GWAS657789_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS657789_H (C-reactive protein measurement QTL GWAS657789 (human)) Homo sapiens

Symbol: GWAS657789_H
Name: C-reactive protein measurement QTL GWAS657789 (human)
RGD ID: 407008813
Trait: C-reactive protein measurement
Measurement Type: blood C-reactive protein level   (CMO:0003160)    
LOD Score: Not Available
P Value: 9.0E-25
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381651,136,115 - 51,136,116RGD_MAPPER_PIPELINEGRCh38
GRCh371651,170,026 - 51,170,027RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS657789_HHumanblood C-reactive protein level  IAGPrs116971887405850206Based on the EFO term IDGWAS_CATALOGPMID:30388399

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS657789_HHumanC-reactive protein measurement  IAGPrs116971887405850206 GWAS_CATALOGPMID:30388399
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1320515SALL1spalt like transcription factor 1165113598251152334Human

Position Markers

Peak: (rs116971887)
Human AssemblyChrPosition (strand)Source
GRCh381651,136,115 - 51,136,116RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407332422GWAS981398_HIGF-1 measurement QTL GWAS981398 (human)8e-10IGF-1 measurementblood insulin-like growth factor 1 level (CMO:0001297)165113611551136116Human
407061168GWAS710144_HC-reactive protein measurement QTL GWAS710144 (human)2e-121C-reactive protein measurementblood C-reactive protein level (CMO:0003160)165113611551136116Human
407062743GWAS711719_Hred blood cell density measurement QTL GWAS711719 (human)5e-24red blood cell density measurement165113611551136116Human
406930725GWAS579701_HC-reactive protein measurement QTL GWAS579701 (human)4e-105C-reactive protein measurementblood C-reactive protein level (CMO:0003160)165113611551136116Human
407016471GWAS665447_HC-reactive protein measurement QTL GWAS665447 (human)3e-20C-reactive protein measurementblood C-reactive protein level (CMO:0003160)165113611551136116Human
407112081GWAS761057_Herythrocyte count QTL GWAS761057 (human)1e-21erythrocyte countred blood cell count (CMO:0000025)165113611551136116Human
407064296GWAS713272_Hred blood cell density measurement QTL GWAS713272 (human)4e-22red blood cell density measurement165113611551136116Human
407105679GWAS754655_Herythrocyte count QTL GWAS754655 (human)4e-16erythrocyte countred blood cell count (CMO:0000025)165113611551136116Human
406946285GWAS595261_Hhematocrit QTL GWAS595261 (human)2e-12hematocrithematocrit (CMO:0000037)165113611551136116Human
407008813GWAS657789_HC-reactive protein measurement QTL GWAS657789 (human)9e-25C-reactive protein measurementblood C-reactive protein level (CMO:0003160)165113611551136116Human
406979997GWAS628973_Hhemoglobin measurement QTL GWAS628973 (human)5e-09hemoglobin measurementhemoglobin measurement (CMO:0000508)165113611551136116Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS579701_H GCST90179146 C-reactive protein levels (MTAG) 575,531 European ancestry individuals T NR 4E-105 104.398 rs116971887 0.10703 C-reactive protein measurement (EFO:0004458)
 PMID:36376304
GWAS595261_H GCST90002383 Hematocrit 408,112 British individuals T 0.045417 2E-12 11.699 rs116971887 0.03827019 hematocrit (EFO:0004348)
 PMID:32888494
GWAS628973_H GCST90002384 Hemoglobin 408,112 British individuals T 0.045412 5E-9 8.302 rs116971887 0.03196311 hemoglobin measurement (EFO:0004509)
 PMID:32888494
GWAS657789_H GCST007615 C-reactive protein levels 148,164 European ancestry individuals T 0.05 9E-25 24.046 rs116971887 0.118 C-reactive protein measurement (EFO:0004458)
 PMID:30388399
GWAS665447_H GCST007615 C-reactive protein levels 148,164 European ancestry individuals T 0.05 3E-20 19.523 rs116971887 0.113 C-reactive protein measurement (EFO:0004458)
 PMID:30388399
GWAS710144_H GCST009777 C-reactive protein levels 418,642 British ancestry individuals G 0.954751 2E-121 120.699 rs116971887 0.11664 C-reactive protein measurement (EFO:0004458)
 PMID:31900758
GWAS711719_H GCST90002363 Red blood cell count 545,203 European ancestry individuals T 0.045913 5E-24 23.302 rs116971887 0.04532 red blood cell density measurement (EFO:0007978)
 PMID:32888493
GWAS713272_H GCST90002367 Red blood cell count 727,624 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals T 0.0443815 4E-22 21.398 rs116971887 N/A red blood cell density measurement (EFO:0007978)
 PMID:32888493
GWAS754655_H GCST90002403 Red blood cell count 408,112 British individuals T 0.045411 4E-16 15.398 rs116971887 0.044295106 erythrocyte count (EFO:0004305)
 PMID:32888494
GWAS761057_H GCST007069 Red blood cell count approximately 445,000 European ancestry individuals ? NR 1E-21 21 rs116971887 N/A erythrocyte count (EFO:0004305)
 PMID:30595370
None Available GCST90448658 C-reactive protein levels 592 Asian ancestry individuals, 8,819 Black individuals, 8,721 Hispanic or Latin American individuals, 20,333 European ancestry individuals T 0.0364 4E-10 9.398 rs116971887 0.13 C-reactive protein measurement (EFO:0004458)
 PMID:38747556
GWAS981398_H GCST90019511 Insulin-like growth factor 1 levels 340,567 European ancestry individuals, 5,974 African ancestry individuals, 7,283 South Asian ancestry individuals T NR 8E-10 9.097 rs116971887 0.036 IGF-1 measurement (EFO:0004627)
 PMID:33462484
Database Acc Id Source(s)
GWAS Catalog GCST007615 GWAS Catalog

RGD Curation Notes
Note Type Note Reference