GWAS680229_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS680229_H (intermediate density lipoprotein measurement QTL GWAS680229 (human)) Homo sapiens

Symbol: GWAS680229_H
Name: intermediate density lipoprotein measurement QTL GWAS680229 (human)
RGD ID: 407031253
Trait: intermediate density lipoprotein measurement
Measurement Type: blood intermediate density lipoprotein cholesterol level   (CMO:0001562)    
LOD Score: Not Available
P Value: 4.0E-26
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381944,898,611 - 44,898,612RGD_MAPPER_PIPELINEGRCh38
GRCh371945,401,868 - 45,401,869RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS680229_HHumanblood intermediate density lipoprotein cholesterol level  IAGPrs118170342405850206Based on the EFO term IDGWAS_CATALOGPMID:36764567

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS680229_HHumanintermediate density lipoprotein measurement  IAGPrs118170342405850206 GWAS_CATALOGPMID:36764567
Experimental Data Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1343121TOMM40translocase of outer mitochondrial membrane 40194489125444903689Human

Position Markers

Peak: (rs118170342)
Human AssemblyChrPosition (strand)Source
GRCh381944,898,611 - 44,898,612RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407078978GWAS727954_Htriglycerides to total lipids in small VLDL percentage QTL GWAS727954 (human)1e-13triglycerides to total lipids in small VLDL percentage 194489861144898612Human
407118727GWAS767703_Hcholesterol in IDL measurement QTL GWAS767703 (human)9e-23cholesterol in IDL measurement 194489861144898612Human
407040710GWAS689686_Hfree cholesterol in LDL measurement QTL GWAS689686 (human)8e-26free cholesterol in LDL measurement 194489861144898612Human
407030087GWAS679063_Hcholesterol in very small VLDL measurement QTL GWAS679063 (human)2e-18cholesterol in very small VLDL measurement 194489861144898612Human
407029447GWAS678423_Hlow density lipoprotein cholesterol measurement QTL GWAS678423 (human)5e-26low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)194489861144898612Human
407025483GWAS674459_Hcholesterol to total lipids in large LDL percentage QTL GWAS674459 (human)4e-12cholesterol to total lipids in large LDL percentage 194489861144898612Human
407039819GWAS688795_Hfree cholesterol in large LDL measurement QTL GWAS688795 (human)4e-24free cholesterol in large LDL measurement194489861144898612Human
407298184GWAS947160_Hcholesteryl ester measurement, very low density lipoprotein cholesterol measurement QTL GWAS947160 (human)2e-33blood lipid amount (VT:0003949)blood very low density lipoprotein cholesterol level (CMO:0000648)194489861144898612Human
407037522GWAS686498_Htotal lipids in small LDL QTL GWAS686498 (human)7e-33total lipids in small LDL194489861144898612Human
1559110SCL22_HSerum cholesterol level QTL 22 (human)3.590.000241Lipid levelLDL cholesterol193190759457907594Human
407036755GWAS685731_Hcholesterol in small LDL measurement QTL GWAS685731 (human)4e-30cholesterol in small LDL measurement 194489861144898612Human
407079574GWAS728550_Hfree cholesterol to total lipids in small VLDL percentage QTL GWAS728550 (human)1e-10free cholesterol to total lipids in small VLDL percentage 194489861144898612Human
407031253GWAS680229_Hintermediate density lipoprotein measurement QTL GWAS680229 (human)4e-26intermediate density lipoprotein measurementblood intermediate density lipoprotein cholesterol level (CMO:0001562)194489861144898612Human
407035733GWAS684709_Hfree cholesterol in medium LDL measurement QTL GWAS684709 (human)7e-26blood lipid amount (VT:0003949)194489861144898612Human
407037275GWAS686251_Hphospholipids in LDL measurement QTL GWAS686251 (human)6e-28phospholipids in LDL measurement 194489861144898612Human
407038617GWAS687593_Htotal lipids in LDL measurement QTL GWAS687593 (human)2e-26total lipids in LDL measurement 194489861144898612Human
407038745GWAS687721_Htotal lipids in large LDL QTL GWAS687721 (human)2e-25total lipids in large LDL194489861144898612Human
1331657COPD9_HChronic obstructive pulmonary disease QTL 9 (human)1.94Chronic airflow obstructionpost-bronchodilator FEV1193102176057021760Human
407039068GWAS688044_Hphospholipids in medium LDL measurement QTL GWAS688044 (human)1e-27phospholipids in medium LDL measurementblood low density lipoprotein phospholipid level (CMO:0001568)194489861144898612Human
407037346GWAS686322_Hphospholipids in small LDL measurement QTL GWAS686322 (human)4e-40phospholipids in small LDL measurement 194489861144898612Human
407029603GWAS678579_Hcholesteryl ester measurement QTL GWAS678579 (human)1e-25blood lipid amount (VT:0003949)194489861144898612Human
407039200GWAS688176_Hphospholipids in large LDL measurement QTL GWAS688176 (human)3e-24phospholipids in large LDL measurementblood low density lipoprotein phospholipid level (CMO:0001568)194489861144898612Human
407117539GWAS766515_Hfree cholesterol in IDL measurement QTL GWAS766515 (human)2e-20free cholesterol in IDL measurementblood intermediate density lipoprotein cholesterol level (CMO:0001562)194489861144898612Human
407092466GWAS741442_Hphospholipids:total lipids ratio QTL GWAS741442 (human)2e-17phospholipids:total lipids ratio194489861144898612Human
407115510GWAS764486_Hcholesteryl ester measurement QTL GWAS764486 (human)3e-23blood lipid amount (VT:0003949)194489861144898612Human
407078897GWAS727873_Hphospholipids:total lipids ratio QTL GWAS727873 (human)3e-13phospholipids:total lipids ratio194489861144898612Human
407033334GWAS682310_Hlow density lipoprotein cholesterol measurement QTL GWAS682310 (human)3e-26low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)194489861144898612Human
407038262GWAS687238_Hfree cholesterol in small LDL measurement QTL GWAS687238 (human)1e-31free cholesterol in small LDL measurement 194489861144898612Human
407120313GWAS769289_Htotal lipids in IDL QTL GWAS769289 (human)1e-23total lipids in IDL194489861144898612Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS674459_H GCST90269712 Cholesterol to total lipids in large LDL percentage (UKB data field 23615) 88,329 European ancestry individuals C 0.0409463 4E-12 11.398 rs118170342 0.0820212 cholesterol to total lipids in large LDL percentage (EFO:0022235)
 PMID:36764567
GWAS678423_H GCST90269501 Clinical LDL cholesterol levels (UKB data field 23404) 88,329 European ancestry individuals C 0.0409463 5E-26 25.302 rs118170342 0.127682 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:36764567
GWAS678579_H GCST90269514 Cholesteryl esters in LDL (UKB data field 23417) 88,329 European ancestry individuals C 0.0409463 1E-25 25 rs118170342 0.12719 cholesteryl ester measurement (EFO:0010351)
 PMID:36764567
GWAS679063_H GCST90269616 Cholesterol in very small VLDL (UKB data field 23519) 88,329 European ancestry individuals C 0.0409463 2E-18 17.699 rs118170342 0.103184 cholesterol in very small VLDL measurement (EFO:0022231)
 PMID:36764567
GWAS680229_H GCST90269620 Concentration of IDL particles (UKB data field 23523) 88,329 European ancestry individuals C 0.0409463 4E-26 25.398 rs118170342 0.127043 intermediate density lipoprotein measurement (EFO:0008595)
 PMID:36764567
GWAS682310_H GCST90269502 LDL cholesterol levels (UKB data field 23405) 88,329 European ancestry individuals C 0.0409463 3E-26 25.523 rs118170342 0.128345 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:36764567
GWAS684709_H GCST90269639 Free cholesterol in medium LDL (UKB data field 23542) 88,329 European ancestry individuals C 0.0409463 7E-26 25.155 rs118170342 0.127823 free cholesterol in medium LDL measurement (EFO:0022268)
 PMID:36764567
GWAS685731_H GCST90269644 Cholesterol in small LDL (UKB data field 23547) 88,329 European ancestry individuals C 0.0409463 4E-30 29.398 rs118170342 0.1389 cholesterol in small LDL measurement (EFO:0022227)
 PMID:36764567
GWAS686251_H GCST90269510 Phospholipids in LDL (UKB data field 23413) 88,329 European ancestry individuals C 0.0409463 6E-28 27.222 rs118170342 0.132942 phospholipids in LDL measurement (EFO:0022294)
 PMID:36764567
GWAS686322_H GCST90269643 Phospholipids in small LDL (UKB data field 23546) 88,329 European ancestry individuals C 0.0409463 4E-40 39.398 rs118170342 0.160877 phospholipids in small LDL measurement (EFO:0022297)
 PMID:36764567
GWAS686498_H GCST90269642 Total lipids in small LDL (UKB data field 23545) 88,329 European ancestry individuals C 0.0409463 7E-33 32.155 rs118170342 0.145186 total lipids in small LDL (EFO:0022168)
 PMID:36764567
GWAS687238_H GCST90269646 Free cholesterol in small LDL (UKB data field 23549) 88,329 European ancestry individuals C 0.0409463 1E-31 31 rs118170342 0.142174 free cholesterol in small LDL measurement (EFO:0022271)
 PMID:36764567
None Available GCST90269631 Cholesteryl esters in large LDL (UKB data field 23534) 88,329 European ancestry individuals C 0.0409463 7E-26 25.155 rs118170342 0.126747 cholesteryl ester measurement (EFO:0010351)
 PMID:36764567
GWAS687593_H GCST90269522 Total lipids in LDL (UKB data field 23425) 88,329 European ancestry individuals C 0.0409463 2E-26 25.699 rs118170342 0.129191 total lipids in LDL measurement (EFO:0022308)
 PMID:36764567
GWAS687721_H GCST90269628 Total lipids in large LDL (UKB data field 23531) 88,329 European ancestry individuals C 0.0409463 2E-25 24.699 rs118170342 0.125557 total lipids in large LDL (EFO:0022163)
 PMID:36764567
None Available GCST90269630 Cholesterol in large LDL (UKB data field 23533) 88,329 European ancestry individuals C 0.0409463 1E-25 25 rs118170342 0.126178 cholesterol in large LDL measurement (EFO:0021901)
 PMID:36764567
GWAS688044_H GCST90269636 Phospholipids in medium LDL (UKB data field 23539) 88,329 European ancestry individuals C 0.0409463 1E-27 27 rs118170342 0.132533 phospholipids in medium LDL measurement (EFO:0022183)
 PMID:36764567
GWAS688176_H GCST90269629 Phospholipids in large LDL (UKB data field 23532) 88,329 European ancestry individuals C 0.0409463 3E-24 23.523 rs118170342 0.122708 phospholipids in large LDL measurement (EFO:0022174)
 PMID:36764567
GWAS688795_H GCST90269632 Free cholesterol in large LDL (UKB data field 23535) 88,329 European ancestry individuals C 0.0409463 4E-24 23.398 rs118170342 0.121338 free cholesterol in large LDL measurement (EFO:0022176)
 PMID:36764567
GWAS689686_H GCST90269518 Free cholesterol in LDL (UKB data field 23421) 88,329 European ancestry individuals C 0.0409463 8E-26 25.097 rs118170342 0.126603 free cholesterol in LDL measurement (EFO:0022266)
 PMID:36764567
GWAS727873_H GCST90269696 Phospholipids to total lipids in small VLDL percentage (UKB data field 23599) 88,329 European ancestry individuals C 0.0409463 3E-13 12.523 rs118170342 0.0853418 phospholipids:total lipids ratio (EFO:0020946)
 PMID:36764567
GWAS727954_H GCST90269700 Triglycerides to total lipids in small VLDL percentage (UKB data field 23603) 88,329 European ancestry individuals C 0.0409463 1E-13 13 rs118170342 0.087317 triglycerides to total lipids in small VLDL percentage (EFO:0022338)
 PMID:36764567
GWAS728550_H GCST90269699 Free cholesterol to total lipids in small VLDL percentage (UKB data field 23602) 88,329 European ancestry individuals C 0.0409463 1E-10 10 rs118170342 0.075272 free cholesterol to total lipids in small VLDL percentage (EFO:0022287)
 PMID:36764567
GWAS741442_H GCST90269741 Phospholipids to total lipids in small HDL percentage (UKB data field 23644) 88,329 European ancestry individuals C 0.0409463 2E-17 16.699 rs118170342 0.0997034 phospholipids:total lipids ratio (EFO:0020946)
 PMID:36764567
GWAS764486_H GCST90269624 Cholesteryl esters in IDL (UKB data field 23527) 88,329 European ancestry individuals C 0.0409463 3E-23 22.523 rs118170342 0.116814 cholesteryl ester measurement (EFO:0010351)
 PMID:36764567
GWAS766515_H GCST90269625 Free cholesterol in IDL (UKB data field 23528) 88,329 European ancestry individuals C 0.0409463 2E-20 19.699 rs118170342 0.109076 free cholesterol in IDL measurement (EFO:0022181)
 PMID:36764567
GWAS767703_H GCST90269623 Cholesterol in IDL (UKB data field 23526) 88,329 European ancestry individuals C 0.0409463 9E-23 22.046 rs118170342 0.115558 cholesterol in IDL measurement (EFO:0021899)
 PMID:36764567
GWAS769289_H GCST90269621 Total lipids in IDL (UKB data field 23524) 88,329 European ancestry individuals C 0.0409463 1E-23 23 rs118170342 0.117958 total lipids in IDL (EFO:0022161)
 PMID:36764567
GWAS947160_H GCST90092918 Cholesteryl ester levels in medium VLDL 115,082 European ancestry individuals T 0.959232 2E-33 32.699 rs118170342 0.126664 cholesteryl ester measurement (EFO:0010351)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
None Available GCST90448425 Baseline memory in impaired cognition 4,478 European ancestry males ? NR 0.000002 5.699 rs118170342 0.148884 memory performance (EFO:0004874)
 PMID:37984853
None Available GCST90448451 Memory decline 11,062 European ancestry males ? NR 8E-15 14.097 rs118170342 0.020345 memory performance (EFO:0004874)
 PMID:37984853
None Available GCST90448430 Baseline memory 2,487 African ancestry females ? NR 1E-7 7 rs118170342 0.246245 memory performance (EFO:0004874)
 PMID:37984853
None Available GCST90448418 Baseline memory 11,062 European ancestry males, 880 African ancestry males ? NR 9E-17 16.046 rs118170342 0.178066 memory performance (EFO:0004874)
 PMID:37984853
None Available GCST90448457 Memory decline 2,487 African ancestry females ? NR 1E-7 7 rs118170342 0.029651 memory performance (EFO:0004874)
 PMID:37984853
None Available GCST90448427 Baseline memory 13,154 European ancestry females, 2,487 African ancestry females ? NR 2E-15 14.699 rs118170342 0.16003 memory performance (EFO:0004874)
 PMID:37984853
None Available GCST90448424 Baseline memory 11,062 European ancestry males ? NR 9E-15 14.046 rs118170342 0.173875 memory performance (EFO:0004874)
 PMID:37984853
None Available GCST90448454 Memory decline 13,154 European ancestry females, 2,487 African ancestry females ? NR 3E-19 18.523 rs118170342 0.020482 memory performance (EFO:0004874)
 PMID:37984853
None Available GCST90448445 Memory decline 11,062 European ancestry males, 880 African ancestry males ? NR 2E-17 16.699 rs118170342 0.021426 memory performance (EFO:0004874)
 PMID:37984853
None Available GCST90448433 Baseline memory 13,154 European ancestry females ? NR 4E-10 9.398 rs118170342 0.140275 memory performance (EFO:0004874)
 PMID:37984853
None Available GCST90448452 Memory decline in impaired cognition 4,478 European ancestry males ? NR 6E-9 8.222 rs118170342 0.026231 memory performance (EFO:0004874)
 PMID:37984853
None Available GCST90448460 Memory decline 13,154 European ancestry females ? NR 1E-13 13 rs118170342 0.018623 memory performance (EFO:0004874)
 PMID:37984853
Database Acc Id Source(s)
GWAS Catalog GCST90269620 GWAS Catalog

RGD Curation Notes
Note Type Note Reference