GWAS767253_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS767253_H (phospholipids in IDL measurement QTL GWAS767253 (human)) Homo sapiens

Symbol: GWAS767253_H
Name: phospholipids in IDL measurement QTL GWAS767253 (human)
RGD ID: 407118277
Trait: adipose unsaturated fatty acid amount   (VT:0005285)    
milk polyunsaturated fatty acid amount   (VT:0010374)    
Measurement Type: blood intermediate density lipoprotein cholesterol level   (CMO:0001562)    
blood intermediate density lipoprotein phospholipid level   (CMO:0001574)    
blood lipid measurement   (CMO:0000050)    
milk polyunsaturated fatty acid measurement   (CMO:0000821)    
LOD Score: Not Available
P Value: 5.0E-10
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh382017,864,040 - 17,864,041RGD_MAPPER_PIPELINEGRCh38
GRCh372017,844,684 - 17,844,685RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS767253_HHumanblood intermediate density lipoprotein cholesterol level  IAGPrs2618566405850206Based on the EFO term IDGWAS_CATALOGPMID:35213538
GWAS767253_HHumanblood intermediate density lipoprotein phospholipid level  IAGPrs2618566405850206Based on the EFO term IDGWAS_CATALOGPMID:36764567
GWAS767253_HHumanblood lipid measurement  IAGPrs2618566405850206Based on the EFO term IDGWAS_CATALOGPMID:35213538
GWAS767253_HHumanmilk polyunsaturated fatty acid measurement  IAGPrs2618566405850206Based on the EFO term IDGWAS_CATALOGPMID:38448586

Vertebrate Trait
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS767253_HHumanadipose unsaturated fatty acid amount  IAGPrs2618566405850206Based on the EFO term IDGWAS_CATALOGPMID:38448586
GWAS767253_HHumanmilk polyunsaturated fatty acid amount  IAGPrs2618566405850206Based on the EFO term IDGWAS_CATALOGPMID:38448586

Experimental Factor Annotations    Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Position Markers

Peak: (rs2618566)
Human AssemblyChrPosition (strand)Source
GRCh382017,864,040 - 17,864,041RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407090243GWAS739219_Hfree cholesterol to total lipids in medium VLDL percentage QTL GWAS739219 (human)4e-15phospholipids:total lipids ratio201786404017864041Human
407118277GWAS767253_Hphospholipids in IDL measurement QTL GWAS767253 (human)5e-10milk polyunsaturated fatty acid amount (VT:0010374)blood intermediate density lipoprotein cholesterol level (CMO:0001562)201786404017864041Human
407079874GWAS728850_Hcholesterol to total lipids in small VLDL percentage QTL GWAS728850 (human)2e-12triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)201786404017864041Human
407253829GWAS902805_Htriglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement QTL GWAS902805 (human)2e-13HMG CoA reductase inhibitor use measurementblood very low density lipoprotein cholesterol level (CMO:0000648)201786404017864041Human
407024198GWAS673174_Htriglycerides to total lipids in very large VLDL percentage QTL GWAS673174 (human)3e-13triglycerides to total lipids in very large VLDL percentage 201786404017864041Human
407078983GWAS727959_Htriglycerides to total lipids in small VLDL percentage QTL GWAS727959 (human)1e-12triglycerides to total lipids in small VLDL percentage 201786404017864041Human
407259969GWAS908945_Hvery low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio QTL GWAS908945 (human)6e-13very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratioblood very low density lipoprotein cholesterol level (CMO:0000648)201786404017864041Human
407075275GWAS724251_Homega-6 polyunsaturated fatty acid measurement QTL GWAS724251 (human)1e-10very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratioblood very low density lipoprotein cholesterol level (CMO:0000648)201786404017864041Human
407216205GWAS865181_Hfree cholesterol measurement, low density lipoprotein cholesterol measurement QTL GWAS865181 (human)6e-10free cholesterol measurement, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)201786404017864041Human
407189196GWAS838172_Hlow density lipoprotein cholesterol measurement, phospholipid measurement QTL GWAS838172 (human)4e-08apolipoprotein B measurementblood apoliprotein B level (CMO:0000522)201786404017864041Human
407189577GWAS838553_Hcholesteryl ester measurement, low density lipoprotein cholesterol measurement QTL GWAS838553 (human)3e-08blood lipid amount (VT:0003949)blood low density lipoprotein cholesterol level (CMO:0000053)201786404017864041Human
407314378GWAS963354_Hvery low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio QTL GWAS963354 (human)7e-10very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratioblood very low density lipoprotein cholesterol level (CMO:0000648)201786404017864041Human
407345866GWAS994842_Htotal cholesterol measurement QTL GWAS994842 (human)3e-98total cholesterol measurementblood total cholesterol level (CMO:0000051)201786404017864041Human
407156299GWAS805275_Hlow density lipoprotein cholesterol measurement QTL GWAS805275 (human)1e-29low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)201786404017864041Human
407301705GWAS950681_Hlow density lipoprotein cholesterol measurement QTL GWAS950681 (human)9e-22low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)201786404017864041Human
407240394GWAS889370_Hintermediate density lipoprotein measurement QTL GWAS889370 (human)9e-09low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)201786404017864041Human
407023314GWAS672290_Hcholesteryl esters to total lipids in very large VLDL percentage QTL GWAS672290 (human)3e-12very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratioblood very low density lipoprotein cholesterol level (CMO:0000648)201786404017864041Human
407215061GWAS864037_Hlow density lipoprotein cholesterol measurement QTL GWAS864037 (human)2e-08free cholesterol measurement, low density lipoprotein cholesterol measurementblood cholesterol level (CMO:0002280)201786404017864041Human
407095894GWAS744870_Hcholesterol esters in medium LDL measurement QTL GWAS744870 (human)2e-23cholesterol esters in medium LDL measurement201786404017864041Human
407295455GWAS944431_Hvery low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio QTL GWAS944431 (human)5e-14very low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratioblood very low density lipoprotein cholesterol level (CMO:0000648)201786404017864041Human
407317470GWAS966446_Hvery low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio QTL GWAS966446 (human)4e-12very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratioblood very low density lipoprotein cholesterol level (CMO:0000648)201786404017864041Human
407128159GWAS777135_Hphospholipids in small LDL measurement QTL GWAS777135 (human)9e-16phospholipids in small LDL measurement 201786404017864041Human
407156312GWAS805288_Hapolipoprotein B measurement QTL GWAS805288 (human)3e-43apolipoprotein B measurementblood apoliprotein B level (CMO:0000522)201786404017864041Human
407086174GWAS735150_Hlow density lipoprotein cholesterol measurement, lipid measurement QTL GWAS735150 (human)8e-22low density lipoprotein cholesterol measurement, lipid measurementblood lipid measurement (CMO:0000050)201786404017864041Human
407096541GWAS745517_Hcholesteryl esters to total lipids in large VLDL percentage QTL GWAS745517 (human)1e-13very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratioblood very low density lipoprotein cholesterol level (CMO:0000648)201786404017864041Human
407317464GWAS966440_Hlow density lipoprotein cholesterol measurement, phospholipid measurement QTL GWAS966440 (human)1e-11low density lipoprotein cholesterol measurement, phospholipid measurementblood low density lipoprotein cholesterol level (CMO:0000053)201786404017864041Human
407269465GWAS918441_Htotal cholesterol measurement, intermediate density lipoprotein measurement QTL GWAS918441 (human)8e-10total cholesterol measurement, intermediate density lipoprotein measurementblood intermediate density lipoprotein cholesterol level (CMO:0001562)201786404017864041Human
407125348GWAS774324_Hlow density lipoprotein cholesterol measurement QTL GWAS774324 (human)1e-20low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)201786404017864041Human
407123684GWAS772660_Hfree cholesterol in small LDL measurement QTL GWAS772660 (human)7e-18free cholesterol in small LDL measurement 201786404017864041Human
407117541GWAS766517_Hfree cholesterol in IDL measurement QTL GWAS766517 (human)1e-09free cholesterol in IDL measurementblood intermediate density lipoprotein cholesterol level (CMO:0001562)201786404017864041Human
407213283GWAS862259_Hlow density lipoprotein particle size measurement QTL GWAS862259 (human)4e-09total cholesterol measurement, very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)201786404017864041Human
407060971GWAS709947_Hesterified cholesterol measurement QTL GWAS709947 (human)8e-17esterified cholesterol measurement201786404017864041Human
407081194GWAS730170_Hcholesteryl esters to total lipids in small VLDL percentage QTL GWAS730170 (human)5e-11total cholesterol measurementblood total cholesterol level (CMO:0000051)201786404017864041Human
407118446GWAS767422_Htotal cholesterol measurement, low density lipoprotein cholesterol measurement QTL GWAS767422 (human)3e-23total cholesterol measurement, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)201786404017864041Human
407331307GWAS980283_Hvery low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio QTL GWAS980283 (human)5e-09very low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratioblood very low density lipoprotein cholesterol level (CMO:0000648)201786404017864041Human
407081838GWAS730814_Hfree cholesterol to total lipids in small VLDL percentage QTL GWAS730814 (human)3e-11phospholipid measurement, intermediate density lipoprotein measurementblood intermediate density lipoprotein cholesterol level (CMO:0001562)201786404017864041Human
407087982GWAS736958_Hlinoleic acid measurement QTL GWAS736958 (human)8e-11free cholesterol measurement, intermediate density lipoprotein measurementblood intermediate density lipoprotein cholesterol level (CMO:0001562)201786404017864041Human
406973679GWAS622655_Hgallstones QTL GWAS622655 (human)2e-10triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)201786404017864041Human
407023602GWAS672578_Hfree cholesterol to total lipids in very large VLDL percentage QTL GWAS672578 (human)6e-12free cholesterol to total lipids in very large VLDL percentage 201786404017864041Human
407077751GWAS726727_Hfree cholesterol measurement QTL GWAS726727 (human)9e-17free cholesterol measurementblood cholesterol level (CMO:0002280)201786404017864041Human
407091574GWAS740550_Hlow density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio QTL GWAS740550 (human)8e-21free cholesterol in medium LDL measurement blood low density lipoprotein cholesterol level (CMO:0000053)201786404017864041Human
407079162GWAS728138_Hphospholipids:total lipids ratio QTL GWAS728138 (human)8e-12very low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratioblood very low density lipoprotein cholesterol level (CMO:0000648)201786404017864041Human
407120645GWAS769621_Htotal cholesterol measurement QTL GWAS769621 (human)7e-17total cholesterol measurementblood total cholesterol level (CMO:0000051)201786404017864041Human
407314053GWAS963029_Hlow density lipoprotein cholesterol measurement QTL GWAS963029 (human)4e-153low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)201786404017864041Human
407097600GWAS746576_Hcholesterol to total lipids in medium VLDL percentage QTL GWAS746576 (human)6e-14cholesterol to total lipids in medium VLDL percentage 201786404017864041Human
407086212GWAS735188_Hlow density lipoprotein cholesterol measurement QTL GWAS735188 (human)1e-21low density lipoprotein cholesterol measurement, phospholipids:total lipids ratioblood low density lipoprotein cholesterol level (CMO:0000053)201786404017864041Human
407089419GWAS738395_Htriglycerides to total lipids in medium VLDL percentage QTL GWAS738395 (human)1e-14triglycerides to total lipids in medium VLDL percentage 201786404017864041Human
407120777GWAS769753_Hlow density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio QTL GWAS769753 (human)4e-20low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratioblood low density lipoprotein cholesterol level (CMO:0000053)201786404017864041Human
407324042GWAS973018_Htotal cholesterol measurement QTL GWAS973018 (human)6e-74total cholesterol measurementblood total cholesterol level (CMO:0000051)201786404017864041Human
407247112GWAS896088_Hcholesteryl ester measurement, intermediate density lipoprotein measurement QTL GWAS896088 (human)3e-09blood lipid amount (VT:0003949)blood very low density lipoprotein cholesterol level (CMO:0000648)201786404017864041Human
407181194GWAS830170_Hvery low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio QTL GWAS830170 (human)2e-09blood lipid amount (VT:0003949)blood very low density lipoprotein cholesterol level (CMO:0000648)201786404017864041Human
407316744GWAS965720_Hfree cholesterol measurement, low density lipoprotein cholesterol measurement QTL GWAS965720 (human)2e-11free cholesterol measurement, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)201786404017864041Human
407124500GWAS773476_Hesterified cholesterol measurement, low density lipoprotein cholesterol measurement QTL GWAS773476 (human)1e-23esterified cholesterol measurement, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)201786404017864041Human
407094803GWAS743779_Hcholesterol esters in large LDL measurement QTL GWAS743779 (human)2e-22low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)201786404017864041Human
406993040GWAS642016_Hlow density lipoprotein cholesterol measurement QTL GWAS642016 (human)9e-11blood lipid amount (VT:0003949)blood very low density lipoprotein cholesterol level (CMO:0000648)201786404017864041Human
407142679GWAS791655_Hlow density lipoprotein cholesterol measurement QTL GWAS791655 (human)1e-15low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)201786404017864041Human
407190172GWAS839148_Hlow density lipoprotein cholesterol measurement, lipid measurement QTL GWAS839148 (human)1e-08very low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratioblood very low density lipoprotein cholesterol level (CMO:0000648)201786404017864041Human
407142680GWAS791656_Hlow density lipoprotein cholesterol measurement QTL GWAS791656 (human)1e-16low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)201786404017864041Human
407088159GWAS737135_Hcholesteryl esters to total lipids in medium VLDL percentage QTL GWAS737135 (human)4e-13cholesteryl esters to total lipids in medium VLDL percentage 201786404017864041Human
407189019GWAS837995_Htotal cholesterol measurement, low density lipoprotein cholesterol measurement QTL GWAS837995 (human)7e-09total cholesterol measurement, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)201786404017864041Human
407326873GWAS975849_Hlow density lipoprotein cholesterol measurement QTL GWAS975849 (human)5e-117low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)201786404017864041Human
1643385BW311_HBody weight QTL 311 (human)3.310.0001Body fat amount20734547523289549Human
407121189GWAS770165_Htotal cholesterol in medium LDL QTL GWAS770165 (human)5e-23total cholesterol in medium LDL201786404017864041Human
407188391GWAS837367_Hfree cholesterol measurement, low density lipoprotein cholesterol measurement QTL GWAS837367 (human)4e-10free cholesterol measurement, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)201786404017864041Human
407125793GWAS774769_Hcholesterol:total lipids ratio, cholesteryl esters:total lipids ratio QTL GWAS774769 (human)6e-22cholesterol:total lipids ratio, cholesteryl esters:total lipids ratio201786404017864041Human
407329058GWAS978034_Hnon-high density lipoprotein cholesterol measurement QTL GWAS978034 (human)7e-66non-high density lipoprotein cholesterol measurementblood non-high density lipoprotein cholesterol level (CMO:0003967)201786404017864041Human
407023919GWAS672895_Hcholesterol to total lipids in very large VLDL percentage QTL GWAS672895 (human)7e-13cholesterol to total lipids in very large VLDL percentage 201786404017864041Human
1643383BW312_HBody weight QTL 312 (human)2.920.0004Body fat amountpercent fat20734547523289549Human
407126581GWAS775557_Htotal lipids in small LDL QTL GWAS775557 (human)5e-21total lipids in small LDL201786404017864041Human
407105077GWAS754053_Htotal lipids in large LDL QTL GWAS754053 (human)5e-22total lipids in large LDL201786404017864041Human
407333951GWAS982927_Hnon-high density lipoprotein cholesterol measurement QTL GWAS982927 (human)3e-85non-high density lipoprotein cholesterol measurementblood non-high density lipoprotein cholesterol level (CMO:0003967)201786404017864041Human
407128765GWAS777741_Htotal cholesterol in small LDL QTL GWAS777741 (human)1e-22low density lipoprotein cholesterol measurement, physical activityblood low density lipoprotein cholesterol level (CMO:0000053)201786404017864041Human
407083578GWAS732554_Htotal cholesterol in large LDL QTL GWAS732554 (human)4e-23low density lipoprotein cholesterol measurement, phospholipids:total lipids ratioblood low density lipoprotein cholesterol level (CMO:0000053)201786404017864041Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS622655_H GCST90128518 Gallstone disease 43,639 European ancestry cases, 506,798 European ancestry controls T NR 2E-10 9.699 rs2618566 1.05 gallstones (EFO:0004210)
 PMID:34651315
GWAS642016_H GCST011347 Low density lipoprotein cholesterol levels 76,081 European ancestry individuals, 127,395 Japanese ancestry individuals ? NR 9E-11 10.046 rs2618566 0.0308 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:33339817
GWAS672290_H GCST90269683 Cholesteryl esters to total lipids in very large VLDL percentage (UKB data field 23586) 87,620 European ancestry individuals G 0.339843 3E-12 11.523 rs2618566 0.0336139 cholesteryl esters to total lipids in very large VLDL percentage (EFO:0022258)
 PMID:36764567
GWAS672578_H GCST90269684 Free cholesterol to total lipids in very large VLDL percentage (UKB data field 23587) 87,620 European ancestry individuals G 0.339843 6E-12 11.222 rs2618566 0.0333129 free cholesterol to total lipids in very large VLDL percentage (EFO:0022289)
 PMID:36764567
GWAS672895_H GCST90269682 Cholesterol to total lipids in very large VLDL percentage (UKB data field 23585) 87,620 European ancestry individuals G 0.339843 7E-13 12.155 rs2618566 0.0344957 cholesterol to total lipids in very large VLDL percentage (EFO:0022244)
 PMID:36764567
GWAS673174_H GCST90269685 Triglycerides to total lipids in very large VLDL percentage (UKB data field 23588) 87,620 European ancestry individuals G 0.339843 3E-13 12.523 rs2618566 0.0355047 triglycerides to total lipids in very large VLDL percentage (EFO:0022340)
 PMID:36764567
GWAS709947_H GCST90301957 Esterified cholesterol levels 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.652 8E-17 16.097 rs2618566 0.0355 esterified cholesterol measurement (EFO:0008589)
 PMID:38448586
GWAS724251_H GCST90301961 Omega-6 fatty acids levels 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.6519 1E-10 10 rs2618566 0.0273 omega-6 polyunsaturated fatty acid measurement (EFO:0005680)
 PMID:38448586
GWAS726727_H GCST90301963 Free cholesterol levels 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.652 9E-17 16.046 rs2618566 0.0353 free cholesterol measurement (EFO:0008591)
 PMID:38448586
GWAS727959_H GCST90269700 Triglycerides to total lipids in small VLDL percentage (UKB data field 23603) 88,329 European ancestry individuals G 0.339826 1E-12 12 rs2618566 0.0345274 triglycerides to total lipids in small VLDL percentage (EFO:0022338)
 PMID:36764567
GWAS728138_H GCST90269696 Phospholipids to total lipids in small VLDL percentage (UKB data field 23599) 88,329 European ancestry individuals G 0.339826 8E-12 11.097 rs2618566 0.032838 phospholipids:total lipids ratio (EFO:0020946)
 PMID:36764567
GWAS728850_H GCST90269697 Cholesterol to total lipids in small VLDL percentage (UKB data field 23600) 88,329 European ancestry individuals G 0.339826 2E-12 11.699 rs2618566 0.0344977 cholesterol to total lipids in small VLDL percentage (EFO:0022242)
 PMID:36764567
GWAS730170_H GCST90269698 Cholesteryl esters to total lipids in small VLDL percentage (UKB data field 23601) 88,329 European ancestry individuals G 0.339826 5E-11 10.302 rs2618566 0.03262 cholesteryl esters to total lipids in small VLDL percentage (EFO:0022256)
 PMID:36764567
GWAS730814_H GCST90269699 Free cholesterol to total lipids in small VLDL percentage (UKB data field 23602) 88,329 European ancestry individuals G 0.339826 3E-11 10.523 rs2618566 0.0317396 free cholesterol to total lipids in small VLDL percentage (EFO:0022287)
 PMID:36764567
GWAS732554_H GCST90302007 Total cholesterol in large LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.652 4E-23 22.398 rs2618566 0.0422 total cholesterol in large LDL (EFO:0022167)
 PMID:38448586
GWAS735150_H GCST90302049 Total lipid levels in medium LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.652 8E-22 21.097 rs2618566 0.0409 low density lipoprotein cholesterol measurement (EFO:0004611)
lipid measurement (EFO:0004529)
 PMID:38448586
GWAS735188_H GCST90302050 Concentration of medium LDL particles 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.652 1E-21 21 rs2618566 0.0407 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:38448586
GWAS736958_H GCST90301988 Linoleic acid (18:2) levels 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.652 8E-11 10.097 rs2618566 0.0276 linoleic acid measurement (EFO:0006807)
 PMID:38448586
GWAS737135_H GCST90269693 Cholesteryl esters to total lipids in medium VLDL percentage (UKB data field 23596) 88,329 European ancestry individuals G 0.339826 4E-13 12.398 rs2618566 0.0342657 cholesteryl esters to total lipids in medium VLDL percentage (EFO:0022253)
 PMID:36764567
GWAS738395_H GCST90269695 Triglycerides to total lipids in medium VLDL percentage (UKB data field 23598) 88,329 European ancestry individuals G 0.339826 1E-14 14 rs2618566 0.0366383 triglycerides to total lipids in medium VLDL percentage (EFO:0022335)
 PMID:36764567
GWAS739219_H GCST90269694 Free cholesterol to total lipids in medium VLDL percentage (UKB data field 23597) 88,329 European ancestry individuals G 0.339826 4E-15 14.398 rs2618566 0.0376256 free cholesterol to total lipids in medium VLDL percentage (EFO:0022284)
 PMID:36764567
GWAS740550_H GCST90302046 Cholesteryl esters to total lipids ratio in medium LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.6521 8E-21 20.097 rs2618566 0.0397 low density lipoprotein cholesterol measurement (EFO:0004611)
cholesteryl esters:total lipids ratio (EFO:0020944)
 PMID:38448586
None Available GCST90269734 Free cholesterol to total lipids in large HDL percentage (UKB data field 23637) 88,329 European ancestry individuals G 0.339826 3E-12 11.523 rs2618566 0.0326392 free cholesterol to total lipids in large HDL percentage (EFO:0022279)
 PMID:36764567
None Available GCST90302047 Free cholesterol in medium LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.652 8E-21 20.097 rs2618566 0.0398 free cholesterol in medium LDL measurement (EFO:0022268)
 PMID:38448586
GWAS743779_H GCST90302009 Cholesterol esters in large LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.652 2E-22 21.699 rs2618566 0.0417 cholesterol esters in large LDL measurement (EFO:0022165)
 PMID:38448586
GWAS744870_H GCST90302045 Cholesterol esters in medium LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.652 2E-23 22.699 rs2618566 0.0425 cholesterol esters in medium LDL measurement (EFO:0022186)
 PMID:38448586
GWAS745517_H GCST90269688 Cholesteryl esters to total lipids in large VLDL percentage (UKB data field 23591) 88,321 European ancestry individuals G 0.339817 1E-13 13 rs2618566 0.0355596 cholesteryl esters to total lipids in large VLDL percentage (EFO:0022250)
 PMID:36764567
None Available GCST90269687 Cholesterol to total lipids in large VLDL percentage (UKB data field 23590) 88,321 European ancestry individuals G 0.339817 2E-12 11.699 rs2618566 0.0344923 cholesterol to total lipids in large VLDL percentage (EFO:0022236)
 PMID:36764567
GWAS746576_H GCST90269692 Cholesterol to total lipids in medium VLDL percentage (UKB data field 23595) 88,329 European ancestry individuals G 0.339826 6E-14 13.222 rs2618566 0.0355384 cholesterol to total lipids in medium VLDL percentage (EFO:0022239)
 PMID:36764567
None Available GCST90269691 Phospholipids to total lipids in medium VLDL percentage (UKB data field 23594) 88,329 European ancestry individuals G 0.339826 4E-15 14.398 rs2618566 0.0378057 phospholipids:total lipids ratio (EFO:0020946)
 PMID:36764567
GWAS754053_H GCST90302013 Total lipids in large LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.652 5E-22 21.302 rs2618566 0.0411 total lipids in large LDL (EFO:0022163)
 PMID:38448586
None Available GCST90302016 Phospholipids to total lipids ratio in large LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.6526 4E-23 22.398 rs2618566 0.0408 low density lipoprotein cholesterol measurement (EFO:0004611)
phospholipids:total lipids ratio (EFO:0020946)
 PMID:38448586
GWAS766517_H GCST90269625 Free cholesterol in IDL (UKB data field 23528) 88,329 European ancestry individuals G 0.339826 1E-9 9 rs2618566 0.0295659 free cholesterol in IDL measurement (EFO:0022181)
 PMID:36764567
GWAS767253_H GCST90269622 Phospholipids in IDL (UKB data field 23525) 88,329 European ancestry individuals G 0.339826 5E-10 9.302 rs2618566 0.0299975 phospholipids in IDL measurement (EFO:0022164)
 PMID:36764567
GWAS767422_H GCST90301991 Total cholesterol levels in LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.652 3E-23 22.523 rs2618566 0.0423 total cholesterol measurement (EFO:0004574)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:38448586
GWAS769621_H GCST90302075 Serum total cholesterol levels 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.6521 7E-17 16.155 rs2618566 0.0354 total cholesterol measurement (EFO:0004574)
 PMID:38448586
GWAS769753_H GCST90302096 Free cholesterol to total lipids ratio in small LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.6523 4E-20 19.398 rs2618566 0.038 low density lipoprotein cholesterol measurement (EFO:0004611)
free cholesterol:total lipids ratio (EFO:0020945)
 PMID:38448586
None Available GCST90302071 Polyunsaturated fatty acids 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.652 5E-10 9.302 rs2618566 0.0265 polyunsaturated fatty acid measurement (EFO:0010733)
 PMID:38448586
GWAS770165_H GCST90302043 Total cholesterol in medium LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.652 5E-23 22.302 rs2618566 0.0421 total cholesterol in medium LDL (EFO:0022185)
 PMID:38448586
GWAS772660_H GCST90302095 Free cholesterol in small LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.6521 7E-18 17.155 rs2618566 0.0366 free cholesterol in small LDL measurement (EFO:0022271)
 PMID:38448586
None Available GCST90302014 Concentration of large LDL particles 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.652 1E-21 21 rs2618566 0.0407 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:38448586
GWAS773476_H GCST90302093 Cholesterol esters in small LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.652 1E-23 23 rs2618566 0.0428 esterified cholesterol measurement (EFO:0008589)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:38448586
GWAS774324_H GCST90302098 Concentration of small LDL particles 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.652 1E-20 20 rs2618566 0.0398 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:38448586
GWAS774769_H GCST90302094 Cholesteryl esters to total lipids ratio in small LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.6521 6E-22 21.222 rs2618566 0.0408 cholesterol:total lipids ratio (EFO:0020943)
cholesteryl esters:total lipids ratio (EFO:0020944)
 PMID:38448586
GWAS775557_H GCST90302097 Total lipids in small LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.652 5E-21 20.302 rs2618566 0.0401 total lipids in small LDL (EFO:0022168)
 PMID:38448586
GWAS777135_H GCST90302099 Phospholipids in small LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.652 9E-16 15.046 rs2618566 0.0343 phospholipids in small LDL measurement (EFO:0022297)
 PMID:38448586
GWAS777741_H GCST90302091 Total Cholesterol in small LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.652 1E-22 22 rs2618566 0.0418 total cholesterol in small LDL (EFO:0022179)
 PMID:38448586
None Available GCST90302052 Phospholipids to total lipids ratio in medium LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.6527 1E-21 21 rs2618566 0.0392 low density lipoprotein cholesterol measurement (EFO:0004611)
phospholipids:total lipids ratio (EFO:0020946)
 PMID:38448586
GWAS791655_H GCST007141 Low density lipoprotein cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G 0.35 1E-15 15 rs2618566 0.04 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:29507422
GWAS791656_H GCST007141 Low density lipoprotein cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G NR 1E-16 16 rs2618566 0.038 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:29507422
None Available GCST90302103 Sphingomyelins levels 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 110,896 European ancestry individuals T 0.6513 3E-11 10.523 rs2618566 0.0289 sphingomyelin measurement (EFO:0010118)
 PMID:38448586
None Available GCST007284 LDL cholesterol x physical activity interaction (2df test) 7,260 African American inactive individuals, 12,761 African American active individuals, 2,740 Asian ancestry inactive individuals, 3,615 Asian ancestry active individuals, 22,378 European ancestry inactive individuals, 55,310 European ancestry active individuals, 2,163 Hispanic or Latin American inactive individuals, 3,461 Hispanic or Latin American active individuals T 0.6441 1E-22 22 rs2618566 N/A low density lipoprotein cholesterol measurement (EFO:0004611)
physical activity (EFO:0003940)
 PMID:30670697
GWAS805275_H GCST010245 LDL cholesterol levels 440,546 European ancestry individuals G 0.340138 1E-29 29 rs2618566 0.0248873 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:32203549
GWAS805288_H GCST010243 Apolipoprotein B levels 439,214 European ancestry individuals G 0.340098 3E-43 42.523 rs2618566 0.0302601 apolipoprotein B measurement (EFO:0004615)
 PMID:32203549
None Available GCST007143 Total cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G 0.35 2E-10 9.699 rs2618566 0.031 total cholesterol measurement (EFO:0004574)
 PMID:29507422
None Available GCST007143 Total cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G NR 5E-11 10.302 rs2618566 0.029 total cholesterol measurement (EFO:0004574)
 PMID:29507422
GWAS830170_H GCST90092869 Cholesterol to total lipids ratio in large VLDL 115,071 European ancestry individuals G 0.339695 2E-9 8.699 rs2618566 0.0254803 very low density lipoprotein cholesterol measurement (EFO:0008317)
cholesterol:total lipids ratio (EFO:0020943)
 PMID:35213538
None Available GCST90092871 Cholesteryl esters to total lipids ratio in large VLDL 115,071 European ancestry individuals G 0.339695 1E-10 10 rs2618566 0.0268947 very low density lipoprotein cholesterol measurement (EFO:0008317)
cholesteryl esters:total lipids ratio (EFO:0020944)
 PMID:35213538
GWAS837367_H GCST90092860 Free cholesterol levels in large LDL 115,082 European ancestry individuals G 0.339706 4E-10 9.398 rs2618566 0.0268914 free cholesterol measurement (EFO:0008591)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
GWAS837995_H GCST90092856 Cholesterol levels in large LDL 115,082 European ancestry individuals G 0.339706 7E-9 8.155 rs2618566 0.0249497 total cholesterol measurement (EFO:0004574)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
GWAS838172_H GCST90092864 Phospholipid levels in large LDL 115,082 European ancestry individuals G 0.339706 4E-8 7.398 rs2618566 0.0237902 low density lipoprotein cholesterol measurement (EFO:0004611)
phospholipid measurement (EFO:0004639)
 PMID:35213538
GWAS838553_H GCST90092858 Cholesteryl ester levels in large LDL 115,082 European ancestry individuals G 0.339706 3E-8 7.523 rs2618566 0.0239912 cholesteryl ester measurement (EFO:0010351)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
GWAS839148_H GCST90092862 Total lipid levels in large LDL 115,082 European ancestry individuals G 0.339706 1E-8 8 rs2618566 0.0244783 low density lipoprotein cholesterol measurement (EFO:0004611)
lipid measurement (EFO:0004529)
 PMID:35213538
None Available GCST90092863 Concentration of large LDL particles 115,082 European ancestry individuals G 0.339706 2E-10 9.699 rs2618566 0.0277973 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
None Available GCST90092888 Phospholipid levels in LDL 115,082 European ancestry individuals G 0.339706 4E-8 7.398 rs2618566 0.0238711 low density lipoprotein cholesterol measurement (EFO:0004611)
phospholipid measurement (EFO:0004639)
 PMID:35213538
GWAS862259_H GCST90092889 Average diameter for LDL particles 115,082 European ancestry individuals G 0.339706 4E-9 8.398 rs2618566 0.0250359 low density lipoprotein particle size measurement (EFO:0008593)
 PMID:35213538
GWAS864037_H GCST90092887 Concentration of LDL particles 115,082 European ancestry individuals G 0.339706 2E-8 7.699 rs2618566 0.0246343 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
GWAS865181_H GCST90092885 Free cholesterol levels in LDL 115,082 European ancestry individuals G 0.339706 6E-10 9.222 rs2618566 0.0267168 free cholesterol measurement (EFO:0008591)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
None Available GCST90092839 Phospholipid levels in IDL 115,082 European ancestry individuals G 0.339706 3E-11 10.523 rs2618566 0.0280546 phospholipid measurement (EFO:0004639)
intermediate density lipoprotein measurement (EFO:0008595)
 PMID:35213538
GWAS889370_H GCST90092838 Concentration of IDL particles 115,082 European ancestry individuals G 0.339706 9E-9 8.046 rs2618566 0.0248274 intermediate density lipoprotein measurement (EFO:0008595)
 PMID:35213538
None Available GCST90092837 Total lipid levels in IDL 115,082 European ancestry individuals G 0.339706 5E-10 9.302 rs2618566 0.0261761 lipid measurement (EFO:0004529)
intermediate density lipoprotein measurement (EFO:0008595)
 PMID:35213538
None Available GCST90092835 Free cholesterol levels in IDL 115,082 European ancestry individuals G 0.339706 8E-11 10.097 rs2618566 0.0274304 free cholesterol measurement (EFO:0008591)
intermediate density lipoprotein measurement (EFO:0008595)
 PMID:35213538
GWAS896088_H GCST90092833 Cholesteryl ester levels in IDL 115,082 European ancestry individuals G 0.339706 3E-9 8.523 rs2618566 0.0250956 cholesteryl ester measurement (EFO:0010351)
intermediate density lipoprotein measurement (EFO:0008595)
 PMID:35213538
GWAS902805_H GCST90092927 Triglycerides to total lipids ratio in medium VLDL 115,082 European ancestry individuals G 0.339706 2E-13 12.699 rs2618566 0.0303145 triglycerides:total lipids ratio (EFO:0020947)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
None Available GCST90092908 Free cholesterol levels in medium LDL 115,082 European ancestry individuals G 0.339706 2E-8 7.699 rs2618566 0.0243187 free cholesterol measurement (EFO:0008591)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
GWAS908945_H GCST90092917 Cholesterol to total lipids ratio in medium VLDL 115,082 European ancestry individuals G 0.339706 6E-13 12.222 rs2618566 0.0295119 very low density lipoprotein cholesterol measurement (EFO:0008317)
cholesterol:total lipids ratio (EFO:0020943)
 PMID:35213538
GWAS918441_H GCST90092831 Cholesterol levels in IDL 115,082 European ancestry individuals G 0.339706 8E-10 9.097 rs2618566 0.0258585 total cholesterol measurement (EFO:0004574)
intermediate density lipoprotein measurement (EFO:0008595)
 PMID:35213538
None Available GCST90092916 Cholesterol levels in medium VLDL 115,082 European ancestry individuals G 0.339706 1E-8 8 rs2618566 0.0246515 total cholesterol measurement (EFO:0004574)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
None Available GCST90092925 Phospholipids to total lipids ratio in medium VLDL 115,082 European ancestry individuals G 0.339706 1E-13 13 rs2618566 0.0309484 very low density lipoprotein cholesterol measurement (EFO:0008317)
phospholipids:total lipids ratio (EFO:0020946)
 PMID:35213538
GWAS944431_H GCST90092921 Free cholesterol to total lipids ratio in medium VLDL 115,082 European ancestry individuals G 0.339706 5E-14 13.302 rs2618566 0.0312681 very low density lipoprotein cholesterol measurement (EFO:0008317)
free cholesterol:total lipids ratio (EFO:0020945)
 PMID:35213538
None Available GCST90092918 Cholesteryl ester levels in medium VLDL 115,082 European ancestry individuals G 0.339706 9E-11 10.046 rs2618566 0.0279896 cholesteryl ester measurement (EFO:0010351)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
None Available GCST90092919 Cholesteryl esters to total lipids ratio in medium VLDL 115,082 European ancestry individuals G 0.339706 3E-12 11.523 rs2618566 0.0284981 very low density lipoprotein cholesterol measurement (EFO:0008317)
cholesteryl esters:total lipids ratio (EFO:0020944)
 PMID:35213538
GWAS950681_H GCST006612 LDL cholesterol 215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals T 0.6491 9E-22 21.046 rs2618566 0.03 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:30275531
None Available GCST90093039 Triglycerides to total lipids ratio in very small VLDL 115,082 European ancestry individuals G 0.339706 3E-9 8.523 rs2618566 0.024514 triglycerides:total lipids ratio (EFO:0020947)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
None Available GCST90092809 Apolipoprotein B levels 115,082 European ancestry individuals G 0.339706 4E-8 7.398 rs2618566 0.0240134 apolipoprotein B measurement (EFO:0004615)
 PMID:35213538
None Available GCST90092814 Clinical LDL cholesterol levels 115,082 European ancestry individuals G 0.339706 9E-9 8.046 rs2618566 0.0249446 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
None Available GCST90093028 Cholesterol levels in very small VLDL 115,082 European ancestry individuals G 0.339706 4E-9 8.398 rs2618566 0.0249384 total cholesterol measurement (EFO:0004574)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
None Available GCST90092973 Free cholesterol to total lipids ratio in small VLDL 115,082 European ancestry individuals G 0.339706 8E-12 11.097 rs2618566 0.0283391 very low density lipoprotein cholesterol measurement (EFO:0008317)
free cholesterol:total lipids ratio (EFO:0020945)
 PMID:35213538
GWAS963029_H GCST90239655 Low density lipoprotein cholesterol levels 40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals ? NR 4E-153 152.398 rs2618566 N/A low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:34887591
GWAS963354_H GCST90092971 Cholesteryl esters to total lipids ratio in small VLDL 115,082 European ancestry individuals G 0.339706 7E-10 9.155 rs2618566 0.0264865 very low density lipoprotein cholesterol measurement (EFO:0008317)
cholesteryl esters:total lipids ratio (EFO:0020944)
 PMID:35213538
GWAS965720_H GCST90092960 Free cholesterol levels in small LDL 115,082 European ancestry individuals G 0.339706 2E-11 10.699 rs2618566 0.0293445 free cholesterol measurement (EFO:0008591)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
GWAS966440_H GCST90092964 Phospholipid levels in small LDL 115,082 European ancestry individuals G 0.339706 1E-11 11 rs2618566 0.0294292 low density lipoprotein cholesterol measurement (EFO:0004611)
phospholipid measurement (EFO:0004639)
 PMID:35213538
GWAS966446_H GCST90092969 Cholesterol to total lipids ratio in small VLDL 115,082 European ancestry individuals G 0.339706 4E-12 11.398 rs2618566 0.0293186 very low density lipoprotein cholesterol measurement (EFO:0008317)
cholesterol:total lipids ratio (EFO:0020943)
 PMID:35213538
None Available GCST90018961 LDL cholesterol 343,621 European ancestry individuals, 72,866 East Asian ancestry individuals T NR 2E-22 21.699 rs2618566 0.0219 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:34594039
None Available GCST90093027 Triglycerides to total lipids ratio in very large VLDL 114,160 European ancestry individuals G 0.339725 2E-10 9.699 rs2618566 0.0269519 triglycerides:total lipids ratio (EFO:0020947)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
GWAS973018_H GCST90239676 Total cholesterol levels 1,320,016 European ancestry individuals T 0.660697 6E-74 73.222 rs2618566 0.0317594 total cholesterol measurement (EFO:0004574)
 PMID:34887591
GWAS975849_H GCST90239658 Low density lipoprotein cholesterol levels 1,320,016 European ancestry individuals T 0.660959 5E-117 116.302 rs2618566 0.040212 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:34887591
GWAS978034_H GCST90239670 Non-HDL cholesterol levels 1,320,016 European ancestry individuals G 0.3369 7E-66 65.155 rs2618566 0.0353905 non-high density lipoprotein cholesterol measurement (EFO:0005689)
 PMID:34887591
GWAS980283_H GCST90093033 Free cholesterol to total lipids ratio in very small VLDL 115,082 European ancestry individuals G 0.339706 5E-9 8.302 rs2618566 0.0253474 very low density lipoprotein cholesterol measurement (EFO:0008317)
free cholesterol:total lipids ratio (EFO:0020945)
 PMID:35213538
None Available GCST90093021 Free cholesterol to total lipids ratio in very large VLDL 114,160 European ancestry individuals G 0.339725 1E-8 8 rs2618566 0.024008 very low density lipoprotein cholesterol measurement (EFO:0008317)
free cholesterol:total lipids ratio (EFO:0020945)
 PMID:35213538
None Available GCST90092977 Phospholipids to total lipids ratio in small VLDL 115,082 European ancestry individuals G 0.339706 2E-12 11.699 rs2618566 0.0291331 very low density lipoprotein cholesterol measurement (EFO:0008317)
phospholipids:total lipids ratio (EFO:0020946)
 PMID:35213538
None Available GCST90093030 Cholesteryl ester levels in very small VLDL 115,082 European ancestry individuals G 0.339706 2E-9 8.699 rs2618566 0.0253372 cholesteryl ester measurement (EFO:0010351)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
None Available GCST90092979 Triglycerides to total lipids ratio in small VLDL 115,082 European ancestry individuals G 0.339706 2E-12 11.699 rs2618566 0.0297089 triglycerides:total lipids ratio (EFO:0020947)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
GWAS982927_H GCST90239667 Non-HDL cholesterol levels 40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals ? NR 3E-85 84.523 rs2618566 N/A non-high density lipoprotein cholesterol measurement (EFO:0005689)
 PMID:34887591
GWAS994842_H GCST90239673 Total cholesterol levels 40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals ? NR 3E-98 97.523 rs2618566 N/A total cholesterol measurement (EFO:0004574)
 PMID:34887591
None Available GCST90018989 Medication use (HMG CoA reductase inhibitors) 73,475 European ancestry cases, 216,910 European ancestry controls, 33,295 East Asian ancestry cases, 145,431 East Asian ancestry controls T NR 2E-13 12.699 rs2618566 0.0377 HMG CoA reductase inhibitor use measurement (EFO:0009932)
 PMID:34594039
Database Acc Id Source(s)
GWAS Catalog GCST90092837 GWAS Catalog
  GCST90269622 GWAS Catalog
  GCST90302071 GWAS Catalog

RGD Curation Notes
Note Type Note Reference