GWAS726547_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS726547_H (eosinophil count QTL GWAS726547 (human)) Homo sapiens

Symbol: GWAS726547_H
Name: eosinophil count QTL GWAS726547 (human)
RGD ID: 407077571
Trait: eosinophil quantity   (VT:0002602)    
Measurement Type: blood eosinophil count   (CMO:0000033)    
LOD Score: Not Available
P Value: 3.0E-18
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38316,866,675 - 16,866,676RGD_MAPPER_PIPELINEGRCh38
GRCh37316,908,186 - 16,908,187RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS726547_HHumanblood eosinophil count  IAGPrs6766037405850206Based on the EFO term IDGWAS_CATALOGPMID:34594039

Vertebrate Trait
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS726547_HHumaneosinophil quantity  IAGPrs6766037405850206Based on the EFO term IDGWAS_CATALOGPMID:34594039

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS726547_HHumaneosinophil count  IAGPrs6766037405850206 GWAS_CATALOGPMID:34594039
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Vertebrate Trait

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Position Markers

Peak: (rs6766037)
Human AssemblyChrPosition (strand)Source
GRCh38316,866,675 - 16,866,676RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407077571GWAS726547_Heosinophil count QTL GWAS726547 (human)3e-18eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)31686667516866676Human
407079307GWAS728283_Hmonocyte count QTL GWAS728283 (human)1e-08monocyte quantity (VT:0000223)blood monocyte count (CMO:0000032)31686667516866676Human
2316345GLUCO224_HGlucose level QTL 224 (human)1.270.008Glucose level3121543441Human
406963690GWAS612666_Hbasophil percentage of leukocytes QTL GWAS612666 (human)7e-49basophil percentage of leukocytesblood basophil count to total leukocyte count ratio (CMO:0000368)31686667516866676Human
406963629GWAS612605_Hbasophil count QTL GWAS612605 (human)2e-50basophil quantity (VT:0002607)blood basophil count (CMO:0000034)31686667516866676Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS612605_H GCST90002379 Basophil count 408,112 British individuals G 0.2181 2E-50 49.699 rs6766037 0.04020344 basophil count (EFO:0005090)
 PMID:32888494
GWAS612666_H GCST90002380 Basophil percentage of white cells 408,112 British individuals G 0.218113 7E-49 48.155 rs6766037 0.039579988 basophil percentage of leukocytes (EFO:0007992)
 PMID:32888494
GWAS726547_H GCST90018953 Eosinophil counts 349,856 European ancestry individuals, 93,063 East Asian ancestry individuals G NR 3E-18 17.523 rs6766037 0.0182 eosinophil count (EFO:0004842)
 PMID:34594039
GWAS728283_H GCST90018967 Monocyte count 349,856 European ancestry individuals, 95,119 East Asian ancestry individuals G NR 1E-8 8 rs6766037 0.0154 monocyte count (EFO:0005091)
 PMID:34594039
Database Acc Id Source(s)
GWAS Catalog GCST90018953 GWAS Catalog

RGD Curation Notes
Note Type Note Reference