GWAS587983_H QTL Report (Homo sapiens) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
QTL Registration

QTL: GWAS587983_H (eosinophil percentage of leukocytes QTL GWAS587983 (human)) Homo sapiens

Symbol: GWAS587983_H
Name: eosinophil percentage of leukocytes QTL GWAS587983 (human)
RGD ID: 406939007
Trait: eosinophil percentage of leukocytes
Measurement Type: blood eosinophil count to total leukocyte count ratio   (CMO:0000369)    
LOD Score: Not Available
P Value: 6.0E-32
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381688,491,756 - 88,491,757RGD_MAPPER_PIPELINEGRCh38
GRCh371688,558,164 - 88,558,165RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS587983_HHumanblood eosinophil count to total leukocyte count ratio  IAGPrs17175830405850206Based on the EFO term IDGWAS_CATALOGPMID:32888494

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS587983_HHumaneosinophil percentage of leukocytes  IAGPrs17175830405850206 GWAS_CATALOGPMID:32888494
Experimental Data Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1314245ZFPM1zinc finger protein, FOG family member 1168845176988537031Human

Position Markers

Peak: (rs17175830)
Human AssemblyChrPosition (strand)Source
GRCh381688,491,756 - 88,491,757RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407042578GWAS691554_Hplatelet count QTL GWAS691554 (human)1e-50platelet quantity (VT:0003179)platelet count (CMO:0000029)168849175688491757Human
407053185GWAS702161_Heosinophil count QTL GWAS702161 (human)4e-42eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)168849175688491757Human
407109249GWAS758225_Hplatelet count QTL GWAS758225 (human)2e-39platelet quantity (VT:0003179)platelet count (CMO:0000029)168849175688491757Human
407108432GWAS757408_Hplatelet crit QTL GWAS757408 (human)4e-35platelet critplateletcrit (CMO:0001349)168849175688491757Human
407113607GWAS762583_Heosinophil count QTL GWAS762583 (human)9e-37eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)168849175688491757Human
406939544GWAS588520_Heosinophil count QTL GWAS588520 (human)2e-37eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)168849175688491757Human
407059433GWAS708409_Heosinophil count QTL GWAS708409 (human)8e-44eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)168849175688491757Human
407042492GWAS691468_Hplatelet count QTL GWAS691468 (human)3e-53platelet quantity (VT:0003179)platelet count (CMO:0000029)168849175688491757Human
406939007GWAS587983_Heosinophil percentage of leukocytes QTL GWAS587983 (human)6e-32eosinophil percentage of leukocytesblood eosinophil count to total leukocyte count ratio (CMO:0000369)168849175688491757Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS587983_H GCST90002382 Eosinophil percentage of white cells 408,112 British individuals A 0.236927 6E-32 31.222 rs17175830 0.03091325 eosinophil percentage of leukocytes (EFO:0007991)
 PMID:32888494
GWAS588520_H GCST90002381 Eosinophil counts 408,112 British individuals A 0.236932 2E-37 36.699 rs17175830 0.03360936 eosinophil count (EFO:0004842)
 PMID:32888494
GWAS691468_H GCST90002361 Platelet count 721,201 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals A 0.266353 3E-53 52.523 rs17175830 N/A platelet count (EFO:0004309)
 PMID:32888493
GWAS691554_H GCST90002357 Platelet count 542,827 European ancestry individuals A 0.238143 1E-50 50 rs17175830 0.034345 platelet count (EFO:0004309)
 PMID:32888493
GWAS702161_H GCST90002298 Eosinophil counts 474,237 European ancestry individuals A 0.237656 4E-42 41.398 rs17175830 0.032179 eosinophil count (EFO:0004842)
 PMID:32888493
GWAS708409_H GCST90002302 Eosinophil counts 583,850 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals A 0.256732 8E-44 43.097 rs17175830 N/A eosinophil count (EFO:0004842)
 PMID:32888493
GWAS757408_H GCST90002400 Plateletcrit 408,112 British individuals A 0.237151 4E-35 34.398 rs17175830 0.033496823 platelet crit (EFO:0007985)
 PMID:32888494
GWAS758225_H GCST90002402 Platelet count 408,112 British individuals A 0.23714 2E-39 38.699 rs17175830 0.035396542 platelet count (EFO:0004309)
 PMID:32888494
GWAS762583_H GCST007065 Eosinophil counts approximately 440,000 European ancestry individuals ? NR 9E-37 36.046 rs17175830 N/A eosinophil count (EFO:0004842)
 PMID:30595370
Database Acc Id Source(s)
GWAS Catalog GCST90002382 GWAS Catalog

RGD Curation Notes
Note Type Note Reference