GWAS596657_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS596657_H (coronary artery disease QTL GWAS596657 (human)) Homo sapiens

Symbol: GWAS596657_H
Name: coronary artery disease QTL GWAS596657 (human)
RGD ID: 406947681
Trait: coronary artery disease
LOD Score: Not Available
P Value: 3.0E-17
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38314,857,887 - 14,857,888RGD_MAPPER_PIPELINEGRCh38
GRCh37314,899,394 - 14,899,395RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1313708FGD5FYVE, RhoGEF and PH domain containing 531481068814934571Human

Position Markers

Peak: (rs35462537)
Human AssemblyChrPosition (strand)Source
GRCh38314,857,887 - 14,857,888RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
406947681GWAS596657_Hcoronary artery disease QTL GWAS596657 (human)3e-17coronary artery disease31485788714857888Human
2316345GLUCO224_HGlucose level QTL 224 (human)1.270.008Glucose level3121543441Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS596657_H GCST010866 Coronary artery disease 25,892 Japanese ancestry cases, 95,342 European ancestry cases, 142,336 Japanese ancestry controls, 385,488 European ancestry controls ? NR 3E-17 16.523 rs35462537 0.0428552 coronary artery disease (EFO:0001645)
 PMID:33020668
None Available GCST90435415 Systolic blood pressure 404,507 European ancestry individuals ? NR 1E-17 17 rs35462537 0.0165588 systolic blood pressure (EFO:0006335)
 PMID:39134668
Database Acc Id Source(s)
GWAS Catalog GCST010866 GWAS Catalog

RGD Curation Notes
Note Type Note Reference