Ean1 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Ean1 (Experimental allergic neuritis QTL 1) Rattus norvegicus

Symbol: Ean1
Name: Experimental allergic neuritis QTL 1
RGD ID: 2306790
Trait: nervous system integrity trait   (VT:0010566)    
Measurement Type: experimental autoimmune neuritis severity score   (CMO:0001528)    
LOD Score: Not Available
P Value: 0.05
Variance: Not Available
Position No map positions available.
Cross Type: intercross
Strains Crossed: LEW.1AV1 



Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain
LEW.1AV1  (IEA)

References

References - curated
# Reference Title Reference Citation
1. MHC and non-MHC gene regulation of disease susceptibility and disease course in experimental inflammatory peripheral neuropathy. de Graaf KL, etal., J Neuroimmunol. 2004 Oct;155(1-2):73-84.

Region

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch

Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_cross_type intercross  
qtl_general number of animals used: 41 males 14-20 weeks old 2306736
qtl_general inducing agent: bPNM (bovine peripheral nerve myelin) or P2 58-81 2306736
qtl_general measurement method: rats were anesthetized with methoxyflurane then 2mg bPNM (bovine peripheral nerve myelin) in saline or P2 58-81 in saline was injected at the base of the tail then scored: grade 1, tail weakness or paralysis; grade 2, gait ataxia hind leg paraparesis; grade 3, hind leg paralysis; grade 4, complete paralysis 2306736
qtl_general software used: ANOVA 2306736
qtl_general MHC class II genes are major susceptibility genes 2306736