GWAS712326_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS712326_H (small vessel stroke QTL GWAS712326 (human)) Homo sapiens

Symbol: GWAS712326_H
Name: small vessel stroke QTL GWAS712326 (human)
RGD ID: 407063350
Trait: small vessel stroke
LOD Score: Not Available
P Value: 1.0E-6
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381156,232,382 - 156,232,383RGD_MAPPER_PIPELINEGRCh38
GRCh371156,202,173 - 156,202,174RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
5507928PMF1-BGLAPPMF1-BGLAP readthrough1156212988156243332Human
1317520PMF1polyamine modulated factor 11156213007156240042Human


Peak: (rs1052053)
Human AssemblyChrPosition (strand)Source
GRCh381156,232,382 - 156,232,383RGD_MAPPER_PIPELINE


1 to 10 of 38 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597164826GWAS1260900_Hfactor VIII measurement, Ischemic stroke QTL GWAS1260900 (human)3e-12factor VIII measurement, Ischemic stroke1156232382156232383Human
596979606GWAS1099125_Hsmall vessel stroke QTL GWAS1099125 (human)0.000001small vessel stroke1156232382156232383Human
596979921GWAS1099440_HIschemic stroke, factor VII measurement QTL GWAS1099440 (human)8e-11Ischemic stroke, factor VII measurement1156232382156232383Human
596978768GWAS1098287_Hstroke QTL GWAS1098287 (human)3e-14stroke1156232382156232383Human
596959825GWAS1079344_Hglomerular filtration rate QTL GWAS1079344 (human)9e-24glomerular filtration rate1156232382156232383Human
407393870GWAS1042846_HIschemic stroke, plasminogen activator inhibitor 1 measurement QTL GWAS1042846 (human)6e-11Ischemic stroke, plasminogen activator inhibitor 1 measurement1156232382156232383Human
597289055GWAS1385129_Hstroke QTL GWAS1385129 (human)2e-12stroke1156232382156232383Human
596975901GWAS1095420_HIschemic stroke QTL GWAS1095420 (human)4e-11Ischemic stroke1156232382156232383Human
596960282GWAS1079801_Hglomerular filtration rate QTL GWAS1079801 (human)1e-23glomerular filtration rate1156232382156232383Human
596975578GWAS1095097_Hstroke QTL GWAS1095097 (human)2e-12stroke1156232382156232383Human

1 to 10 of 38 rows


1 to 17 of 17 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1258812_H GCST90129552 Ischemic stroke or factor XI levels (pleiotropy) 16,169 European ancestry individuals with measurements, 60,341 European, African American, East Asian, South Asian, mixed Asian or Latin American ischemic stroke cases, 454,450 European, African American, East Asian, South Asian, mixed Asian or Latin American ischemic stroke controls ? NR 7E-11 10.155 rs1052053 N/A factor XI measurement (EFO:0004694)
Ischemic stroke (HP:0002140)
 PMID:35285134
GWAS1259691_H GCST90129549 Ischemic stroke or factor VII levels (pleiotropy) 27,495 European or African American individuals with measurements, 60,341 European, African American, East Asian, South Asian, mixed Asian or Latin American ischemic stroke cases, 454,450 European, African American, East Asian, South Asian, mixed Asian or Latin American ischemic stroke controls ? NR 8E-11 10.097 rs1052053 N/A Ischemic stroke (HP:0002140)
factor VII measurement (EFO:0004619)
 PMID:35285134
GWAS1260733_H GCST90129555 Ischemic stroke or plasminogen activator inhibitor 1 levels (pleiotropy) 60,341 European, African American, East Asian, South Asian, mixed Asian or Latin American ischemic stroke cases, 454,450 European, African American, East Asian, South Asian, mixed Asian or Latin American ischemic stroke controls, 19,599 European ancestry individuals with measurements ? NR 6E-11 10.222 rs1052053 N/A Ischemic stroke (HP:0002140)
plasminogen activator inhibitor 1 measurement (EFO:0004792)
 PMID:35285134
GWAS1260900_H GCST90129550 Ischemic stroke or factor VIII levels (pleiotropy) 32,610 European, African American, East Asian, South Asian or Hispanic individuals with measurements, 60,341 European, African American, East Asian, South Asian, mixed Asian or Latin American ischemic stroke cases, 454,450 European, African American, East Asian, South Asian, mixed Asian or Latin American ischemic stroke controls ? NR 3E-12 11.523 rs1052053 N/A factor VIII measurement (EFO:0004630)
Ischemic stroke (HP:0002140)
 PMID:35285134
GWAS1756573_H GCST90129551 Ischemic stroke or von Willebrand factor levels (pleiotropy) 60,341 European, African American, East Asian, South Asian, mixed Asian or Latin American ischemic stroke cases, 454,450 European, African American, East Asian, South Asian, mixed Asian or Latin American ischemic stroke controls, 46,354 European, African American or Hispanic individuals with measurements ? NR 1E-10 10 rs1052053 N/A Ischemic stroke (HP:0002140)
von Willebrand factor quality (OBA:1000199)
 PMID:35285134
None Available GCST90129554 Ischemic stroke or tissue plasminogen activator levels (pleiotropy) 60,341 European, African American, East Asian, South Asian, mixed Asian or Latin American ischemic stroke cases, 454,450 European, African American, East Asian, South Asian, mixed Asian or Latin American ischemic stroke controls, 26,929 European ancestry individuals with measurements ? NR 7E-11 10.155 rs1052053 N/A Ischemic stroke (HP:0002140)
tissue plasminogen activator amount (OBA:2050207)
 PMID:35285134
GWAS1756662_H GCST90129553 Ischemic stroke or fibrinogen levels (pleiotropy) 120,246 European ancestry individuals with measurements, 60,341 European, African American, East Asian, South Asian, mixed Asian or Latin American ischemic stroke cases, 454,450 European, African American, East Asian, South Asian, mixed Asian or Latin American ischemic stroke controls ? NR 5E-10 9.302 rs1052053 N/A Ischemic stroke (HP:0002140)
circulating fibrinogen levels (OBA:0000061)
 PMID:35285134
GWAS1381681_H GCST005841 Ischemic stroke (small-vessel) 5,386 European ancestry cases, 343,560 European ancestry controls, 5,096 East Asian ancestry cases, 28,195 East Asian ancestry controls, 314 South Asian ancestry cases, 6,707 South Asian ancestry controls, 694 African American cases, 15,146 African American controls, 134 Asian ancestry cases, 333 Asian ancestry controls, 86 Latin American cases, 692 Latin American controls ? NR 0.000001 6 rs1052053 N/A small vessel stroke (EFO:1001504)
 PMID:29531354
GWAS1382149_H GCST005838 Stroke 40,585 European ancestry cases, 406,111 European ancestry controls, 17,369 East Asian ancestry cases, 28,195 East Asian ancestry controls, 2,437 South Asian ancestry cases, 6,707 South Asian ancestry controls, 5,541 African American cases, 15,154 African American controls, 365 Asian ancestry cases, 333 Asian ancestry controls, 865 Latin American cases, 692 Latin American controls ? NR 3E-14 13.523 rs1052053 N/A stroke (EFO:0000712)
 PMID:29531354
GWAS1382486_H GCST006908 Ischemic stroke 34,217 European ancestry cases, 406,111 European ancestry controls ? NR 5E-9 8.302 rs1052053 N/A Ischemic stroke (HP:0002140)
 PMID:29531354
GWAS1384501_H GCST005843 Ischemic stroke 34,217 European ancestry cases, 406,111 European ancestry controls, 17,369 East Asian ancestry cases, 28,195 East Asian ancestry controls, 2,437 South Asian ancestry cases, 6,707 South Asian ancestry controls, 5,541 African American cases, 15,146 African American controls, 222 Asian ancestry cases, 333 Asian ancestry controls, 555 Latin American cases, 692 Latin American controls ? NR 4E-11 10.398 rs1052053 N/A Ischemic stroke (HP:0002140)
 PMID:29531354
GWAS1385129_H GCST006906 Stroke 40,585 European ancestry cases, 406,111 European ancestry controls ? NR 2E-12 11.699 rs1052053 N/A stroke (EFO:0000712)
 PMID:29531354
GWAS1443632_H GCST90428574 Myeloproliferative neoplasms (MTAG) at least 1,427 cases, at least 480,951 controls (MTAG boosted by telomere length and loss of chromosome Y samples) ? NR 3E-24 23.523 rs1052053 0.015 myeloproliferative disorder (EFO:0004251)
 PMID:37684235
GWAS1793404_H GCST90428448 Estimated glomerular filtration rate (cystatin c) 406,504 European ancestry individuals G NR 9E-24 23.046 rs1052053 0.021077 glomerular filtration rate (OBA:0003747)
 PMID:39256582
GWAS1802522_H GCST90479598 estimated glomerular filtration rate (eGFR, maximum, inv-norm transformed) 110,850 African American or Afro-Caribbean individuals, 55,242 Hispanic or Latin American individuals, 6,249 East Asian ancestry individuals, 398,886 European ancestry individuals A 0.5638 2E-11 10.699 rs1052053 0.01746 glomerular filtration rate (OBA:0003747)
 PMID:39024449
GWAS1802909_H GCST90428446 Estimated glomerular filtration rate (creatinine, cystatin c) 406,504 European ancestry individuals G NR 1E-23 23 rs1052053 0.021148 glomerular filtration rate (OBA:0003747)
 PMID:39256582
GWAS1807073_H GCST90428447 Estimated glomerular filtration rate (creatinine) 406,504 European ancestry individuals G NR 5E-11 10.302 rs1052053 0.0141049 glomerular filtration rate (OBA:0003747)
 PMID:39256582
1 to 17 of 17 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST005841 GWAS Catalog

Note Type Note Reference