GWAS681156_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS681156_H (cholesteryl ester measurement QTL GWAS681156 (human)) Homo sapiens

Symbol: GWAS681156_H
Name: cholesteryl ester measurement QTL GWAS681156 (human)
RGD ID: 407032180
Trait: blood lipid amount   (VT:0003949)    
LOD Score: Not Available
P Value: 9.0E-19
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3810112,174,626 - 112,174,627RGD_MAPPER_PIPELINEGRCh38
GRCh3710113,934,384 - 113,934,385RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Vertebrate Trait
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS681156_HHumanblood lipid amount  IAGPrs2803619405850206Based on the EFO term IDGWAS_CATALOGPMID:36764567

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS681156_HHumancholesteryl ester measurement  IAGPrs2803619405850206 GWAS_CATALOGPMID:36764567
Experimental Data Annotations     Click to see Annotation Detail View

Vertebrate Trait

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1345985GPAMglycerol-3-phosphate acyltransferase, mitochondrial10112149865112227677Human

Position Markers

Peak: (rs2803619)
Human AssemblyChrPosition (strand)Source
GRCh3810112,174,626 - 112,174,627RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407316870GWAS965846_Htriglycerides:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS965846 (human)3e-09triglycerides:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)10112174626112174627Human
407035655GWAS684631_Hmonounsaturated fatty acids; 16:1, 18:1 measurement QTL GWAS684631 (human)3e-10monounsaturated fatty acids; 16:1, 18:1 measurement10112174626112174627Human
407255438GWAS904414_Htriglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement QTL GWAS904414 (human)1e-08triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)10112174626112174627Human
407320525GWAS969501_Hvery low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio QTL GWAS969501 (human)6e-10very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratioblood very low density lipoprotein cholesterol level (CMO:0000648)10112174626112174627Human
407247115GWAS896091_Hcholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement QTL GWAS896091 (human)4e-26cholesteryl esters:total lipids ratio, intermediate density lipoprotein measurementblood intermediate density lipoprotein cholesterol level (CMO:0001562)10112174626112174627Human
407269000GWAS917976_Hcholesterol:total lipids ratio, intermediate density lipoprotein measurement QTL GWAS917976 (human)1e-24cholesterol:total lipids ratio, intermediate density lipoprotein measurementblood intermediate density lipoprotein cholesterol level (CMO:0001562)10112174626112174627Human
407332937GWAS981913_Hvery low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio QTL GWAS981913 (human)2e-25very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratioblood very low density lipoprotein cholesterol level (CMO:0000648)10112174626112174627Human
407310484GWAS959460_Htriglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement QTL GWAS959460 (human)6e-19triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)10112174626112174627Human
407256853GWAS905829_Hfatty acid measurement QTL GWAS905829 (human)9e-10fatty acid measurement10112174626112174627Human
407318867GWAS967843_Htriglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement QTL GWAS967843 (human)3e-08triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)10112174626112174627Human
407314845GWAS963821_Hvery low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio QTL GWAS963821 (human)2e-11very low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratioblood very low density lipoprotein cholesterol level (CMO:0000648)10112174626112174627Human
407329629GWAS978605_Htriglyceride measurement, phospholipid measurement QTL GWAS978605 (human)4e-11triglyceride measurement, phospholipid measurementblood triglyceride level (CMO:0000118)10112174626112174627Human
407258331GWAS907307_Hvery low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio QTL GWAS907307 (human)2e-08very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratioblood very low density lipoprotein cholesterol level (CMO:0000648)10112174626112174627Human
407098332GWAS747308_Hcholesteryl ester measurement QTL GWAS747308 (human)6e-17blood lipid amount (VT:0003949)10112174626112174627Human
407023840GWAS672816_Hcholesteryl ester measurement QTL GWAS672816 (human)4e-16blood lipid amount (VT:0003949)10112174626112174627Human
407309218GWAS958194_Htriglyceride measurement QTL GWAS958194 (human)2e-29triglyceride measurementblood triglyceride level (CMO:0000118)10112174626112174627Human
407098853GWAS747829_Hcholesterol in large HDL measurement QTL GWAS747829 (human)1e-17triglycerides:total lipids ratio, intermediate density lipoprotein measurementblood intermediate density lipoprotein cholesterol level (CMO:0001562)10112174626112174627Human
407041317GWAS690293_Htriglycerides to phosphoglycerides ratio QTL GWAS690293 (human)5e-10triglycerides to phosphoglycerides ratio 10112174626112174627Human
407182190GWAS831166_Htriglycerides:total lipids ratio, low density lipoprotein cholesterol measurement QTL GWAS831166 (human)8e-09triglycerides:total lipids ratio, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)10112174626112174627Human
407346664GWAS995640_Htotal cholesterol measurement QTL GWAS995640 (human)9e-79total cholesterol measurementblood total cholesterol level (CMO:0000051)10112174626112174627Human
407322484GWAS971460_Hvery low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio QTL GWAS971460 (human)4e-23very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratioblood very low density lipoprotein cholesterol level (CMO:0000648)10112174626112174627Human
407339890GWAS988866_Htriglyceride measurement QTL GWAS988866 (human)2e-21triglyceride measurementblood triglyceride level (CMO:0000118)10112174626112174627Human
407032180GWAS681156_Hcholesteryl ester measurement QTL GWAS681156 (human)9e-19blood lipid amount (VT:0003949)10112174626112174627Human
407093115GWAS742091_Hphospholipids:total lipids ratio QTL GWAS742091 (human)6e-18phospholipids:total lipids ratio10112174626112174627Human
407285183GWAS934159_Hhigh density lipoprotein cholesterol measurement QTL GWAS934159 (human)3e-102high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)10112174626112174627Human
407090431GWAS739407_Hcholesterol in medium HDL measurement QTL GWAS739407 (human)7e-17cholesterol in medium HDL measurement 10112174626112174627Human
407030653GWAS679629_Hhigh density lipoprotein cholesterol measurement QTL GWAS679629 (human)1e-19low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratioblood low density lipoprotein cholesterol level (CMO:0000053)10112174626112174627Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS672816_H GCST90269666 Cholesteryl esters in medium HDL (UKB data field 23569) 88,329 European ancestry individuals G 0.274809 4E-16 15.398 rs2803619 0.0401536 cholesteryl ester measurement (EFO:0010351)
 PMID:36764567
GWAS679629_H GCST90269503 HDL cholesterol levels (UKB data field 23406) 88,329 European ancestry individuals G 0.274809 1E-19 19 rs2803619 0.0435474 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:36764567
GWAS681156_H GCST90269515 Cholesteryl esters in HDL (UKB data field 23418) 88,329 European ancestry individuals G 0.274809 9E-19 18.046 rs2803619 0.0426431 cholesteryl ester measurement (EFO:0010351)
 PMID:36764567
GWAS684631_H GCST90269551 Monounsaturated fatty acids to total fatty acids percentage (UKB data field 23454) 88,268 European ancestry individuals G 0.274761 3E-10 9.523 rs2803619 0.032238 monounsaturated fatty acids (EFO:0022187)
 PMID:36764567
GWAS690293_H GCST90269532 Triglycerides to phosphoglycerides ratio (UKB data field 23435) 88,268 European ancestry individuals G 0.274761 5E-10 9.302 rs2803619 0.0309403 triglycerides to phosphoglycerides ratio (EFO:0022327)
 PMID:36764567
GWAS739407_H GCST90269665 Cholesterol in medium HDL (UKB data field 23568) 88,329 European ancestry individuals G 0.274809 7E-17 16.155 rs2803619 0.0409669 cholesterol in medium HDL measurement (EFO:0021903)
 PMID:36764567
GWAS742091_H GCST90269706 Phospholipids to total lipids in IDL percentage (UKB data field 23609) 88,329 European ancestry individuals G 0.274809 6E-18 17.222 rs2803619 0.0458126 phospholipids:total lipids ratio (EFO:0020946)
 PMID:36764567
GWAS747308_H GCST90269659 Cholesteryl esters in large HDL (UKB data field 23562) 88,329 European ancestry individuals G 0.274809 6E-17 16.222 rs2803619 0.039855 cholesteryl ester measurement (EFO:0010351)
 PMID:36764567
GWAS747829_H GCST90269658 Cholesterol in large HDL (UKB data field 23561) 88,329 European ancestry individuals G 0.274809 1E-17 17 rs2803619 0.0406038 cholesterol in large HDL measurement (EFO:0021900)
 PMID:36764567
None Available GCST90269657 Phospholipids in large HDL (UKB data field 23560) 88,329 European ancestry individuals G 0.274809 1E-19 19 rs2803619 0.0429904 phospholipids in large HDL measurement (EFO:0022190)
 PMID:36764567
GWAS831166_H GCST90092867 Triglycerides to total lipids ratio in large LDL 115,082 European ancestry individuals G 0.275645 8E-9 8.097 rs2803619 0.0258923 triglycerides:total lipids ratio (EFO:0020947)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
None Available GCST90092861 Free cholesterol to total lipids ratio in large LDL 115,082 European ancestry individuals G 0.275645 1E-19 19 rs2803619 0.039834 low density lipoprotein cholesterol measurement (EFO:0004611)
free cholesterol:total lipids ratio (EFO:0020945)
 PMID:35213538
GWAS896091_H GCST90092834 Cholesteryl esters to total lipids ratio in IDL 115,082 European ancestry individuals G 0.275645 4E-26 25.398 rs2803619 0.0475019 cholesteryl esters:total lipids ratio (EFO:0020944)
intermediate density lipoprotein measurement (EFO:0008595)
 PMID:35213538
GWAS904414_H GCST90092927 Triglycerides to total lipids ratio in medium VLDL 115,082 European ancestry individuals G 0.275645 1E-8 8 rs2803619 0.0248955 triglycerides:total lipids ratio (EFO:0020947)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
GWAS905829_H GCST90092929 Ratio of monounsaturated fatty acids to total fatty acids 115,006 European ancestry individuals G 0.275615 9E-10 9.046 rs2803619 0.0270958 fatty acid measurement (EFO:0005110)
 PMID:35213538
GWAS907307_H GCST90092917 Cholesterol to total lipids ratio in medium VLDL 115,082 European ancestry individuals G 0.275645 2E-8 7.699 rs2803619 0.0244427 very low density lipoprotein cholesterol measurement (EFO:0008317)
cholesterol:total lipids ratio (EFO:0020943)
 PMID:35213538
None Available GCST90092842 Triglycerides to total lipids ratio in IDL 115,082 European ancestry individuals G 0.275645 1E-17 17 rs2803619 0.0378531 triglycerides:total lipids ratio (EFO:0020947)
intermediate density lipoprotein measurement (EFO:0008595)
 PMID:35213538
GWAS917976_H GCST90092832 Cholesterol to total lipids ratio in IDL 115,082 European ancestry individuals G 0.275645 1E-24 24 rs2803619 0.0460544 cholesterol:total lipids ratio (EFO:0020943)
intermediate density lipoprotein measurement (EFO:0008595)
 PMID:35213538
GWAS934159_H GCST90239649 High density lipoprotein cholesterol levels 40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals ? NR 3E-102 101.523 rs2803619 N/A high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:34887591
GWAS958194_H GCST90239661 Triglyceride levels 40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals ? NR 2E-29 28.699 rs2803619 N/A triglyceride measurement (EFO:0004530)
 PMID:34887591
GWAS959460_H GCST90093039 Triglycerides to total lipids ratio in very small VLDL 115,082 European ancestry individuals G 0.275645 6E-19 18.222 rs2803619 0.0388311 triglycerides:total lipids ratio (EFO:0020947)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
GWAS963821_H GCST90092973 Free cholesterol to total lipids ratio in small VLDL 115,082 European ancestry individuals G 0.275645 2E-11 10.699 rs2803619 0.0296363 very low density lipoprotein cholesterol measurement (EFO:0008317)
free cholesterol:total lipids ratio (EFO:0020945)
 PMID:35213538
GWAS965846_H GCST90092955 Triglycerides to total lipids ratio in small HDL 115,082 European ancestry individuals G 0.275645 3E-9 8.523 rs2803619 0.0260671 triglycerides:total lipids ratio (EFO:0020947)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS967843_H GCST90092979 Triglycerides to total lipids ratio in small VLDL 115,082 European ancestry individuals G 0.275645 3E-8 7.523 rs2803619 0.0248417 triglycerides:total lipids ratio (EFO:0020947)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
GWAS969501_H GCST90092977 Phospholipids to total lipids ratio in small VLDL 115,082 European ancestry individuals G 0.275645 6E-10 9.222 rs2803619 0.027193 very low density lipoprotein cholesterol measurement (EFO:0008317)
phospholipids:total lipids ratio (EFO:0020946)
 PMID:35213538
GWAS971460_H GCST90093029 Cholesterol to total lipids ratio in very small VLDL 115,082 European ancestry individuals G 0.275645 4E-23 22.398 rs2803619 0.0432336 very low density lipoprotein cholesterol measurement (EFO:0008317)
cholesterol:total lipids ratio (EFO:0020943)
 PMID:35213538
GWAS978605_H GCST90092983 Ratio of triglycerides to phosphoglycerides 115,006 European ancestry individuals G 0.275615 4E-11 10.398 rs2803619 0.0282601 triglyceride measurement (EFO:0004530)
phospholipid measurement (EFO:0004639)
 PMID:35213538
GWAS981913_H GCST90093031 Cholesteryl esters to total lipids ratio in very small VLDL 115,082 European ancestry individuals G 0.275645 2E-25 24.699 rs2803619 0.0450586 very low density lipoprotein cholesterol measurement (EFO:0008317)
cholesteryl esters:total lipids ratio (EFO:0020944)
 PMID:35213538
GWAS988866_H GCST90239664 Triglyceride levels 1,320,016 European ancestry individuals C 0.718438 2E-21 20.699 rs2803619 0.0179132 triglyceride measurement (EFO:0004530)
 PMID:34887591
GWAS995640_H GCST90239673 Total cholesterol levels 40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals ? NR 9E-79 78.046 rs2803619 N/A total cholesterol measurement (EFO:0004574)
 PMID:34887591
Database Acc Id Source(s)
GWAS Catalog GCST90269515 GWAS Catalog

RGD Curation Notes
Note Type Note Reference