GWAS731143_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS731143_H (free cholesterol:total lipids ratio, intermediate density lipoprotein measurement QTL GWAS731143 (human)) Homo sapiens

Symbol: GWAS731143_H
Name: free cholesterol:total lipids ratio, intermediate density lipoprotein measurement QTL GWAS731143 (human)
RGD ID: 407082167
Trait: free cholesterol:total lipids ratio, intermediate density lipoprotein measurement
Measurement Type: blood intermediate density lipoprotein cholesterol level   (CMO:0001562)    
LOD Score: Not Available
P Value: 4.0E-11
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38193,270,998 - 93,270,999RGD_MAPPER_PIPELINEGRCh38
GRCh37193,736,555 - 93,736,556RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS731143_HHumanblood intermediate density lipoprotein cholesterol level  IAGPrs2296558405850206Based on the EFO term IDGWAS_CATALOGPMID:38448586

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS731143_HHumanfree cholesterol:total lipids ratio  IAGPrs2296558405850206 GWAS_CATALOGPMID:38448586
GWAS731143_HHumanintermediate density lipoprotein measurement  IAGPrs2296558405850206 GWAS_CATALOGPMID:38448586
Experimental Data Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1601798CCDC18coiled-coil domain containing 1819317991393278730Human

Position Markers

Peak: (rs2296558)
Human AssemblyChrPosition (strand)Source
GRCh38193,270,998 - 93,270,999RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407082167GWAS731143_Hfree cholesterol:total lipids ratio, intermediate density lipoprotein measurement QTL GWAS731143 (human)4e-11free cholesterol:total lipids ratio, intermediate density lipoprotein measurementblood intermediate density lipoprotein cholesterol level (CMO:0001562)19327099893270999Human
2316890GLUCO302_HGlucose level QTL 302 (human)0.005Glucose level16853299294532992Human
2289499BW445_HBody weight QTL 445 (human)2.26Body morphometrywaist to hip ratio16853299294532992Human
1581539BP75_HBlood pressure QTL 75 (human)2.40.001Blood pressurepulse pressure16853299294532992Human
2292793PRSTS24_HProstate tumor susceptibility QTL 24 (human)Prostate tumor susceptibilitylate onset16853299294532992Human
1559226SLEP4_HSerum leptin concentration QTL 4 (human)3.4Hormone levelleptin181532913107532913Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS731143_H GCST90301980 Free cholesterol to total lipids ratio in IDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.3669 4E-11 10.398 rs2296558 0.0266 free cholesterol:total lipids ratio (EFO:0020945)
intermediate density lipoprotein measurement (EFO:0008595)
 PMID:38448586
Database Acc Id Source(s)
GWAS Catalog GCST90301980 GWAS Catalog

RGD Curation Notes
Note Type Note Reference