GWAS603043_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS603043_H (forced expiratory volume, response to bronchodilator QTL GWAS603043 (human)) Homo sapiens

Symbol: GWAS603043_H
Name: forced expiratory volume, response to bronchodilator QTL GWAS603043 (human)
RGD ID: 406954067
Trait: forced expiratory volume, response to bronchodilator
Measurement Type: forced expiratory volume   (CMO:0000254)    
LOD Score: Not Available
P Value: 9.0E-8
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381578,599,285 - 78,599,286RGD_MAPPER_PIPELINEGRCh38
GRCh371578,891,627 - 78,891,628RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS603043_HHumanforced expiratory volume  IAGPrs12910984405850206Based on the EFO term IDGWAS_CATALOGPMID:26634245

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS603043_HHumanforced expiratory volume  IAGPrs12910984405850206 GWAS_CATALOGPMID:26634245
GWAS603043_HHumanresponse to bronchodilator  IAGPrs12910984405850206 GWAS_CATALOGPMID:26634245
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
732613CHRNA3cholinergic receptor nicotinic alpha 3 subunit157859305278620996Human

Position Markers

Peak: (rs12910984)
Human AssemblyChrPosition (strand)Source
GRCh381578,599,285 - 78,599,286RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
406954067GWAS603043_Hforced expiratory volume, response to bronchodilator QTL GWAS603043 (human)9e-08forced expiratory volume, response to bronchodilatorforced expiratory volume (CMO:0000254)157859928578599286Human
407268347GWAS917323_Hperipheral arterial disease QTL GWAS917323 (human)9e-10peripheral arterial disease157859928578599286Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS603043_H GCST003262 Post bronchodilator FEV1 10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals A 0.613 9E-8 7.046 rs12910984 0.054 forced expiratory volume (EFO:0004314)
response to bronchodilator (GO:0097366)
 PMID:26634245
GWAS917323_H GCST90061372 Peripheral artery disease in ever smokers 7,404 Finnish ancestry cases, 205,693 Finnish ancestry controls, 7,404 non-Scandinavian ancestry cases, 205,693 non-Scandinavian ancestry controls, 7,404 British ancestry cases, 205,693 British ancestry controls A 0.76 9E-10 9.046 rs12910984 1.15 peripheral arterial disease (EFO:0004265)
 PMID:34601942
Database Acc Id Source(s)
GWAS Catalog GCST003262 GWAS Catalog

RGD Curation Notes
Note Type Note Reference