GWAS585547_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS585547_H (free cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS585547 (human)) Homo sapiens

Symbol: GWAS585547_H
Name: free cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS585547 (human)
RGD ID: 406936571
Trait: free cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement
Measurement Type: blood high density lipoprotein cholesterol level   (CMO:0000052)    
LOD Score: Not Available
P Value: 3.0E-8
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38632,626,607 - 32,626,608RGD_MAPPER_PIPELINEGRCh38
GRCh37632,594,384 - 32,594,385RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS585547_HHumanblood high density lipoprotein cholesterol level  IAGPrs114741460405850206Based on the EFO term IDGWAS_CATALOGPMID:35213538

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS585547_HHumanfree cholesterol:total lipids ratio  IAGPrs114741460405850206 GWAS_CATALOGPMID:35213538
GWAS585547_HHumanhigh density lipoprotein cholesterol measurement  IAGPrs114741460405850206 GWAS_CATALOGPMID:35213538
Experimental Data Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Position Markers

Peak: (rs114741460)
Human AssemblyChrPosition (strand)Source
GRCh38632,626,607 - 32,626,608RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358839MULTSCL5_HMultiple sclerosis susceptibility QTL 5 (human)Multiple sclerosis susceptibility61958431145584311Human
1643377BW325_HBody weight QTL 325 (human)2.320.0005Body fat amount6691196032911960Human
1643569GLUCO21_HGlucose level QTL 21 (human)0.021Glucose levelnon-insulin-dependent6691196032911960Human
1298458BW9_HBody weight QTL 9 (human)2.70.0002Body fat amount6691196032911960Human
406935528GWAS584504_Hcholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement QTL GWAS584504 (human)6e-14cholesteryl esters:total lipids ratio, intermediate density lipoprotein measurementblood intermediate density lipoprotein cholesterol level (CMO:0001562)63262660732626608Human
1298431RA11_HRheumatoid arthritis QTL 11 (human)0.0000024Joint/bone inflammationrheumatoid arthritis61991188340191709Human
407084397GWAS733373_Hphospholipids:total lipids ratio QTL GWAS733373 (human)1e-11phospholipids:total lipids ratio63262660732626608Human
406936783GWAS585759_Hcholesterol:total lipids ratio, intermediate density lipoprotein measurement QTL GWAS585759 (human)1e-14cholesterol:total lipids ratio, intermediate density lipoprotein measurementblood intermediate density lipoprotein cholesterol level (CMO:0001562)63262660732626608Human
406938129GWAS587105_Hcholesterol:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS587105 (human)4e-13cholesterol:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)63262660732626608Human
1358854MULTSCL4_HMultiple sclerosis susceptibility QTL 4 (human)Multiple sclerosis susceptibility6691196032911960Human
406936500GWAS585476_Hphospholipids:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS585476 (human)2e-13phospholipids:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)63262660732626608Human
406936571GWAS585547_Hfree cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS585547 (human)3e-08free cholesterol:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)63262660732626608Human
1358857MULTSCL19_HMultiple sclerosis susceptibility QTL 19 (human)Multiple sclerosis susceptibility61958431145584311Human
1643399BMD5_HBone mineral density QTL 5 (human)2.320.0005Bone mineral density6691196032911960Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS584504_H GCST90092834 Cholesteryl esters to total lipids ratio in IDL 115,082 European ancestry individuals C 0.953428 6E-14 13.222 rs114741460 0.0768716 cholesteryl esters:total lipids ratio (EFO:0020944)
intermediate density lipoprotein measurement (EFO:0008595)
 PMID:35213538
GWAS585476_H GCST90092901 Phospholipids to total lipids ratio in medium HDL 115,082 European ancestry individuals C 0.953428 2E-13 12.699 rs114741460 0.0731865 phospholipids:total lipids ratio (EFO:0020946)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS585547_H GCST90092897 Free cholesterol to total lipids ratio in medium HDL 115,082 European ancestry individuals C 0.953428 3E-8 7.523 rs114741460 0.051812 free cholesterol:total lipids ratio (EFO:0020945)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS585759_H GCST90092832 Cholesterol to total lipids ratio in IDL 115,082 European ancestry individuals C 0.953428 1E-14 14 rs114741460 0.078791 cholesterol:total lipids ratio (EFO:0020943)
intermediate density lipoprotein measurement (EFO:0008595)
 PMID:35213538
GWAS587105_H GCST90092893 Cholesterol to total lipids ratio in medium HDL 115,082 European ancestry individuals C 0.953428 4E-13 12.398 rs114741460 0.0724454 cholesterol:total lipids ratio (EFO:0020943)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS733373_H GCST90269736 Phospholipids to total lipids in medium HDL percentage (UKB data field 23639) 88,329 European ancestry individuals T 0.0466538 1E-11 11 rs114741460 0.0783415 phospholipids:total lipids ratio (EFO:0020946)
 PMID:36764567
Database Acc Id Source(s)
GWAS Catalog GCST90092897 GWAS Catalog

RGD Curation Notes
Note Type Note Reference