GWAS750018_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS750018_H (vital capacity QTL GWAS750018 (human)) Homo sapiens

Symbol: GWAS750018_H
Name: vital capacity QTL GWAS750018 (human)
RGD ID: 407101042
Trait: vital capacity
LOD Score: Not Available
P Value: 2.0E-10
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh382237,369,499 - 237,369,500RGD_MAPPER_PIPELINEGRCh38
GRCh372238,278,142 - 238,278,143RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS750018_HHumanvital capacity  IAGPrs2645775405850206 GWAS_CATALOGPMID:30595370
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1318630COL6A3collagen type VI alpha 3 chain2237324018237414164Human

Position Markers

Peak: (rs2645775)
Human AssemblyChrPosition (strand)Source
GRCh382237,369,499 - 237,369,500RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407101042GWAS750018_Hvital capacity QTL GWAS750018 (human)2e-10vital capacity2237369499237369500Human
2289332BW376_HBody weight QTL 376 (human)1.870.00168Body fat amountabdominal2213765566239765566Human
407201116GWAS850092_Hcentral corneal thickness QTL GWAS850092 (human)9e-22central corneal thickness2237369499237369500Human
407204152GWAS853128_Hcorneal resistance factor QTL GWAS853128 (human)1e-32corneal resistance factor2237369499237369500Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS750018_H GCST007081 Lung function (FVC) approximately 372,000 European ancestry individuals ? NR 2E-10 9.699 rs2645775 N/A vital capacity (EFO:0004312)
 PMID:30595370
GWAS850092_H GCST90102518 Central corneal thickness (MTAG) 17,803 European ancestry individuals A 0.2172 9E-22 21.046 rs2645775 2.673186 central corneal thickness (EFO:0005213)
 PMID:35446358
GWAS853128_H GCST90102517 Corneal resistance factor (MTAG) 123,734 European ancestry individuals A 0.2214 1E-32 32 rs2645775 0.055535 corneal resistance factor (EFO:0010067)
 PMID:35446358
Database Acc Id Source(s)
GWAS Catalog GCST007081 GWAS Catalog

RGD Curation Notes
Note Type Note Reference