GWAS662356_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS662356_H (mean platelet volume QTL GWAS662356 (human)) Homo sapiens

Symbol: GWAS662356_H
Name: mean platelet volume QTL GWAS662356 (human)
RGD ID: 407013380
Trait: mean platelet volume
Measurement Type: mean platelet volume   (CMO:0001348)    
LOD Score: Not Available
P Value: 6.0E-13
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38197,525,959 - 7,525,960RGD_MAPPER_PIPELINEGRCh38
GRCh37197,590,845 - 7,590,846RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS662356_HHumanmean platelet volume  IAGPrs28377676405850206Based on the EFO term IDGWAS_CATALOGPMID:32888493

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS662356_HHumanmean platelet volume  IAGPrs28377676405850206 GWAS_CATALOGPMID:32888493
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1319026MCOLN1mucolipin TRP cation channel 11975226247534009Human

Position Markers

Peak: (rs28377676)
Human AssemblyChrPosition (strand)Source
GRCh38197,525,959 - 7,525,960RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298499UAE1_HUrinary albumin excretion QTL 1 (human)2.730.0009Urinary albumin excretionurine albumin:creatinine ratio (ACR)19116075902Human
1643451SLIPL6_HSerum lipid level QTL 6 (human)2.190.0008Lipid level19116075902Human
1581534BP76_HBlood pressure QTL 76 (human)20.001Blood pressurepulse pressure19116075902Human
407013380GWAS662356_Hmean platelet volume QTL GWAS662356 (human)6e-13mean platelet volumemean platelet volume (CMO:0001348)1975259597525960Human
1581535BP65_HBlood pressure QTL 65 (human)3.10.001Blood pressurepulse pressure19116075902Human
2314591INSUL4_HInsulin level QTL 4 (human)3.80.000038Insulin levelfasting19116075902Human
1298476BP3_HBlood pressure QTL 3 (human)2.4Blood pressuresystolic19116075902Human
407037821GWAS686797_Hmean platelet volume QTL GWAS686797 (human)3e-12mean platelet volumemean platelet volume (CMO:0001348)1975259597525960Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS662356_H GCST90002349 Mean platelet volume 484,042 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals G 0.801295 6E-13 12.222 rs28377676 N/A mean platelet volume (EFO:0004584)
 PMID:32888493
GWAS686797_H GCST90002395 Mean platelet volume 408,112 British individuals A 0.202541 3E-12 11.523 rs28377676 0.019701052 mean platelet volume (EFO:0004584)
 PMID:32888494
Database Acc Id Source(s)
GWAS Catalog GCST90002349 GWAS Catalog

RGD Curation Notes
Note Type Note Reference