GWAS755916_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS755916_H (very low density lipoprotein cholesterol measurement, lipid measurement QTL GWAS755916 (human)) Homo sapiens

Symbol: GWAS755916_H
Name: very low density lipoprotein cholesterol measurement, lipid measurement QTL GWAS755916 (human)
RGD ID: 407106940
Trait: very low density lipoprotein cholesterol measurement, lipid measurement
Measurement Type: blood lipid measurement   (CMO:0000050)    
blood triglyceride level   (CMO:0000118)    
blood very low density lipoprotein cholesterol level   (CMO:0000648)    
LOD Score: Not Available
P Value: 3.0E-10
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381944,912,921 - 44,912,922RGD_MAPPER_PIPELINEGRCh38
GRCh371945,416,178 - 45,416,179RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS755916_HHumanblood lipid measurement  IAGPrs483082405850206Based on the EFO term IDGWAS_CATALOGPMID:34610981
GWAS755916_HHumanblood triglyceride level  IAGPrs483082405850206Based on the EFO term IDGWAS_CATALOGPMID:30718733
GWAS755916_HHumanblood very low density lipoprotein cholesterol level  IAGPrs483082405850206Based on the EFO term IDGWAS_CATALOGPMID:34610981

Experimental Factor Annotations    Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
155765829LOC127891702H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:45415901-45416660194491264444913403Human

Position Markers

Peak: (rs483082)
Human AssemblyChrPosition (strand)Source
GRCh381944,912,921 - 44,912,922RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407185093GWAS834069_Hprotein measurement QTL GWAS834069 (human)2e-605protein measurement194491292144912922Human
407354055GWAS1003031_Hglutathione S-transferase Mu 1 measurement QTL GWAS1003031 (human)4e-21glutathione S-transferase Mu 1 measurement194491292144912922Human
407179588GWAS828564_Htriglyceride measurement QTL GWAS828564 (human)1e-477triglyceride measurementblood triglyceride level (CMO:0000118)194491292144912922Human
407221316GWAS870292_Htriglycerides in very large HDL measurement QTL GWAS870292 (human)2e-46triglycerides in very large HDL measurement 194491292144912922Human
407368128GWAS1017104_Hsphingomyelin measurement QTL GWAS1017104 (human)2e-112-palmitoyl-GPE (16:0) measurement194491292144912922Human
407369920GWAS1018896_Hblood protein measurement QTL GWAS1018896 (human)4e-89blood protein measurementblood protein measurement (CMO:0000028)194491292144912922Human
407114444GWAS763420_Hlinoleic acid measurement QTL GWAS763420 (human)2e-09linoleic acid measurementblood free fatty acids level (CMO:0000117)194491292144912922Human
407383108GWAS1032084_Htriglyceride measurement QTL GWAS1032084 (human)6e-787triglyceride measurementblood triglyceride level (CMO:0000118)194491292144912922Human
407086670GWAS735646_Hmetabolic syndrome QTL GWAS735646 (human)2e-32metabolic syndrome194491292144912922Human
407369417GWAS1018393_Hblood protein measurement QTL GWAS1018393 (human)6e-38blood protein measurementblood protein measurement (CMO:0000028)194491292144912922Human
407354313GWAS1003289_Hsex hormone-binding globulin measurement QTL GWAS1003289 (human)7e-15sex hormone-binding globulin measurement194491292144912922Human
407354568GWAS1003544_Hlipoprotein A measurement QTL GWAS1003544 (human)6e-46lipoprotein A measurement194491292144912922Human
407112020GWAS760996_Hapolipoprotein B measurement QTL GWAS760996 (human)2e-12apolipoprotein B measurementblood apoliprotein B level (CMO:0000522)194491292144912922Human
407369174GWAS1018150_Hblood protein measurement QTL GWAS1018150 (human)2e-91blood protein measurementblood protein measurement (CMO:0000028)194491292144912922Human
407209428GWAS858404_Hneuronal pentraxin-2 measurement QTL GWAS858404 (human)1e-31neuronal pentraxin-2 measurement194491292144912922Human
407113558GWAS762534_Hremnant cholesterol measurement QTL GWAS762534 (human)6e-11remnant cholesterol measurement194491292144912922Human
407353173GWAS1002149_Hvery low density lipoprotein cholesterol measurement QTL GWAS1002149 (human)3e-23very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)194491292144912922Human
407077079GWAS726055_Htriglyceride measurement QTL GWAS726055 (human)1e-292triglyceride measurementblood triglyceride level (CMO:0000118)194491292144912922Human
407328721GWAS977697_Hsex hormone-binding globulin measurement QTL GWAS977697 (human)2e-21total cholesterol measurementblood total cholesterol level (CMO:0000051)194491292144912922Human
407378257GWAS1027233_Hapolipoprotein B measurement QTL GWAS1027233 (human)6e-125apolipoprotein B measurementblood apoliprotein B level (CMO:0000522)194491292144912922Human
407265370GWAS914346_HAlzheimer disease QTL GWAS914346 (human)1e-37Alzheimer disease194491292144912922Human
407177048GWAS826024_Htriglyceride measurement QTL GWAS826024 (human)4e-49triglyceride measurementblood triglyceride level (CMO:0000118)194491292144912922Human
407265371GWAS914347_HAlzheimer disease QTL GWAS914347 (human)1e-62Alzheimer disease194491292144912922Human
407114213GWAS763189_Hpolyunsaturated fatty acid measurement QTL GWAS763189 (human)5e-14milk polyunsaturated fatty acid amount (VT:0010374)milk polyunsaturated fatty acid measurement (CMO:0000821)194491292144912922Human
407090658GWAS739634_Htriglyceride measurement QTL GWAS739634 (human)1e-195triglyceride measurementblood triglyceride level (CMO:0000118)194491292144912922Human
407352931GWAS1001907_Hvery low density lipoprotein cholesterol measurement, phospholipid measurement QTL GWAS1001907 (human)2e-23very low density lipoprotein cholesterol measurement, phospholipid measurementblood very low density lipoprotein cholesterol level (CMO:0000648)194491292144912922Human
407355502GWAS1004478_Hsexual dimorphism measurement QTL GWAS1004478 (human)9e-39sexual dimorphism measurement194491292144912922Human
407106925GWAS755901_Hvery low density lipoprotein cholesterol measurement, esterified cholesterol measurement QTL GWAS755901 (human)1e-08very low density lipoprotein cholesterol measurement, esterified cholesterol measurementblood lipid measurement (CMO:0000050)194491292144912922Human
407375718GWAS1024694_Hdiacylglycerol 36:3 measurement QTL GWAS1024694 (human)4e-10diacylglycerol 36:4 measurement194491292144912922Human
407354729GWAS1003705_Htriglyceride:HDL cholesterol ratio QTL GWAS1003705 (human)3e-57triglyceride:HDL cholesterol ratio194491292144912922Human
407357800GWAS1006776_Hcomplex trait QTL GWAS1006776 (human)2e-19complex trait194491292144912922Human
407365491GWAS1014467_Haspartate aminotransferase to alanine aminotransferase ratio QTL GWAS1014467 (human)1e-47aspartate aminotransferase to alanine aminotransferase ratioserum aspartate aminotransferase activity level to alanine aminotransferase activity level ratio (CMO:0002245)194491292144912922Human
407336946GWAS985922_Htriglyceride measurement QTL GWAS985922 (human)1e-85triglyceride measurementblood triglyceride level (CMO:0000118)194491292144912922Human
407188978GWAS837954_Hapolipoprotein E measurement QTL GWAS837954 (human)7e-109apolipoprotein E measurement194491292144912922Human
407108212GWAS757188_Hlinoleic acid measurement QTL GWAS757188 (human)5e-16linoleic acid measurementblood free fatty acids level (CMO:0000117)194491292144912922Human
407369342GWAS1018318_Hblood protein measurement QTL GWAS1018318 (human)8e-162blood protein measurementblood protein measurement (CMO:0000028)194491292144912922Human
407106940GWAS755916_Hvery low density lipoprotein cholesterol measurement, lipid measurement QTL GWAS755916 (human)3e-10triglyceride measurementblood triglyceride level (CMO:0000118)194491292144912922Human
407376887GWAS1025863_Hdiglyceride measurement QTL GWAS1025863 (human)6e-12diglyceride measurement194491292144912922Human
407192325GWAS841301_Hprotein measurement QTL GWAS841301 (human)5e-18protein measurement194491292144912922Human
407114244GWAS763220_Hapolipoprotein B measurement QTL GWAS763220 (human)7e-09remnant cholesterol measurementblood apoliprotein B level (CMO:0000522)194491292144912922Human
407394954GWAS1043930_Hcirrhosis of liver QTL GWAS1043930 (human)3e-14cirrhosis of liver194491292144912922Human
407372938GWAS1021914_Hserum alanine aminotransferase measurement QTL GWAS1021914 (human)1e-19serum alanine aminotransferase measurementserum alanine aminotransferase activity level (CMO:0000575)194491292144912922Human
407329284GWAS978260_Hsex hormone-binding globulin measurement QTL GWAS978260 (human)1e-23amyloid-beta measurement194491292144912922Human
407397131GWAS1046107_Hlinoleoyl-arachidonoyl-glycerol (18:2/20:4) [2] measurement QTL GWAS1046107 (human)3e-12linoleoyl-arachidonoyl-glycerol (18:2/20:4) [2] measurement194491292144912922Human
407377164GWAS1026140_Hdiacylglycerol 38:5 measurement QTL GWAS1026140 (human)6e-16diacylglycerol 38:5 measurement194491292144912922Human
407369345GWAS1018321_Hblood protein measurement QTL GWAS1018321 (human)3e-26blood protein measurementblood protein measurement (CMO:0000028)194491292144912922Human
407368449GWAS1017425_Htriglyceride measurement QTL GWAS1017425 (human)1e-11triglyceride measurementblood triglyceride level (CMO:0000118)194491292144912922Human
406929159GWAS578135_HAlzheimer disease QTL GWAS578135 (human)1e-15Alzheimer disease194491292144912922Human
407353609GWAS1002585_Htriglyceride:HDL cholesterol ratio QTL GWAS1002585 (human)5e-192triglyceride:HDL cholesterol ratio194491292144912922Human
1559110SCL22_HSerum cholesterol level QTL 22 (human)3.590.000241Lipid levelLDL cholesterol193190759457907594Human
407114256GWAS763232_Hvery low density lipoprotein cholesterol measurement, esterified cholesterol measurement QTL GWAS763232 (human)3e-08very low density lipoprotein cholesterol measurement, lipid measurementblood lipid measurement (CMO:0000050)194491292144912922Human
407370130GWAS1019106_Hblood protein measurement QTL GWAS1019106 (human)5e-34blood protein measurementblood protein measurement (CMO:0000028)194491292144912922Human
407369375GWAS1018351_Hblood protein measurement QTL GWAS1018351 (human)5e-43blood protein measurementblood protein measurement (CMO:0000028)194491292144912922Human
407364639GWAS1013615_Hsphingomyelin measurement QTL GWAS1013615 (human)3e-11sphingomyelin measurement194491292144912922Human
1331657COPD9_HChronic obstructive pulmonary disease QTL 9 (human)1.94Chronic airflow obstructionpost-bronchodilator FEV1193102176057021760Human
407184408GWAS833384_Htriglyceride measurement QTL GWAS833384 (human)7e-129blood protein measurementblood protein measurement (CMO:0000028)194491292144912922Human
407114265GWAS763241_Hvery low density lipoprotein cholesterol measurement, esterified cholesterol measurement QTL GWAS763241 (human)3e-13oleoyl-linoleoyl-glycerol (18:1/18:2) [2] measurementblood very low density lipoprotein cholesterol level (CMO:0000648)194491292144912922Human
407369240GWAS1018216_Hblood protein measurement QTL GWAS1018216 (human)1e-100blood protein measurementblood protein measurement (CMO:0000028)194491292144912922Human
407351832GWAS1000808_Htriglyceride measurement, intermediate density lipoprotein measurement QTL GWAS1000808 (human)4e-31triglyceride measurement, intermediate density lipoprotein measurementblood intermediate density lipoprotein cholesterol level (CMO:0001562)194491292144912922Human
407370023GWAS1018999_Hblood protein measurement QTL GWAS1018999 (human)2e-113blood protein measurementblood protein measurement (CMO:0000028)194491292144912922Human
407368869GWAS1017845_Hblood protein measurement QTL GWAS1017845 (human)2e-25blood protein measurementblood protein measurement (CMO:0000028)194491292144912922Human
407252261GWAS901237_Hlinoleoyl-arachidonoyl-glycerol (18:2/20:4) [2] measurement QTL GWAS901237 (human)8e-22linoleoyl-arachidonoyl-glycerol (18:2/20:4) [2] measurement194491292144912922Human
407353763GWAS1002739_Hhigh density lipoprotein cholesterol measurement QTL GWAS1002739 (human)8e-21high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)194491292144912922Human
407357986GWAS1006962_Htriglyceride measurement, phospholipid measurement QTL GWAS1006962 (human)2e-104triglyceride measurement, phospholipid measurementblood triglyceride level (CMO:0000118)194491292144912922Human
407392175GWAS1041151_Hcirrhosis of liver QTL GWAS1041151 (human)9e-14cirrhosis of liver194491292144912922Human
407310255GWAS959231_Hcerebral amyloid deposition measurement QTL GWAS959231 (human)1e-13cerebral cortex integrity trait (VT:0010923)194491292144912922Human
407353774GWAS1002750_Htriglyceride measurement QTL GWAS1002750 (human)2e-219triglyceride measurementblood triglyceride level (CMO:0000118)194491292144912922Human
407354158GWAS1003134_Htriglyceride:HDL cholesterol ratio QTL GWAS1003134 (human)9e-168triglyceride:HDL cholesterol ratio194491292144912922Human
407369260GWAS1018236_Hblood protein measurement QTL GWAS1018236 (human)6e-261blood protein measurementblood protein measurement (CMO:0000028)194491292144912922Human
407118889GWAS767865_Homega-6 polyunsaturated fatty acid measurement QTL GWAS767865 (human)1e-101-stearoyl-2-linoleoyl-GPE (18:0/18:2) measurement194491292144912922Human
407395238GWAS1044214_Holeoyl-arachidonoyl-glycerol (18:1/20:4) [2] measurement QTL GWAS1044214 (human)4e-14oleoyl-arachidonoyl-glycerol (18:1/20:4) [2] measurement194491292144912922Human
407367208GWAS1016184_HC-reactive protein measurement QTL GWAS1016184 (human)3e-579C-reactive protein measurementblood C-reactive protein level (CMO:0003160)194491292144912922Human
407187638GWAS836614_Hbeta-1,3-N-acetylglucosaminyltransferase radical fringe measurement QTL GWAS836614 (human)6e-41beta-1,3-N-acetylglucosaminyltransferase radical fringe measurement194491292144912922Human
407119671GWAS768647_Hpolyunsaturated fatty acid measurement QTL GWAS768647 (human)3e-09milk polyunsaturated fatty acid amount (VT:0010374)milk polyunsaturated fatty acid measurement (CMO:0000821)194491292144912922Human
407352370GWAS1001346_Hlow density lipoprotein cholesterol measurement QTL GWAS1001346 (human)2e-78low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)194491292144912922Human
407381438GWAS1030414_H1-palmitoyl-GPE (16:0) measurement QTL GWAS1030414 (human)2e-151-palmitoyl-GPE (16:0) measurement194491292144912922Human
407379504GWAS1028480_Htriglyceride measurement QTL GWAS1028480 (human)9e-73triglyceride measurementblood triglyceride level (CMO:0000118)194491292144912922Human
407379122GWAS1028098_Hapolipoprotein A 1 measurement QTL GWAS1028098 (human)5e-19apolipoprotein A 1 measurementblood apolipoprotein AI level (CMO:0000520)194491292144912922Human
407354172GWAS1003148_Htriglyceride measurement, low density lipoprotein cholesterol measurement QTL GWAS1003148 (human)1e-52triglyceride measurement, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)194491292144912922Human
407351227GWAS1000203_Htriglyceride measurement QTL GWAS1000203 (human)8e-10triglyceride measurementblood triglyceride level (CMO:0000118)194491292144912922Human
407369912GWAS1018888_Hblood protein measurement QTL GWAS1018888 (human)2e-156blood protein measurementblood protein measurement (CMO:0000028)194491292144912922Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS578135_H GCST004246 Alzheimer's disease 13,100 European ancestry cases, 13,220 European ancestry controls, 1,472 African American cases, 3,511 African American controls, 951 Japanese ancestry cases, 894 Japanese ancestry controls, 51 Israeli-Arab ancestry cases, 64 Israeli-Arab ancestry controls T NR 1E-15 15 rs483082 2.8 PMID:28183528
GWAS726055_H GCST010244 Triglyceride levels 441,016 European ancestry individuals G 0.764648 1E-292 292 rs483082 0.0858847 triglyceride measurement (EFO:0004530)
 PMID:32203549
GWAS735646_H GCST009602 Metabolic syndrome 291,107 European ancestry individuals T 0.238624 2E-32 31.699 rs483082 0.0899299 metabolic syndrome (EFO:0000195)
 PMID:31589552
GWAS739634_H GCST010173 Triglyceride levels 324,694 British ancestry individuals ? NR 1E-195 195 rs483082 0.0919 triglyceride measurement (EFO:0004530)
 PMID:32154731
GWAS826024_H GCST90239663 Triglyceride levels 146,492 East Asian ancestry individuals T 0.166411 4E-49 48.398 rs483082 0.112978 triglyceride measurement (EFO:0004530)
 PMID:34887591
GWAS828564_H GCST90239664 Triglyceride levels 1,320,016 European ancestry individuals T 0.229369 1E-477 477 rs483082 0.0960549 triglyceride measurement (EFO:0004530)
 PMID:34887591
GWAS833384_H GCST90179149 Triglyceride levels (MTAG) 361,194 European ancestry individuals T NR 7E-129 128.155 rs483082 0.070356 triglyceride measurement (EFO:0004530)
 PMID:36376304
GWAS834069_H GCST90246574 ADP-ribosylation factor-like protein 2 levels 10,708 European ancestry individuals T 0.24 2E-605 604.699 rs483082 0.748 protein measurement (EFO:0004747)
 PMID:34648354
GWAS836614_H GCST90249288 Beta-1,3-N-acetylglucosaminyltransferase radical fringe levels 10,708 European ancestry individuals T 0.24 6E-41 40.222 rs483082 0.216 beta-1,3-N-acetylglucosaminyltransferase radical fringe measurement (EFO:0801408)
 PMID:34648354
GWAS837954_H GCST90246550 Apolipoprotein E levels 10,708 European ancestry individuals T 0.24 7E-109 108.155 rs483082 0.348 apolipoprotein E measurement (EFO:0008029)
 PMID:34648354
GWAS841301_H GCST90248900 Prenylcysteine oxidase 1 levels 10,708 European ancestry individuals T 0.24 5E-18 17.302 rs483082 0.14 protein measurement (EFO:0004747)
 PMID:34648354
None Available GCST90435481 Triglyceride to HDL cholesterol ratio 382,129 individuals T 0.236 5E-172 171.302 rs483082 0.077 triglyceride:HDL cholesterol ratio (EFO:0007929)
 PMID:39277575
GWAS858404_H GCST90248721 Neuronal pentraxin-2 levels 10,708 European ancestry individuals T 0.24 1E-31 31 rs483082 0.179 neuronal pentraxin-2 measurement (EFO:0801834)
 PMID:34648354
None Available GCST90199914 Oleoyl-linoleoyl-glycerol (18:1/18:2) [2] levels 8,069 European ancestry individuals T 0.224256 3E-13 12.523 rs483082 0.136317 oleoyl-linoleoyl-glycerol (18:1/18:2) [2] measurement (EFO:0800333)
 PMID:36635386
GWAS870292_H GCST90269654 Triglycerides in very large HDL (UKB data field 23557) 88,329 European ancestry individuals T 0.236789 2E-46 45.699 rs483082 0.0779235 triglycerides in very large HDL measurement (EFO:0022324)
 PMID:36764567
GWAS901237_H GCST90200109 Linoleoyl-arachidonoyl-glycerol (18:2/20:4) [2] levels 7,744 European ancestry individuals T 0.224952 8E-22 21.097 rs483082 0.181667 linoleoyl-arachidonoyl-glycerol (18:2/20:4) [2] measurement (EFO:0800500)
 PMID:36635386
None Available GCST90200039 1-stearoyl-2-linoleoyl-GPE (18:0/18:2) levels 8,241 European ancestry individuals T 0.2237 1E-10 10 rs483082 0.11812 1-stearoyl-2-linoleoyl-GPE (18:0/18:2) measurement (EFO:0800402)
 PMID:36635386
None Available GCST007437 Triglyceride levels 6,949 Korean ancestry individuals T 0.169 3E-10 9.523 rs483082 0.0706 triglyceride measurement (EFO:0004530)
 PMID:30718733
GWAS914346_H GCST007600 Alzheimer's disease 952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls ? 0.734105 1E-37 37 rs483082 2.6149259 PMID:30636644
GWAS914347_H GCST007600 Alzheimer's disease 952 European ancestry male cases, 1,789 European ancestry female cases, 6,337 European ancestry male controls, 8,402 European ancestry female controls ? 0.738441 1E-62 62 rs483082 2.6436493 PMID:30636644
GWAS959231_H GCST006904 Cerebral amyloid deposition (PET imaging) 983 European ancestry individuals T 0.29 1E-13 13 rs483082 0.11 cerebral amyloid deposition measurement (EFO:0007707)
 PMID:30361487
GWAS977697_H GCST90012110 Sex hormone-binding globulin levels adjusted for BMI 368,929 European ancestry individuals T 0.23680500000000004 2E-21 20.699 rs483082 0.00934497 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:32042192
GWAS978260_H GCST90012111 Sex hormone-binding globulin levels 370,125 European ancestry individuals T 0.23680500000000004 1E-23 23 rs483082 0.010976 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:32042192
GWAS985922_H GCST011345 Triglyceride levels 76,081 European ancestry individuals, 127,395 Japanese ancestry individuals ? NR 1E-85 85 rs483082 0.0948 triglyceride measurement (EFO:0004530)
 PMID:33339817
GWAS1000203_H GCST90093142 Triglyceride levels 9,183 European ancestry individuals T NR 8E-10 9.097 rs483082 7.164 triglyceride measurement (EFO:0004530)
 PMID:33763119
GWAS1000808_H GCST90092841 Triglyceride levels in IDL 115,082 European ancestry individuals G 0.763461 4E-31 30.398 rs483082 0.0551132 triglyceride measurement (EFO:0004530)
intermediate density lipoprotein measurement (EFO:0008595)
 PMID:35213538
GWAS1001346_H GCST90019512 Low density lipoprotein cholesterol levels 341,875 European ancestry individuals, 6,003 African ancestry individuals, 7,319 South Asian ancestry individuals T NR 2E-78 77.699 rs483082 0.0555 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:33462484
GWAS1001907_H GCST90093024 Phospholipid levels in very large VLDL 115,082 European ancestry individuals G 0.763461 2E-23 22.699 rs483082 0.0466782 very low density lipoprotein cholesterol measurement (EFO:0008317)
phospholipid measurement (EFO:0004639)
 PMID:35213538
GWAS1002149_H GCST90093023 Concentration of very large VLDL particles 115,082 European ancestry individuals G 0.763461 3E-23 22.523 rs483082 0.0463565 very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
GWAS1002585_H GCST90295949 Triglyceride to HDL cholesterol ratio 402,398 European ancestry individuals T 0.2359 5E-192 191.302 rs483082 0.1095 triglyceride:HDL cholesterol ratio (EFO:0007929)
 PMID:38200128
GWAS1002739_H GCST90019510 High density lipoprotein cholesterol levels 313,372 European ancestry individuals, 5,573 African ancestry individuals, 6,689 South Asian ancestry individuals T NR 8E-21 20.097 rs483082 0.029 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:33462484
GWAS1002750_H GCST90019523 Triglyceride levels 342,233 European ancestry individuals, 6,014 African ancestry individuals, 7,330 South Asian ancestry individuals T NR 2E-219 218.699 rs483082 0.0934 triglyceride measurement (EFO:0004530)
 PMID:33462484
GWAS1003031_H GCST90241285 Glutathione S-transferase Mu 1 levels (GSTM1.7239.9.3) 3,301 European ancestry individuals T 0.231 4E-21 20.398 rs483082 0.27 glutathione S-transferase Mu 1 measurement (EFO:0801638)
 PMID:29875488
GWAS1003134_H GCST90295950 Triglyceride to HDL cholesterol ratio 185,749 European ancestry individuals T 0.2364 9E-168 167.046 rs483082 0.1232 triglyceride:HDL cholesterol ratio (EFO:0007929)
 PMID:38200128
GWAS1003148_H GCST90092966 Triglyceride levels in small LDL 115,082 European ancestry individuals G 0.763461 1E-52 52 rs483082 0.0720203 triglyceride measurement (EFO:0004530)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
GWAS1003289_H GCST90019518 Sex hormone-binding globulin levels 310,323 European ancestry individuals, 5,523 African ancestry individuals, 6,638 South Asian ancestry individuals T NR 7E-15 14.155 rs483082 0.0242 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:33462484
GWAS1003544_H GCST90019513 Lipoprotein (a) levels 272,573 European ancestry individuals, 5,018 African ancestry individuals, 6,453 South Asian ancestry individuals T NR 6E-46 45.222 rs483082 0.0473 lipoprotein A measurement (EFO:0006925)
 PMID:33462484
GWAS1003705_H GCST90295951 Triglyceride to HDL cholesterol ratio 216,649 European ancestry individuals T 0.2355 3E-57 56.523 rs483082 0.0683 triglyceride:HDL cholesterol ratio (EFO:0007929)
 PMID:38200128
None Available GCST90019501 Total cholesterol levels 342,508 European ancestry individuals, 6,014 African ancestry individuals, 7,336 South Asian ancestry individuals T NR 2E-21 20.699 rs483082 0.0282 total cholesterol measurement (EFO:0004574)
 PMID:33462484
GWAS1004478_H GCST90270118 Multi-trait sex score 141,980 European ancestry males ? NR 9E-39 38.046 rs483082 N/A sexual dimorphism measurement (EFO:0021796)
 PMID:37277458
GWAS1006776_H GCST90270117 Multi-trait sum score 161,906 European ancestry females ? NR 2E-19 18.699 rs483082 N/A complex trait (EFO:0010578)
 PMID:37277458
GWAS1006962_H GCST90302116 Ratio of triglycerides to phosphoglycerides 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.2279 2E-104 103.699 rs483082 0.1036 triglyceride measurement (EFO:0004530)
phospholipid measurement (EFO:0004639)
 PMID:38448586
GWAS1013615_H GCST90060306 Sphingomyelin_38:1_[M+H]1+ levels 13,814 British ancestry individuals T NR 3E-11 10.523 rs483082 0.0915741 sphingomyelin measurement (EFO:0010118)
 PMID:34503513
GWAS1014467_H GCST90019498 Aspartate aminotransferase to alanine aminotransferase ratio 341,165 European ancestry individuals, 5,981 African ancestry individuals, 7,309 South Asian ancestry individuals T NR 1E-47 47 rs483082 0.043 aspartate aminotransferase to alanine aminotransferase ratio (EFO:0010934)
 PMID:33462484
GWAS1016184_H GCST90019499 C-reactive protein levels 341,805 European ancestry individuals, 6,006 African ancestry individuals, 7,316 South Asian ancestry individuals T NR 3E-579 578.523 rs483082 0.152 C-reactive protein measurement (EFO:0004458)
 PMID:33462484
GWAS1017104_H GCST90060657 Sphingomyelin(34:0)_[M+H]1+ levels 5,662 Pakistani ancestry individuals A NR 2E-11 10.699 rs483082 0.086 sphingomyelin measurement (EFO:0010118)
 PMID:34503513
GWAS1017425_H GCST90060553 Triacylglycerol_56:6_[M+NH4]1+ levels 13,814 British ancestry individuals T NR 1E-11 11 rs483082 0.113594 triglyceride measurement (EFO:0004530)
 PMID:34503513
None Available GCST90060554 Triacylglycerol_56:5_[M+NH4]1+ levels 13,814 British ancestry individuals T NR 3E-10 9.523 rs483082 0.109132 triglyceride measurement (EFO:0004530)
 PMID:34503513
GWAS1017845_H GCST90086794 Serum levels of protein ARFGAP1 5,356 Icelandic ancestry individuals T 0.2146 2E-25 24.699 rs483082 0.22885 blood protein measurement (EFO:0007937)
 PMID:35078996
GWAS1018150_H GCST90087339 Serum levels of protein TP53I11 5,363 Icelandic ancestry individuals T 0.2146 2E-91 90.699 rs483082 0.450879 blood protein measurement (EFO:0007937)
 PMID:35078996
GWAS1018216_H GCST90087905 Serum levels of protein AKT2 5,356 Icelandic ancestry individuals T 0.2146 1E-100 100 rs483082 0.456005 blood protein measurement (EFO:0007937)
 PMID:35078996
GWAS1018236_H GCST90089938 Serum levels of protein CUZD1 5,363 Icelandic ancestry individuals T 0.2146 6E-261 260.222 rs483082 0.721395 blood protein measurement (EFO:0007937)
 PMID:35078996
GWAS1018318_H GCST90089955 Serum levels of protein HBQ1 5,361 Icelandic ancestry individuals T 0.2146 8E-162 161.097 rs483082 0.576882 blood protein measurement (EFO:0007937)
 PMID:35078996
GWAS1018321_H GCST90088110 Serum levels of protein HDAC8 5,352 Icelandic ancestry individuals T 0.2146 3E-26 25.523 rs483082 0.221313 blood protein measurement (EFO:0007937)
 PMID:35078996
GWAS1018351_H GCST90090624 Serum levels of protein PSG5 5,361 Icelandic ancestry individuals T 0.2146 5E-43 42.302 rs483082 0.307765 blood protein measurement (EFO:0007937)
 PMID:35078996
None Available GCST90086380 Serum levels of protein FAM159B 5,365 Icelandic ancestry individuals T 0.2146 7E-129 128.155 rs483082 0.531785 blood protein measurement (EFO:0007937)
 PMID:35078996
GWAS1018393_H GCST90089474 Serum levels of protein NPTX2 5,366 Icelandic ancestry individuals T 0.2146 6E-38 37.222 rs483082 0.29249 blood protein measurement (EFO:0007937)
 PMID:35078996
GWAS1018888_H GCST90090383 Serum levels of protein TMCC3 5,366 Icelandic ancestry individuals T 0.2146 2E-156 155.699 rs483082 0.580987 blood protein measurement (EFO:0007937)
 PMID:35078996
GWAS1018896_H GCST90090553 Serum levels of protein CRYZL1 5,363 Icelandic ancestry individuals T 0.2146 4E-89 88.398 rs483082 0.4428 blood protein measurement (EFO:0007937)
 PMID:35078996
GWAS1018999_H GCST90089353 Serum levels of protein GGT2 5,366 Icelandic ancestry individuals T 0.2146 2E-113 112.699 rs483082 0.500208 blood protein measurement (EFO:0007937)
 PMID:35078996
GWAS1019106_H GCST90089593 Serum levels of protein HLA-DRB3 5,351 Icelandic ancestry individuals T 0.2146 5E-34 33.302 rs483082 0.260342 blood protein measurement (EFO:0007937)
 PMID:35078996
GWAS1021914_H GCST90019492 Alanine aminotransferase levels 342,387 European ancestry individuals, 6,017 African ancestry individuals, 7,325 South Asian ancestry individuals T NR 1E-19 19 rs483082 0.0269 serum alanine aminotransferase measurement (EFO:0004735)
 PMID:33462484
None Available GCST90060842 Phosphatidylcholine-O(39:1)_[M+H]1+/Phosphatidylethanolamine-P(39:0)_[M+H]1+ levels 5,662 Pakistani ancestry individuals G NR 2E-11 10.699 rs483082 0.0477 phosphatidylcholine measurement (EFO:0010226)
 PMID:34503513
GWAS1024694_H GCST90060189 Diacylglycerol_36:3_[M+H-H2O]1+ levels 13,814 British ancestry individuals T NR 4E-10 9.398 rs483082 0.0784156 diacylglycerol 36:3 measurement (EFO:0020062)
 PMID:34503513
GWAS1025863_H GCST90060199 Diacylglycerol_38:6_[M+H-H2O]1+ levels 13,814 British ancestry individuals T NR 6E-12 11.222 rs483082 0.0807634 diglyceride measurement (EFO:0010223)
 PMID:34503513
GWAS1026140_H GCST90060200 Diacylglycerol_38:5_[M+H-H2O]1+ levels 13,814 British ancestry individuals T NR 6E-16 15.222 rs483082 0.0786293 diacylglycerol 38:5 measurement (EFO:0020067)
 PMID:34503513
GWAS1027233_H GCST90019496 Apolipoprotein B levels 340,860 European ancestry individuals, 5,962 African ancestry individuals, 7,275 South Asian ancestry individuals T NR 6E-125 124.222 rs483082 0.0706 apolipoprotein B measurement (EFO:0004615)
 PMID:33462484
GWAS1028098_H GCST90019495 Apolipoprotein A1 levels 311,601 European ancestry individuals, 5,550 African ancestry individuals, 6,682 South Asian ancestry individuals T NR 5E-19 18.302 rs483082 0.0277 apolipoprotein A 1 measurement (EFO:0004614)
 PMID:33462484
GWAS1028480_H GCST90239610 Triglyceride levels 76,053 Taiwanese ancestry individuals ? NR 9E-73 72.046 rs483082 7.4509 triglyceride measurement (EFO:0004530)
 PMID:36329257
None Available GCST90060188 Diacylglycerol_36:4_[M+H-H2O]1+ levels 13,814 British ancestry individuals T NR 4E-10 9.398 rs483082 0.0791701 diacylglycerol 36:4 measurement (EFO:0020063)
 PMID:34503513
None Available GCST90245008 2-palmitoyl-GPE (16:0) levels 14,296 European ancestry individuals T 0.2365 2E-11 10.699 rs483082 0.07917878 2-palmitoyl-GPE (16:0) measurement (EFO:0800255)
 PMID:36357675
GWAS1030414_H GCST90244955 1-palmitoyl-GPE (16:0) levels 14,296 European ancestry individuals T 0.2361 2E-15 14.699 rs483082 0.093675815 1-palmitoyl-GPE (16:0) measurement (EFO:0800245)
 PMID:36357675
GWAS1032084_H GCST90239661 Triglyceride levels 40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals ? NR 6E-787 786.222 rs483082 N/A triglyceride measurement (EFO:0004530)
 PMID:34887591
GWAS1041151_H GCST90319877 Cirrhosis 15,225 European ancestry cases, 1,564,786 European ancestry controls T NR 9E-14 13.046 rs483082 0.1062 cirrhosis of liver (EFO:0001422)
 PMID:38632349
GWAS1043930_H GCST90319878 Cirrhosis 15,225 European ancestry cases, 1,564,786 European ancestry controls, 2,551 East Asian ancestry cases, 176,175 East Asian ancestry controls, 224 African American cases, 21,969 African American controls, 265 Hispanic cases, 19,117 Hispanic controls T NR 3E-14 13.523 rs483082 0.1008 cirrhosis of liver (EFO:0001422)
 PMID:38632349
GWAS1044214_H GCST90265748 Plasma oleoyl-arachidonoyl-glycerol (18:1/20:4) [2]* levels in chronic kidney disease 4,585 European ancestry individuals T 0.21 4E-14 13.398 rs483082 0.181 oleoyl-arachidonoyl-glycerol (18:1/20:4) [2] measurement (EFO:0800508)
 PMID:37277652
None Available GCST90265747 Plasma oleoyl-arachidonoyl-glycerol (18:1/20:4) [1]* levels in chronic kidney disease 4,682 European ancestry individuals T 0.21 3E-14 13.523 rs483082 0.174 oleoyl-arachidonoyl-glycerol (18:1/20:4) [1] measurement (EFO:0800507)
 PMID:37277652
None Available GCST90265453 Plasma linoleoyl-arachidonoyl-glycerol (18:2/20:4) [1]* levels in chronic kidney disease 4,526 European ancestry individuals T 0.21 1E-13 13 rs483082 0.184 linoleoyl-arachidonoyl-glycerol (18:2/20:4) [1] measurement (EFO:0800499)
 PMID:37277652
GWAS1046107_H GCST90265454 Plasma linoleoyl-arachidonoyl-glycerol (18:2/20:4) [2]* levels in chronic kidney disease 4,527 European ancestry individuals T 0.21 3E-12 11.523 rs483082 0.184 linoleoyl-arachidonoyl-glycerol (18:2/20:4) [2] measurement (EFO:0800500)
 PMID:37277652
None Available GCST90134626 Cerebrospinal fluid amyloid beta 42 levels in abnormal amyloid levels 3,775 European ancestry individuals T 0.4448 1E-23 23 rs483082 10.029 amyloid-beta measurement (EFO:0005194)
 PMID:36066633
None Available GCST90091629 Fasting cholesterol esters in very large VLDL null T 0.248956987 3E-8 7.523 rs483082 0.142256 very low density lipoprotein cholesterol measurement (EFO:0008317)
esterified cholesterol measurement (EFO:0008589)
 PMID:34610981
None Available GCST90091631 Fasting total lipids in very large VLDL null T 0.248956987 3E-8 7.523 rs483082 0.141365 very low density lipoprotein cholesterol measurement (EFO:0008317)
lipid measurement (EFO:0004529)
 PMID:34610981
None Available GCST90091725 Postprandial polyunsaturated fatty acids null T 0.243949 3E-9 8.523 rs483082 0.237711 polyunsaturated fatty acid measurement (EFO:0010733)
 PMID:34610981
None Available GCST90091726 Postprandial remnant cholesterol null T 0.244495 7E-9 8.155 rs483082 0.230277 remnant cholesterol measurement (EFO:0010815)
 PMID:34610981
None Available GCST90091585 Fasting polyunsaturated fatty acids null T 0.244384 5E-14 13.302 rs483082 0.287426 polyunsaturated fatty acid measurement (EFO:0010733)
 PMID:34610981
None Available GCST90091586 Fasting remnant cholesterol null T 0.244662 6E-11 10.222 rs483082 0.24863 remnant cholesterol measurement (EFO:0010815)
 PMID:34610981
None Available GCST90091636 Fasting cholesterol esters in very small VLDL null T 0.244656 3E-13 12.523 rs483082 0.277668 very low density lipoprotein cholesterol measurement (EFO:0008317)
esterified cholesterol measurement (EFO:0008589)
 PMID:34610981
None Available GCST90091638 Fasting total lipids in very small VLDL null T 0.244656 1E-8 8 rs483082 0.217714 very low density lipoprotein cholesterol measurement (EFO:0008317)
lipid measurement (EFO:0004529)
 PMID:34610981
None Available GCST90091769 Postprandial cholesterol esters in very large VLDL null T 0.246200619 1E-8 8 rs483082 0.144146 very low density lipoprotein cholesterol measurement (EFO:0008317)
esterified cholesterol measurement (EFO:0008589)
 PMID:34610981
None Available GCST90091508 Fasting apolipoprotein B null T 0.244662 2E-12 11.699 rs483082 0.26797 apolipoprotein B measurement (EFO:0004615)
 PMID:34610981
None Available GCST90091675 Postprandial linoleic acid (18:2) null T 0.243949 2E-9 8.699 rs483082 0.241584 linoleic acid measurement (EFO:0006807)
 PMID:34610981
None Available GCST90091778 Postprandial total lipids in very small VLDL null T 0.244437 3E-10 9.523 rs483082 0.251112 very low density lipoprotein cholesterol measurement (EFO:0008317)
lipid measurement (EFO:0004529)
 PMID:34610981
None Available GCST90091650 Postprandial apolipoprotein B null T 0.244495 7E-9 8.155 rs483082 0.230723 apolipoprotein B measurement (EFO:0004615)
 PMID:34610981
None Available GCST90091658 Postprandial omega-6 fatty acids null T 0.243949 1E-10 10 rs483082 0.257838 omega-6 polyunsaturated fatty acid measurement (EFO:0005680)
 PMID:34610981
None Available GCST90091534 Fasting linoleic acid (18:2) null T 0.244384 5E-16 15.302 rs483082 0.309285 linoleic acid measurement (EFO:0006807)
 PMID:34610981
None Available GCST90448452 Memory decline in impaired cognition 4,478 European ancestry males ? NR 2E-12 11.699 rs483082 0.039025 memory performance (EFO:0004874)
 PMID:37984853
None Available GCST90448433 Baseline memory 13,154 European ancestry females ? NR 1E-10 10 rs483082 0.081685 memory performance (EFO:0004874)
 PMID:37984853
None Available GCST90448451 Memory decline 11,062 European ancestry males ? NR 9E-14 13.046 rs483082 0.0118 memory performance (EFO:0004874)
 PMID:37984853
None Available GCST90448425 Baseline memory in impaired cognition 4,478 European ancestry males ? NR 2E-7 6.699 rs483082 0.162344 memory performance (EFO:0004874)
 PMID:37984853
None Available GCST90448462 Memory decline in normal cognition 7,839 European ancestry females ? NR 5E-10 9.302 rs483082 0.00911 memory performance (EFO:0004874)
 PMID:37984853
None Available GCST90448424 Baseline memory 11,062 European ancestry males ? NR 1E-10 10 rs483082 0.097767 memory performance (EFO:0004874)
 PMID:37984853
None Available GCST90448434 Baseline memory in impaired cognition 3,987 European ancestry females ? NR 8E-9 8.097 rs483082 0.195225 memory performance (EFO:0004874)
 PMID:37984853
None Available GCST90448453 Memory decline in normal cognition 4,950 European ancestry males ? NR 0.000001 6 rs483082 0.007859 memory performance (EFO:0004874)
 PMID:37984853
None Available GCST90454454 Metabolic syndrome 24,171 Taiwanese ancestry cases, 83,059 Taiwanese ancestry controls G 0.1848 2E-11 10.699 rs483082 0.091667 metabolic syndrome (EFO:0000195)
 PMID:38201907
None Available GCST90448460 Memory decline 13,154 European ancestry females ? NR 9E-15 14.046 rs483082 0.011122 memory performance (EFO:0004874)
 PMID:37984853
Database Acc Id Source(s)
GWAS Catalog GCST007437 GWAS Catalog
  GCST90060554 GWAS Catalog
  GCST90091778 GWAS Catalog

RGD Curation Notes
Note Type Note Reference