GWAS583834_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS583834_H (neuroticism measurement QTL GWAS583834 (human)) Homo sapiens

Symbol: GWAS583834_H
Name: neuroticism measurement QTL GWAS583834 (human)
RGD ID: 406934858
Trait: neuroticism measurement
LOD Score: Not Available
P Value: 1.0E-8
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38352,512,804 - 52,512,805RGD_MAPPER_PIPELINEGRCh38
GRCh37352,546,820 - 52,546,821RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS583834_HHumanneuroticism measurement  IAGPrs2015971405850206 GWAS_CATALOGPMID:29942085
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1321166STAB1stabilin 135249533852524495Human

Position Markers

Peak: (rs2015971)
Human AssemblyChrPosition (strand)Source
GRCh38352,512,804 - 52,512,805RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
406987843GWAS636819_Hneuroticism measurement QTL GWAS636819 (human)2e-10neuroticism measurement35251280452512805Human
1298487BFD1_HBody fluid distribution QTL 1 (human)3.94Body fluid distributionimpedance ratio33638071262380712Human
406990694GWAS639670_Hdepressive symptom measurement QTL GWAS639670 (human)3e-10wellbeing measurement35251280452512805Human
407099876GWAS748852_Hneuroticism measurement QTL GWAS748852 (human)2e-08neuroticism measurement35251280452512805Human
407281793GWAS930769_Hmemory performance QTL GWAS930769 (human)0.000001memory performance35251280452512805Human
1298489RA4_HRheumatoid arthritis QTL 4 (human)0.0283Joint/bone inflammationrheumatoid arthritis33638071262380712Human
406934858GWAS583834_Hneuroticism measurement QTL GWAS583834 (human)1e-08neuroticism measurement35251280452512805Human
1643509BW293_HBody Weight QTL 293 (human)1.42Body weightBMI33638071262380712Human
1331643COPD16_HChronic obstructive pulmonary disease QTL 16 (human)1.07Chronic airflow obstructionpost-BD FEV1 minus pre-BD FEV1/pre-BD FEV1 x 10034938065175380651Human
407284080GWAS933056_Hmemory performance QTL GWAS933056 (human)5e-10memory performance35251280452512805Human
407173715GWAS822691_Hblood protein measurement QTL GWAS822691 (human)2e-12blood protein measurementblood protein measurement (CMO:0000028)35251280452512805Human
406988571GWAS637547_Hwellbeing measurement QTL GWAS637547 (human)1e-09wellbeing measurement35251280452512805Human
2289308BW392_HBody weight QTL 392 (human)1.42Body weightBMI33638071262380712Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS583834_H GCST006476 Neuroticism 449,484 European ancestry individuals T NR 1E-8 8 rs2015971 5.704 neuroticism measurement (EFO:0007660)
 PMID:29942085
GWAS636819_H GCST007339 Neuroticism 523,783 European ancestry individuals T 0.448578302436026 2E-10 9.699 rs2015971 0.0093031665 neuroticism measurement (EFO:0007660)
 PMID:30643256
GWAS637547_H GCST007337 Life satisfaction 80,852 European ancestry individuals T 0.448578302436026 1E-9 9 rs2015971 0.0075768563 wellbeing measurement (EFO:0007869)
 PMID:30643256
GWAS639670_H GCST007340 Depressive symptoms 1,067,913 European ancestry individuals T 0.448578302436026 3E-10 9.523 rs2015971 0.0059366147 depressive symptom measurement (EFO:0007006)
 PMID:30643256
None Available GCST007338 Positive affect 410,603 European ancestry individuals T 0.448578302436026 3E-10 9.523 rs2015971 0.0071475133 wellbeing measurement (EFO:0007869)
 PMID:30643256
GWAS748852_H GCST007084 Neuroticism approximately 372,000 European ancestry individuals ? NR 2E-8 7.699 rs2015971 N/A neuroticism measurement (EFO:0007660)
 PMID:30595370
GWAS822691_H GCST90090340 Serum levels of protein SUN3 5,364 Icelandic ancestry individuals T 0.4871 2E-12 11.699 rs2015971 0.135036 blood protein measurement (EFO:0007937)
 PMID:35078996
GWAS930769_H GCST90162636 Verbal learning (visual presentation) 16,191 European ancestry individuals T 0.3824 0.000001 6 rs2015971 4.841 memory performance (EFO:0004874)
 PMID:35974141
GWAS933056_H GCST90162632 Verbal learning 28,909 European ancestry individuals T 0.3824 5E-10 9.302 rs2015971 6.224 memory performance (EFO:0004874)
 PMID:35974141
Database Acc Id Source(s)
GWAS Catalog GCST006476 GWAS Catalog

RGD Curation Notes
Note Type Note Reference