GWAS702092_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS702092_H (basal cell carcinoma QTL GWAS702092 (human)) Homo sapiens

Symbol: GWAS702092_H
Name: basal cell carcinoma QTL GWAS702092 (human)
RGD ID: 407053116
Trait: basal cell carcinoma
LOD Score: Not Available
P Value: 1.0E-8
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381241,860,596 - 241,860,597RGD_MAPPER_PIPELINEGRCh38
GRCh371242,023,898 - 242,023,899RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1319820EXO1exonuclease 11241847986241889939Human

Position Markers

Peak: (rs4149909)
Human AssemblyChrPosition (strand)Source
GRCh381241,860,596 - 241,860,597RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407002466GWAS651442_Heosinophil percentage of leukocytes QTL GWAS651442 (human)5e-12eosinophil percentage of leukocytesblood eosinophil count to total leukocyte count ratio (CMO:0000369)1241860596241860597Human
407054087GWAS703063_Hkeratinocyte carcinoma QTL GWAS703063 (human)2e-09keratinocyte carcinoma1241860596241860597Human
407356434GWAS1005410_Hsystolic blood pressure QTL GWAS1005410 (human)2e-08systolic blood pressuresystolic blood pressure (CMO:0000004)1241860596241860597Human
407362177GWAS1011153_Hbasal cell carcinoma QTL GWAS1011153 (human)4e-09basal cell carcinoma1241860596241860597Human
406994122GWAS643098_Heosinophil count QTL GWAS643098 (human)1e-10eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)1241860596241860597Human
407386465GWAS1035441_Hbasal cell carcinoma QTL GWAS1035441 (human)1e-26basal cell carcinoma1241860596241860597Human
407380243GWAS1029219_HUterine leiomyoma, breast carcinoma QTL GWAS1029219 (human)9e-15Uterine leiomyoma, breast carcinoma1241860596241860597Human
407363116GWAS1012092_Hbasal cell carcinoma QTL GWAS1012092 (human)7e-09basal cell carcinoma1241860596241860597Human
407355178GWAS1004154_Heosinophil count QTL GWAS1004154 (human)6e-09eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)1241860596241860597Human
407053116GWAS702092_Hbasal cell carcinoma QTL GWAS702092 (human)1e-08Uterine leiomyoma1241860596241860597Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS643098_H GCST90002381 Eosinophil counts 408,112 British individuals G 0.032717 1E-10 10 rs4149909 0.03992328 eosinophil count (EFO:0004842)
 PMID:32888494
GWAS651442_H GCST90002382 Eosinophil percentage of white cells 408,112 British individuals G 0.03272 5E-12 11.302 rs4149909 0.042866442 eosinophil percentage of leukocytes (EFO:0007991)
 PMID:32888494
GWAS702092_H GCST008871 Basal cell carcinoma 31,787 European ancestry cases, 619,351 European ancestry controls G 0.025624 1E-8 8 rs4149909 1.1494253 basal cell carcinoma (EFO:0004193)
 PMID:31174203
GWAS703063_H GCST008870 Keratinocyte cancer (MTAG) at least 18,538 European ancestry cases, at least 340,302 European ancestry controls G 0.032523 2E-9 8.699 rs4149909 1.16 keratinocyte carcinoma (EFO:0010176)
 PMID:31174203
GWAS1004154_H GCST90018953 Eosinophil counts 349,856 European ancestry individuals, 93,063 East Asian ancestry individuals G NR 6E-9 8.222 rs4149909 0.0286 eosinophil count (EFO:0004842)
 PMID:34594039
GWAS1005410_H GCST90292477 Systolic blood pressure 1,164,961 European ancestry individuals A 0.9667 2E-8 7.699 rs4149909 0.3230277 systolic blood pressure (EFO:0006335)
 PMID:33230300
None Available GCST90000062 Systolic blood pressure 810,865 European ancestry individuals A 0.9671 2E-8 7.699 rs4149909 0.4316023 systolic blood pressure (EFO:0006335)
 PMID:33230300
GWAS1011153_H GCST90328134 Basal cell carcinoma 49,905 European ancestry cases, 752,392 European ancestry controls, 626 Hispanic or Latin American cases, 9,842 Hispanic or Latin American controls G NR 4E-9 8.398 rs4149909 1.1313 basal cell carcinoma (EFO:0004193)
 PMID:38182794
GWAS1012092_H GCST90328132 Basal cell carcinoma 49,905 European ancestry cases, 752,392 European ancestry controls G NR 7E-9 8.155 rs4149909 1.1296 basal cell carcinoma (EFO:0004193)
 PMID:38182794
GWAS1029219_H GCST90134420 Uterine leiomyoma or breast cancer (pleiotropy) 35,474 European ancestry UL cases, 133,384 European ancestry BC cases, 381,294 European ancestry controls A NR 9E-15 14.046 rs4149909 N/A Uterine leiomyoma (HP:0000131)
breast carcinoma (EFO:0000305)
 PMID:35803233
None Available GCST90239856 Uterine leiomyomata 38,466 European ancestry cases, 329,437 European ancestry controls A NR 1E-8 8 rs4149909 0.87 Uterine leiomyoma (HP:0000131)
 PMID:36726022
GWAS1035441_H GCST90137411 Basal cell carcinoma (MTAG) 20,791 European ancestry cases, 286,893 European ancestry controls G NR 1E-26 26 rs4149909 N/A basal cell carcinoma (EFO:0004193)
 PMID:36496446
Database Acc Id Source(s)
GWAS Catalog GCST008871 GWAS Catalog
  GCST90239856 GWAS Catalog

RGD Curation Notes
Note Type Note Reference