GWAS596700_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS596700_H (eosinophil percentage of leukocytes QTL GWAS596700 (human)) Homo sapiens

Symbol: GWAS596700_H
Name: eosinophil percentage of leukocytes QTL GWAS596700 (human)
RGD ID: 406947724
Trait: eosinophil percentage of leukocytes
Measurement Type: blood eosinophil count to total leukocyte count ratio   (CMO:0000369)    
LOD Score: Not Available
P Value: 3.0E-21
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3810113,588,287 - 113,588,288RGD_MAPPER_PIPELINEGRCh38
GRCh3710115,348,046 - 115,348,047RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS596700_HHumanblood eosinophil count to total leukocyte count ratio  IAGPrs7080536405850206Based on the EFO term IDGWAS_CATALOGPMID:32888494

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS596700_HHumaneosinophil percentage of leukocytes  IAGPrs7080536405850206 GWAS_CATALOGPMID:32888494
Experimental Data Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1350340HABP2hyaluronan binding protein 210113550831113589602Human

Position Markers

Peak: (rs7080536)
Human AssemblyChrPosition (strand)Source
GRCh3810113,588,287 - 113,588,288RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407053123GWAS702099_Heosinophil count QTL GWAS702099 (human)3e-18eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)10113588287113588288Human
406946691GWAS595667_Hhistone H1.2 measurement QTL GWAS595667 (human)9e-17histone H1.2 measurement10113588287113588288Human
407006721GWAS655697_Hcardiac troponin I measurement QTL GWAS655697 (human)8e-08cardiac troponin I measurementblood troponin level (CMO:0001283)10113588287113588288Human
406972610GWAS621586_Hsprouty-related, EVH1 domain-containing protein 1 measurement QTL GWAS621586 (human)2e-21sprouty-related, EVH1 domain-containing protein 1 measurement10113588287113588288Human
406953991GWAS602967_Heosinophil count QTL GWAS602967 (human)7e-09eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)10113588287113588288Human
406953928GWAS602904_Hprotein measurement QTL GWAS602904 (human)3e-20protein measurement10113588287113588288Human
407199881GWAS848857_Hblood protein measurement QTL GWAS848857 (human)5e-86blood protein measurementblood protein measurement (CMO:0000028)10113588287113588288Human
406949325GWAS598301_H60S ribosomal protein L30 measurement QTL GWAS598301 (human)2e-1560S ribosomal protein L30 measurement10113588287113588288Human
407333258GWAS982234_Heosinophil count QTL GWAS982234 (human)5e-11eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)10113588287113588288Human
406947724GWAS596700_Heosinophil percentage of leukocytes QTL GWAS596700 (human)3e-21eosinophil percentage of leukocytesblood eosinophil count to total leukocyte count ratio (CMO:0000369)10113588287113588288Human
406894160GWAS543136_Hgastrin-releasing peptide measurement QTL GWAS543136 (human)4e-26gastrin-releasing peptide measurement10113588287113588288Human
406952787GWAS601763_Htransformer-2 protein homolog beta measurement QTL GWAS601763 (human)3e-23transformer-2 protein homolog beta measurement10113588287113588288Human
406969362GWAS618338_Hlysophosphatidylcholine acyltransferase 2 measurement QTL GWAS618338 (human)5e-22lysophosphatidylcholine acyltransferase 2 measurement10113588287113588288Human
406939218GWAS588194_Hinterferon gamma receptor 1 measurement QTL GWAS588194 (human)6e-14interferon gamma receptor 1 measurement10113588287113588288Human
406890647GWAS539623_HC-type lectin domain family 5 member A measurement QTL GWAS539623 (human)6e-63C-type lectin domain family 5 member A measurement10113588287113588288Human
406968600GWAS617576_Heosinophil percentage of leukocytes QTL GWAS617576 (human)2e-09eosinophil percentage of leukocytesblood eosinophil count to total leukocyte count ratio (CMO:0000369)10113588287113588288Human
407111320GWAS760296_Heosinophil count QTL GWAS760296 (human)2e-18eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)10113588287113588288Human
407199579GWAS848555_Hinterferon gamma receptor 1 measurement QTL GWAS848555 (human)4e-31interferon gamma receptor 1 measurement10113588287113588288Human
407215845GWAS864821_Hcardiac troponin I measurement QTL GWAS864821 (human)1e-12cardiac troponin I measurementblood troponin level (CMO:0001283)10113588287113588288Human
406942115GWAS591091_Heosinophil count QTL GWAS591091 (human)1e-18eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)10113588287113588288Human
406944555GWAS593531_HC-type lectin domain family 2 member A measurement QTL GWAS593531 (human)5e-43C-type lectin domain family 2 member A measurement10113588287113588288Human
407056815GWAS705791_Heosinophil count QTL GWAS705791 (human)6e-16eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)10113588287113588288Human
407114089GWAS763065_Hprotein measurement QTL GWAS763065 (human)4e-10protein measurement10113588287113588288Human
406951852GWAS600828_Hprotein measurement QTL GWAS600828 (human)2e-12protein measurement10113588287113588288Human
407214964GWAS863940_Hblood protein measurement QTL GWAS863940 (human)5e-74blood protein measurementblood protein measurement (CMO:0000028)10113588287113588288Human
406893051GWAS542027_Hinterferon gamma receptor 1 measurement QTL GWAS542027 (human)4e-24interferon gamma receptor 1 measurement10113588287113588288Human
407014973GWAS663949_Hfactor VII activating protease measurement QTL GWAS663949 (human)7e-142factor VII activating protease measurement10113588287113588288Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS539623_H GCST90240515 C-type lectin domain family 5 member A levels (CLEC5A.8282.15.3) 3,301 European ancestry individuals A 0.044 6E-63 62.222 rs7080536 1.01 C-type lectin domain family 5 member A measurement (EFO:0801436)
 PMID:29875488
GWAS542027_H GCST90241555 Interferon gamma receptor 1 levels (IFNGR1.5825.49.3) 3,301 European ancestry individuals A 0.044 4E-24 23.398 rs7080536 0.63 interferon gamma receptor 1 measurement (EFO:0020484)
 PMID:29875488
GWAS543136_H GCST90241242 Gastrin-releasing peptide levels (GRP.8339.72.3) 3,301 European ancestry individuals A 0.044 4E-26 25.398 rs7080536 0.65 gastrin-releasing peptide measurement (EFO:0022000)
 PMID:29875488
GWAS588194_H GCST90247998 Interferon gamma receptor 1 levels 10,708 European ancestry individuals A 0.04 6E-14 13.222 rs7080536 0.242 interferon gamma receptor 1 measurement (EFO:0020484)
 PMID:34648354
GWAS591091_H GCST90002298 Eosinophil counts 474,237 European ancestry individuals A 0.043176 1E-18 18 rs7080536 0.043694 eosinophil count (EFO:0004842)
 PMID:32888493
GWAS593531_H GCST90247049 C-type lectin domain family 2 member A levels 10,708 European ancestry individuals A 0.04 5E-43 42.302 rs7080536 0.432 C-type lectin domain family 2 member A measurement (EFO:0802344)
 PMID:34648354
GWAS595667_H GCST90247891 Histone H1.2 levels 10,708 European ancestry individuals A 0.04 9E-17 16.046 rs7080536 0.263 histone H1.2 measurement (EFO:0021966)
 PMID:34648354
GWAS596700_H GCST90002382 Eosinophil percentage of white cells 408,112 British individuals A 0.043277 3E-21 20.523 rs7080536 0.05211327 eosinophil percentage of leukocytes (EFO:0007991)
 PMID:32888494
GWAS598301_H GCST90249327 60S ribosomal protein L30 levels 10,708 European ancestry individuals A 0.04 2E-15 14.699 rs7080536 0.244 60S ribosomal protein L30 measurement (EFO:0801337)
 PMID:34648354
GWAS600828_H GCST90248290 Protein lin-7 homolog A levels 10,708 European ancestry individuals A 0.04 2E-12 11.699 rs7080536 0.232 protein measurement (EFO:0004747)
 PMID:34648354
GWAS601763_H GCST90249755 Transformer-2 protein homolog beta levels 10,708 European ancestry individuals A 0.04 3E-23 22.523 rs7080536 0.331 transformer-2 protein homolog beta measurement (EFO:0802143)
 PMID:34648354
GWAS602904_H GCST90246898 Cholecystokinin levels 10,708 European ancestry individuals A 0.04 3E-20 19.523 rs7080536 0.301 protein measurement (EFO:0004747)
 PMID:34648354
GWAS602967_H GCST004606 Eosinophil counts 172,275 European ancestry individuals A 0.0441 7E-9 8.155 rs7080536 0.05103154 eosinophil count (EFO:0004842)
 PMID:27863252
GWAS617576_H GCST004600 Eosinophil percentage of white cells 172,378 European ancestry individuals A 0.0441 2E-9 8.699 rs7080536 0.05257079 eosinophil percentage of leukocytes (EFO:0007991)
 PMID:27863252
GWAS618338_H GCST90248247 Lysophosphatidylcholine acyltransferase 2 levels 10,708 European ancestry individuals A 0.04 5E-22 21.302 rs7080536 0.319 lysophosphatidylcholine acyltransferase 2 measurement (EFO:0801775)
 PMID:34648354
GWAS621586_H GCST90249643 Sprouty-related, EVH1 domain-containing protein 1 levels 10,708 European ancestry individuals A 0.04 2E-21 20.699 rs7080536 0.321 sprouty-related, EVH1 domain-containing protein 1 measurement (EFO:0803102)
 PMID:34648354
GWAS655697_H GCST008309 Cardiac troponin-I levels 14,579 European ancestry individuals A NR 8E-8 7.097 rs7080536 0.11 cardiac troponin I measurement (EFO:0010071)
 PMID:31014085
GWAS663949_H GCST006417 Plasma factor VII activating protease levels 3,126 Swedish ancestry individuals ? NR 7E-142 141.155 rs7080536 429.0 factor VII activating protease measurement (EFO:0009368)
 PMID:30070759
GWAS702099_H GCST90002381 Eosinophil counts 408,112 British individuals A 0.043284 3E-18 17.523 rs7080536 0.04798498 eosinophil count (EFO:0004842)
 PMID:32888494
GWAS705791_H GCST90002302 Eosinophil counts 583,850 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals A 0.0413959 6E-16 15.222 rs7080536 N/A eosinophil count (EFO:0004842)
 PMID:32888493
GWAS760296_H GCST007065 Eosinophil counts approximately 440,000 European ancestry individuals ? NR 2E-18 17.699 rs7080536 N/A eosinophil count (EFO:0004842)
 PMID:30595370
GWAS763065_H GCST011427 Protein quantitative trait loci (liver) 172 European ancestry individuals, 29 Black individuals, 86 individuals A 0.03136 4E-10 9.398 rs7080536 0.02947 protein measurement (EFO:0004747)
 PMID:32778093
GWAS848555_H GCST90089217 Serum levels of protein IFNGR1 5,366 Icelandic ancestry individuals A 0.03907 4E-31 30.398 rs7080536 0.543041 interferon gamma receptor 1 measurement (EFO:0020484)
 PMID:35078996
GWAS848857_H GCST90090101 Serum levels of protein CLEC5A 5,365 Icelandic ancestry individuals A 0.03907 5E-86 85.302 rs7080536 0.918382 blood protein measurement (EFO:0007937)
 PMID:35078996
GWAS863940_H GCST90087144 Serum levels of protein PACSIN1 5,357 Icelandic ancestry individuals A 0.03907 5E-74 73.302 rs7080536 0.84961 blood protein measurement (EFO:0007937)
 PMID:35078996
GWAS864821_H GCST90054799 High-sensitivity cardiac troponin I concentration 48,115 European ancestry individuals A 0.0431 1E-12 12 rs7080536 0.1 cardiac troponin I measurement (EFO:0010071)
 PMID:33961016
GWAS982234_H GCST90018953 Eosinophil counts 349,856 European ancestry individuals, 93,063 East Asian ancestry individuals A NR 5E-11 10.302 rs7080536 0.0287 eosinophil count (EFO:0004842)
 PMID:34594039
Database Acc Id Source(s)
GWAS Catalog GCST90002382 GWAS Catalog

RGD Curation Notes
Note Type Note Reference