
Human AssemblyChrPosition (strand)Source
GRCh3876,379,702 - 6,379,703RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1643402BMD2_HBone mineral density QTL 2 (human)2.690.0002Bone mineral density7122435431Human
407130416GWAS779392_Hesterified cholesterol measurement, high density lipoprotein cholesterol measurement QTL GWAS779392 (human)6e-13esterified cholesterol measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)763797026379703Human
1643247BW130_HBody Weight QTL 130 (human)1.280.008Body weightbody mass index7117453493Human
1643391BW322_HBody weight QTL 322 (human)2.690.0002Body fat amount7122435431Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS779392_H GCST90302128 Cholesterol esters in very large HDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals C 0.5055 6E-13 12.222 rs861369 0.0292 esterified cholesterol measurement (EFO:0008589)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:38448586
Database Acc Id Source(s)
GWAS Catalog GCST90302128 GWAS Catalog

RGD Curation Notes
Note Type Note Reference