References
References - curated
Region Genes in Region
RGD ID | Symbol | Name | Chr | Start | Stop | Species | 733345 | CELSR2 | cadherin EGF LAG seven-pass G-type receptor 2 | 1 | 109249539 | 109275751 | Human | 38665722 | LOC110121285 | VISTA enhancer hs2263 | 1 | 109274252 | 109276283 | Human | |
Position Markers
Peak: (rs12740374) |
|
QTLs in Region (GRCh38)
The following QTLs overlap with this region. | Full Report | CSV | TAB | Printer | Gviewer |
Additional Information
GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog | ||
The highlighted row represents the current QTL |
QTL | GWAS Catalog Study | Disease Trait | Study Size | Risk Allele | Risk Allele Frequency | P Value | P Value MLOG | Peak Marker | Reported Odds Ratio or Beta-coefficient | Ontology Accession | PubMed |
GWAS540734_H | GCST007140 | High density lipoprotein cholesterol levels | 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals | G | 0.782 | 3E-15 | 14.523 | rs12740374 | 0.037 | high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:29507422 |
GWAS540735_H | GCST007140 | High density lipoprotein cholesterol levels | 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals | G | NR | 5E-15 | 14.302 | rs12740374 | 0.034 | high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:29507422 |
GWAS543094_H | GCST90241384 | Hemojuvelin levels (HFE2.3332.57.1) | 3,301 European ancestry individuals | T | 0.223 | 1E-14 | 14 | rs12740374 | 0.23 | hemojuvelin measurement (EFO:0008148) |
PMID:29875488 |
GWAS543207_H | GCST90241203 | Four-jointed box protein 1 levels (FJX1.7921.65.3) | 3,301 European ancestry individuals | T | 0.223 | 2E-18 | 17.699 | rs12740374 | 0.26 | four-jointed box protein 1 measurement (EFO:0801605) |
PMID:29875488 |
GWAS544072_H | GCST90240591 | Carbonic anhydrase-related protein 10 levels (CA10.13666.222.3) | 3,301 European ancestry individuals | T | 0.223 | 2E-23 | 22.699 | rs12740374 | 0.3 | carbonic anhydrase-related protein 10 measurement (EFO:0020233) |
PMID:29875488 |
GWAS548116_H | GCST90085768 | Progranulin plasma levels | 400 French ancestry individuals | G | NR | 2E-24 | 23.699 | rs12740374 | 0.351 | progranulin measurement (EFO:0004625) |
PMID:35264221 |
GWAS550633_H | GCST90134520 | LDL cholesterol levels | 58,701 Korean ancestry individuals | T | NR | 2E-48 | 47.699 | rs12740374 | 5.77 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35884923 |
GWAS550976_H | GCST90134518 | Total cholesterol levels | 58,701 Korean ancestry individuals | T | NR | 3E-32 | 31.523 | rs12740374 | 5.15 | total cholesterol measurement (EFO:0004574) |
PMID:35884923 |
GWAS559826_H | GCST007141 | Low density lipoprotein cholesterol levels | 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals | G | 0.782 | 4E-202 | 201.398 | rs12740374 | 0.179 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:29507422 |
GWAS559827_H | GCST007141 | Low density lipoprotein cholesterol levels | 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals | G | 0.798 | 5E-29 | 28.302 | rs12740374 | 0.21 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:29507422 |
GWAS559828_H | GCST007141 | Low density lipoprotein cholesterol levels | 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals | G | 0.933 | 0.000001 | 6 | rs12740374 | 0.162 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:29507422 |
GWAS559829_H | GCST007141 | Low density lipoprotein cholesterol levels | 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals | G | 0.756 | 3E-14 | 13.523 | rs12740374 | 0.227 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:29507422 |
GWAS559830_H | GCST007141 | Low density lipoprotein cholesterol levels | 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals | G | NR | 2E-247 | 246.699 | rs12740374 | 0.183 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:29507422 |
GWAS564676_H | GCST009042 | Total cholesterol levels | 14,126 African ancestry individuals | G | 0.698 | 9E-17 | 16.046 | rs12740374 | 0.108598 | total cholesterol measurement (EFO:0004574) |
PMID:31675503 |
GWAS564680_H | GCST009043 | LDL cholesterol levels | 14,126 African ancestry individuals | G | 0.698 | 2E-26 | 25.699 | rs12740374 | 0.143343 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:31675503 |
GWAS577381_H | GCST010242 | HDL cholesterol levels | 403,943 European ancestry individuals | G | 0.778994 | 2E-36 | 35.699 | rs12740374 | 0.0288626 | high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:32203549 |
GWAS580179_H | GCST009368 | HDL cholesterol levels x long total sleep time interaction (2df test) | 2,933 African American long sleepers, 364 Chinese ancestry long sleepers, 112 Asian ancestry long sleepers, up to 7,870 European ancestry long sleepers, 1,038 Hispanic/Latino long sleepers, up to 11,975 African American controls, 1,449 Chinese ancestry controls, 454 Asian ancestry controls, at least 32,171 European ancestry controls, 4,091 Hispanic/Latino controls | ? | NR | 3E-9 | 8.523 | rs12740374 | 0.006751 | sleep duration (EFO:0005271) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:31719535 |
GWAS581532_H | GCST009366 | LDL cholesterol levels x long total sleep time interaction (2df test) | 2,913 African American long sleepers, 358 Chinese ancestry long sleepers, 110 Asian ancestry long sleepers, 7,583 European ancestry long sleepers, 1,036 Hispanic/Latino long sleepers, up to 11,862 African American controls, 1,432 Chinese ancestry controls, 444 Asian ancestry controls, at least 31,744 European ancestry controls, 4,066 Hispanic/Latino controls | ? | NR | 5E-136 | 135.302 | rs12740374 | 5.358 | sleep duration (EFO:0005271) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:31719535 |
GWAS591375_H | GCST90247838 | Group XIIB secretory phospholipase A2-like protein levels | 10,708 European ancestry individuals | T | 0.22 | 8E-193 | 192.097 | rs12740374 | 0.463 | group XIIB secretory phospholipase A2-like protein measurement (EFO:0801657) |
PMID:34648354 |
GWAS591511_H | GCST90247617 | Four-jointed box protein 1 levels | 10,708 European ancestry individuals | T | 0.22 | 2E-61 | 60.699 | rs12740374 | 0.259 | four-jointed box protein 1 measurement (EFO:0801605) |
PMID:34648354 |
GWAS596667_H | GCST010866 | Coronary artery disease | 25,892 Japanese ancestry cases, 95,342 European ancestry cases, 142,336 Japanese ancestry controls, 385,488 European ancestry controls | ? | NR | 1E-62 | 62 | rs12740374 | 0.106316 | coronary artery disease (EFO:0001645) |
PMID:33020668 |
GWAS606205_H | GCST004209 | Cholesterol, total | 19,259 British ancestry individuals from 6863 families. | T | 0.2288 | 8E-22 | 21.097 | rs12740374 | 0.12353132 | total cholesterol measurement (EFO:0004574) |
PMID:28270201 |
GWAS609393_H | GCST90246766 | Complement C1q tumor necrosis factor-related protein 1 levels | 10,708 European ancestry individuals | T | 0.22 | 2E-530 | 529.699 | rs12740374 | 0.725 | complement C1q tumor necrosis factor-related protein 1 measurement (EFO:0801493) |
PMID:34648354 |
GWAS619929_H | GCST90247801 | Granulins levels | 10,708 European ancestry individuals | T | 0.22 | 4E-864 | 863.398 | rs12740374 | 0.863 | granulins measurement (EFO:0008141) |
PMID:34648354 |
GWAS627167_H | GCST011365 | Myocardial infarction | 14,825 European ancestry cases, 44,000 European and unknown ancestry cases, 2,680 cases, 380,970 European ancestry controls, 123,504 European and unknown ancestry controls, 73,242 controls | G | 0.788431 | 8E-32 | 31.097 | rs12740374 | 1.11 | myocardial infarction (EFO:0000612) |
PMID:33532862 |
GWAS629924_H | GCST011741 | LDL cholesterol levels in HIV infection | 3,095 European ancestry individuals, 3,189 African American individuals | ? | NR | 1E-7 | 7 | rs12740374 | 0.15287153 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:33109212 |
None Available | GCST011741 | LDL cholesterol levels in HIV infection | 3,095 European ancestry individuals, 3,189 African American individuals | ? | NR | 0.000001 | 6 | rs12740374 | 0.14413212 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:33109212 |
GWAS630315_H | GCST011364 | Myocardial infarction | 14,825 European ancestry cases, 2,680 cases, 380,970 European ancestry controls, 73,242 controls | G | 0.777761 | 6E-18 | 17.222 | rs12740374 | 1.12 | myocardial infarction (EFO:0000612) |
PMID:33532862 |
GWAS633488_H | GCST008035 | High density lipoprotein cholesterol levels | 10,085 African American individuals, 17,751 Hispanic/Latino individuals, 2,378 Asian ancestry individuals, 1,912 Native Hawaiian ancestry individuals, 604 Native American ancestry individuals, 333 individuals | ? | NR | 0.000006 | 5.222 | rs12740374 | 0.6266499 | high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:31217584 |
GWAS636696_H | GCST007841 | Height | approximately 458,000 European ancestry individuals | ? | NR | 2E-14 | 13.699 | rs12740374 | N/A | body height (EFO:0004339) |
PMID:30595370 |
GWAS637121_H | GCST008037 | Low density lipoprotein cholesterol levels | 9,720 African American individuals, 17,373 Hispanic/Latino individuals, 2,316 Asian ancestry individuals, 1,900 Native Hawaiian ancestry individuals, 591 Native American ancestry individuals, 321 individuals | ? | NR | 8E-81 | 80.097 | rs12740374 | 7.2666 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:31217584 |
GWAS640505_H | GCST008045 | Total cholesterol levels | 10,137 African American individuals, 17,802 Hispanic/Latino individuals, 2,387 Asian ancestry individuals, 1,915 Native Hawaiian ancestry individuals, 604 Native American ancestry individuals, 340 individuals | ? | NR | 1E-65 | 65 | rs12740374 | 7.293991 | total cholesterol measurement (EFO:0004574) |
PMID:31217584 |
GWAS643915_H | GCST011347 | Low density lipoprotein cholesterol levels | 76,081 European ancestry individuals, 127,395 Japanese ancestry individuals | ? | NR | 7E-104 | 103.155 | rs12740374 | 0.1324 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:33339817 |
GWAS655819_H | GCST007441 | Total cholesterol levels | 6,949 Korean ancestry individuals | T | 0.059 | 4E-11 | 10.398 | rs12740374 | 8.3697 | total cholesterol measurement (EFO:0004574) |
PMID:30718733 |
GWAS656102_H | GCST007128 | Blood protein levels | 6861 European ancestry individuals | T | 0.215441066 | 9E-230 | 229.046 | rs12740374 | 0.727792 | blood protein measurement (EFO:0007937) |
PMID:30111768 |
GWAS656742_H | GCST007442 | Low density lipoprotein cholesterol levels | 6,949 Korean ancestry individuals | T | 0.059 | 3E-11 | 10.523 | rs12740374 | 0.0714 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:30718733 |
GWAS660576_H | GCST007924 | Medication use (antithrombotic agents) | 67,653 European ancestry cases, 85,986 European ancestry controls | T | 0.221168 | 3E-20 | 19.523 | rs12740374 | 0.07470976 | Antithrombotic agent use measurement (EFO:0009925) |
PMID:31015401 |
GWAS663330_H | GCST007931 | Medication use (HMG CoA reductase inhibitors) | 73,475 European ancestry cases, 216,910 European ancestry controls | T | 0.219778 | 2E-119 | 118.699 | rs12740374 | 0.15661827 | HMG CoA reductase inhibitor use measurement (EFO:0009932) |
PMID:31015401 |
GWAS669697_H | GCST001727 | Lipoprotein-associated phospholipase A2 activity and mass | 6,851 European ancestry individuals | T | 0.22 | 2E-22 | 21.699 | rs12740374 | 0.0344 | lipoprotein-associated phospholipase A(2) measurement (EFO:0004746) |
PMID:23118302 |
None Available | GCST90269668 | Triglycerides in medium HDL (UKB data field 23571) | 88,329 European ancestry individuals | T | 0.22076 | 4E-11 | 10.398 | rs12740374 | 0.0370026 | triglycerides in medium HDL measurement (EFO:0022321) |
PMID:36764567 |
GWAS672582_H | GCST90269685 | Triglycerides to total lipids in very large VLDL percentage (UKB data field 23588) | 87,620 European ancestry individuals | T | 0.220663 | 1E-24 | 24 | rs12740374 | 0.0566208 | triglycerides to total lipids in very large VLDL percentage (EFO:0022340) |
PMID:36764567 |
GWAS672905_H | GCST90269683 | Cholesteryl esters to total lipids in very large VLDL percentage (UKB data field 23586) | 87,620 European ancestry individuals | T | 0.220663 | 5E-22 | 21.302 | rs12740374 | 0.0528024 | cholesteryl esters to total lipids in very large VLDL percentage (EFO:0022258) |
PMID:36764567 |
GWAS673308_H | GCST90269705 | Triglycerides to total lipids in very small VLDL percentage (UKB data field 23608) | 88,329 European ancestry individuals | T | 0.22076 | 5E-18 | 17.302 | rs12740374 | 0.0470455 | triglycerides to total lipids in very small VLDL percentage (EFO:0022341) |
PMID:36764567 |
GWAS673629_H | GCST90269733 | Cholesteryl esters to total lipids in large HDL percentage (UKB data field 23636) | 88,329 European ancestry individuals | T | 0.22076 | 6E-17 | 16.222 | rs12740374 | 0.0457334 | cholesteryl esters to total lipids in large HDL percentage (EFO:0022248) |
PMID:36764567 |
GWAS674075_H | GCST90269704 | Free cholesterol to total lipids in very small VLDL percentage (UKB data field 23607) | 88,329 European ancestry individuals | T | 0.22076 | 4E-47 | 46.398 | rs12740374 | 0.0818507 | free cholesterol to total lipids in very small VLDL percentage (EFO:0022290) |
PMID:36764567 |
GWAS674191_H | GCST90269725 | Triglycerides to total lipids in small LDL percentage (UKB data field 23628) | 88,329 European ancestry individuals | T | 0.22076 | 7E-24 | 23.155 | rs12740374 | 0.0557225 | triglycerides to total lipids in small LDL percentage (EFO:0022337) |
PMID:36764567 |
GWAS674463_H | GCST90269713 | Cholesteryl esters to total lipids in large LDL percentage (UKB data field 23616) | 88,329 European ancestry individuals | T | 0.22076 | 3E-24 | 23.523 | rs12740374 | 0.0577086 | cholesteryl esters to total lipids in large LDL percentage (EFO:0022249) |
PMID:36764567 |
GWAS674731_H | GCST000975 | LDL cholesterol | 7,565 African American individuals | T | 0.25 | 9E-29 | 28.046 | rs12740374 | 0.1815 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:21347282 |
GWAS675052_H | GCST90269732 | Cholesterol to total lipids in large HDL percentage (UKB data field 23635) | 88,329 European ancestry individuals | T | 0.22076 | 9E-24 | 23.046 | rs12740374 | 0.054393 | cholesterol to total lipids in large HDL percentage (EFO:0022234) |
PMID:36764567 |
GWAS676430_H | GCST90276156 | Aortic stenosis | 13,765 European ancestry cases, 640,102 European ancestry controls | ? | NR | 2E-9 | 8.699 | rs12740374 | 0.92 | aortic stenosis (EFO:0000266) |
PMID:37038246 |
GWAS677099_H | GCST000287 | LDL cholesterol | 19,840 European ancestry individuals | T | 0.21 | 2E-42 | 41.699 | rs12740374 | 0.23 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:19060906 |
GWAS678295_H | GCST90269526 | Concentration of LDL particles (UKB data field 23429) | 88,329 European ancestry individuals | T | 0.22076 | 4E-97 | 96.398 | rs12740374 | 0.119047 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:36764567 |
GWAS678702_H | GCST90269502 | LDL cholesterol levels (UKB data field 23405) | 88,329 European ancestry individuals | T | 0.22076 | 2E-92 | 91.699 | rs12740374 | 0.115647 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:36764567 |
GWAS678751_H | GCST90269620 | Concentration of IDL particles (UKB data field 23523) | 88,329 European ancestry individuals | T | 0.22076 | 2E-63 | 62.699 | rs12740374 | 0.0946666 | intermediate density lipoprotein measurement (EFO:0008595) |
PMID:36764567 |
GWAS679374_H | GCST90269618 | Free cholesterol in very small VLDL (UKB data field 23521) | 88,329 European ancestry individuals | T | 0.22076 | 1E-50 | 50 | rs12740374 | 0.0834628 | free cholesterol in very small VLDL measurement (EFO:0022275) |
PMID:36764567 |
GWAS679398_H | GCST90269652 | Cholesteryl esters in very large HDL (UKB data field 23555) | 88,329 European ancestry individuals | T | 0.22076 | 3E-19 | 18.523 | rs12740374 | 0.0464537 | cholesteryl ester measurement (EFO:0010351) |
PMID:36764567 |
GWAS679496_H | GCST90269514 | Cholesteryl esters in LDL (UKB data field 23417) | 88,329 European ancestry individuals | T | 0.22076 | 4E-88 | 87.398 | rs12740374 | 0.113066 | cholesteryl ester measurement (EFO:0010351) |
PMID:36764567 |
GWAS679632_H | GCST90269529 | Average diameter for LDL particles (UKB data field 23432) | 88,329 European ancestry individuals | T | 0.22076 | 6E-23 | 22.222 | rs12740374 | 0.0546513 | low density lipoprotein particle size measurement (EFO:0008593) |
PMID:36764567 |
GWAS679718_H | GCST90269649 | Total lipids in very large HDL (UKB data field 23552) | 88,329 European ancestry individuals | T | 0.22076 | 2E-12 | 11.699 | rs12740374 | 0.0363951 | total lipids in very large HDL measurement (EFO:0022312) |
PMID:36764567 |
None Available | GCST90269616 | Cholesterol in very small VLDL (UKB data field 23519) | 88,329 European ancestry individuals | T | 0.22076 | 2E-48 | 47.699 | rs12740374 | 0.0808542 | cholesterol in very small VLDL measurement (EFO:0022231) |
PMID:36764567 |
GWAS680235_H | GCST90269621 | Total lipids in IDL (UKB data field 23524) | 88,329 European ancestry individuals | T | 0.22076 | 7E-67 | 66.155 | rs12740374 | 0.0952981 | total lipids in IDL (EFO:0022161) |
PMID:36764567 |
GWAS680500_H | GCST90269653 | Free cholesterol in very large HDL (UKB data field 23556) | 88,329 European ancestry individuals | T | 0.22076 | 1E-27 | 27 | rs12740374 | 0.0582147 | free cholesterol in very large HDL measurement (EFO:0022273) |
PMID:36764567 |
GWAS680992_H | GCST90269501 | Clinical LDL cholesterol levels (UKB data field 23404) | 88,329 European ancestry individuals | T | 0.22076 | 8E-91 | 90.097 | rs12740374 | 0.114538 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:36764567 |
GWAS681080_H | GCST90269651 | Cholesterol in very large HDL (UKB data field 23554) | 88,329 European ancestry individuals | T | 0.22076 | 1E-21 | 21 | rs12740374 | 0.0496235 | cholesterol in very large HDL measurement (EFO:0022229) |
PMID:36764567 |
GWAS681459_H | GCST90269516 | Total free cholesterol levels (UKB data field 23419) | 88,329 European ancestry individuals | T | 0.22076 | 3E-66 | 65.523 | rs12740374 | 0.0956838 | free cholesterol measurement (EFO:0008591) |
PMID:36764567 |
GWAS682196_H | GCST90269518 | Free cholesterol in LDL (UKB data field 23421) | 88,329 European ancestry individuals | T | 0.22076 | 3E-97 | 96.523 | rs12740374 | 0.118139 | free cholesterol in LDL measurement (EFO:0022266) |
PMID:36764567 |
GWAS682379_H | GCST90269617 | Cholesteryl esters in very small VLDL (UKB data field 23520) | 88,329 European ancestry individuals | T | 0.22076 | 5E-46 | 45.302 | rs12740374 | 0.0783171 | cholesteryl ester measurement (EFO:0010351) |
PMID:36764567 |
GWAS682540_H | GCST90269642 | Total lipids in small LDL (UKB data field 23545) | 88,329 European ancestry individuals | T | 0.22076 | 4E-106 | 105.398 | rs12740374 | 0.12456 | total lipids in small LDL (EFO:0022168) |
PMID:36764567 |
GWAS683127_H | GCST90269615 | Phospholipids in very small VLDL (UKB data field 23518) | 88,329 European ancestry individuals | T | 0.22076 | 3E-41 | 40.523 | rs12740374 | 0.0752281 | phospholipids in very small VLDL measurement (EFO:0022300) |
PMID:36764567 |
GWAS683468_H | GCST90269638 | Cholesteryl esters in medium LDL (UKB data field 23541) | 88,329 European ancestry individuals | T | 0.22076 | 2E-74 | 73.699 | rs12740374 | 0.104172 | cholesteryl ester measurement (EFO:0010351) |
PMID:36764567 |
GWAS683775_H | GCST90269639 | Free cholesterol in medium LDL (UKB data field 23542) | 88,329 European ancestry individuals | T | 0.22076 | 4E-101 | 100.398 | rs12740374 | 0.121496 | free cholesterol in medium LDL measurement (EFO:0022268) |
PMID:36764567 |
GWAS683913_H | GCST90269648 | Concentration of very large HDL particles (UKB data field 23551) | 88,329 European ancestry individuals | T | 0.22076 | 3E-22 | 21.523 | rs12740374 | 0.0502925 | high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:36764567 |
GWAS684193_H | GCST90269610 | Cholesteryl esters in small VLDL (UKB data field 23513) | 88,329 European ancestry individuals | T | 0.22076 | 9E-59 | 58.046 | rs12740374 | 0.0919408 | cholesteryl ester measurement (EFO:0010351) |
PMID:36764567 |
GWAS684464_H | GCST90269512 | Total esterified cholesterol levels (UKB data field 23415) | 88,329 European ancestry individuals | T | 0.22076 | 1E-61 | 61 | rs12740374 | 0.0912627 | esterified cholesterol measurement (EFO:0008589) |
PMID:36764567 |
GWAS684514_H | GCST90269609 | Cholesterol in small VLDL (UKB data field 23512) | 88,329 European ancestry individuals | T | 0.22076 | 2E-65 | 64.699 | rs12740374 | 0.0972029 | cholesterol in small VLDL measurement (EFO:0022228) |
PMID:36764567 |
GWAS684837_H | GCST90269646 | Free cholesterol in small LDL (UKB data field 23549) | 88,329 European ancestry individuals | T | 0.22076 | 5E-120 | 119.302 | rs12740374 | 0.132513 | free cholesterol in small LDL measurement (EFO:0022271) |
PMID:36764567 |
GWAS684932_H | GCST90269500 | VLDL cholesterol levels (UKB data field 23403) | 88,329 European ancestry individuals | T | 0.22076 | 2E-43 | 42.699 | rs12740374 | 0.0784764 | very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:36764567 |
GWAS685528_H | GCST90269498 | Total cholesterol minus HDL-C levels (UKB data field 23401) | 88,329 European ancestry individuals | T | 0.22076 | 5E-79 | 78.302 | rs12740374 | 0.10667 | total cholesterol measurement (EFO:0004574) |
PMID:36764567 |
GWAS685587_H | GCST90269614 | Total lipids in very small VLDL (UKB data field 23517) | 88,329 European ancestry individuals | T | 0.22076 | 4E-41 | 40.398 | rs12740374 | 0.0749313 | total lipids in very small VLDL measurement (EFO:0022156) |
PMID:36764567 |
GWAS685730_H | GCST90269611 | Free cholesterol in small VLDL (UKB data field 23514) | 88,329 European ancestry individuals | T | 0.22076 | 5E-75 | 74.302 | rs12740374 | 0.104402 | free cholesterol in small VLDL measurement (EFO:0022272) |
PMID:36764567 |
GWAS685745_H | GCST90269645 | Cholesteryl esters in small LDL (UKB data field 23548) | 88,329 European ancestry individuals | T | 0.22076 | 2E-83 | 82.699 | rs12740374 | 0.110317 | cholesteryl ester measurement (EFO:0010351) |
PMID:36764567 |
GWAS685820_H | GCST90269497 | Total cholesterol levels (UKB data field 23400) | 88,329 European ancestry individuals | T | 0.22076 | 1E-63 | 63 | rs12740374 | 0.0930472 | total cholesterol measurement (EFO:0004574) |
PMID:36764567 |
GWAS685958_H | GCST90269513 | Cholesteryl esters in VLDL (UKB data field 23416) | 88,329 European ancestry individuals | T | 0.22076 | 2E-51 | 50.699 | rs12740374 | 0.08589 | cholesteryl ester measurement (EFO:0010351) |
PMID:36764567 |
GWAS686187_H | GCST90269641 | Concentration of small LDL particles (UKB data field 23544) | 88,329 European ancestry individuals | T | 0.22076 | 1E-82 | 82 | rs12740374 | 0.109711 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:36764567 |
GWAS686500_H | GCST90269643 | Phospholipids in small LDL (UKB data field 23546) | 88,329 European ancestry individuals | T | 0.22076 | 1E-136 | 136 | rs12740374 | 0.141426 | phospholipids in small LDL measurement (EFO:0022297) |
PMID:36764567 |
GWAS686616_H | GCST90269644 | Cholesterol in small LDL (UKB data field 23547) | 88,329 European ancestry individuals | T | 0.22076 | 3E-98 | 97.523 | rs12740374 | 0.119963 | cholesterol in small LDL measurement (EFO:0022227) |
PMID:36764567 |
None Available | GCST90269499 | Remnant cholesterol (non-HDL, non-LDL -cholesterol) levels (UKB data field 23402) | 88,329 European ancestry individuals | T | 0.22076 | 2E-61 | 60.699 | rs12740374 | 0.0935721 | remnant cholesterol measurement (EFO:0010815) |
PMID:36764567 |
GWAS687094_H | GCST90269613 | Concentration of very small VLDL particles (UKB data field 23516) | 88,329 European ancestry individuals | T | 0.22076 | 1E-48 | 48 | rs12740374 | 0.0821809 | very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:36764567 |
None Available | GCST90269604 | Free cholesterol in medium VLDL (UKB data field 23507) | 88,329 European ancestry individuals | T | 0.22076 | 1E-63 | 63 | rs12740374 | 0.0958509 | free cholesterol in medium VLDL measurement (EFO:0022269) |
PMID:36764567 |
GWAS687393_H | GCST90269602 | Cholesterol in medium VLDL (UKB data field 23505) | 88,329 European ancestry individuals | T | 0.22076 | 2E-78 | 77.699 | rs12740374 | 0.106571 | cholesterol in medium VLDL measurement (EFO:0022225) |
PMID:36764567 |
GWAS687491_H | GCST90269535 | Sphingomyelins levels (UKB data field 23438) | 88,268 European ancestry individuals | T | 0.220748 | 3E-50 | 49.523 | rs12740374 | 0.0796037 | sphingomyelin measurement (EFO:0010118) |
PMID:36764567 |
GWAS687546_H | GCST90269634 | Concentration of medium LDL particles (UKB data field 23537) | 88,329 European ancestry individuals | T | 0.22076 | 4E-72 | 71.398 | rs12740374 | 0.102543 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:36764567 |
GWAS687811_H | GCST90269632 | Free cholesterol in large LDL (UKB data field 23535) | 88,329 European ancestry individuals | T | 0.22076 | 2E-89 | 88.699 | rs12740374 | 0.112439 | free cholesterol in large LDL measurement (EFO:0022176) |
PMID:36764567 |
GWAS687871_H | GCST90269522 | Total lipids in LDL (UKB data field 23425) | 88,329 European ancestry individuals | T | 0.22076 | 3E-93 | 92.523 | rs12740374 | 0.116284 | total lipids in LDL measurement (EFO:0022308) |
PMID:36764567 |
GWAS687923_H | GCST90269601 | Phospholipids in medium VLDL (UKB data field 23504) | 88,329 European ancestry individuals | T | 0.22076 | 6E-55 | 54.222 | rs12740374 | 0.0887823 | phospholipids in medium VLDL measurement (EFO:0022154) |
PMID:36764567 |
GWAS687930_H | GCST90269631 | Cholesteryl esters in large LDL (UKB data field 23534) | 88,329 European ancestry individuals | T | 0.22076 | 3E-90 | 89.523 | rs12740374 | 0.113719 | cholesteryl ester measurement (EFO:0010351) |
PMID:36764567 |
GWAS688054_H | GCST90269637 | Cholesterol in medium LDL (UKB data field 23540) | 88,329 European ancestry individuals | T | 0.22076 | 3E-84 | 83.523 | rs12740374 | 0.110941 | cholesterol in medium LDL measurement (EFO:0022224) |
PMID:36764567 |
GWAS688182_H | GCST90269630 | Cholesterol in large LDL (UKB data field 23533) | 88,329 European ancestry individuals | T | 0.22076 | 3E-91 | 90.523 | rs12740374 | 0.114191 | cholesterol in large LDL measurement (EFO:0021901) |
PMID:36764567 |
GWAS688527_H | GCST90269608 | Phospholipids in small VLDL (UKB data field 23511) | 88,329 European ancestry individuals | T | 0.22076 | 8E-60 | 59.097 | rs12740374 | 0.0926959 | phospholipids in small VLDL measurement (EFO:0022146) |
PMID:36764567 |
GWAS689068_H | GCST90269520 | Total lipids in lipoprotein particles (UKB data field 23423) | 88,329 European ancestry individuals | T | 0.22076 | 3E-38 | 37.523 | rs12740374 | 0.0723811 | total lipids in lipoprotein particles measurement (EFO:0022309) |
PMID:36764567 |
GWAS689091_H | GCST90269543 | Polyunsaturated fatty acids levels (UKB data field 23446) | 88,268 European ancestry individuals | T | 0.220748 | 1E-25 | 25 | rs12740374 | 0.0580204 | polyunsaturated fatty acid measurement (EFO:0010733) |
PMID:36764567 |
GWAS689122_H | GCST90269599 | Concentration of medium VLDL particles (UKB data field 23502) | 88,329 European ancestry individuals | T | 0.22076 | 5E-52 | 51.302 | rs12740374 | 0.0862277 | very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:36764567 |
GWAS689344_H | GCST90269600 | Total lipids in medium VLDL (UKB data field 23503) | 88,329 European ancestry individuals | T | 0.22076 | 1E-40 | 40 | rs12740374 | 0.0754908 | total lipids in medium VLDL (EFO:0022153) |
PMID:36764567 |
None Available | GCST90269636 | Phospholipids in medium LDL (UKB data field 23539) | 88,329 European ancestry individuals | T | 0.22076 | 3E-93 | 92.523 | rs12740374 | 0.116833 | phospholipids in medium LDL measurement (EFO:0022183) |
PMID:36764567 |
GWAS690243_H | GCST90269628 | Total lipids in large LDL (UKB data field 23531) | 88,329 European ancestry individuals | T | 0.22076 | 9E-91 | 90.046 | rs12740374 | 0.114022 | total lipids in large LDL (EFO:0022163) |
PMID:36764567 |
None Available | GCST90269603 | Cholesteryl esters in medium VLDL (UKB data field 23506) | 88,329 European ancestry individuals | T | 0.22076 | 2E-83 | 82.699 | rs12740374 | 0.109314 | cholesteryl ester measurement (EFO:0010351) |
PMID:36764567 |
GWAS690583_H | GCST90269635 | Total lipids in medium LDL (UKB data field 23538) | 88,329 European ancestry individuals | T | 0.22076 | 5E-86 | 85.302 | rs12740374 | 0.112115 | total lipids in medium LDL (EFO:0022180) |
PMID:36764567 |
GWAS690673_H | GCST90250902 | Medication use for hyperlipidemia (number of purchases) | 567,671 European ancestry individuals | ? | NR | 7E-206 | 205.155 | rs12740374 | 0.045946 | antihyperlipidemic drug use measurement (EFO:0803367) |
PMID:36653479 |
GWAS690728_H | GCST90269627 | Concentration of large LDL particles (UKB data field 23530) | 88,329 European ancestry individuals | T | 0.22076 | 4E-105 | 104.398 | rs12740374 | 0.123627 | concentration of large LDL particles measurement (EFO:0022160) |
PMID:36764567 |
GWAS690958_H | GCST90269629 | Phospholipids in large LDL (UKB data field 23532) | 88,329 European ancestry individuals | T | 0.22076 | 2E-84 | 83.699 | rs12740374 | 0.110116 | phospholipids in large LDL measurement (EFO:0022174) |
PMID:36764567 |
GWAS694258_H | GCST90302113 | Phospholipids to total lipids ratio in small VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2226 | 4E-31 | 30.398 | rs12740374 | 0.0547 | very low density lipoprotein cholesterol measurement (EFO:0008317) phospholipids:total lipids ratio (EFO:0020946) |
PMID:38448586 |
GWAS698553_H | GCST90302115 | Triglycerides to total lipids ratio in small VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2225 | 8E-31 | 30.097 | rs12740374 | 0.0543 | triglycerides:total lipids ratio (EFO:0020947) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:38448586 |
GWAS708044_H | GCST010241 | Apolipoprotein A1 levels | 393,193 European ancestry individuals | G | 0.779088 | 1E-78 | 78 | rs12740374 | 0.0443235 | apolipoprotein A 1 measurement (EFO:0004614) |
PMID:32203549 |
None Available | GCST90012000 | E-selectin levels | 21,758 European ancestry individuals | T | 0.22 | 2E-18 | 17.699 | rs12740374 | 0.0815 | e-selectin measurement (EFO:0004575) |
PMID:33067605 |
GWAS716094_H | GCST005194 | Coronary artery disease | 34,541 cases, 261,984 controls | T | 0.219 | 2E-57 | 56.699 | rs12740374 | 0.124 | coronary artery disease (EFO:0001645) |
PMID:29212778 |
None Available | GCST90302161 | Triglycerides to total lipids ratio in very small VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2228 | 2E-22 | 21.699 | rs12740374 | 0.0458 | triglycerides:total lipids ratio (EFO:0020947) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:38448586 |
GWAS725669_H | GCST90269682 | Cholesterol to total lipids in very large VLDL percentage (UKB data field 23585) | 87,620 European ancestry individuals | T | 0.220663 | 1E-20 | 20 | rs12740374 | 0.0510047 | cholesterol to total lipids in very large VLDL percentage (EFO:0022244) |
PMID:36764567 |
GWAS726855_H | GCST90314082 | CLEC14A/TNFRSF21 protein level ratio | 43,509 European ancestry individuals | ? | NR | 2E-50 | 49.699 | rs12740374 | 0.116874 | blood protein measurement (EFO:0007937) |
PMID:38412862 |
None Available | GCST90269710 | Triglycerides to total lipids in IDL percentage (UKB data field 23613) | 88,329 European ancestry individuals | T | 0.22076 | 3E-14 | 13.523 | rs12740374 | 0.0418932 | triglycerides to total lipids in IDL percentage (EFO:0022329) |
PMID:36764567 |
GWAS728246_H | GCST90269697 | Cholesterol to total lipids in small VLDL percentage (UKB data field 23600) | 88,329 European ancestry individuals | T | 0.22076 | 5E-48 | 47.302 | rs12740374 | 0.0810868 | cholesterol to total lipids in small VLDL percentage (EFO:0022242) |
PMID:36764567 |
None Available | GCST90269699 | Free cholesterol to total lipids in small VLDL percentage (UKB data field 23602) | 88,329 European ancestry individuals | T | 0.22076 | 3E-41 | 40.523 | rs12740374 | 0.0734164 | free cholesterol to total lipids in small VLDL percentage (EFO:0022287) |
PMID:36764567 |
None Available | GCST90269700 | Triglycerides to total lipids in small VLDL percentage (UKB data field 23603) | 88,329 European ancestry individuals | T | 0.22076 | 5E-48 | 47.302 | rs12740374 | 0.0806298 | triglycerides to total lipids in small VLDL percentage (EFO:0022338) |
PMID:36764567 |
GWAS733057_H | GCST90269731 | Phospholipids to total lipids in large HDL percentage (UKB data field 23634) | 88,329 European ancestry individuals | T | 0.22076 | 2E-58 | 57.699 | rs12740374 | 0.0891742 | phospholipids:total lipids ratio (EFO:0020946) |
PMID:36764567 |
GWAS733802_H | GCST90302033 | Cholesterol esters in medium HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2224 | 7E-18 | 17.155 | rs12740374 | 0.0411 | esterified cholesterol measurement (EFO:0008589) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
GWAS733963_H | GCST90269736 | Phospholipids to total lipids in medium HDL percentage (UKB data field 23639) | 88,329 European ancestry individuals | T | 0.22076 | 1E-16 | 16 | rs12740374 | 0.0450517 | phospholipids:total lipids ratio (EFO:0020946) |
PMID:36764567 |
GWAS734484_H | GCST90302037 | Total lipids in medium HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2226 | 2E-15 | 14.699 | rs12740374 | 0.0375 | total lipids in medium HDL measurement (EFO:0022310) |
PMID:38448586 |
None Available | GCST90301986 | Triglycerides to total lipids ratio in IDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.223 | 7E-24 | 23.155 | rs12740374 | 0.0472 | triglycerides:total lipids ratio (EFO:0020947) intermediate density lipoprotein measurement (EFO:0008595) |
PMID:38448586 |
GWAS735780_H | GCST90269695 | Triglycerides to total lipids in medium VLDL percentage (UKB data field 23598) | 88,329 European ancestry individuals | T | 0.22076 | 2E-34 | 33.699 | rs12740374 | 0.0663002 | triglycerides to total lipids in medium VLDL percentage (EFO:0022335) |
PMID:36764567 |
None Available | GCST90302030 | Triglycerides to total lipids ratio in large VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2227 | 2E-26 | 25.699 | rs12740374 | 0.0523 | triglycerides:total lipids ratio (EFO:0020947) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:38448586 |
GWAS737436_H | GCST90269694 | Free cholesterol to total lipids in medium VLDL percentage (UKB data field 23597) | 88,329 European ancestry individuals | T | 0.22076 | 2E-38 | 37.699 | rs12740374 | 0.070797 | free cholesterol to total lipids in medium VLDL percentage (EFO:0022284) |
PMID:36764567 |
None Available | GCST90269696 | Phospholipids to total lipids in small VLDL percentage (UKB data field 23599) | 88,329 European ancestry individuals | T | 0.22076 | 2E-43 | 42.699 | rs12740374 | 0.0756845 | phospholipids:total lipids ratio (EFO:0020946) |
PMID:36764567 |
GWAS738495_H | GCST90301997 | Cholesterol esters in large HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2225 | 1E-9 | 9 | rs12740374 | 0.0289 | cholesterol esters in large HDL measurement (EFO:0022159) |
PMID:38448586 |
GWAS739376_H | GCST90269741 | Phospholipids to total lipids in small HDL percentage (UKB data field 23644) | 88,329 European ancestry individuals | T | 0.22076 | 6E-92 | 91.222 | rs12740374 | 0.11185 | phospholipids:total lipids ratio (EFO:0020946) |
PMID:36764567 |
None Available | GCST007143 | Total cholesterol levels | 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals | G | 0.756 | 4E-11 | 10.398 | rs12740374 | 0.196 | total cholesterol measurement (EFO:0004574) |
PMID:29507422 |
GWAS739378_H | GCST007143 | Total cholesterol levels | 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals | G | NR | 2E-168 | 167.699 | rs12740374 | 0.148 | total cholesterol measurement (EFO:0004574) |
PMID:29507422 |
None Available | GCST90302031 | Total cholesterol levels in medium HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2224 | 2E-15 | 14.699 | rs12740374 | 0.0378 | total cholesterol measurement (EFO:0004574) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
GWAS739948_H | GCST007143 | Total cholesterol levels | 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals | G | 0.782 | 9E-135 | 134.046 | rs12740374 | 0.143 | total cholesterol measurement (EFO:0004574) |
PMID:29507422 |
GWAS739949_H | GCST007143 | Total cholesterol levels | 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals | G | 0.798 | 5E-24 | 23.302 | rs12740374 | 0.189 | total cholesterol measurement (EFO:0004574) |
PMID:29507422 |
GWAS740189_H | GCST90245434 | Stearoyl sphingomyelin (d18:1/18:0) levels | 14,296 European ancestry individuals | T | 0.2161 | 1E-11 | 11 | rs12740374 | 0.082127124 | stearoyl sphingomyelin (d18:1/18:0) measurement (EFO:0800611) |
PMID:36357675 |
GWAS740914_H | GCST008593 | Low density lipoprotein cholesterol levels | 11,103 Hispanic or Latin American ancestry individuals | ? | NR | 1E-36 | 36 | rs12740374 | 0.205 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:31393916 |
GWAS741180_H | GCST008594 | Total cholesterol levels | 11,103 Hispanic or Latin American ancestry individuals | ? | NR | 1E-29 | 29 | rs12740374 | 0.17 | total cholesterol measurement (EFO:0004574) |
PMID:31393916 |
GWAS741449_H | GCST90269742 | Cholesterol to total lipids in small HDL percentage (UKB data field 23645) | 88,329 European ancestry individuals | T | 0.22076 | 9E-37 | 36.046 | rs12740374 | 0.0711223 | cholesterol to total lipids in small HDL percentage (EFO:0022240) |
PMID:36764567 |
GWAS741641_H | GCST90269715 | Triglycerides to total lipids in large LDL percentage (UKB data field 23618) | 88,329 European ancestry individuals | T | 0.22076 | 5E-17 | 16.302 | rs12740374 | 0.0466006 | triglycerides to total lipids in large LDL percentage (EFO:0022331) |
PMID:36764567 |
GWAS742676_H | GCST90269714 | Free cholesterol to total lipids in large LDL percentage (UKB data field 23617) | 88,329 European ancestry individuals | T | 0.22076 | 9E-10 | 9.046 | rs12740374 | 0.0334679 | free cholesterol to total lipids in large LDL percentage (EFO:0022280) |
PMID:36764567 |
GWAS743531_H | GCST90269734 | Free cholesterol to total lipids in large HDL percentage (UKB data field 23637) | 88,329 European ancestry individuals | T | 0.22076 | 6E-52 | 51.222 | rs12740374 | 0.0807656 | free cholesterol to total lipids in large HDL percentage (EFO:0022279) |
PMID:36764567 |
GWAS744630_H | GCST90269728 | Cholesteryl esters to total lipids in very large HDL percentage (UKB data field 23631) | 88,307 European ancestry individuals | T | 0.220747 | 3E-28 | 27.523 | rs12740374 | 0.0623038 | cholesteryl esters to total lipids in very large HDL percentage (EFO:0022257) |
PMID:36764567 |
GWAS745543_H | GCST90269744 | Free cholesterol to total lipids in small HDL percentage (UKB data field 23647) | 88,329 European ancestry individuals | T | 0.22076 | 7E-96 | 95.155 | rs12740374 | 0.113081 | free cholesterol to total lipids in small HDL percentage (EFO:0022285) |
PMID:36764567 |
None Available | GCST90269743 | Cholesteryl esters to total lipids in small HDL percentage (UKB data field 23646) | 88,329 European ancestry individuals | T | 0.22076 | 2E-14 | 13.699 | rs12740374 | 0.0428559 | cholesteryl esters to total lipids in small HDL percentage (EFO:0022254) |
PMID:36764567 |
GWAS746211_H | GCST90269691 | Phospholipids to total lipids in medium VLDL percentage (UKB data field 23594) | 88,329 European ancestry individuals | T | 0.22076 | 7E-46 | 45.155 | rs12740374 | 0.0780635 | phospholipids:total lipids ratio (EFO:0020946) |
PMID:36764567 |
None Available | GCST90269693 | Cholesteryl esters to total lipids in medium VLDL percentage (UKB data field 23596) | 88,329 European ancestry individuals | T | 0.22076 | 1E-27 | 27 | rs12740374 | 0.0584798 | cholesteryl esters to total lipids in medium VLDL percentage (EFO:0022253) |
PMID:36764567 |
GWAS746957_H | GCST90269692 | Cholesterol to total lipids in medium VLDL percentage (UKB data field 23595) | 88,329 European ancestry individuals | T | 0.22076 | 2E-30 | 29.699 | rs12740374 | 0.0619211 | cholesterol to total lipids in medium VLDL percentage (EFO:0022239) |
PMID:36764567 |
GWAS747218_H | GCST90269702 | Cholesterol to total lipids in very small VLDL percentage (UKB data field 23605) | 88,329 European ancestry individuals | T | 0.22076 | 2E-13 | 12.699 | rs12740374 | 0.0400608 | cholesterol to total lipids in very small VLDL percentage (EFO:0022245) |
PMID:36764567 |
GWAS749016_H | GCST90269712 | Cholesterol to total lipids in large LDL percentage (UKB data field 23615) | 88,329 European ancestry individuals | T | 0.22076 | 9E-38 | 37.046 | rs12740374 | 0.0711314 | cholesterol to total lipids in large LDL percentage (EFO:0022235) |
PMID:36764567 |
GWAS749094_H | GCST90269724 | Free cholesterol to total lipids in small LDL percentage (UKB data field 23627) | 88,329 European ancestry individuals | T | 0.22076 | 3E-17 | 16.523 | rs12740374 | 0.0466475 | free cholesterol to total lipids in small LDL percentage (EFO:0022286) |
PMID:36764567 |
None Available | GCST90269720 | Triglycerides to total lipids in medium LDL percentage (UKB data field 23623) | 88,329 European ancestry individuals | T | 0.22076 | 3E-19 | 18.523 | rs12740374 | 0.0501509 | triglycerides to total lipids in medium LDL percentage (EFO:0022334) |
PMID:36764567 |
None Available | GCST007072 | Cardiovascular disease | approximately 459,000 European ancestry individuals | ? | NR | 5E-24 | 23.302 | rs12740374 | N/A | cardiovascular disease (EFO:0000319) |
PMID:30595370 |
GWAS752697_H | GCST90269739 | Free cholesterol to total lipids in medium HDL percentage (UKB data field 23642) | 88,329 European ancestry individuals | T | 0.22076 | 4E-12 | 11.398 | rs12740374 | 0.0354236 | free cholesterol to total lipids in medium HDL percentage (EFO:0022282) |
PMID:36764567 |
None Available | GCST90309350 | Coronary artery disease (confirmatory factor analysis Factor 16) | 360,021 European ancestry individuals | ? | NR | 3E-40 | 39.523 | rs12740374 | N/A | coronary artery disease (EFO:0001645) |
PMID:38965376 |
GWAS756969_H | GCST90269508 | Total phospholipids in lipoprotein particles (UKB data field 23411) | 88,329 European ancestry individuals | T | 0.22076 | 5E-20 | 19.302 | rs12740374 | 0.0496801 | total phospholipids in lipoprotein particles measurement (EFO:0022315) |
PMID:36764567 |
GWAS758852_H | GCST90269510 | Phospholipids in LDL (UKB data field 23413) | 88,329 European ancestry individuals | T | 0.22076 | 4E-96 | 95.398 | rs12740374 | 0.118248 | phospholipids in LDL measurement (EFO:0022294) |
PMID:36764567 |
GWAS759100_H | GCST90302018 | Triglycerides to total lipids ratio in large LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.223 | 6E-25 | 24.222 | rs12740374 | 0.0484 | triglycerides:total lipids ratio (EFO:0020947) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:38448586 |
GWAS760176_H | GCST90269538 | Apolipoprotein B to apolipoprotein A1 ratio (UKB data field 23441) | 88,329 European ancestry individuals | T | 0.22076 | 1E-85 | 85 | rs12740374 | 0.110131 | apolipoprotein B to apolipoprotein A1 ratio (EFO:0021897) |
PMID:36764567 |
GWAS760368_H | GCST90302038 | Concentration of medium HDL particles | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2226 | 1E-15 | 15 | rs12740374 | 0.0377 | high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
GWAS761739_H | GCST90315242 | JAM2/TNFRSF21 protein level ratio | 43,509 European ancestry individuals | ? | NR | 2E-45 | 44.699 | rs12740374 | 0.112503 | blood protein measurement (EFO:0007937) |
PMID:38412862 |
GWAS762271_H | GCST90269536 | Apolipoprotein B levels (UKB data field 23439) | 88,329 European ancestry individuals | T | 0.22076 | 7E-88 | 87.155 | rs12740374 | 0.113059 | apolipoprotein B measurement (EFO:0004615) |
PMID:36764567 |
GWAS764492_H | GCST90269625 | Free cholesterol in IDL (UKB data field 23528) | 88,329 European ancestry individuals | T | 0.22076 | 4E-70 | 69.398 | rs12740374 | 0.0978585 | free cholesterol in IDL measurement (EFO:0022181) |
PMID:36764567 |
None Available | GCST90302039 | Phospholipids in medium HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2226 | 2E-15 | 14.699 | rs12740374 | 0.0374 | phospholipids in medium HDL measurement (EFO:0022295) |
PMID:38448586 |
GWAS764868_H | GCST90269624 | Cholesteryl esters in IDL (UKB data field 23527) | 88,329 European ancestry individuals | T | 0.22076 | 4E-59 | 58.398 | rs12740374 | 0.0893903 | cholesteryl ester measurement (EFO:0010351) |
PMID:36764567 |
None Available | GCST90002397 | Mean spheric corpuscular volume | 408,112 British individuals | T | 0.221719 | 7E-18 | 17.155 | rs12740374 | 0.022831036 | mean corpuscular volume (EFO:0004526) |
PMID:32888494 |
None Available | GCST90269623 | Cholesterol in IDL (UKB data field 23526) | 88,329 European ancestry individuals | T | 0.22076 | 1E-62 | 62 | rs12740374 | 0.092147 | cholesterol in IDL measurement (EFO:0021899) |
PMID:36764567 |
GWAS768169_H | GCST90269622 | Phospholipids in IDL (UKB data field 23525) | 88,329 European ancestry individuals | T | 0.22076 | 1E-73 | 73 | rs12740374 | 0.10001 | phospholipids in IDL measurement (EFO:0022164) |
PMID:36764567 |
GWAS771130_H | GCST90302083 | Free cholesterol in small HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2226 | 3E-33 | 32.523 | rs12740374 | 0.0564 | free cholesterol in small HDL measurement (EFO:0022270) |
PMID:38448586 |
GWAS771150_H | GCST90302087 | Phospholipids in small HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2227 | 1E-68 | 68 | rs12740374 | 0.0831 | phospholipids in small HDL measurement (EFO:0022296) |
PMID:38448586 |
GWAS771890_H | GCST90132304 | Coronary artery disease | 27,021 African American or Afro-Caribbean cases, 102,305 African American or Afro-Caribbean controls | ? | NR | 0.000003 | 5.523 | rs12740374 | 0.0547 | coronary artery disease (EFO:0001645) |
PMID:35915156 |
None Available | GCST90132303 | Coronary artery disease | 12,117 Hispanic or Latin American cases, 44,853 Hispanic or Latin American controls | ? | NR | 0.000001 | 6 | rs12740374 | 0.0918 | coronary artery disease (EFO:0001645) |
PMID:35915156 |
GWAS773870_H | GCST90302068 | Triglycerides to total lipids ratio in medium VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2229 | 3E-40 | 39.523 | rs12740374 | 0.0621 | triglycerides:total lipids ratio (EFO:0020947) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:38448586 |
None Available | GCST90302054 | Triglycerides to total lipids ratio in medium LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2227 | 1E-16 | 16 | rs12740374 | 0.039 | triglycerides:total lipids ratio (EFO:0020947) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:38448586 |
GWAS791756_H | GCST90302102 | Triglycerides to total lipids ratio in small LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2227 | 1E-13 | 13 | rs12740374 | 0.035 | triglycerides:total lipids ratio (EFO:0020947) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:38448586 |
None Available | GCST90309362 | Diabetes (confirmatory factor analysis Factor 28) | 360,514 European ancestry individuals | ? | NR | 4E-15 | 14.398 | rs12740374 | N/A | diabetes mellitus (EFO:0000400) |
PMID:38965376 |
GWAS796934_H | GCST90302149 | Triglycerides to total lipids ratio in very large VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 110,896 European ancestry individuals | T | 0.2231 | 2E-19 | 18.699 | rs12740374 | 0.0466 | triglycerides:total lipids ratio (EFO:0020947) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:38448586 |
GWAS814435_H | GCST90092849 | Free cholesterol to total lipids ratio in large HDL | 115,082 European ancestry individuals | G | 0.778936 | 2E-69 | 68.699 | rs12740374 | 0.081325 | free cholesterol:total lipids ratio (EFO:0020945) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
GWAS815084_H | GCST90000025 | Appendicular lean mass | 450,243 European ancestry individuals | T | 0.2214 | 2E-10 | 9.699 | rs12740374 | 0.015 | appendicular lean mass (EFO:0004980) |
PMID:33097823 |
GWAS816953_H | GCST90010851 | Sphingomyeline C16:0 levels | 31,023 Caucasian ancestry individuals | G | 0.7827 | 9E-27 | 26.046 | rs12740374 | 10.715 | sphingomyelin measurement (EFO:0010118) |
PMID:33414548 |
GWAS817197_H | GCST90010853 | Sphingomyeline C18:0 levels | 31,120 Caucasian ancestry individuals | G | 0.7803 | 4E-17 | 16.398 | rs12740374 | 8.401 | sphingomyelin measurement (EFO:0010118) |
PMID:33414548 |
GWAS818305_H | GCST90315813 | SCARF2/TNFRSF21 protein level ratio | 43,509 European ancestry individuals | ? | NR | 3E-46 | 45.523 | rs12740374 | 0.107388 | blood protein measurement (EFO:0007937) |
PMID:38412862 |
GWAS819569_H | GCST90038468 | Abdominal aortic aneurysm | 1,363 European, Indian, Caribbean, African ancestry cases, 27,260 European, Indian, Caribbean, African ancestry controls | ? | NR | 2E-7 | 6.699 | rs12740374 | 0.766762 | Abdominal Aortic Aneurysm (EFO:0004214) |
PMID:34469433 |
GWAS821779_H | GCST90315167 | IL6ST/MARCO protein level ratio | 43,509 European ancestry individuals | ? | NR | 4E-83 | 82.398 | rs12740374 | 0.157899 | blood protein measurement (EFO:0007937) |
PMID:38412862 |
GWAS830468_H | GCST90140948 | Total cholesterol levels | 22,000 Pakistani and Bangladeshi ancestry individuals | T | 0.26 | 8E-28 | 27.097 | rs12740374 | 0.14 | total cholesterol measurement (EFO:0004574) |
PMID:35945198 |
GWAS833558_H | GCST90132314 | Coronary artery disease | 181,522 European ancestry, unknown cases, 984,168 European ancestry, unknown controls | T | 0.216 | 1E-57 | 57 | rs12740374 | 0.909 | coronary artery disease (EFO:0001645) |
PMID:36474045 |
GWAS834034_H | GCST90237781 | Granulins level in Chronic kidney disease with hypertension and no diabetes (4992_49) | 466 African American individuals | T | 0.24 | 6E-16 | 15.222 | rs12740374 | 0.59 | granulins measurement (EFO:0008141) |
PMID:35870639 |
GWAS834649_H | GCST90092863 | Concentration of large LDL particles | 115,082 European ancestry individuals | G | 0.778936 | 6E-143 | 142.222 | rs12740374 | 0.125952 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
GWAS835396_H | GCST90092885 | Free cholesterol levels in LDL | 115,082 European ancestry individuals | G | 0.778936 | 5E-132 | 131.302 | rs12740374 | 0.1202 | free cholesterol measurement (EFO:0008591) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
GWAS836330_H | GCST90092858 | Cholesteryl ester levels in large LDL | 115,082 European ancestry individuals | G | 0.778936 | 4E-120 | 119.398 | rs12740374 | 0.114708 | cholesteryl ester measurement (EFO:0010351) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
GWAS837699_H | GCST90092862 | Total lipid levels in large LDL | 115,082 European ancestry individuals | G | 0.778936 | 2E-121 | 120.699 | rs12740374 | 0.115226 | low density lipoprotein cholesterol measurement (EFO:0004611) lipid measurement (EFO:0004529) |
PMID:35213538 |
GWAS837955_H | GCST90092861 | Free cholesterol to total lipids ratio in large LDL | 115,082 European ancestry individuals | G | 0.778936 | 3E-13 | 12.523 | rs12740374 | 0.0344208 | low density lipoprotein cholesterol measurement (EFO:0004611) free cholesterol:total lipids ratio (EFO:0020945) |
PMID:35213538 |
GWAS838300_H | GCST90092857 | Cholesterol to total lipids ratio in large LDL | 115,082 European ancestry individuals | G | 0.778936 | 3E-49 | 48.523 | rs12740374 | 0.0710724 | cholesterol:total lipids ratio (EFO:0020943) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
GWAS838975_H | GCST90018877 | Myocardial infarction | 20,917 European ancestry cases, 440,906 European ancestry controls, 14,992 East Asian ancestry cases, 146,214 East Asian ancestry controls | T | NR | 3E-23 | 22.523 | rs12740374 | 0.1203 | myocardial infarction (EFO:0000612) |
PMID:34594039 |
GWAS838986_H | GCST90092884 | Cholesteryl ester levels in LDL | 115,082 European ancestry individuals | G | 0.778936 | 5E-118 | 117.302 | rs12740374 | 0.114407 | cholesteryl ester measurement (EFO:0010351) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
GWAS839710_H | GCST90092867 | Triglycerides to total lipids ratio in large LDL | 115,082 European ancestry individuals | G | 0.778936 | 1E-23 | 23 | rs12740374 | 0.048419 | triglycerides:total lipids ratio (EFO:0020947) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
GWAS840953_H | GCST90092853 | Phospholipids to total lipids ratio in large HDL | 115,082 European ancestry individuals | G | 0.778936 | 2E-76 | 75.699 | rs12740374 | 0.0887005 | phospholipids:total lipids ratio (EFO:0020946) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
GWAS841291_H | GCST90092864 | Phospholipid levels in large LDL | 115,082 European ancestry individuals | G | 0.778936 | 2E-114 | 113.699 | rs12740374 | 0.112167 | low density lipoprotein cholesterol measurement (EFO:0004611) phospholipid measurement (EFO:0004639) |
PMID:35213538 |
GWAS843360_H | GCST90092856 | Cholesterol levels in large LDL | 115,082 European ancestry individuals | G | 0.778936 | 5E-122 | 121.302 | rs12740374 | 0.1154 | total cholesterol measurement (EFO:0004574) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
GWAS843621_H | GCST90092860 | Free cholesterol levels in large LDL | 115,082 European ancestry individuals | G | 0.778936 | 4E-121 | 120.398 | rs12740374 | 0.114164 | free cholesterol measurement (EFO:0008591) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
None Available | GCST90092847 | Cholesteryl esters to total lipids ratio in large HDL | 115,082 European ancestry individuals | G | 0.778936 | 3E-22 | 21.523 | rs12740374 | 0.0459034 | cholesteryl esters:total lipids ratio (EFO:0020944) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
GWAS848936_H | GCST90399673 | Abdominal aortic aneurysm | 58 African ancestry cases, 6,731 African ancestry controls, 77 Admixed American ancestry cases, 9,335 Admixed American ancestry controls, 1,155 East Asian ancestry cases, 173,601 East Asian ancestry controls, 8,163 European ancestry cases, 1,256,755 European ancestry controls | T | 0.1999 | 1E-18 | 18 | rs12740374 | 0.18422 | Abdominal Aortic Aneurysm (EFO:0004214) |
PMID:36777996 |
None Available | GCST90101741 | Low density lipoprotein cholesterol levels | 10,389 Sub-Saharan African ancestry individuals | G | NR | 3E-15 | 14.523 | rs12740374 | 0.125 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35546142 |
GWAS861259_H | GCST90101745 | Low density lipoprotein cholesterol levels | 24,515 Sub-Saharan African ancestry individuals | G | NR | 1E-39 | 39 | rs12740374 | 0.138022 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35546142 |
GWAS862377_H | GCST90179477 | LDL cholesterol levels | 75,441 East Asian ancestry individuals | ? | NR | 5E-81 | 80.302 | rs12740374 | 0.0222 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:36142332 |
GWAS862533_H | GCST90092889 | Average diameter for LDL particles | 115,082 European ancestry individuals | G | 0.778936 | 4E-28 | 27.398 | rs12740374 | 0.0532475 | low density lipoprotein particle size measurement (EFO:0008593) |
PMID:35213538 |
GWAS864039_H | GCST90092888 | Phospholipid levels in LDL | 115,082 European ancestry individuals | G | 0.778936 | 2E-130 | 129.699 | rs12740374 | 0.120477 | low density lipoprotein cholesterol measurement (EFO:0004611) phospholipid measurement (EFO:0004639) |
PMID:35213538 |
GWAS864299_H | GCST90092886 | Total lipid levels in LDL | 115,082 European ancestry individuals | G | 0.778936 | 3E-125 | 124.523 | rs12740374 | 0.117818 | low density lipoprotein cholesterol measurement (EFO:0004611) lipid measurement (EFO:0004529) |
PMID:35213538 |
GWAS864312_H | GCST90092887 | Concentration of LDL particles | 115,082 European ancestry individuals | G | 0.778936 | 1E-132 | 132 | rs12740374 | 0.121609 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
None Available | GCST90101743 | Total cholesterol levels | 10,486 Sub-Saharan African ancestry individuals | G | NR | 2E-10 | 9.699 | rs12740374 | 0.1 | total cholesterol measurement (EFO:0004574) |
PMID:35546142 |
GWAS865645_H | GCST90101747 | Total cholesterol levels | 24,612 Sub-Saharan African ancestry individuals | G | NR | 3E-25 | 24.523 | rs12740374 | 0.107826 | total cholesterol measurement (EFO:0004574) |
PMID:35546142 |
None Available | GCST90314744 | F7/PROC protein level ratio | 43,509 European ancestry individuals | ? | NR | 3E-38 | 37.523 | rs12740374 | 0.106402 | blood protein measurement (EFO:0007937) |
PMID:38412862 |
GWAS879437_H | GCST004963 | Lipoprotein phospholipase A2 activity in cardiovascular disease | 22,156 European, Asian, African, Arabic, Native American, Pacific Islander and other ancestry | T | 0.17646 | 4E-39 | 38.398 | rs12740374 | 7.44 | lipoprotein-associated phospholipase A(2) measurement (EFO:0004746) |
PMID:28753643 |
None Available | GCST90313953 | CDH3/TNFRSF21 protein level ratio | 43,509 European ancestry individuals | ? | NR | 9E-38 | 37.046 | rs12740374 | 0.100286 | blood protein measurement (EFO:0007937) |
PMID:38412862 |
None Available | GCST90092838 | Concentration of IDL particles | 115,082 European ancestry individuals | G | 0.778936 | 2E-89 | 88.699 | rs12740374 | 0.0985665 | intermediate density lipoprotein measurement (EFO:0008595) |
PMID:35213538 |
None Available | GCST90104005 | Familial combined hyperlipidemia defined by Dutch criteria | 17,485 British ancestry cases, 331,737 British ancestry controls | G | 0.778104 | 4E-72 | 71.398 | rs12740374 | 0.250404 | PMID:34906840 | |
GWAS888084_H | GCST90104006 | Familial combined hyperlipidemia defined by Consensus criteria | 39,961 British ancestry cases, 309,261 British ancestry controls | G | 0.778104 | 7E-175 | 174.155 | rs12740374 | 0.269572 | PMID:34906840 | |
GWAS888442_H | GCST90092810 | Ratio of apolipoprotein B to apolipoprotein A1 levels | 115,082 European ancestry individuals | G | 0.778936 | 7E-124 | 123.155 | rs12740374 | 0.115691 | apolipoprotein A 1 measurement (EFO:0004614) apolipoprotein B measurement (EFO:0004615) |
PMID:35213538 |
GWAS889033_H | GCST90104007 | Familial combined hyperlipidemia defined by Mexico criteria | 5,153 British ancestry cases, 344,069 British ancestry controls | G | 0.778104 | 3E-57 | 56.523 | rs12740374 | 0.408779 | PMID:34906840 | |
GWAS889375_H | GCST90092839 | Phospholipid levels in IDL | 115,082 European ancestry individuals | G | 0.778936 | 4E-99 | 98.398 | rs12740374 | 0.101234 | phospholipid measurement (EFO:0004639) intermediate density lipoprotein measurement (EFO:0008595) |
PMID:35213538 |
None Available | GCST90092837 | Total lipid levels in IDL | 115,082 European ancestry individuals | G | 0.778936 | 3E-90 | 89.523 | rs12740374 | 0.0967477 | lipid measurement (EFO:0004529) intermediate density lipoprotein measurement (EFO:0008595) |
PMID:35213538 |
GWAS893343_H | GCST90092835 | Free cholesterol levels in IDL | 115,082 European ancestry individuals | G | 0.778936 | 8E-96 | 95.097 | rs12740374 | 0.0998514 | free cholesterol measurement (EFO:0008591) intermediate density lipoprotein measurement (EFO:0008595) |
PMID:35213538 |
GWAS894613_H | GCST90104003 | Familial combined hyperlipidemia defined by Brunzell criteria | 3,838 British ancestry cases, 345,384 British ancestry controls | G | 0.778104 | 9E-39 | 38.046 | rs12740374 | 0.384929 | PMID:34906840 | |
GWAS902442_H | GCST90092915 | Triglycerides to total lipids ratio in medium LDL | 115,082 European ancestry individuals | G | 0.778936 | 2E-27 | 26.699 | rs12740374 | 0.0528179 | triglycerides:total lipids ratio (EFO:0020947) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
GWAS902479_H | GCST90092930 | Total cholesterol minus HDL-C levels | 115,082 European ancestry individuals | G | 0.778936 | 2E-107 | 106.699 | rs12740374 | 0.108739 | total cholesterol measurement (EFO:0004574) |
PMID:35213538 |
GWAS903538_H | GCST90092910 | Total lipid levels in medium LDL | 115,082 European ancestry individuals | G | 0.778936 | 2E-116 | 115.699 | rs12740374 | 0.114057 | low density lipoprotein cholesterol measurement (EFO:0004611) lipid measurement (EFO:0004529) |
PMID:35213538 |
GWAS903939_H | GCST90092927 | Triglycerides to total lipids ratio in medium VLDL | 115,082 European ancestry individuals | G | 0.778936 | 8E-48 | 47.097 | rs12740374 | 0.0680218 | triglycerides:total lipids ratio (EFO:0020947) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS904023_H | GCST90092908 | Free cholesterol levels in medium LDL | 115,082 European ancestry individuals | G | 0.778936 | 2E-137 | 136.699 | rs12740374 | 0.123837 | free cholesterol measurement (EFO:0008591) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
GWAS905818_H | GCST90162226 | Granulins levels | 2,935 Qatari ancestry individuals | T | 0.173483 | 4E-104 | 103.398 | rs12740374 | 0.76968 | granulins measurement (EFO:0008141) |
PMID:36168886 |
GWAS906315_H | GCST90092912 | Phospholipid levels in medium LDL | 115,082 European ancestry individuals | G | 0.778936 | 4E-127 | 126.398 | rs12740374 | 0.119299 | low density lipoprotein cholesterol measurement (EFO:0004611) phospholipid measurement (EFO:0004639) |
PMID:35213538 |
None Available | GCST90092909 | Free cholesterol to total lipids ratio in medium LDL | 115,082 European ancestry individuals | G | 0.778936 | 3E-11 | 10.523 | rs12740374 | 0.0314884 | low density lipoprotein cholesterol measurement (EFO:0004611) free cholesterol:total lipids ratio (EFO:0020945) |
PMID:35213538 |
None Available | GCST90092918 | Cholesteryl ester levels in medium VLDL | 115,082 European ancestry individuals | G | 0.778936 | 2E-116 | 115.699 | rs12740374 | 0.112868 | cholesteryl ester measurement (EFO:0010351) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
None Available | GCST90432152 | Abdominal aortic aneurysm | 37,214 European ancestry cases, 997,776 European ancestry controls, 2,007 African ancestry cases, 88,331 African ancestry controls | ? | NR | 2E-42 | 41.699 | rs12740374 | 0.132 | Abdominal Aortic Aneurysm (EFO:0004214) |
PMID:37845353 |
GWAS907333_H | GCST90092904 | Cholesterol levels in medium LDL | 115,082 European ancestry individuals | G | 0.778936 | 5E-114 | 113.302 | rs12740374 | 0.112923 | total cholesterol measurement (EFO:0004574) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
GWAS909511_H | GCST90092906 | Cholesteryl ester levels in medium LDL | 115,082 European ancestry individuals | G | 0.778936 | 9E-101 | 100.046 | rs12740374 | 0.105986 | cholesteryl ester measurement (EFO:0010351) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
GWAS910737_H | GCST90432175 | Myocardial infarction | 3,950 Saudi Arabian ancestry cases, 2,324 Saudi Arabian ancestry controls, 56,278 European and unknown ancestry cases, 577,716 European and unknown ancestry controls | ? | NR | 6E-30 | 29.222 | rs12740374 | 1.1073 | myocardial infarction (EFO:0000612) |
PMID:38072966 |
GWAS915228_H | GCST90092842 | Triglycerides to total lipids ratio in IDL | 115,082 European ancestry individuals | G | 0.778936 | 6E-20 | 19.222 | rs12740374 | 0.0435856 | triglycerides:total lipids ratio (EFO:0020947) intermediate density lipoprotein measurement (EFO:0008595) |
PMID:35213538 |
GWAS915589_H | GCST90092845 | Cholesterol to total lipids ratio in large HDL | 115,082 European ancestry individuals | G | 0.778936 | 3E-31 | 30.523 | rs12740374 | 0.0542092 | cholesterol:total lipids ratio (EFO:0020943) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
GWAS918537_H | GCST90092831 | Cholesterol levels in IDL | 115,082 European ancestry individuals | G | 0.778936 | 3E-85 | 84.523 | rs12740374 | 0.0938861 | total cholesterol measurement (EFO:0004574) intermediate density lipoprotein measurement (EFO:0008595) |
PMID:35213538 |
GWAS918729_H | GCST90092832 | Cholesterol to total lipids ratio in IDL | 115,082 European ancestry individuals | G | 0.778936 | 2E-11 | 10.699 | rs12740374 | 0.0322478 | cholesterol:total lipids ratio (EFO:0020943) intermediate density lipoprotein measurement (EFO:0008595) |
PMID:35213538 |
GWAS918880_H | GCST90092833 | Cholesteryl ester levels in IDL | 115,082 European ancestry individuals | G | 0.778936 | 3E-80 | 79.523 | rs12740374 | 0.0910478 | cholesteryl ester measurement (EFO:0010351) intermediate density lipoprotein measurement (EFO:0008595) |
PMID:35213538 |
None Available | GCST90239654 | High density lipoprotein cholesterol levels | 40,963 South Asian ancestry individuals | T | 0.251518 | 9E-10 | 9.046 | rs12740374 | 0.0513231 | high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:34887591 |
None Available | GCST90092901 | Phospholipids to total lipids ratio in medium HDL | 115,082 European ancestry individuals | G | 0.778936 | 7E-18 | 17.155 | rs12740374 | 0.0406165 | phospholipids:total lipids ratio (EFO:0020946) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
None Available | GCST90092897 | Free cholesterol to total lipids ratio in medium HDL | 115,082 European ancestry individuals | G | 0.778936 | 2E-12 | 11.699 | rs12740374 | 0.0310165 | free cholesterol:total lipids ratio (EFO:0020945) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
GWAS932859_H | GCST90239649 | High density lipoprotein cholesterol levels | 40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals | ? | NR | 1E-97 | 97 | rs12740374 | N/A | high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:34887591 |
GWAS934837_H | GCST90092917 | Cholesterol to total lipids ratio in medium VLDL | 115,082 European ancestry individuals | G | 0.778936 | 4E-42 | 41.398 | rs12740374 | 0.063415 | very low density lipoprotein cholesterol measurement (EFO:0008317) cholesterol:total lipids ratio (EFO:0020943) |
PMID:35213538 |
GWAS935254_H | GCST90092923 | Concentration of medium VLDL particles | 115,082 European ancestry individuals | G | 0.778936 | 2E-72 | 71.699 | rs12740374 | 0.0891177 | very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS936108_H | GCST90092911 | Concentration of medium LDL particles | 115,082 European ancestry individuals | G | 0.778936 | 6E-99 | 98.222 | rs12740374 | 0.105127 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
GWAS936925_H | GCST90092916 | Cholesterol levels in medium VLDL | 115,082 European ancestry individuals | G | 0.778936 | 4E-109 | 108.398 | rs12740374 | 0.10991 | total cholesterol measurement (EFO:0004574) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS937459_H | GCST90092924 | Phospholipid levels in medium VLDL | 115,082 European ancestry individuals | G | 0.778936 | 5E-76 | 75.302 | rs12740374 | 0.0914653 | very low density lipoprotein cholesterol measurement (EFO:0008317) phospholipid measurement (EFO:0004639) |
PMID:35213538 |
GWAS938383_H | GCST90092925 | Phospholipids to total lipids ratio in medium VLDL | 115,082 European ancestry individuals | G | 0.778936 | 4E-64 | 63.398 | rs12740374 | 0.080568 | very low density lipoprotein cholesterol measurement (EFO:0008317) phospholipids:total lipids ratio (EFO:0020946) |
PMID:35213538 |
GWAS938892_H | GCST90092998 | Free cholesterol levels in VLDL | 115,082 European ancestry individuals | G | 0.778936 | 1E-44 | 44 | rs12740374 | 0.0689646 | free cholesterol measurement (EFO:0008591) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS941579_H | GCST90092953 | Phospholipids to total lipids ratio in small HDL | 115,082 European ancestry individuals | G | 0.778936 | 5E-130 | 129.302 | rs12740374 | 0.116224 | phospholipids:total lipids ratio (EFO:0020946) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
GWAS941814_H | GCST90093000 | Concentration of VLDL particles | 115,082 European ancestry individuals | G | 0.778936 | 2E-53 | 52.699 | rs12740374 | 0.0758495 | very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS942327_H | GCST90239656 | Low density lipoprotein cholesterol levels | 99,432 Admixed African or African ancestry individuals | T | 0.254835 | 2E-177 | 176.699 | rs12740374 | 0.155286 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:34887591 |
None Available | GCST90092920 | Free cholesterol levels in medium VLDL | 115,082 European ancestry individuals | G | 0.778936 | 4E-88 | 87.398 | rs12740374 | 0.0987901 | free cholesterol measurement (EFO:0008591) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS945581_H | GCST90092922 | Total lipid levels in medium VLDL | 115,082 European ancestry individuals | G | 0.778936 | 5E-56 | 55.302 | rs12740374 | 0.0777174 | very low density lipoprotein cholesterol measurement (EFO:0008317) lipid measurement (EFO:0004529) |
PMID:35213538 |
GWAS946436_H | GCST90092997 | Cholesteryl ester levels in VLDL | 115,082 European ancestry individuals | G | 0.778936 | 5E-72 | 71.302 | rs12740374 | 0.0891319 | cholesteryl ester measurement (EFO:0010351) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS947177_H | GCST90092919 | Cholesteryl esters to total lipids ratio in medium VLDL | 115,082 European ancestry individuals | G | 0.778936 | 1E-37 | 37 | rs12740374 | 0.0596786 | very low density lipoprotein cholesterol measurement (EFO:0008317) cholesteryl esters:total lipids ratio (EFO:0020944) |
PMID:35213538 |
GWAS947427_H | GCST90092921 | Free cholesterol to total lipids ratio in medium VLDL | 115,082 European ancestry individuals | G | 0.778936 | 9E-54 | 53.046 | rs12740374 | 0.0729239 | very low density lipoprotein cholesterol measurement (EFO:0008317) free cholesterol:total lipids ratio (EFO:0020945) |
PMID:35213538 |
GWAS956750_H | GCST90092883 | LDL cholesterol levels | 115,082 European ancestry individuals | G | 0.778936 | 4E-124 | 123.398 | rs12740374 | 0.117191 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
None Available | GCST90092985 | Total cholesterol levels | 115,082 European ancestry individuals | G | 0.778936 | 4E-83 | 82.398 | rs12740374 | 0.0929169 | total cholesterol measurement (EFO:0004574) |
PMID:35213538 |
GWAS958690_H | GCST90092809 | Apolipoprotein B levels | 115,082 European ancestry individuals | G | 0.778936 | 8E-121 | 120.097 | rs12740374 | 0.115903 | apolipoprotein B measurement (EFO:0004615) |
PMID:35213538 |
GWAS958872_H | GCST90092814 | Clinical LDL cholesterol levels | 115,082 European ancestry individuals | G | 0.778936 | 5E-124 | 123.302 | rs12740374 | 0.117024 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
None Available | GCST90093039 | Triglycerides to total lipids ratio in very small VLDL | 115,082 European ancestry individuals | G | 0.778936 | 1E-25 | 25 | rs12740374 | 0.0491432 | triglycerides:total lipids ratio (EFO:0020947) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS960573_H | GCST90092988 | Total free cholesterol levels | 115,082 European ancestry individuals | G | 0.778936 | 2E-87 | 86.699 | rs12740374 | 0.0961379 | free cholesterol measurement (EFO:0008591) |
PMID:35213538 |
GWAS960958_H | GCST90239655 | Low density lipoprotein cholesterol levels | 40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals | ? | NR | 1E-2031 | 2031 | rs12740374 | N/A | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:34887591 |
GWAS961570_H | GCST90092971 | Cholesteryl esters to total lipids ratio in small VLDL | 115,082 European ancestry individuals | G | 0.778936 | 4E-66 | 65.398 | rs12740374 | 0.0840691 | very low density lipoprotein cholesterol measurement (EFO:0008317) cholesteryl esters:total lipids ratio (EFO:0020944) |
PMID:35213538 |
GWAS962092_H | GCST90093029 | Cholesterol to total lipids ratio in very small VLDL | 115,082 European ancestry individuals | G | 0.778936 | 9E-19 | 18.046 | rs12740374 | 0.0414643 | very low density lipoprotein cholesterol measurement (EFO:0008317) cholesterol:total lipids ratio (EFO:0020943) |
PMID:35213538 |
None Available | GCST90132287 | Ideal cardiovascular health score (clinical and behavioral) | 119,129 European ancestry individuals, 16,495 African American individuals, 6,780 Hispanic individuals | T | 0.22 | 3E-15 | 14.523 | rs12740374 | 0.06 | clinical and behavioural ideal cardiovascular health (EFO:0007654) |
PMID:35613103 |
None Available | GCST90092986 | Total esterified cholesterol levels | 115,082 European ancestry individuals | G | 0.778936 | 3E-80 | 79.523 | rs12740374 | 0.0909029 | esterified cholesterol measurement (EFO:0008589) |
PMID:35213538 |
GWAS963548_H | GCST90092972 | Free cholesterol levels in small VLDL | 115,082 European ancestry individuals | G | 0.778936 | 2E-103 | 102.699 | rs12740374 | 0.107157 | free cholesterol measurement (EFO:0008591) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS964492_H | GCST90092962 | Total lipid levels in small LDL | 115,082 European ancestry individuals | G | 0.778936 | 3E-144 | 143.523 | rs12740374 | 0.126975 | low density lipoprotein cholesterol measurement (EFO:0004611) lipid measurement (EFO:0004529) |
PMID:35213538 |
GWAS964984_H | GCST90092947 | Cholesteryl esters to total lipids ratio in small HDL | 115,082 European ancestry individuals | G | 0.778936 | 5E-21 | 20.302 | rs12740374 | 0.04565 | cholesteryl esters:total lipids ratio (EFO:0020944) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
GWAS965034_H | GCST90092958 | Cholesteryl ester levels in small LDL | 115,082 European ancestry individuals | G | 0.778936 | 1E-113 | 113 | rs12740374 | 0.112602 | cholesteryl ester measurement (EFO:0010351) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
None Available | GCST90093005 | Cholesterol to total lipids ratio in very large HDL | 115,056 European ancestry individuals | G | 0.778942 | 1E-27 | 27 | rs12740374 | 0.051526 | cholesterol:total lipids ratio (EFO:0020943) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
GWAS966450_H | GCST90092970 | Cholesteryl ester levels in small VLDL | 115,082 European ancestry individuals | G | 0.778936 | 3E-82 | 81.523 | rs12740374 | 0.0951484 | cholesteryl ester measurement (EFO:0010351) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS966889_H | GCST90092956 | Cholesterol levels in small LDL | 115,082 European ancestry individuals | G | 0.778936 | 3E-134 | 133.523 | rs12740374 | 0.122581 | total cholesterol measurement (EFO:0004574) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
GWAS966948_H | GCST90092973 | Free cholesterol to total lipids ratio in small VLDL | 115,082 European ancestry individuals | G | 0.778936 | 5E-57 | 56.302 | rs12740374 | 0.0750547 | very low density lipoprotein cholesterol measurement (EFO:0008317) free cholesterol:total lipids ratio (EFO:0020945) |
PMID:35213538 |
None Available | GCST90161722 | Hemojuvelin levels | 2,935 Qatari ancestry individuals | T | 0.173483 | 2E-12 | 11.699 | rs12740374 | 0.247585 | hemojuvelin measurement (EFO:0008148) |
PMID:36168886 |
GWAS968228_H | GCST90239668 | Non-HDL cholesterol levels | 99,432 Admixed African or African ancestry individuals | T | 0.253901 | 2E-52 | 51.699 | rs12740374 | 0.14937 | non-high density lipoprotein cholesterol measurement (EFO:0005689) |
PMID:34887591 |
GWAS968510_H | GCST90239658 | Low density lipoprotein cholesterol levels | 1,320,016 European ancestry individuals | T | 0.21919 | 7E-1290 | 1289.155 | rs12740374 | 0.148228 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:34887591 |
GWAS968990_H | GCST90092949 | Free cholesterol to total lipids ratio in small HDL | 115,082 European ancestry individuals | G | 0.778936 | 3E-121 | 120.523 | rs12740374 | 0.110127 | free cholesterol:total lipids ratio (EFO:0020945) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
GWAS969076_H | GCST90239609 | Total cholesterol levels | 76,578 Taiwanese ancestry individuals | ? | NR | 2E-62 | 61.699 | rs12740374 | 5.71752 | total cholesterol measurement (EFO:0004574) |
PMID:36329257 |
None Available | GCST90092945 | Cholesterol to total lipids ratio in small HDL | 115,082 European ancestry individuals | G | 0.778936 | 2E-50 | 49.699 | rs12740374 | 0.0728653 | cholesterol:total lipids ratio (EFO:0020943) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
GWAS969625_H | GCST90092943 | Remnant cholesterol (non-HDL, non-LDL -cholesterol) | 115,082 European ancestry individuals | G | 0.778936 | 1E-84 | 84 | rs12740374 | 0.0961513 | remnant cholesterol measurement (EFO:0010815) |
PMID:35213538 |
GWAS969650_H | GCST90092976 | Phospholipid levels in small VLDL | 115,082 European ancestry individuals | G | 0.778936 | 2E-82 | 81.699 | rs12740374 | 0.0951286 | very low density lipoprotein cholesterol measurement (EFO:0008317) phospholipid measurement (EFO:0004639) |
PMID:35213538 |
GWAS969660_H | GCST90092977 | Phospholipids to total lipids ratio in small VLDL | 115,082 European ancestry individuals | G | 0.778936 | 4E-61 | 60.398 | rs12740374 | 0.0779713 | very low density lipoprotein cholesterol measurement (EFO:0008317) phospholipids:total lipids ratio (EFO:0020946) |
PMID:35213538 |
GWAS970125_H | GCST90239670 | Non-HDL cholesterol levels | 1,320,016 European ancestry individuals | T | 0.219397 | 7E-764 | 763.155 | rs12740374 | 0.135806 | non-high density lipoprotein cholesterol measurement (EFO:0005689) |
PMID:34887591 |
GWAS970310_H | GCST90239612 | Low density lipoprotein cholesterol levels | 76,650 Taiwanese ancestry individuals | ? | NR | 4E-75 | 74.398 | rs12740374 | 5.69083 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:36329257 |
GWAS971811_H | GCST90018961 | LDL cholesterol | 343,621 European ancestry individuals, 72,866 East Asian ancestry individuals | T | NR | 1E-410 | 410 | rs12740374 | 0.1173 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:34594039 |
None Available | GCST90179148 | Low-density lipoprotein levels (MTAG) | 361,194 European ancestry individuals | T | NR | 3E-17 | 16.523 | rs12740374 | 0.01414 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:36376304 |
None Available | GCST90093028 | Cholesterol levels in very small VLDL | 115,082 European ancestry individuals | G | 0.778936 | 4E-66 | 65.398 | rs12740374 | 0.0826854 | total cholesterol measurement (EFO:0004574) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS974552_H | GCST90239667 | Non-HDL cholesterol levels | 40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals | ? | NR | 4E-1189 | 1188.398 | rs12740374 | N/A | non-high density lipoprotein cholesterol measurement (EFO:0005689) |
PMID:34887591 |
GWAS974639_H | GCST90092968 | Cholesterol levels in small VLDL | 115,082 European ancestry individuals | G | 0.778936 | 6E-91 | 90.222 | rs12740374 | 0.100262 | total cholesterol measurement (EFO:0004574) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
None Available | GCST90092961 | Free cholesterol to total lipids ratio in small LDL | 115,082 European ancestry individuals | G | 0.778936 | 2E-23 | 22.699 | rs12740374 | 0.0477834 | low density lipoprotein cholesterol measurement (EFO:0004611) free cholesterol:total lipids ratio (EFO:0020945) |
PMID:35213538 |
GWAS975914_H | GCST90092964 | Phospholipid levels in small LDL | 115,082 European ancestry individuals | G | 0.778936 | 2E-185 | 184.699 | rs12740374 | 0.143805 | low density lipoprotein cholesterol measurement (EFO:0004611) phospholipid measurement (EFO:0004639) |
PMID:35213538 |
None Available | GCST90092989 | Total lipid levels in lipoprotein particles | 115,082 European ancestry individuals | G | 0.778936 | 1E-48 | 48 | rs12740374 | 0.0715984 | lipid measurement (EFO:0004529) lipoprotein measurement (EFO:0004732) |
PMID:35213538 |
GWAS976959_H | GCST90092967 | Triglycerides to total lipids ratio in small LDL | 115,082 European ancestry individuals | G | 0.778936 | 1E-32 | 32 | rs12740374 | 0.0569046 | triglycerides:total lipids ratio (EFO:0020947) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
GWAS976993_H | GCST90092963 | Concentration of small LDL particles | 115,082 European ancestry individuals | G | 0.778936 | 3E-114 | 113.523 | rs12740374 | 0.112864 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
GWAS977206_H | GCST90092969 | Cholesterol to total lipids ratio in small VLDL | 115,082 European ancestry individuals | G | 0.778936 | 2E-70 | 69.699 | rs12740374 | 0.0855402 | very low density lipoprotein cholesterol measurement (EFO:0008317) cholesterol:total lipids ratio (EFO:0020943) |
PMID:35213538 |
GWAS977367_H | GCST90092960 | Free cholesterol levels in small LDL | 115,082 European ancestry individuals | G | 0.778936 | 4E-165 | 164.398 | rs12740374 | 0.135763 | free cholesterol measurement (EFO:0008591) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
GWAS978026_H | GCST90239673 | Total cholesterol levels | 40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals | ? | NR | 2E-1497 | 1496.699 | rs12740374 | N/A | total cholesterol measurement (EFO:0004574) |
PMID:34887591 |
GWAS978559_H | GCST90092982 | Sphingomyelin levels | 115,006 European ancestry individuals | G | 0.778916 | 4E-62 | 61.398 | rs12740374 | 0.0772128 | sphingomyelin measurement (EFO:0010118) |
PMID:35213538 |
GWAS979515_H | GCST90092979 | Triglycerides to total lipids ratio in small VLDL | 115,082 European ancestry individuals | G | 0.778936 | 1E-69 | 69 | rs12740374 | 0.0844752 | triglycerides:total lipids ratio (EFO:0020947) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS980049_H | GCST90092996 | VLDL cholesterol levels | 115,082 European ancestry individuals | G | 0.778936 | 7E-61 | 60.155 | rs12740374 | 0.0815422 | very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS980353_H | GCST90093030 | Cholesteryl ester levels in very small VLDL | 115,082 European ancestry individuals | G | 0.778936 | 5E-63 | 62.302 | rs12740374 | 0.0802439 | cholesteryl ester measurement (EFO:0010351) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS980958_H | GCST90093033 | Free cholesterol to total lipids ratio in very small VLDL | 115,082 European ancestry individuals | G | 0.778936 | 2E-68 | 67.699 | rs12740374 | 0.0861586 | very low density lipoprotein cholesterol measurement (EFO:0008317) free cholesterol:total lipids ratio (EFO:0020945) |
PMID:35213538 |
GWAS981653_H | GCST90239676 | Total cholesterol levels | 1,320,016 European ancestry individuals | T | 0.219159 | 2E-903 | 902.699 | rs12740374 | 0.123837 | total cholesterol measurement (EFO:0004574) |
PMID:34887591 |
GWAS981815_H | GCST90093031 | Cholesteryl esters to total lipids ratio in very small VLDL | 115,082 European ancestry individuals | G | 0.778936 | 5E-13 | 12.302 | rs12740374 | 0.0336636 | very low density lipoprotein cholesterol measurement (EFO:0008317) cholesteryl esters:total lipids ratio (EFO:0020944) |
PMID:35213538 |
GWAS982306_H | GCST90093036 | Phospholipid levels in very small VLDL | 115,082 European ancestry individuals | G | 0.778936 | 2E-55 | 54.699 | rs12740374 | 0.0764455 | very low density lipoprotein cholesterol measurement (EFO:0008317) phospholipid measurement (EFO:0004639) |
PMID:35213538 |
None Available | GCST90093032 | Free cholesterol levels in very small VLDL | 115,082 European ancestry individuals | G | 0.778936 | 1E-68 | 68 | rs12740374 | 0.0851144 | free cholesterol measurement (EFO:0008591) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS982631_H | GCST90093035 | Concentration of very small VLDL particles | 115,082 European ancestry individuals | G | 0.778936 | 7E-66 | 65.155 | rs12740374 | 0.0836641 | very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS983060_H | GCST90093034 | Total lipid levels in very small VLDL | 115,082 European ancestry individuals | G | 0.778936 | 4E-55 | 54.398 | rs12740374 | 0.076007 | very low density lipoprotein cholesterol measurement (EFO:0008317) lipid measurement (EFO:0004529) |
PMID:35213538 |
GWAS984912_H | GCST90018974 | Total cholesterol levels | 344,278 European ancestry individuals, 135,808 East Asian ancestry individuals | T | NR | 1E-286 | 286 | rs12740374 | 0.0934 | total cholesterol measurement (EFO:0004574) |
PMID:34594039 |
None Available | GCST90093010 | Total lipid levels in very large HDL | 115,082 European ancestry individuals | G | 0.778936 | 2E-14 | 13.699 | rs12740374 | 0.0341041 | lipid measurement (EFO:0004529) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
None Available | GCST90093004 | Cholesterol levels in very large HDL | 115,082 European ancestry individuals | G | 0.778936 | 2E-26 | 25.699 | rs12740374 | 0.0477394 | total cholesterol measurement (EFO:0004574) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
GWAS993774_H | GCST90093007 | Cholesteryl esters to total lipids ratio in very large HDL | 115,056 European ancestry individuals | G | 0.778942 | 2E-37 | 36.699 | rs12740374 | 0.0632955 | cholesteryl esters:total lipids ratio (EFO:0020944) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
GWAS994305_H | GCST90093008 | Free cholesterol levels in very large HDL | 115,082 European ancestry individuals | G | 0.778936 | 4E-35 | 34.398 | rs12740374 | 0.0572091 | free cholesterol measurement (EFO:0008591) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
GWAS995273_H | GCST90239674 | Total cholesterol levels | 99,432 Admixed African or African ancestry individuals | T | 0.254652 | 6E-137 | 136.222 | rs12740374 | 0.133136 | total cholesterol measurement (EFO:0004574) |
PMID:34887591 |
None Available | GCST90093006 | Cholesteryl ester levels in very large HDL | 115,082 European ancestry individuals | G | 0.778936 | 2E-23 | 22.699 | rs12740374 | 0.0442997 | cholesteryl ester measurement (EFO:0010351) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
GWAS996574_H | GCST90093011 | Concentration of very large HDL particles | 115,082 European ancestry individuals | G | 0.778936 | 1E-26 | 26 | rs12740374 | 0.0477359 | high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
GWAS1011103_H | GCST90018989 | Medication use (HMG CoA reductase inhibitors) | 73,475 European ancestry cases, 216,910 European ancestry controls, 33,295 East Asian ancestry cases, 145,431 East Asian ancestry controls | T | NR | 2E-145 | 144.699 | rs12740374 | 0.1623 | HMG CoA reductase inhibitor use measurement (EFO:0009932) |
PMID:34594039 |
GWAS1013165_H | GCST90018995 | Medication use (salicylic acid and derivatives) | 61,583 European ancestry cases, 50,427 European ancestry controls, 41,461 East Asian ancestry cases, 137,265 East Asian ancestry controls | T | NR | 1E-17 | 17 | rs12740374 | 0.0707 | aspirin use measurement (EFO:0007013) |
PMID:34594039 |
None Available | GCST008370 | Ischemic heart disease (PheCode 411) | 31,355 British ancestry cases, 377,103 British ancestry controls | T | 0.222 | 2E-25 | 24.699 | rs12740374 | N/A | coronary artery disease (EFO:0001645) |
PMID:30104761 |
None Available | GCST90292529 | Total cholesterol levels (MTAG) | 125,000 African ancestry individuals (MTAG boosted by high-density lipoprotein and triglyceride samples) | T | NR | 5E-72 | 71.302 | rs12740374 | 0.072 | total cholesterol measurement (EFO:0004574) |
PMID:37669986 |
GWAS1061044_H | GCST90292528 | Triglyceride levels (MTAG) | 125,000 African ancestry individuals (MTAG boosted by total cholesterol and high-density lipoprotein samples) | T | NR | 6E-24 | 23.222 | rs12740374 | 0.0292 | triglyceride measurement (EFO:0004530) |
PMID:37669986 |
None Available | GCST90446534 | Coronary heart disease | 38,687 European ancestry cases, 420,451 European ancestry controls | ? | NR | 2E-26 | 25.699 | rs12740374 | N/A | coronary artery disease (EFO:0001645) |
PMID:37947095 |
None Available | GCST90446532 | Myocardial infarction | 16,602 European ancestry cases, 442,536 European ancestry controls | ? | NR | 8E-15 | 14.097 | rs12740374 | N/A | myocardial infarction (EFO:0000612) |
PMID:37947095 |
None Available | GCST90435412 | Height | 404,900 European ancestry individuals | ? | NR | 1E-10 | 10 | rs12740374 | 0.0135463 | body height (EFO:0004339) |
PMID:39134668 |
None Available | GCST90448622 | Non-HDL cholesterol levels | 38,000 South Asian ancestry individuals | T | NR | 2E-56 | 55.699 | rs12740374 | 0.167 | non-high density lipoprotein cholesterol measurement (EFO:0005689) |
PMID:39414775 |
None Available | GCST90448631 | Total cholesterol levels | 38,000 South Asian ancestry individuals | T | NR | 2E-119 | 118.699 | rs12740374 | 0.194 | total cholesterol measurement (EFO:0004574) |
PMID:39414775 |
None Available | GCST90448616 | LDL cholesterol levels | 38,000 South Asian ancestry individuals | T | NR | 2E-137 | 136.699 | rs12740374 | 0.221 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:39414775 |
RGD Curation Notes
Note Type | Note | Reference |
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