GWAS612105_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS612105_H (basophil percentage of leukocytes QTL GWAS612105 (human)) Homo sapiens

Symbol: GWAS612105_H
Name: basophil percentage of leukocytes QTL GWAS612105 (human)
RGD ID: 406963129
Trait: basophil percentage of leukocytes
Measurement Type: blood basophil count to total leukocyte count ratio   (CMO:0000368)    
LOD Score: Not Available
P Value: 8.0E-19
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3886,936,497 - 6,936,498RGD_MAPPER_PIPELINEGRCh38
GRCh3786,794,019 - 6,794,020RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS612105_HHumanblood basophil count to total leukocyte count ratio  IAGPrs2239668405850206Based on the EFO term IDGWAS_CATALOGPMID:32888494

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS612105_HHumanbasophil percentage of leukocytes  IAGPrs2239668405850206 GWAS_CATALOGPMID:32888494
Experimental Data Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1353794DEFA4defensin alpha 4869358206938306Human

Position Markers

Peak: (rs2239668)
Human AssemblyChrPosition (strand)Source
GRCh3886,936,497 - 6,936,498RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407167638GWAS816614_Hneutrophil measurement QTL GWAS816614 (human)4e-40neutrophil measurement869364976936498Human
406963129GWAS612105_Hbasophil percentage of leukocytes QTL GWAS612105 (human)8e-19basophil percentage of leukocytesblood basophil count to total leukocyte count ratio (CMO:0000368)869364976936498Human
407054047GWAS703023_Hmonocyte percentage of leukocytes QTL GWAS703023 (human)4e-17monocyte percentage of leukocytesblood monocyte count to total leukocyte count ratio (CMO:0000374)869364976936498Human
406963644GWAS612620_Hbasophil count QTL GWAS612620 (human)2e-21basophil quantity (VT:0002607)blood basophil count (CMO:0000034)869364976936498Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS612105_H GCST90002380 Basophil percentage of white cells 408,112 British individuals A 0.666719 8E-19 18.097 rs2239668 0.021167787 basophil percentage of leukocytes (EFO:0007992)
 PMID:32888494
GWAS612620_H GCST90002379 Basophil count 408,112 British individuals A 0.666748 2E-21 20.699 rs2239668 0.023237497 basophil count (EFO:0005090)
 PMID:32888494
GWAS703023_H GCST90002394 Monocyte percentage of white cells 408,112 British individuals A 0.666735 4E-17 16.398 rs2239668 0.020049546 monocyte percentage of leukocytes (EFO:0007989)
 PMID:32888494
GWAS816614_H GCST90281222 Neutrophil side scatter 38,341 European ancestry individuals A 0.6644 4E-40 39.398 rs2239668 0.098763 neutrophil measurement (EFO:0803548)
 PMID:37596262
Database Acc Id Source(s)
GWAS Catalog GCST90002380 GWAS Catalog

RGD Curation Notes
Note Type Note Reference