GWAS703424_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS703424_H (eosinophil percentage of leukocytes QTL GWAS703424 (human)) Homo sapiens

Symbol: GWAS703424_H
Name: eosinophil percentage of leukocytes QTL GWAS703424 (human)
RGD ID: 407054448
Trait: eosinophil percentage of leukocytes
Measurement Type: blood eosinophil count to total leukocyte count ratio   (CMO:0000369)    
LOD Score: Not Available
P Value: 5.0E-20
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38124,209,557 - 4,209,558RGD_MAPPER_PIPELINEGRCh38
GRCh37124,318,723 - 4,318,724RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS703424_HHumanblood eosinophil count to total leukocyte count ratio  IAGPrs12820863405850206Based on the EFO term IDGWAS_CATALOGPMID:32888494

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS703424_HHumaneosinophil percentage of leukocytes  IAGPrs12820863405850206 GWAS_CATALOGPMID:32888494
Experimental Data Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Position Markers

Peak: (rs12820863)
Human AssemblyChrPosition (strand)Source
GRCh38124,209,557 - 4,209,558RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407369509GWAS1018485_Heosinophil count QTL GWAS1018485 (human)4e-09eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)1242095574209558Human
407054448GWAS703424_Heosinophil percentage of leukocytes QTL GWAS703424 (human)5e-20eosinophil percentage of leukocytesblood eosinophil count to total leukocyte count ratio (CMO:0000369)1242095574209558Human
407386731GWAS1035707_Heosinophil count QTL GWAS1035707 (human)5e-22eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)1242095574209558Human
407387373GWAS1036349_Hbasophil count, eosinophil count QTL GWAS1036349 (human)9e-11eosinophil quantity (VT:0002602)blood granulocyte count (CMO:0000111)1242095574209558Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS703424_H GCST90002382 Eosinophil percentage of white cells 408,112 British individuals T 0.35103 5E-20 19.302 rs12820863 0.021920718 eosinophil percentage of leukocytes (EFO:0007991)
 PMID:32888494
GWAS1018485_H GCST004606 Eosinophil counts 172,275 European ancestry individuals T 0.352 4E-9 8.398 rs12820863 0.02283322 eosinophil count (EFO:0004842)
 PMID:27863252
GWAS1035707_H GCST007065 Eosinophil counts approximately 440,000 European ancestry individuals ? NR 5E-22 21.302 rs12820863 N/A eosinophil count (EFO:0004842)
 PMID:30595370
GWAS1036349_H GCST004624 Sum eosinophil basophil counts 171,771 European ancestry individuals T 0.3521 9E-11 10.046 rs12820863 0.02513112 basophil count (EFO:0005090)
eosinophil count (EFO:0004842)
 PMID:27863252
Database Acc Id Source(s)
GWAS Catalog GCST90002382 GWAS Catalog

RGD Curation Notes
Note Type Note Reference