GWAS759654_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS759654_H (phospholipids in VLDL measurement QTL GWAS759654 (human)) Homo sapiens

Symbol: GWAS759654_H
Name: phospholipids in VLDL measurement QTL GWAS759654 (human)
RGD ID: 407110678
Trait: phospholipids in VLDL measurement
LOD Score: Not Available
P Value: 4.0E-52
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh386160,330,499 - 160,330,500RGD_MAPPER_PIPELINEGRCh38
GRCh376160,751,531 - 160,751,532RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS759654_HHumanphospholipids in VLDL measurement  IAGPrs9295128405850206 GWAS_CATALOGPMID:36764567
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Position Markers

Peak: (rs9295128)
Human AssemblyChrPosition (strand)Source
GRCh386160,330,499 - 160,330,500RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407039808GWAS688784_Hphospholipids in small VLDL measurement QTL GWAS688784 (human)3e-21phospholipids in small VLDL measurementblood very low density lipoprotein phospholipid level (CMO:0001571)6160330499160330500Human
407033153GWAS682129_Htriglycerides in very small VLDL measurement QTL GWAS682129 (human)1e-25triglycerides in very small VLDL measurementblood very low density lipoprotein triglyceride level (CMO:0002688)6160330499160330500Human
407039425GWAS688401_Hphospholipids in medium VLDL measurement QTL GWAS688401 (human)4e-29phospholipids in medium VLDL measurementblood very low density lipoprotein phospholipid level (CMO:0001571)6160330499160330500Human
407033540GWAS682516_Hcholesterol in large VLDL measurement QTL GWAS682516 (human)9e-50cholesterol in large VLDL measurement 6160330499160330500Human
407100357GWAS749333_Hphospholipids:total lipids ratio QTL GWAS749333 (human)2e-13phospholipids:total lipids ratio6160330499160330500Human
407029893GWAS678869_Hvery low density lipoprotein cholesterol measurement QTL GWAS678869 (human)1e-32very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)6160330499160330500Human
407037322GWAS686298_Hcholesteryl ester measurement QTL GWAS686298 (human)3e-14blood lipid amount (VT:0003949)6160330499160330500Human
407231117GWAS880093_Hlipoprotein-associated phospholipase A(2) measurement QTL GWAS880093 (human)4e-11lipoprotein-associated phospholipase A(2) measurement6160330499160330500Human
407040338GWAS689314_Hpolyunsaturated fatty acid measurement QTL GWAS689314 (human)7e-29milk polyunsaturated fatty acid amount (VT:0010374)milk polyunsaturated fatty acid measurement (CMO:0000821)6160330499160330500Human
407118292GWAS767268_Htriglycerides in IDL measurement QTL GWAS767268 (human)9e-16triglycerides in IDL measurementblood lipoprotein triglyceride level (CMO:0002685)6160330499160330500Human
407037587GWAS686563_Hcholesteryl ester measurement QTL GWAS686563 (human)3e-22blood lipid amount (VT:0003949)6160330499160330500Human
407110678GWAS759654_Hphospholipids in VLDL measurement QTL GWAS759654 (human)4e-52phospholipids in VLDL measurement 6160330499160330500Human
1643404BMD3_HBone mineral density QTL 3 (human)2.420.0005Bone mineral density6157563614170805979Human
407035354GWAS684330_Hcholesteryl ester measurement QTL GWAS684330 (human)1e-39blood lipid amount (VT:0003949)6160330499160330500Human
407038554GWAS687530_Hfree cholesterol in medium VLDL measurement QTL GWAS687530 (human)4e-21free cholesterol in medium VLDL measurement 6160330499160330500Human
407037528GWAS686504_Hcholesteryl ester measurement QTL GWAS686504 (human)5e-15blood lipid amount (VT:0003949)6160330499160330500Human
407033438GWAS682414_Hcholesteryl ester measurement QTL GWAS682414 (human)2e-48blood lipid amount (VT:0003949)6160330499160330500Human
407067039GWAS716015_Hparental longevity QTL GWAS716015 (human)2e-11parental longevity6160330499160330500Human
407032159GWAS681135_Hfree cholesterol in VLDL measurement QTL GWAS681135 (human)2e-46free cholesterol in VLDL measurement 6160330499160330500Human
407041120GWAS690096_Hlow density lipoprotein cholesterol measurement QTL GWAS690096 (human)3e-15agingblood low density lipoprotein cholesterol level (CMO:0000053)6160330499160330500Human
407040672GWAS689648_Htotal lipids in small VLDL QTL GWAS689648 (human)9e-32total lipids in small VLDL6160330499160330500Human
407024353GWAS673329_Hcholesteryl esters to total lipids in large LDL percentage QTL GWAS673329 (human)2e-17cholesteryl esters to total lipids in large LDL percentage 6160330499160330500Human
407036455GWAS685431_Hcholesterol in small VLDL measurement QTL GWAS685431 (human)8e-14cholesterol in small VLDL measurement 6160330499160330500Human
407029477GWAS678453_Hlinoleic acid measurement QTL GWAS678453 (human)1e-29linoleic acid measurementblood free fatty acids level (CMO:0000117)6160330499160330500Human
407029355GWAS678331_Homega-6 polyunsaturated fatty acid measurement QTL GWAS678331 (human)2e-26omega-6 polyunsaturated fatty acid measurement6160330499160330500Human
407037224GWAS686200_Htotal lipids in small LDL QTL GWAS686200 (human)9e-13total lipids in small LDL6160330499160330500Human
407035566GWAS684542_Hcholesteryl ester measurement QTL GWAS684542 (human)2e-19blood lipid amount (VT:0003949)blood low density lipoprotein cholesterol level (CMO:0000053)6160330499160330500Human
407040303GWAS689279_Htotal lipids in lipoprotein particles measurement QTL GWAS689279 (human)1e-24total lipids in lipoprotein particles measurement 6160330499160330500Human
407033772GWAS682748_Hvery low density lipoprotein cholesterol measurement QTL GWAS682748 (human)4e-32very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)6160330499160330500Human
407029818GWAS678794_Homega-3 polyunsaturated fatty acid measurement QTL GWAS678794 (human)4e-14omega-3 polyunsaturated fatty acid measurement6160330499160330500Human
407041854GWAS690830_Htriglycerides in large LDL measurement QTL GWAS690830 (human)1e-15triglycerides in large LDL measurement 6160330499160330500Human
1643367BW323_HBody weight QTL 323 (human)2.420.0005Body fat amount6157563614170805979Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS673329_H GCST90269713 Cholesteryl esters to total lipids in large LDL percentage (UKB data field 23616) 88,329 European ancestry individuals T 0.0167942 2E-17 16.699 rs9295128 0.159131 cholesteryl esters to total lipids in large LDL percentage (EFO:0022249)
 PMID:36764567
GWAS678331_H GCST90269542 Omega-6 fatty acids levels (UKB data field 23445) 88,268 European ancestry individuals T 0.0168058 2E-26 25.699 rs9295128 0.195014 omega-6 polyunsaturated fatty acid measurement (EFO:0005680)
 PMID:36764567
GWAS678453_H GCST90269546 Linoleic acid levels (UKB data field 23449) 88,268 European ancestry individuals T 0.0168058 1E-29 29 rs9295128 0.207494 linoleic acid measurement (EFO:0006807)
 PMID:36764567
GWAS678794_H GCST90269541 Omega-3 fatty acids levels (UKB data field 23444) 88,268 European ancestry individuals T 0.0168058 4E-14 13.398 rs9295128 0.137062 omega-3 polyunsaturated fatty acid measurement (EFO:0010119)
 PMID:36764567
GWAS678869_H GCST90269525 Concentration of VLDL particles (UKB data field 23428) 88,329 European ancestry individuals T 0.0167942 1E-32 32 rs9295128 0.222387 very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:36764567
GWAS681135_H GCST90269517 Free cholesterol in VLDL (UKB data field 23420) 88,329 European ancestry individuals T 0.0167942 2E-46 45.699 rs9295128 0.266545 free cholesterol in VLDL measurement (EFO:0022276)
 PMID:36764567
GWAS682129_H GCST90269619 Triglycerides in very small VLDL (UKB data field 23522) 88,329 European ancestry individuals T 0.0167942 1E-25 25 rs9295128 0.192937 triglycerides in very small VLDL measurement (EFO:0022144)
 PMID:36764567
GWAS682414_H GCST90269589 Cholesteryl esters in very large VLDL (UKB data field 23492) 88,329 European ancestry individuals T 0.0167942 2E-48 47.699 rs9295128 0.270995 cholesteryl ester measurement (EFO:0010351)
 PMID:36764567
GWAS682516_H GCST90269595 Cholesterol in large VLDL (UKB data field 23498) 88,329 European ancestry individuals T 0.0167942 9E-50 49.046 rs9295128 0.272972 cholesterol in large VLDL measurement (EFO:0021902)
 PMID:36764567
GWAS682748_H GCST90269500 VLDL cholesterol levels (UKB data field 23403) 88,329 European ancestry individuals T 0.0167942 4E-32 31.398 rs9295128 0.221255 very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:36764567
GWAS684330_H GCST90269596 Cholesteryl esters in large VLDL (UKB data field 23499) 88,329 European ancestry individuals T 0.0167942 1E-39 39 rs9295128 0.24454 cholesteryl ester measurement (EFO:0010351)
 PMID:36764567
GWAS684542_H GCST90269645 Cholesteryl esters in small LDL (UKB data field 23548) 88,329 European ancestry individuals T 0.0167942 2E-19 18.699 rs9295128 0.169932 cholesteryl ester measurement (EFO:0010351)
 PMID:36764567
GWAS685431_H GCST90269609 Cholesterol in small VLDL (UKB data field 23512) 88,329 European ancestry individuals T 0.0167942 8E-14 13.097 rs9295128 0.140303 cholesterol in small VLDL measurement (EFO:0022228)
 PMID:36764567
GWAS686200_H GCST90269642 Total lipids in small LDL (UKB data field 23545) 88,329 European ancestry individuals T 0.0167942 9E-13 12.046 rs9295128 0.134337 total lipids in small LDL (EFO:0022168)
 PMID:36764567
GWAS686298_H GCST90269610 Cholesteryl esters in small VLDL (UKB data field 23513) 88,329 European ancestry individuals T 0.0167942 3E-14 13.523 rs9295128 0.142343 cholesteryl ester measurement (EFO:0010351)
 PMID:36764567
GWAS686504_H GCST90269638 Cholesteryl esters in medium LDL (UKB data field 23541) 88,329 European ancestry individuals T 0.0167942 5E-15 14.302 rs9295128 0.147579 cholesteryl ester measurement (EFO:0010351)
 PMID:36764567
GWAS686563_H GCST90269513 Cholesteryl esters in VLDL (UKB data field 23416) 88,329 European ancestry individuals T 0.0167942 3E-22 21.523 rs9295128 0.182549 cholesteryl ester measurement (EFO:0010351)
 PMID:36764567
None Available GCST90269641 Concentration of small LDL particles (UKB data field 23544) 88,329 European ancestry individuals T 0.0167942 2E-19 18.699 rs9295128 0.169825 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:36764567
GWAS687530_H GCST90269604 Free cholesterol in medium VLDL (UKB data field 23507) 88,329 European ancestry individuals T 0.0167942 4E-21 20.398 rs9295128 0.177102 free cholesterol in medium VLDL measurement (EFO:0022269)
 PMID:36764567
None Available GCST90269599 Concentration of medium VLDL particles (UKB data field 23502) 88,329 European ancestry individuals T 0.0167942 1E-32 32 rs9295128 0.223083 very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:36764567
GWAS688401_H GCST90269601 Phospholipids in medium VLDL (UKB data field 23504) 88,329 European ancestry individuals T 0.0167942 4E-29 28.398 rs9295128 0.210287 phospholipids in medium VLDL measurement (EFO:0022154)
 PMID:36764567
GWAS688784_H GCST90269608 Phospholipids in small VLDL (UKB data field 23511) 88,329 European ancestry individuals T 0.0167942 3E-21 20.523 rs9295128 0.177767 phospholipids in small VLDL measurement (EFO:0022146)
 PMID:36764567
GWAS689279_H GCST90269520 Total lipids in lipoprotein particles (UKB data field 23423) 88,329 European ancestry individuals T 0.0167942 1E-24 24 rs9295128 0.189439 total lipids in lipoprotein particles measurement (EFO:0022309)
 PMID:36764567
GWAS689314_H GCST90269543 Polyunsaturated fatty acids levels (UKB data field 23446) 88,268 European ancestry individuals T 0.0168058 7E-29 28.155 rs9295128 0.203689 polyunsaturated fatty acid measurement (EFO:0010733)
 PMID:36764567
GWAS689648_H GCST90269607 Total lipids in small VLDL (UKB data field 23510) 88,329 European ancestry individuals T 0.0167942 9E-32 31.046 rs9295128 0.218083 total lipids in small VLDL (EFO:0022148)
 PMID:36764567
None Available GCST90269600 Total lipids in medium VLDL (UKB data field 23503) 88,329 European ancestry individuals T 0.0167942 1E-39 39 rs9295128 0.2457 total lipids in medium VLDL (EFO:0022153)
 PMID:36764567
None Available GCST90269606 Concentration of small VLDL particles (UKB data field 23509) 88,329 European ancestry individuals T 0.0167942 1E-32 32 rs9295128 0.220785 very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:36764567
GWAS690096_H GCST90269634 Concentration of medium LDL particles (UKB data field 23537) 88,329 European ancestry individuals T 0.0167942 3E-15 14.523 rs9295128 0.148682 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:36764567
GWAS690830_H GCST90269633 Triglycerides in large LDL (UKB data field 23536) 88,329 European ancestry individuals T 0.0167942 1E-15 15 rs9295128 0.147671 triglycerides in large LDL measurement (EFO:0022319)
 PMID:36764567
GWAS716015_H GCST006697 Parental longevity (combined parental attained age, Martingale residuals) 389,166 British ancestry individuals G 0.983087 2E-11 10.699 rs9295128 0.0594745 parental longevity (EFO:0007796)
 PMID:29227965
GWAS749333_H GCST90269711 Phospholipids to total lipids in large LDL percentage (UKB data field 23614) 88,329 European ancestry individuals T 0.0167942 2E-13 12.699 rs9295128 0.137132 phospholipids:total lipids ratio (EFO:0020946)
 PMID:36764567
GWAS759654_H GCST90269509 Phospholipids in VLDL (UKB data field 23412) 88,329 European ancestry individuals T 0.0167942 4E-52 51.398 rs9295128 0.281735 phospholipids in VLDL measurement (EFO:0022301)
 PMID:36764567
GWAS767268_H GCST90269626 Triglycerides in IDL (UKB data field 23529) 88,329 European ancestry individuals T 0.0167942 9E-16 15.046 rs9295128 0.148055 triglycerides in IDL measurement (EFO:0022149)
 PMID:36764567
None Available GCST90321079 Aging 1,559,001 European ancestry individuals G NR 3E-15 14.523 rs9295128 0.037662756 aging (EFO:0022597)
 PMID:37550455
GWAS880093_H GCST004963 Lipoprotein phospholipase A2 activity in cardiovascular disease 22,156 European, Asian, African, Arabic, Native American, Pacific Islander and other ancestry T 0.01694 4E-11 10.398 rs9295128 11.72 lipoprotein-associated phospholipase A(2) measurement (EFO:0004746)
 PMID:28753643
Database Acc Id Source(s)
GWAS Catalog GCST90269509 GWAS Catalog

RGD Curation Notes
Note Type Note Reference