GWAS745768_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS745768_H (eye color QTL GWAS745768 (human)) Homo sapiens

Symbol: GWAS745768_H
Name: eye color QTL GWAS745768 (human)
RGD ID: 407096792
Trait: eye color
LOD Score: Not Available
P Value: 5E-163
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381528,285,036 - 28,285,037RGD_MAPPER_PIPELINEGRCh38
GRCh371528,530,182 - 28,530,183RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS745768_HHumaneye color  IAGPrs1667394405850206 GWAS_CATALOGPMID:30166351
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1317498HERC2HECT and RLD domain containing E3 ubiquitin protein ligase 2152811104028322179Human

Position Markers

Peak: (rs1667394)
Human AssemblyChrPosition (strand)Source
GRCh381528,285,036 - 28,285,037RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2289410BW327_HBody weight QTL 327 (human)3.320.0001Body fat amount151998012945980129Human
407096801GWAS745777_Heye color QTL GWAS745777 (human)1e-145eye color152828503628285037Human
407127431GWAS776407_Hhair color QTL GWAS776407 (human)3e-77hair color152828503628285037Human
1559411SCL107_HSerum cholesterol level QTL 107 (human)3.88Lipid leveltriglyceride152654355252543552Human
406964676GWAS613652_Hsuntan QTL GWAS613652 (human)4e-78suntan152828503628285037Human
407009925GWAS658901_Hhair color QTL GWAS658901 (human)6e-35hair color152828503628285037Human
407096804GWAS745780_Heye color QTL GWAS745780 (human)3e-176eye color152828503628285037Human
2289420BW314_HBody weight QTL 314 (human)2.720.0003Body weightlean mass151998012945980129Human
407127434GWAS776410_Hhair color QTL GWAS776410 (human)4e-22hair color152828503628285037Human
1643273BW330_HBody Weight QTL 330 (human)1.050.014Body weightbody mass index152686671952866719Human
2289430BMD7_HBone mineral density QTL 7 (human)3.320.0001Bone mineral density151998012945980129Human
407009911GWAS658887_Heye color QTL GWAS658887 (human)2e-53eye color152828503628285037Human
407006069GWAS655045_Heye color QTL GWAS655045 (human)2e-20eye color152828503628285037Human
407066100GWAS715076_Hadiponectin measurement QTL GWAS715076 (human)0.000002adiponectin measurementblood adiponectin level (CMO:0000485)152828503628285037Human
1643523BW284_HBody Weight QTL 284 (human)1.950.0013Body weight152179288947792889Human
407096792GWAS745768_Heye color QTL GWAS745768 (human)5e-163eye color152828503628285037Human
407009917GWAS658893_Heye color QTL GWAS658893 (human)1e-241eye color152828503628285037Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS613652_H GCST005897 Low tan response 46,768 European ancestry low tanning cases, 74,528 European ancestry moderate and high tanning controls C NR 4E-78 77.398 rs1667394 0.226 suntan (EFO:0004279)
 PMID:29739929
GWAS655045_H GCST001723 Eye color 175 European ancestry individuals C 0.28 2E-20 19.699 rs1667394 0.353 eye color (EFO:0003949)
 PMID:23118974
GWAS658887_H GCST000117 Blue vs. green eyes 2,986 Icelandic ancestry individuals A 0.98 2E-53 52.699 rs1667394 6.74 eye color (EFO:0003949)
 PMID:17952075
GWAS658893_H GCST000120 Blue vs. brown eyes 2,986 Icelandic ancestry individuals A 0.88 1E-241 241 rs1667394 29.43 eye color (EFO:0003949)
 PMID:17952075
GWAS658901_H GCST000118 Blond vs. brown hair color 2,986 Icelandic ancestry individuals A 0.88 6E-35 34.222 rs1667394 4.94 hair color (EFO:0003924)
 PMID:17952075
GWAS715076_H GCST012166 Adiponectin levels 606 European ancestry high cardiovascular risk elderly women T 0.38 0.000002 5.699 rs1667394 0.134 adiponectin measurement (EFO:0004502)
 PMID:33562295
GWAS745768_H GCST007489 Eye color traits 4,988 Spanish ancestry individuals ? NR 5E-163 162.302 rs1667394 1.843 eye color (EFO:0003949)
 PMID:30166351
GWAS745777_H GCST007489 Eye color traits 4,988 Spanish ancestry individuals ? NR 1E-145 145 rs1667394 1.5500612 eye color (EFO:0003949)
 PMID:30166351
GWAS745780_H GCST007489 Eye color traits 4,988 Spanish ancestry individuals ? NR 3E-176 175.523 rs1667394 0.6088 eye color (EFO:0003949)
 PMID:30166351
GWAS776407_H GCST90095476 Blond vs. brown/black hair color 12,398 European ancestry individuals C NR 3E-77 76.523 rs1667394 1.01451 hair color (EFO:0003924)
 PMID:34737440
GWAS776410_H GCST90095477 Brown vs. black hair color 10,990 European ancestry individuals C NR 4E-22 21.398 rs1667394 0.634748 hair color (EFO:0003924)
 PMID:34737440
Database Acc Id Source(s)
GWAS Catalog GCST007489 GWAS Catalog

RGD Curation Notes
Note Type Note Reference