GWAS768731_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS768731_H (smoking initiation QTL GWAS768731 (human)) Homo sapiens

Symbol: GWAS768731_H
Name: smoking initiation QTL GWAS768731 (human)
RGD ID: 407119755
Trait: smoking initiation
LOD Score: Not Available
P Value: 6.0E-10
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38349,291,400 - 49,291,401RGD_MAPPER_PIPELINEGRCh38
GRCh37349,328,833 - 49,328,834RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS768731_HHumansmoking initiation  IAGPrs9811047405850206 GWAS_CATALOGPMID:30643251
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1344173USP4ubiquitin specific peptidase 434927714449340053Human

Position Markers

Peak: (rs9811047)
Human AssemblyChrPosition (strand)Source
GRCh38349,291,400 - 49,291,401RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
406964467GWAS613443_Halcohol use disorder measurement QTL GWAS613443 (human)5e-12alcohol use disorder measurement34929140049291401Human
406971267GWAS620243_Hopioid use disorder QTL GWAS620243 (human)7e-11conditioned place preference behavior trait (VT:0010723)34929140049291401Human
1298487BFD1_HBody fluid distribution QTL 1 (human)3.94Body fluid distributionimpedance ratio33638071262380712Human
1298489RA4_HRheumatoid arthritis QTL 4 (human)0.0283Joint/bone inflammationrheumatoid arthritis33638071262380712Human
1643509BW293_HBody Weight QTL 293 (human)1.42Body weightBMI33638071262380712Human
2316061GLUCO194_HGlucose level QTL 194 (human)0.02Glucose level32338077449380774Human
2289308BW392_HBody weight QTL 392 (human)1.42Body weightBMI33638071262380712Human
407119755GWAS768731_Hsmoking initiation QTL GWAS768731 (human)6e-10smoking initiation34929140049291401Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS613443_H GCST90296428 Alcohol use disorder (MTAG) 171,601 European ancestry individuals (MTAG effective sample size boosted by opioid use disorder, cannabis use disorder, smoking samples) ? NR 5E-12 11.302 rs9811047 0.02096281 alcohol use disorder measurement (EFO:0009458)
 PMID:37156939
GWAS620243_H GCST90296425 Opioid use disorder (MTAG) 74,635 European ancestry individuals (MTAG effective sample size boosted by cannabis use disorder, alcohol use disorder, smoking samples) ? NR 7E-11 10.155 rs9811047 0.02465197 opioid use disorder (EFO:0010702)
 PMID:37156939
GWAS768731_H GCST007462 Age of smoking initiation (MTAG) up to 931,815 European ancestry individuals C 0.742 6E-10 9.222 rs9811047 0.0103184 smoking initiation (EFO:0005670)
 PMID:30643251
Database Acc Id Source(s)
GWAS Catalog GCST007462 GWAS Catalog

RGD Curation Notes
Note Type Note Reference