GWAS600706_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS600706_H (platelet count QTL GWAS600706 (human)) Homo sapiens

Symbol: GWAS600706_H
Name: platelet count QTL GWAS600706 (human)
RGD ID: 406951730
Trait: platelet quantity   (VT:0003179)    
Measurement Type: platelet count   (CMO:0000029)    
LOD Score: Not Available
P Value: 9.0E-15
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh382243,928,975 - 43,928,976RGD_MAPPER_PIPELINEGRCh38
GRCh372244,324,855 - 44,324,856RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS600706_HHumanplatelet count  IAGPrs3747207405850206Based on the EFO term IDGWAS_CATALOGPMID:27863252

Vertebrate Trait
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS600706_HHumanplatelet quantity  IAGPrs3747207405850206Based on the EFO term IDGWAS_CATALOGPMID:27863252

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS600706_HHumanplatelet count  IAGPrs3747207405850206 GWAS_CATALOGPMID:27863252
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement
platelet count  (IAGP)

Vertebrate Trait

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1601958PNPLA3patatin like phospholipase domain containing 3224392380543947582Human

Position Markers

Peak: (rs3747207)
Human AssemblyChrPosition (strand)Source
GRCh382243,928,975 - 43,928,976RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
406996934GWAS645910_Hsex hormone-binding globulin measurement QTL GWAS645910 (human)1e-30sex hormone-binding globulin measurement224392897543928976Human
407082823GWAS731799_Hcholesterol to total lipids in IDL percentage QTL GWAS731799 (human)3e-11cholesterol to total lipids in IDL percentage 224392897543928976Human
406991819GWAS640795_Hmean corpuscular hemoglobin concentration QTL GWAS640795 (human)1e-25mean corpuscular hemoglobin concentrationmean corpuscular hemoglobin concentration (CMO:0000291)224392897543928976Human
407183950GWAS832926_Huric acid measurement QTL GWAS832926 (human)2e-09uric acid measurementblood uric acid level (CMO:0000501)224392897543928976Human
407194716GWAS843692_Hplatelet count QTL GWAS843692 (human)7e-38platelet quantity (VT:0003179)platelet count (CMO:0000029)224392897543928976Human
407331933GWAS980909_Hnon-high density lipoprotein cholesterol measurement QTL GWAS980909 (human)3e-28non-high density lipoprotein cholesterol measurementblood non-high density lipoprotein cholesterol level (CMO:0003967)224392897543928976Human
406966234GWAS615210_Hribonuclease UK114 measurement QTL GWAS615210 (human)1e-12sex hormone-binding globulin measurementblood low density lipoprotein particle diameter (CMO:0002693)224392897543928976Human
407186788GWAS835764_Hlow density lipoprotein cholesterol measurement, phospholipids:total lipids ratio QTL GWAS835764 (human)4e-08low density lipoprotein cholesterol measurement, phospholipids:total lipids ratioblood low density lipoprotein cholesterol level (CMO:0000053)224392897543928976Human
407213284GWAS862260_Hlow density lipoprotein particle size measurement QTL GWAS862260 (human)1e-18low density lipoprotein particle size measurementblood low density lipoprotein particle diameter (CMO:0002693)224392897543928976Human
407096552GWAS745528_Hcholesteryl esters to total lipids in large VLDL percentage QTL GWAS745528 (human)1e-10cholesteryl esters to total lipids in large VLDL percentage 224392897543928976Human
407164904GWAS813880_Htriglyceride measurement QTL GWAS813880 (human)5e-12triglyceride measurementblood protein measurement (CMO:0000028)224392897543928976Human
407081326GWAS730302_Hcholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement QTL GWAS730302 (human)2e-14cholesteryl esters:total lipids ratio, intermediate density lipoprotein measurementblood intermediate density lipoprotein cholesterol level (CMO:0001562)224392897543928976Human
406944753GWAS593729_Hprotein measurement QTL GWAS593729 (human)1e-13total cholesterol measurementblood total cholesterol level (CMO:0000051)224392897543928976Human
407240447GWAS889423_Htriglyceride measurement, intermediate density lipoprotein measurement QTL GWAS889423 (human)3e-09triglyceride measurementblood high density lipoprotein cholesterol level (CMO:0000052)224392897543928976Human
407220095GWAS869071_Htype 2 diabetes mellitus QTL GWAS869071 (human)9e-18type 2 diabetes mellitus224392897543928976Human
407269885GWAS918861_Hsex hormone-binding globulin measurement QTL GWAS918861 (human)8e-13sex hormone-binding globulin measurement224392897543928976Human
407167110GWAS816086_Hserum alanine aminotransferase measurement QTL GWAS816086 (human)6e-09very low density lipoprotein cholesterol measurement, phospholipid measurementblood very low density lipoprotein cholesterol level (CMO:0000648)224392897543928976Human
407097216GWAS746192_Htriglycerides to total lipids in large VLDL percentage QTL GWAS746192 (human)4e-13triglycerides to total lipids in large VLDL percentage 224392897543928976Human
407251842GWAS900818_Hbody fat percentage QTL GWAS900818 (human)8e-09blood triglyceride amount (VT:0002644)body fat percentage (CMO:0000302)224392897543928976Human
407182339GWAS831315_Hliver neoplasm QTL GWAS831315 (human)4e-14total cholesterol measurementblood total cholesterol level (CMO:0000051)224392897543928976Human
407316623GWAS965599_Hlow density lipoprotein cholesterol measurement QTL GWAS965599 (human)6e-13low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)224392897543928976Human
407217676GWAS866652_Hgout QTL GWAS866652 (human)5e-21gout224392897543928976Human
407276812GWAS925788_Haspartate aminotransferase measurement QTL GWAS925788 (human)6e-08aspartate aminotransferase measurementblood aspartate aminotransferase activity level (CMO:0000580)224392897543928976Human
407269901GWAS918877_Hcholesterol:total lipids ratio, intermediate density lipoprotein measurement QTL GWAS918877 (human)1e-14cholesterol:total lipids ratio, intermediate density lipoprotein measurementblood intermediate density lipoprotein cholesterol level (CMO:0001562)224392897543928976Human
407167112GWAS816088_Haspartate aminotransferase measurement QTL GWAS816088 (human)2e-12aspartate aminotransferase measurementblood aspartate aminotransferase activity level (CMO:0000580)224392897543928976Human
407312277GWAS961253_Hdiglyceride measurement QTL GWAS961253 (human)2e-18diglyceride measurement224392897543928976Human
407324692GWAS973668_Htotal cholesterol measurement QTL GWAS973668 (human)1e-11total cholesterol measurementblood total cholesterol level (CMO:0000051)224392897543928976Human
407193617GWAS842593_Haspartate aminotransferase measurement QTL GWAS842593 (human)1e-91aspartate aminotransferase measurementblood aspartate aminotransferase activity level (CMO:0000580)224392897543928976Human
407312273GWAS961249_Hdiglyceride measurement QTL GWAS961249 (human)3e-08diglyceride measurement224392897543928976Human
407326491GWAS975467_Htyrosine measurement QTL GWAS975467 (human)7e-09tyrosine measurement224392897543928976Human
407216410GWAS865386_Hnon-alcoholic fatty liver disease QTL GWAS865386 (human)2e-87non-alcoholic fatty liver disease224392897543928976Human
407086883GWAS735859_Hphospholipids:total lipids ratio QTL GWAS735859 (human)2e-21serum alanine aminotransferase measurementserum alanine aminotransferase activity level (CMO:0000575)224392897543928976Human
407261990GWAS910966_Haspartate aminotransferase measurement QTL GWAS910966 (human)6e-78aspartate aminotransferase measurementblood aspartate aminotransferase activity level (CMO:0000580)224392897543928976Human
407316006GWAS964982_Hcholesteryl ester measurement, high density lipoprotein cholesterol measurement QTL GWAS964982 (human)5e-10blood lipid amount (VT:0003949)blood high density lipoprotein cholesterol level (CMO:0000052)224392897543928976Human
407329957GWAS978933_Hdiglyceride measurement QTL GWAS978933 (human)4e-12diglyceride measurement224392897543928976Human
407287973GWAS936949_Hserum alanine aminotransferase measurement QTL GWAS936949 (human)2e-344serum alanine aminotransferase measurementserum alanine aminotransferase activity level (CMO:0000575)224392897543928976Human
406961442GWAS610418_Hprotein measurement QTL GWAS610418 (human)2e-15protein measurement224392897543928976Human
407185441GWAS834417_Hvery low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio QTL GWAS834417 (human)6e-12very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratioblood very low density lipoprotein cholesterol level (CMO:0000648)224392897543928976Human
407186976GWAS835952_Htriglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement QTL GWAS835952 (human)2e-13triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)224392897543928976Human
407051300GWAS700276_Hnon-alcoholic fatty liver disease QTL GWAS700276 (human)5e-08total cholesterol measurementblood total cholesterol level (CMO:0000051)224392897543928976Human
407097387GWAS746363_Htotal cholesterol measurement QTL GWAS746363 (human)4e-09total cholesterol measurementblood total cholesterol level (CMO:0000051)224392897543928976Human
407261999GWAS910975_Hserum alanine aminotransferase measurement QTL GWAS910975 (human)4e-82serum alanine aminotransferase measurementserum alanine aminotransferase activity level (CMO:0000575)224392897543928976Human
407313835GWAS962811_Hlow density lipoprotein cholesterol measurement QTL GWAS962811 (human)8e-18low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)224392897543928976Human
407272106GWAS921082_Htype 2 diabetes mellitus QTL GWAS921082 (human)4e-21type 2 diabetes mellitus224392897543928976Human
407244073GWAS893049_Hliver neoplasm QTL GWAS893049 (human)2e-08liver integrity trait (VT:0010547)liver fibrotic lesion measurement (CMO:0001088)224392897543928976Human
407332023GWAS980999_Hhigh density lipoprotein cholesterol measurement QTL GWAS980999 (human)5e-09obsolete_red blood cell distribution widthred blood cell distribution width- standard deviation (CMO:0003232)224392897543928976Human
407244983GWAS893959_Hsex hormone-binding globulin measurement QTL GWAS893959 (human)7e-10sex hormone-binding globulin measurement224392897543928976Human
406951730GWAS600706_Hplatelet count QTL GWAS600706 (human)9e-15platelet quantity (VT:0003179)platelet count (CMO:0000029)224392897543928976Human
406996406GWAS645382_Hsex hormone-binding globulin measurement QTL GWAS645382 (human)4e-27sex hormone-binding globulin measurement224392897543928976Human
407318962GWAS967938_Htotal cholesterol measurement, high density lipoprotein cholesterol measurement QTL GWAS967938 (human)1e-08total cholesterol measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)224392897543928976Human
407257905GWAS906881_Hliver fibrosis measurement QTL GWAS906881 (human)2e-16liver integrity trait (VT:0010547)liver fibrotic lesion measurement (CMO:0001088)224392897543928976Human
407241016GWAS889992_Hcholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement QTL GWAS889992 (human)2e-11diglyceride measurementblood intermediate density lipoprotein cholesterol level (CMO:0001562)224392897543928976Human
407264825GWAS913801_Hliver fibrosis measurement QTL GWAS913801 (human)2e-62liver integrity trait (VT:0010547)liver fibrotic lesion measurement (CMO:0001088)224392897543928976Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS593729_H GCST90247557 Fructose-bisphosphate aldolase B levels 10,708 European ancestry individuals A 0.22 1E-13 13 rs3747207 0.114 protein measurement (EFO:0004747)
 PMID:34648354
GWAS600706_H GCST004603 Platelet count 166,066 European ancestry individuals A 0.2138 9E-15 14.046 rs3747207 0.03453617 platelet count (EFO:0004309)
 PMID:27863252
None Available GCST004621 Red cell distribution width 171,529 European ancestry individuals A 0.2139 5E-9 8.302 rs3747207 0.02530545 Red cell distribution width (EFO:0009188)
 PMID:27863252
GWAS610418_H GCST90246433 Alcohol dehydrogenase 1A levels 10,708 European ancestry individuals A 0.22 2E-15 14.699 rs3747207 0.125 protein measurement (EFO:0004747)
 PMID:34648354
GWAS615210_H GCST90249398 Ribonuclease UK114 levels 10,708 European ancestry individuals A 0.22 1E-12 12 rs3747207 0.113 ribonuclease UK114 measurement (EFO:0802020)
 PMID:34648354
GWAS640795_H GCST90002322 Mean corpuscular hemoglobin 486,823 European ancestry individuals A 0.215331 1E-25 25 rs3747207 0.02444 mean corpuscular hemoglobin concentration (EFO:0004528)
 PMID:32888493
GWAS645382_H GCST90012107 Sex hormone-binding globulin levels 189,473 European ancestry women A 0.214383 4E-27 26.398 rs3747207 0.018691 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:32042192
GWAS645910_H GCST90012106 Sex hormone-binding globulin levels adjusted for BMI 188,908 European ancestry women A 0.214383 1E-30 30 rs3747207 0.0172527 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:32042192
None Available GCST90269529 Average diameter for LDL particles (UKB data field 23432) 88,329 European ancestry individuals A 0.214398 1E-12 12 rs3747207 0.0401093 low density lipoprotein particle size measurement (EFO:0008593)
 PMID:36764567
GWAS700276_H GCST90271929 Nonalcoholic fatty liver disease 2,757 European ancestry cases, 460,161 European ancestry controls ? NR 5E-8 7.302 rs3747207 N/A non-alcoholic fatty liver disease (EFO:0003095)
 PMID:36986172
None Available GCST90245325 N-acetylmethionine levels 14,296 European ancestry individuals A 0.2181 1E-12 12 rs3747207 0.08685526 N-acetylmethionine measurement (EFO:0021427)
 PMID:36357675
GWAS730302_H GCST90301978 Cholesteryl esters to total lipids ratio in IDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.2308 2E-14 13.699 rs3747207 0.0361 cholesteryl esters:total lipids ratio (EFO:0020944)
intermediate density lipoprotein measurement (EFO:0008595)
 PMID:38448586
GWAS731799_H GCST90269707 Cholesterol to total lipids in IDL percentage (UKB data field 23610) 88,329 European ancestry individuals A 0.214398 3E-11 10.523 rs3747207 0.0375538 cholesterol to total lipids in IDL percentage (EFO:0022233)
 PMID:36764567
GWAS735859_H GCST90269706 Phospholipids to total lipids in IDL percentage (UKB data field 23609) 88,329 European ancestry individuals A 0.214398 2E-21 20.699 rs3747207 0.0549596 phospholipids:total lipids ratio (EFO:0020946)
 PMID:36764567
GWAS745528_H GCST90269688 Cholesteryl esters to total lipids in large VLDL percentage (UKB data field 23591) 88,321 European ancestry individuals A 0.214395 1E-10 10 rs3747207 0.0356145 cholesteryl esters to total lipids in large VLDL percentage (EFO:0022250)
 PMID:36764567
GWAS746192_H GCST90269690 Triglycerides to total lipids in large VLDL percentage (UKB data field 23593) 88,321 European ancestry individuals A 0.214395 4E-13 12.398 rs3747207 0.0418537 triglycerides to total lipids in large VLDL percentage (EFO:0022332)
 PMID:36764567
None Available GCST007143 Total cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G 0.781 5E-8 7.302 rs3747207 0.032 total cholesterol measurement (EFO:0004574)
 PMID:29507422
GWAS746363_H GCST007143 Total cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G NR 4E-9 8.398 rs3747207 0.03 total cholesterol measurement (EFO:0004574)
 PMID:29507422
GWAS813880_H GCST90060991 Triacylglycerol(56:6)_[M+NH4]1+ levels 5,662 Pakistani ancestry individuals G NR 5E-12 11.302 rs3747207 0.0639 triglyceride measurement (EFO:0004530)
 PMID:34503513
GWAS816086_H GCST90013663 Alanine aminotransferase levels 387,859 British ancestry individuals, 10,635 Asian or Asian British individuals, 7,468 Black or Black British individuals, 2,338 Chinese ancestry individuals ? NR 6E-9 8.222 rs3747207 0.0872815 serum alanine aminotransferase measurement (EFO:0004735)
 PMID:34315874
GWAS816088_H GCST90013664 Aspartate aminotransferase levels 386,570 British ancestry individuals, 10,617 Asian or Asian British individuals, 7,426 Black or Black British individuals, 2,321 Chinese ancestry individuals ? NR 2E-12 11.699 rs3747207 0.110671364 aspartate aminotransferase measurement (EFO:0004736)
 PMID:34315874
GWAS831315_H GCST90018858 Hepatic cancer 379 European ancestry cases, 475,259 European ancestry controls, 2,122 East Asian ancestry cases, 159,201 East Asian ancestry controls A NR 4E-14 13.398 rs3747207 0.2256 liver neoplasm (EFO:1001513)
 PMID:34594039
GWAS832926_H GCST90018757 Serum uric acid levels 129,405 East Asian ancestry individuals A 0.45251 2E-9 8.699 rs3747207 0.0212271 uric acid measurement (EFO:0004761)
 PMID:34594039
GWAS834417_H GCST90092871 Cholesteryl esters to total lipids ratio in large VLDL 115,071 European ancestry individuals G 0.785005 6E-12 11.222 rs3747207 0.0330817 very low density lipoprotein cholesterol measurement (EFO:0008317)
cholesteryl esters:total lipids ratio (EFO:0020944)
 PMID:35213538
GWAS835764_H GCST90092865 Phospholipids to total lipids ratio in large LDL 115,082 European ancestry individuals G 0.785004 4E-8 7.398 rs3747207 0.027621 low density lipoprotein cholesterol measurement (EFO:0004611)
phospholipids:total lipids ratio (EFO:0020946)
 PMID:35213538
GWAS835952_H GCST90092879 Triglycerides to total lipids ratio in large VLDL 115,071 European ancestry individuals G 0.785005 2E-13 12.699 rs3747207 0.0367849 triglycerides:total lipids ratio (EFO:0020947)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
GWAS842593_H GCST90134477 Aspartate aminotransferase levels 5,694 African ancestry individuals, 1,988 East Asian ancestry individuals, 336,298 European ancestry individuals, 6,036 South Asian ancestry individuals ? NR 1E-91 91 rs3747207 N/A aspartate aminotransferase measurement (EFO:0004736)
 PMID:35810165
GWAS843692_H GCST90018749 Platelet count 148,623 East Asian ancestry individuals A 0.453285 7E-38 37.155 rs3747207 0.0429808 platelet count (EFO:0004309)
 PMID:34594039
None Available GCST90104297 Sex hormone-binding globulin levels 4,522 African ancestry individuals, 196,901 European ancestry individuals ? NR 1E-12 12 rs3747207 7.133 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:35192695
None Available GCST90060994 Triacylglycerol(56:5)_[M+NH4]1+ levels 5,662 Pakistani ancestry individuals A NR 5E-12 11.302 rs3747207 0.1748 triglyceride measurement (EFO:0004530)
 PMID:34503513
None Available GCST90129603 Chronic elevation of alanine aminotransferase (cALT) levels 23,977 African American cases, 13,387 African American controls A 0.135 2E-21 20.699 rs3747207 0.213 serum alanine aminotransferase measurement (EFO:0004735)
 PMID:35654975
None Available GCST90087111 Serum levels of protein ARFIP2 5,364 Icelandic ancestry individuals A 0.2298 5E-12 11.302 rs3747207 0.152786 blood protein measurement (EFO:0007937)
 PMID:35078996
GWAS862260_H GCST90092889 Average diameter for LDL particles 115,082 European ancestry individuals G 0.785004 1E-18 18 rs3747207 0.0432358 low density lipoprotein particle size measurement (EFO:0008593)
 PMID:35213538
GWAS865386_H GCST90054782 Nonalcoholic fatty liver disease 4,761 European ancestry cases, 373,227 European ancestry controls A 0.215 2E-87 86.699 rs3747207 1.45 non-alcoholic fatty liver disease (EFO:0003095)
 PMID:34535985
GWAS866652_H GCST90399702 Gout 557 Admixed American ancestry cases, 17,629 Admixed American ancestry controls, 533 South Asian ancestry cases, 30,288 South Asian ancestry controls, 1,312 African ancestry cases, 33,902 African ancestry controls, 10,425 East Asian ancestry cases, 338,934 East Asian ancestry controls, 24,278 European ancestry cases, 1,027,375 European ancestry controls A 0.2668 5E-21 20.302 rs3747207 0.087546 gout (EFO:0004274)
 PMID:36777996
GWAS869071_H GCST010555 Type 2 diabetes 148,726 European ancestry cases, 965,732 European ancestry controls G 0.7791 9E-18 17.046 rs3747207 0.0471 PMID:32541925
GWAS889423_H GCST90092841 Triglyceride levels in IDL 115,082 European ancestry individuals G 0.785004 3E-9 8.523 rs3747207 0.0292799 triglyceride measurement (EFO:0004530)
intermediate density lipoprotein measurement (EFO:0008595)
 PMID:35213538
GWAS889992_H GCST90092834 Cholesteryl esters to total lipids ratio in IDL 115,082 European ancestry individuals G 0.785004 2E-11 10.699 rs3747207 0.0329961 cholesteryl esters:total lipids ratio (EFO:0020944)
intermediate density lipoprotein measurement (EFO:0008595)
 PMID:35213538
GWAS893049_H GCST90018638 Hepatic cancer 2,122 East Asian ancestry cases, 159,201 East Asian ancestry controls A 0.45223993 2E-8 7.699 rs3747207 0.17805915 liver neoplasm (EFO:1001513)
 PMID:34594039
GWAS893959_H GCST90104277 Sex hormone-binding globulin levels in postmenopausal women 92,911 European ancestry individuals A 0.214518 7E-10 9.155 rs3747207 0.0348788 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:35192695
GWAS900818_H GCST90432179 Body fat percentage (adjusted for testosterone and SHBG) 157,937 British ancestry males ? NR 8E-9 8.097 rs3747207 0.13 body fat percentage (EFO:0007800)
 PMID:37867527
GWAS906881_H GCST90011736 Fibrosis-4 index in high alcohol intake 33,324 British ancestry individuals ? 0.2145 2E-16 15.699 rs3747207 0.01112 liver fibrosis measurement (EFO:0010576)
 PMID:32561361
GWAS910966_H GCST90011737 Aspartate transaminase levels in high alcohol intake 34,101 British ancestry individuals ? 0.2145 6E-78 77.222 rs3747207 0.02303 aspartate aminotransferase measurement (EFO:0004736)
 PMID:32561361
GWAS910975_H GCST90011738 Alanine transaminase levels in high alcohol intake 34,238 British ancestry individuals ? 0.2145 4E-82 81.398 rs3747207 0.03319 serum alanine aminotransferase measurement (EFO:0004735)
 PMID:32561361
None Available GCST90011734 Forns index in high alcohol intake 33,437 British ancestry individuals ? 0.2145 2E-8 7.699 rs3747207 0.003215 liver fibrosis measurement (EFO:0010576)
 PMID:32561361
GWAS913801_H GCST90011735 Aspartate aminotransferase platelet ratio index in high alcohol intake 33,330 British ancestry individuals ? 0.2145 2E-62 61.699 rs3747207 0.02784 liver fibrosis measurement (EFO:0010576)
 PMID:32561361
GWAS918861_H GCST90104273 Sex hormone-binding globulin levels 196,901 European ancestry individuals A 0.214518 8E-13 12.097 rs3747207 0.0277217 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:35192695
GWAS918877_H GCST90092832 Cholesterol to total lipids ratio in IDL 115,082 European ancestry individuals G 0.785004 1E-14 14 rs3747207 0.037818 cholesterol:total lipids ratio (EFO:0020943)
intermediate density lipoprotein measurement (EFO:0008595)
 PMID:35213538
GWAS921082_H GCST010557 Type 2 diabetes 148,726 European ancestry cases, 24,646 African American cases, 8,616 Hispanic cases, 46,511 Asian ancestry cases, 965,732 European ancestry controls, 31,446 African American controls, 11,829 Hispanic controls, 169,776 Asian ancestry controls G 0.7178 4E-21 20.398 rs3747207 0.0412 PMID:32541925
None Available GCST007381 Alanine aminotransferase levels in excessive alcohol consumption 951 individuals ? NR 3E-9 8.523 rs3747207 0.0238 serum alanine aminotransferase measurement (EFO:0004735)
 PMID:30589442
GWAS925788_H GCST007377 Aspartate aminotransferase levels in excessive alcohol consumption 951 individuals ? NR 6E-8 7.222 rs3747207 0.0143 aspartate aminotransferase measurement (EFO:0004736)
 PMID:30589442
GWAS936949_H GCST90018943 Alanine aminotransferase levels 344,136 European ancestry individuals, 150,545 East Asian ancestry individuals A NR 2E-344 343.699 rs3747207 0.0844 serum alanine aminotransferase measurement (EFO:0004735)
 PMID:34594039
None Available GCST90092951 Concentration of small HDL particles 115,082 European ancestry individuals G 0.785004 3E-9 8.523 rs3747207 0.0297501 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
None Available GCST90239664 Triglyceride levels 1,320,016 European ancestry individuals A 0.222259 3E-9 8.523 rs3747207 0.0121357 triglyceride measurement (EFO:0004530)
 PMID:34887591
GWAS961249_H GCST90024573 Alkyldiacylglycerol (O-50:1) [NL-16:0] levels 4,492 European ancestry individuals A NR 3E-8 7.523 rs3747207 0.144 diglyceride measurement (EFO:0010223)
 PMID:35668104
GWAS961253_H GCST90024575 Alkyldiacylglycerol (O-52:2) [NL-16:0] levels 4,492 European ancestry individuals A NR 2E-18 17.699 rs3747207 0.228 diglyceride measurement (EFO:0010223)
 PMID:35668104
None Available GCST90024570 Triacylglycerol (56:6) [NL-20:4] levels 4,492 European ancestry individuals A NR 8E-9 8.097 rs3747207 0.151 triacylglycerol 56:6 measurement (EFO:0010433)
 PMID:35668104
GWAS962811_H GCST90239655 Low density lipoprotein cholesterol levels 40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals ? NR 8E-18 17.097 rs3747207 N/A low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:34887591
GWAS964982_H GCST90092946 Cholesteryl ester levels in small HDL 115,082 European ancestry individuals G 0.785004 5E-10 9.302 rs3747207 0.0314014 cholesteryl ester measurement (EFO:0010351)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS965599_H GCST90239658 Low density lipoprotein cholesterol levels 1,320,016 European ancestry individuals A 0.222288 6E-13 12.222 rs3747207 0.0139089 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:34887591
GWAS967938_H GCST90092944 Cholesterol levels in small HDL 115,082 European ancestry individuals G 0.785004 1E-8 8 rs3747207 0.0285307 total cholesterol measurement (EFO:0004574)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
None Available GCST90239677 Total cholesterol levels 48,057 Hispanic individuals A 0.445102 4E-14 13.398 rs3747207 0.0585898 total cholesterol measurement (EFO:0004574)
 PMID:34887591
GWAS973668_H GCST90239675 Total cholesterol levels 146,492 East Asian ancestry individuals A 0.421125 1E-11 11 rs3747207 0.0278063 total cholesterol measurement (EFO:0004574)
 PMID:34887591
GWAS975467_H GCST90092993 Tyrosine levels 114,913 European ancestry individuals G 0.784966 7E-9 8.155 rs3747207 0.0288532 tyrosine measurement (EFO:0005058)
 PMID:35213538
None Available GCST90024606 Total Alkyldiacylglycerol levels 4,492 European ancestry individuals A NR 2E-11 10.699 rs3747207 0.175 diglyceride measurement (EFO:0010223)
 PMID:35668104
GWAS978933_H GCST90025814 Alkyldiacylglycerol (O-52:2) [NL-16:0] levels 4,492 European ancestry individuals A NR 4E-12 11.398 rs3747207 0.181 diglyceride measurement (EFO:0010223)
 PMID:35668104
GWAS980909_H GCST90239667 Non-HDL cholesterol levels 40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals ? NR 3E-28 27.523 rs3747207 N/A non-high density lipoprotein cholesterol measurement (EFO:0005689)
 PMID:34887591
GWAS980999_H GCST90018956 HDL cholesterol 315,133 European ancestry individuals, 74,970 East Asian ancestry individuals A NR 5E-9 8.302 rs3747207 0.014 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:34594039
None Available GCST90093036 Phospholipid levels in very small VLDL 115,082 European ancestry individuals G 0.785004 6E-9 8.222 rs3747207 0.0286469 very low density lipoprotein cholesterol measurement (EFO:0008317)
phospholipid measurement (EFO:0004639)
 PMID:35213538
None Available GCST90018974 Total cholesterol levels 344,278 European ancestry individuals, 135,808 East Asian ancestry individuals A NR 1E-13 13 rs3747207 0.0165 total cholesterol measurement (EFO:0004574)
 PMID:34594039
Database Acc Id Source(s)
GWAS Catalog GCST004603 GWAS Catalog

RGD Curation Notes
Note Type Note Reference