GWAS572173_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS572173_H (apolipoprotein B measurement QTL GWAS572173 (human)) Homo sapiens

Symbol: GWAS572173_H
Name: apolipoprotein B measurement QTL GWAS572173 (human)
RGD ID: 406923197
Trait: apolipoprotein B measurement
Measurement Type: blood apoliprotein B level   (CMO:0000522)    
LOD Score: Not Available
P Value: 2.0E-13
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh386160,157,037 - 160,157,038RGD_MAPPER_PIPELINEGRCh38
GRCh376160,578,069 - 160,578,070RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS572173_HHumanblood apoliprotein B level  IAGPrs146534110405850206Based on the EFO term IDGWAS_CATALOGPMID:32203549

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS572173_HHumanapolipoprotein B measurement  IAGPrs146534110405850206 GWAS_CATALOGPMID:32203549
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
732626SLC22A1solute carrier family 22 member 16160121815160158718Human

Position Markers

Peak: (rs146534110)
Human AssemblyChrPosition (strand)Source
GRCh386160,157,037 - 160,157,038RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407077696GWAS726672_Htriglycerides to total lipids in chylomicrons and extremely large VLDL percentage QTL GWAS726672 (human)5e-11triglycerides to total lipids in chylomicrons and extremely large VLDL percentage 6160157037160157038Human
407340356GWAS989332_Hlow density lipoprotein cholesterol measurement QTL GWAS989332 (human)1e-18low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)6160157037160157038Human
407296514GWAS945490_Htotal cholesterol measurement QTL GWAS945490 (human)1e-16total cholesterol measurementblood total cholesterol level (CMO:0000051)6160157037160157038Human
407038535GWAS687511_Htriglycerides in chylomicrons and extremely large VLDL measurement QTL GWAS687511 (human)2e-12triglycerides in chylomicrons and extremely large VLDL measurement 6160157037160157038Human
407237760GWAS886736_Hapolipoprotein B measurement QTL GWAS886736 (human)2e-15apolipoprotein B measurementblood apoliprotein B level (CMO:0000522)6160157037160157038Human
407096971GWAS745947_Hcholesteryl esters to total lipids in large VLDL percentage QTL GWAS745947 (human)1e-10cholesteryl esters to total lipids in large VLDL percentage 6160157037160157038Human
407024203GWAS673179_Hcholesterol to total lipids in large VLDL percentage QTL GWAS673179 (human)7e-10cholesterol to total lipids in large VLDL percentage 6160157037160157038Human
407023983GWAS672959_Hcholesteryl esters to total lipids in very large VLDL percentage QTL GWAS672959 (human)5e-10cholesteryl esters to total lipids in very large VLDL percentage 6160157037160157038Human
407074606GWAS723582_Hcholesterol to total lipids in chylomicrons and extremely large VLDL percentage QTL GWAS723582 (human)6e-13cholesterol to total lipids in chylomicrons and extremely large VLDL percentage 6160157037160157038Human
406918578GWAS567554_Hlow density lipoprotein cholesterol measurement QTL GWAS567554 (human)9e-14low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)6160157037160157038Human
1643404BMD3_HBone mineral density QTL 3 (human)2.420.0005Bone mineral density6157563614170805979Human
407310290GWAS959266_Hlipoprotein A measurement QTL GWAS959266 (human)2e-285lipoprotein A measurement6160157037160157038Human
407038394GWAS687370_Htotal lipids in chylomicrons and extremely large VLDL measurement QTL GWAS687370 (human)3e-10total lipids in chylomicrons and extremely large VLDL measurement 6160157037160157038Human
406923197GWAS572173_Hapolipoprotein B measurement QTL GWAS572173 (human)2e-13apolipoprotein B measurementblood apoliprotein B level (CMO:0000522)6160157037160157038Human
407075870GWAS724846_Hcholesteryl esters to total lipids in chylomicrons and extremely large VLDL percentage QTL GWAS724846 (human)7e-12cholesteryl esters to total lipids in chylomicrons and extremely large VLDL percentage 6160157037160157038Human
1643367BW323_HBody weight QTL 323 (human)2.420.0005Body fat amount6157563614170805979Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS567554_H GCST010245 LDL cholesterol levels 440,546 European ancestry individuals G 0.986696 9E-14 13.046 rs146534110 0.0679152 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:32203549
GWAS572173_H GCST010243 Apolipoprotein B levels 439,214 European ancestry individuals G 0.986685 2E-13 12.699 rs146534110 0.0666046 apolipoprotein B measurement (EFO:0004615)
 PMID:32203549
GWAS672959_H GCST90269683 Cholesteryl esters to total lipids in very large VLDL percentage (UKB data field 23586) 87,620 European ancestry individuals T 0.0135643 5E-10 9.302 rs146534110 0.122644 cholesteryl esters to total lipids in very large VLDL percentage (EFO:0022258)
 PMID:36764567
GWAS673179_H GCST90269687 Cholesterol to total lipids in large VLDL percentage (UKB data field 23590) 88,321 European ancestry individuals T 0.0136547 7E-10 9.155 rs146534110 0.123412 cholesterol to total lipids in large VLDL percentage (EFO:0022236)
 PMID:36764567
GWAS687370_H GCST90269579 Total lipids in chylomicrons and extremely large VLDL (UKB data field 23482) 88,329 European ancestry individuals T 0.0136535 3E-10 9.523 rs146534110 0.124655 total lipids in chylomicrons and extremely large VLDL measurement (EFO:0022306)
 PMID:36764567
GWAS687511_H GCST90269584 Triglycerides in chylomicrons and extremely large VLDL (UKB data field 23487) 88,329 European ancestry individuals T 0.0136535 2E-12 11.699 rs146534110 0.138363 triglycerides in chylomicrons and extremely large VLDL measurement (EFO:0022316)
 PMID:36764567
GWAS723582_H GCST90269677 Cholesterol to total lipids in chylomicrons and extremely large VLDL percentage (UKB data field 23580) 85,701 European ancestry individuals T 0.0134888 6E-13 12.222 rs146534110 0.148371 cholesterol to total lipids in chylomicrons and extremely large VLDL percentage (EFO:0022232)
 PMID:36764567
GWAS724846_H GCST90269678 Cholesteryl esters to total lipids in chylomicrons and extremely large VLDL percentage (UKB data field 23581) 85,701 European ancestry individuals T 0.0134888 7E-12 11.155 rs146534110 0.142048 cholesteryl esters to total lipids in chylomicrons and extremely large VLDL percentage (EFO:0022246)
 PMID:36764567
GWAS726672_H GCST90269680 Triglycerides to total lipids in chylomicrons and extremely large VLDL percentage (UKB data field 23583) 85,701 European ancestry individuals T 0.0134888 5E-11 10.302 rs146534110 0.1363 triglycerides to total lipids in chylomicrons and extremely large VLDL percentage (EFO:0022328)
 PMID:36764567
GWAS745947_H GCST90269688 Cholesteryl esters to total lipids in large VLDL percentage (UKB data field 23591) 88,321 European ancestry individuals T 0.0136547 1E-10 10 rs146534110 0.126389 cholesteryl esters to total lipids in large VLDL percentage (EFO:0022250)
 PMID:36764567
GWAS886736_H GCST90019496 Apolipoprotein B levels 340,860 European ancestry individuals, 5,962 African ancestry individuals, 7,275 South Asian ancestry individuals T NR 2E-15 14.699 rs146534110 0.0829 apolipoprotein B measurement (EFO:0004615)
 PMID:33462484
GWAS945490_H GCST90019501 Total cholesterol levels 342,508 European ancestry individuals, 6,014 African ancestry individuals, 7,336 South Asian ancestry individuals T NR 1E-16 16 rs146534110 0.0867 total cholesterol measurement (EFO:0004574)
 PMID:33462484
GWAS959266_H GCST90019513 Lipoprotein (a) levels 272,573 European ancestry individuals, 5,018 African ancestry individuals, 6,453 South Asian ancestry individuals T NR 2E-285 284.699 rs146534110 0.4336 lipoprotein A measurement (EFO:0006925)
 PMID:33462484
GWAS989332_H GCST90019512 Low density lipoprotein cholesterol levels 341,875 European ancestry individuals, 6,003 African ancestry individuals, 7,319 South Asian ancestry individuals T NR 1E-18 18 rs146534110 0.0922 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:33462484
Database Acc Id Source(s)
GWAS Catalog GCST010243 GWAS Catalog

RGD Curation Notes
Note Type Note Reference