GWAS684790_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS684790_H (esterified cholesterol measurement QTL GWAS684790 (human)) Homo sapiens

Symbol: GWAS684790_H
Name: esterified cholesterol measurement QTL GWAS684790 (human)
RGD ID: 407035814
Trait: esterified cholesterol measurement
LOD Score: Not Available
P Value: 7.0E-17
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38819,997,495 - 19,997,496RGD_MAPPER_PIPELINEGRCh38
GRCh37819,855,006 - 19,855,007RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS684790_HHumanesterified cholesterol measurement  IAGPrs17411113405850206 GWAS_CATALOGPMID:36764567
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Position Markers

Peak: (rs17411113)
Human AssemblyChrPosition (strand)Source
GRCh38819,997,495 - 19,997,496RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407036162GWAS685138_Hfree cholesterol in small LDL measurement QTL GWAS685138 (human)3e-12free cholesterol in small LDL measurement 81999749519997496Human
1298482BP2_HBlood pressure QTL 2 (human)1.8Blood pressurediastolic8695325632953256Human
407035814GWAS684790_Hesterified cholesterol measurement QTL GWAS684790 (human)7e-17esterified cholesterol measurement81999749519997496Human
407033476GWAS682452_Hfree cholesterol in LDL measurement QTL GWAS682452 (human)2e-16free cholesterol in LDL measurement 81999749519997496Human
407189453GWAS838429_Hfree cholesterol measurement, low density lipoprotein cholesterol measurement QTL GWAS838429 (human)6e-19free cholesterol measurement, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)81999749519997496Human
407289293GWAS938269_Hfree cholesterol measurement, low density lipoprotein cholesterol measurement QTL GWAS938269 (human)6e-09free cholesterol measurement, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)81999749519997496Human
407088686GWAS737662_Hcholesteryl ester measurement QTL GWAS737662 (human)6e-30blood lipid amount (VT:0003949)81999749519997496Human
407091598GWAS740574_Hcholesteryl esters to total lipids in very large HDL percentage QTL GWAS740574 (human)2e-68cholesteryl esters to total lipids in very large HDL percentage 81999749519997496Human
407164170GWAS813146_Hdiacylglycerol 34:2 measurement QTL GWAS813146 (human)8e-22milk diacylglycerol amount (VT:0010385)81999749519997496Human
407211221GWAS860197_Hlipoprotein A measurement QTL GWAS860197 (human)5e-19lipoprotein A measurement81999749519997496Human
407117778GWAS766754_Hfree cholesterol in IDL measurement QTL GWAS766754 (human)5e-27free cholesterol in IDL measurementblood intermediate density lipoprotein cholesterol level (CMO:0001562)81999749519997496Human
1558703SCL6_HSerum cholesterol level QTL 1 (human)1.2Lipid levelHDL cholesterol81246863538468635Human
407327517GWAS976493_Hfree cholesterol measurement, low density lipoprotein cholesterol measurement QTL GWAS976493 (human)9e-15free cholesterol measurement, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)81999749519997496Human
407038841GWAS687817_Hfree cholesterol in large LDL measurement QTL GWAS687817 (human)4e-21free cholesterol in large LDL measurement81999749519997496Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS682452_H GCST90269518 Free cholesterol in LDL (UKB data field 23421) 88,329 European ancestry individuals G 0.100217 2E-16 15.699 rs17411113 0.0640564 free cholesterol in LDL measurement (EFO:0022266)
 PMID:36764567
GWAS684790_H GCST90269512 Total esterified cholesterol levels (UKB data field 23415) 88,329 European ancestry individuals G 0.100217 7E-17 16.155 rs17411113 0.0635165 esterified cholesterol measurement (EFO:0008589)
 PMID:36764567
GWAS685138_H GCST90269646 Free cholesterol in small LDL (UKB data field 23549) 88,329 European ancestry individuals G 0.100217 3E-12 11.523 rs17411113 0.0548811 free cholesterol in small LDL measurement (EFO:0022271)
 PMID:36764567
GWAS687817_H GCST90269632 Free cholesterol in large LDL (UKB data field 23535) 88,329 European ancestry individuals G 0.100217 4E-21 20.398 rs17411113 0.0732148 free cholesterol in large LDL measurement (EFO:0022176)
 PMID:36764567
GWAS737662_H GCST90269673 Cholesteryl esters in small HDL (UKB data field 23576) 88,329 European ancestry individuals G 0.100217 6E-30 29.222 rs17411113 0.0894184 cholesteryl ester measurement (EFO:0010351)
 PMID:36764567
GWAS740574_H GCST90269728 Cholesteryl esters to total lipids in very large HDL percentage (UKB data field 23631) 88,307 European ancestry individuals G 0.100213 2E-68 67.699 rs17411113 0.13654 cholesteryl esters to total lipids in very large HDL percentage (EFO:0022257)
 PMID:36764567
GWAS766754_H GCST90269625 Free cholesterol in IDL (UKB data field 23528) 88,329 European ancestry individuals G 0.100217 5E-27 26.302 rs17411113 0.0822981 free cholesterol in IDL measurement (EFO:0022181)
 PMID:36764567
GWAS813146_H GCST90060606 Diacylglycerol(34:2)_[M+H-H2O]1+ levels 5,662 Pakistani ancestry individuals A NR 8E-22 21.097 rs17411113 0.0913 diacylglycerol 34:2 measurement (EFO:0010353)
 PMID:34503513
GWAS838429_H GCST90092885 Free cholesterol levels in LDL 115,082 European ancestry individuals C 0.90012 6E-19 18.222 rs17411113 0.0604958 free cholesterol measurement (EFO:0008591)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
None Available GCST90060827 Sphingomyelin(42:4)_[M+H]1+ levels 5,662 Pakistani ancestry individuals T NR 8E-22 21.097 rs17411113 0.0975 sphingomyelin measurement (EFO:0010118)
 PMID:34503513
GWAS860197_H GCST012232 Lipoprotein (a) levels 348,591 European ancestry individuals, 6,000 African ancestry individuals, 9,116 Asian ancestry individuals, 7,505 individuals C NR 5E-19 18.302 rs17411113 0.02273 lipoprotein A measurement (EFO:0006925)
 PMID:33730874
None Available GCST90060830 Sphingomyelin(42:3)_[M+H]1+ levels 5,662 Pakistani ancestry individuals T NR 8E-22 21.097 rs17411113 0.0485 sphingomyelin measurement (EFO:0010118)
 PMID:34503513
GWAS938269_H GCST90092908 Free cholesterol levels in medium LDL 115,082 European ancestry individuals C 0.90012 6E-9 8.222 rs17411113 0.0399911 free cholesterol measurement (EFO:0008591)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
GWAS976493_H GCST90092960 Free cholesterol levels in small LDL 115,082 European ancestry individuals C 0.90012 9E-15 14.046 rs17411113 0.0531641 free cholesterol measurement (EFO:0008591)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
None Available GCST90454454 Metabolic syndrome 24,171 Taiwanese ancestry cases, 83,059 Taiwanese ancestry controls C 0.08851 1E-28 28 rs17411113 0.20163 metabolic syndrome (EFO:0000195)
 PMID:38201907
Database Acc Id Source(s)
GWAS Catalog GCST90269512 GWAS Catalog

RGD Curation Notes
Note Type Note Reference