OSTEAR19_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: OSTEAR19_H (Osteoarthritis QTL 19 (human)) Homo sapiens

Symbol: OSTEAR19_H
Name: Osteoarthritis QTL 19 (human)
RGD ID: 1298405
Previously known as: OA19_H
Trait: Joint/bone inflammation
Measurement Type: ideopathic hand osteoarthritis
LOD Score: Not Available
P Value: 1.79
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37371,223,818 - 78,871,336RGDGRCh37
Build 36371,306,508 - 78,954,026RGDNCBI36
Build 34371,206,508 - 79,054,077RGD
Cross Type: Not Available
Population Stats: Icelandic patients diagnosed with ideopathic hand osteoarthritis



Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
Arthritis  (QTM)
References

References - curated
# Reference Title Reference Citation
1. Genomewide scan for hand osteoarthritis: a novel mutation in matrilin-3. Stefansson SE, etal., Am J Hum Genet 2003 Jun;72(6):1448-59. Epub 2003 May 7.

Region

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
Position Markers

Flank 1: (D3S1562)
Human AssemblyChrPosition (strand)Source
GRCh37371,223,818 - 71,223,995UniSTS
GRCh37371,223,896 - 71,224,056UniSTS
Build 36371,306,508 - 71,306,685RGD
Celera371,150,769 - 71,150,954RGD
Celera371,150,847 - 71,151,015UniSTS
Cytogenetic Map3p14.1UniSTS
HuRef371,222,714 - 71,222,874UniSTS
HuRef371,222,636 - 71,222,813UniSTS
Marshfield Genetic Map397.75RGD
Genethon Genetic Map397.2UniSTS
TNG Radiation Hybrid Map322930.0UniSTS
deCODE Assembly Map396.05UniSTS
Whitehead-YAC Contig Map3 UniSTS
Peak: (D3S3551)
Human AssemblyChrPosition (strand)Source
GRCh37371,778,889 - 71,779,138UniSTS
Build 36371,861,579 - 71,861,828RGD
Celera371,709,479 - 71,709,732RGD
Cytogenetic Map3p14UniSTS
HuRef371,781,003 - 71,781,256UniSTS
Marshfield Genetic Map399.38RGD
Marshfield Genetic Map399.38UniSTS
Genethon Genetic Map398.8UniSTS
TNG Radiation Hybrid Map346474.0UniSTS
deCODE Assembly Map396.78UniSTS
Whitehead-YAC Contig Map3 UniSTS
Flank 2: (D3S1274)
Human AssemblyChrPosition (strand)Source
GRCh37378,871,209 - 78,871,336UniSTS
Build 36378,953,899 - 78,954,026RGD
Celera379,615,103 - 79,615,230RGD
Cytogenetic Map3p12UniSTS
HuRef378,890,738 - 78,890,865UniSTS
Marshfield Genetic Map3109.22RGD
Marshfield Genetic Map3109.22UniSTS
Genethon Genetic Map3108.8UniSTS
deCODE Assembly Map3107.18UniSTS
Whitehead-YAC Contig Map3 UniSTS


Additional Information

Database Acc Id Source(s)
NCBI Gene OSTEAR19_H
OMIM 607850


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-04-14 OSTEAR19_H  Osteoarthritis QTL 19 (human)  OA19_H    Symbol updated 1299863 APPROVED

RGD Curation Notes
Note Type Note Reference
qtl_population Icelandic patients diagnosed with ideopathic hand osteoarthritis 738123
qtl_population_details study included 1143 affected individuals, 939 of their unaffected relatives, and 873 unrelated control individuals 738123
qtl_statistics_details multipoint and nonparametric linkage scores were generated with the ALLEGRO program 738123
qtl_statistics_details LOD score was unchanged when analyed for distal interphalangeal or first carpometacarpal subphenotype 738123