Pnck (pregnancy up-regulated nonubiquitous CaM kinase) - Rat Genome Database

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Gene: Pnck (pregnancy up-regulated nonubiquitous CaM kinase) Rattus norvegicus
Analyze
Symbol: Pnck
Name: pregnancy up-regulated nonubiquitous CaM kinase
RGD ID: 69249
Description: Enables calcium/calmodulin-dependent protein kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. Predicted to be active in cytoplasm. Orthologous to human PNCK (pregnancy up-regulated nonubiquitous CaM kinase); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: calcium/calmodulin-dependent protein kinase 1 beta; calcium/calmodulin-dependent protein kinase 1, beta; calcium/calmodulin-dependent protein kinase type 1B; caM kinase I beta; caM kinase IB; caM-KI beta; Camk1b; caMKI-beta; LOC100360379; pregnancy up-regulated non-ubiquitously-expressed CaM kinase homolog; pregnancy upregulated non-ubiquitously expressed CaM kinase; Protein Kinase-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X156,520,751 - 156,524,828 (-)NCBIGRCr8
mRatBN7.2X151,369,406 - 151,373,508 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX151,369,410 - 151,373,446 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX153,510,581 - 153,514,481 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X157,073,812 - 157,077,712 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X154,745,644 - 154,749,544 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X157,150,071 - 157,154,558 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX157,150,655 - 157,154,555 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01152,900,009 - 152,904,076 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X45,741,127 - 45,741,920 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X159,628,959 - 159,632,860 (-)NCBI
Celera1136,516,497 - 136,520,397 (+)NCBICelera
Cytogenetic MapXq37NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
PnckRatadrenoleukodystrophy  ISOPNCK (Homo sapiens)8554872ClinVar Annotator: match by term: AdrenoleukodystrophyClinVarPMID:10480214 more ...
PnckRatautistic disorder  ISOPNCK (Homo sapiens)8554872ClinVar Annotator: match by term: AutismClinVarPMID:21681106 and PMID:30208311
PnckRatautosomal hemophilia A  ISOPNCK (Homo sapiens)8554872ClinVar Annotator: match by term: AUTOSOMAL HEMOPHILIA AClinVarPMID:31690835
PnckRatBarth syndrome  ISOPNCK (Homo sapiens)8554872ClinVar Annotator: match by term: 3-Methylglutaconic aciduria type 2ClinVarPMID:10480214 more ...
PnckRatcerebral creatine deficiency syndrome 1  ISOPNCK (Homo sapiens)8554872ClinVar Annotator: match by term: Creatine transporter deficiencyClinVarPMID:10480214 more ...
PnckRatChromosome Xq28 Duplication Syndrome  ISOPNCK (Homo sapiens)8554872ClinVar Annotator: match by term: Chromosome Xq28 duplication syndromeClinVar 
PnckRatdyskeratosis congenita  ISOPNCK (Homo sapiens)8554872ClinVar Annotator: match by term: Dyskeratosis congenitaClinVarPMID:18177777 and PMID:28492532
PnckRatEmery-Dreifuss muscular dystrophy  ISOPNCK (Homo sapiens)8554872ClinVar Annotator: match by term: X-linked Emery-Dreifuss muscular dystrophyClinVarPMID:10480214 more ...
PnckRatfactor VIII deficiency  ISOPNCK (Homo sapiens)8554872ClinVar Annotator: match by term: Factor 8 deficiency and congenitalClinVarPMID:31690835
PnckRatfavism  ISOPNCK (Homo sapiens)8554872ClinVar Annotator: match by term: Anemia more ...ClinVarPMID:18177777 and PMID:28492532
PnckRatimmunodeficiency 33  ISOPNCK (Homo sapiens)8554872ClinVar Annotator: match by term: Immunodeficiency 33ClinVarPMID:25741868
PnckRatparaplegia  ISOPNCK (Homo sapiens)8554872ClinVar Annotator: match by term: Spastic paraplegiaClinVarPMID:10480214 more ...
PnckRatperiventricular nodular heterotopia  ISOPNCK (Homo sapiens)8554872ClinVar Annotator: match by term: Heterotopia more ...ClinVarPMID:10480214 more ...
PnckRatsevere congenital encephalopathy due to MECP2 mutation  ISOPNCK (Homo sapiens)8554872ClinVar Annotator: match by term: Severe neonatal-onset encephalopathy with microcephalyClinVarPMID:12180070 more ...
PnckRatSplenomegaly  ISOPNCK (Homo sapiens)8554872ClinVar Annotator: match by term: SplenomegalyClinVarPMID:25741868
PnckRatsyndromic X-linked intellectual disability Lubs type  ISOPNCK (Homo sapiens)8554872ClinVar Annotator: match by term: Syndromic X-linked intellectual disability Lubs typeClinVarPMID:22679399 more ...
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1 to 20 of 58 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
PnckRat1,2-dimethylhydrazine increases expressionISOPnck (Mus musculus)64804641 and 2-Dimethylhydrazine results in increased expression of PNCK mRNACTDPMID:22206623
PnckRat2,2',4,4',5,5'-hexachlorobiphenyl multiple interactionsISOPnck (Mus musculus)6480464[2 more ...CTDPMID:25510870
PnckRat2,2',5,5'-tetrachlorobiphenyl multiple interactionsISOPnck (Mus musculus)6480464[2 more ...CTDPMID:25510870
PnckRat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOPNCK (Homo sapiens)6480464PNCK mRNA affects the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]CTDPMID:21479225
PnckRat4-hydroxyphenyl retinamide increases expressionISOPnck (Mus musculus)6480464Fenretinide results in increased expression of PNCK mRNACTDPMID:28973697
PnckRat5-aza-2'-deoxycytidine affects expressionISOPNCK (Homo sapiens)6480464Decitabine affects the expression of PNCK mRNACTDPMID:23300844
PnckRat6-propyl-2-thiouracil increases expressionEXP 6480464Propylthiouracil results in increased expression of PNCK mRNACTDPMID:24780913
PnckRatacrylamide decreases expressionISOPNCK (Homo sapiens)6480464Acrylamide results in decreased expression of PNCK mRNACTDPMID:32763439
PnckRatactinomycin D multiple interactionsISOPNCK (Homo sapiens)6480464[Dactinomycin co-treated with nutlin 3] results in increased expression of PNCK mRNACTDPMID:38460933
PnckRataflatoxin B1 increases methylationISOPNCK (Homo sapiens)6480464Aflatoxin B1 results in increased methylation of PNCK exonCTDPMID:30157460
PnckRatAflatoxin B2 alpha increases methylationISOPNCK (Homo sapiens)6480464aflatoxin B2 results in increased methylation of PNCK exonCTDPMID:30157460
PnckRatamitrole increases expressionEXP 6480464Amitrole results in increased expression of PNCK mRNACTDPMID:38685447
PnckRatarsenite(3-) increases expressionISOPnck (Mus musculus)6480464arsenite results in increased expression of PNCK mRNACTDPMID:33053406
PnckRatbenzo[a]pyrene multiple interactionsISOPnck (Mus musculus)6480464Benzo(a)pyrene promotes the reaction [AHR protein binds to PNCK promoter]CTDPMID:19654925
PnckRatbenzo[a]pyrene decreases methylationISOPNCK (Homo sapiens)6480464Benzo(a)pyrene results in decreased methylation of PNCK 3' UTR and Benzo(a)pyrene results in decreased methylation of PNCK promoterCTDPMID:27901495
PnckRatbenzo[a]pyrene increases methylationISOPNCK (Homo sapiens)6480464Benzo(a)pyrene results in increased methylation of PNCK exonCTDPMID:27901495
PnckRatbenzo[a]pyrene increases expressionISOPnck (Mus musculus)6480464Benzo(a)pyrene results in increased expression of PNCK mRNACTDPMID:22228805
PnckRatbis(2-ethylhexyl) phthalate decreases expressionISOPNCK (Homo sapiens)6480464Diethylhexyl Phthalate results in decreased expression of PNCK mRNACTDPMID:31163220
PnckRatbisphenol A decreases expressionEXP 6480464bisphenol A results in decreased expression of PNCK mRNACTDPMID:25181051 and PMID:34947998
PnckRatbisphenol A affects expressionISOPNCK (Homo sapiens)6480464bisphenol A affects the expression of PNCK mRNACTDPMID:30903817

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Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
PnckRatsignal transduction involved_inIBAMGI:1098535 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
PnckRatcytoplasm is_active_inIBACGD:CAL0000193471 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
PnckRatnucleus located_inIEAUniProtKB-SubCell:SL-01911600115GO_REF:0000044UniProtGO_REF:0000044

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
PnckRatATP binding enablesIEAUniProtKB-KW:KW-00671600115GO_REF:0000043UniProtGO_REF:0000043
PnckRatcalcium/calmodulin-dependent protein kinase activity  IDA 68883 RGD 
PnckRatcalcium/calmodulin-dependent protein kinase activity enablesIBAMGI:2388073 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
PnckRatcalmodulin binding enablesIBAPANTHER:PTN001218105 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
PnckRatprotein serine kinase activity enablesIEARHEA:179891600115GO_REF:0000116RHEAGO_REF:0000116


1 to 9 of 9 rows
#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Isoform-specific activation and structural diversity of calmodulin kinase I. Naito Y, etal., J Biol Chem 1997 Dec 19;272(51):32704-8.
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
8. Differential regulatory mechanism of Ca2+/calmodulin-dependent protein kinase kinase isoforms. Tokumitsu H, etal., Biochemistry 2001 Nov 20;40(46):13925-32.
9. Isolation and comparison of rat cDNAs encoding Ca2+/calmodulin-dependent protein kinase I isoforms. Yokokura H, etal., Biochim Biophys Acta 1997 Mar 7;1338(1):8-12.
1 to 9 of 9 rows
PMID:11264466   PMID:19292454   PMID:22871113  



Pnck
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X156,520,751 - 156,524,828 (-)NCBIGRCr8
mRatBN7.2X151,369,406 - 151,373,508 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX151,369,410 - 151,373,446 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX153,510,581 - 153,514,481 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X157,073,812 - 157,077,712 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X154,745,644 - 154,749,544 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X157,150,071 - 157,154,558 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX157,150,655 - 157,154,555 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01152,900,009 - 152,904,076 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X45,741,127 - 45,741,920 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X159,628,959 - 159,632,860 (-)NCBI
Celera1136,516,497 - 136,520,397 (+)NCBICelera
Cytogenetic MapXq37NCBI
PNCK
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X153,669,733 - 153,687,771 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX153,669,733 - 153,689,010 (-)EnsemblGRCh38hg38GRCh38
GRCh37X152,935,188 - 152,953,226 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X152,588,417 - 152,592,974 (-)NCBINCBI36Build 36hg18NCBI36
CeleraX153,168,872 - 153,173,500 (-)NCBICelera
Cytogenetic MapXq28NCBI
HuRefX141,592,549 - 141,597,177 (-)NCBIHuRef
CHM1_1X152,809,688 - 152,814,316 (-)NCBICHM1_1
T2T-CHM13v2.0X151,943,398 - 151,961,436 (-)NCBIT2T-CHM13v2.0
Pnck
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X72,699,598 - 72,703,723 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX72,699,600 - 72,703,723 (-)EnsemblGRCm39 Ensembl
GRCm38X73,655,992 - 73,660,117 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX73,655,994 - 73,660,117 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X70,901,333 - 70,905,167 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X69,908,714 - 69,912,548 (-)NCBIMGSCv36mm8
CeleraX64,909,809 - 64,913,643 (-)NCBICelera
Cytogenetic MapXA7.3NCBI
cM MapX37.38NCBI
Pnck
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955580401,297 - 405,065 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955580401,411 - 406,663 (-)NCBIChiLan1.0ChiLan1.0
PNCK
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X153,709,882 - 153,714,516 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X153,713,486 - 153,718,120 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X143,220,029 - 143,224,659 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X153,106,491 - 153,123,897 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX153,106,491 - 153,123,897 (-)Ensemblpanpan1.1panPan2
PNCK
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X121,489,041 - 121,491,356 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX121,489,040 - 121,491,431 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX106,819,067 - 106,822,956 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X124,631,200 - 124,635,086 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX124,631,204 - 124,635,176 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X120,400,661 - 120,404,547 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X122,915,659 - 122,919,533 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X122,677,778 - 122,681,665 (-)NCBIUU_Cfam_GSD_1.0
Pnck
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X118,815,663 - 118,819,645 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936809553,431 - 557,427 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936809553,438 - 557,385 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PNCK
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX124,425,872 - 124,429,261 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X124,425,867 - 124,430,000 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X141,989,364 - 141,993,498 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PNCK
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X128,099,736 - 128,104,348 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX128,099,682 - 128,103,121 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606565,961,824 - 65,966,436 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pnck
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624946376,856 - 391,192 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624946377,454 - 391,055 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Pnck
1 total Variants

Predicted Target Of
Summary Value
Count of predictions:343
Count of miRNA genes:218
Interacting mature miRNAs:252
Transcripts:ENSRNOT00000024227
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
634346Insul4Insulin level QTL 40blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)X126975089152453651Rat
10059603Bw174Body weight QTL 1743.40.025body mass (VT:0001259)body weight (CMO:0000012)X113937816152453651Rat

RH137751  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X151,369,452 - 151,369,587 (-)MAPPERmRatBN7.2
Rnor_6.0X157,154,378 - 157,154,512NCBIRnor6.0
Rnor_5.01152,903,895 - 152,904,029UniSTSRnor5.0
RGSC_v3.4X159,555,568 - 159,555,702UniSTSRGSC3.4
Celera1136,520,220 - 136,520,354UniSTS
RH 3.4 Map11646.0UniSTS
Cytogenetic MapXq37UniSTS
UniSTS:546957  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X151,369,441 - 151,370,707 (-)MAPPERmRatBN7.2
Rnor_6.0X157,153,258 - 157,154,523NCBIRnor6.0
Rnor_5.01152,902,775 - 152,904,040UniSTSRnor5.0
Celera1136,519,100 - 136,520,365UniSTS
Cytogenetic MapXq37UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
8 9 40 109 83 79 57 12 57 6 178 71 93 36 55 22



Ensembl Acc Id: ENSRNOT00000090795   ⟹   ENSRNOP00000074179
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX151,369,410 - 151,373,310 (-)Ensembl
Rnor_6.0 EnsemblX157,150,655 - 157,154,555 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000095467   ⟹   ENSRNOP00000094811
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX151,369,410 - 151,373,446 (-)Ensembl
RefSeq Acc Id: NM_017275   ⟹   NP_058971
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X156,520,753 - 156,524,653 (-)NCBI
mRatBN7.2X151,369,410 - 151,373,310 (-)NCBI
Rnor_6.0X157,150,655 - 157,154,555 (+)NCBI
Rnor_5.01152,900,009 - 152,904,076 (+)NCBI
RGSC_v3.4X45,741,127 - 45,741,920 (+)RGD
Celera1136,516,497 - 136,520,397 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006229572   ⟹   XP_006229634
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X156,520,751 - 156,524,760 (-)NCBI
mRatBN7.2X151,369,406 - 151,373,373 (-)NCBI
Rnor_6.0X157,150,604 - 157,154,558 (+)NCBI
Rnor_5.01152,900,009 - 152,904,076 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006229573   ⟹   XP_006229635
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X156,520,751 - 156,524,828 (-)NCBI
mRatBN7.2X151,369,406 - 151,373,508 (-)NCBI
Rnor_6.0X157,150,511 - 157,154,558 (+)NCBI
Rnor_5.01152,900,009 - 152,904,076 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006229575   ⟹   XP_006229637
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X156,520,751 - 156,524,713 (-)NCBI
mRatBN7.2X151,369,406 - 151,373,373 (-)NCBI
Rnor_6.0X157,150,604 - 157,154,558 (+)NCBI
Rnor_5.01152,900,009 - 152,904,076 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008773628   ⟹   XP_008771850
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X156,520,751 - 156,524,298 (-)NCBI
mRatBN7.2X151,369,406 - 151,372,964 (-)NCBI
Rnor_6.0X157,150,944 - 157,154,558 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063279872   ⟹   XP_063135942
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X156,520,751 - 156,524,767 (-)NCBI
RefSeq Acc Id: XM_063279873   ⟹   XP_063135943
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X156,520,751 - 156,524,717 (-)NCBI
RefSeq Acc Id: NP_058971   ⟸   NM_017275
- UniProtKB: O08767 (UniProtKB/Swiss-Prot),   O70150 (UniProtKB/Swiss-Prot),   A6KRX3 (UniProtKB/TrEMBL),   A6KRX2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006229635   ⟸   XM_006229573
- Peptide Label: isoform X2
- UniProtKB: O08767 (UniProtKB/Swiss-Prot),   O70150 (UniProtKB/Swiss-Prot),   A6KRX3 (UniProtKB/TrEMBL),   A6KRX2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006229634   ⟸   XM_006229572
- Peptide Label: isoform X1
- UniProtKB: A6KRX1 (UniProtKB/TrEMBL),   A6KRX2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006229637   ⟸   XM_006229575
- Peptide Label: isoform X2
- UniProtKB: O08767 (UniProtKB/Swiss-Prot),   O70150 (UniProtKB/Swiss-Prot),   A6KRX3 (UniProtKB/TrEMBL),   A6KRX2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008771850   ⟸   XM_008773628
- Peptide Label: isoform X2
- UniProtKB: O08767 (UniProtKB/Swiss-Prot),   O70150 (UniProtKB/Swiss-Prot),   A6KRX3 (UniProtKB/TrEMBL),   A6KRX2 (UniProtKB/TrEMBL)
- Sequence:
Protein kinase

Name Modeler Protein Id AA Range Protein Structure
AF-O70150-F1-model_v2 AlphaFold O70150 1-343 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 30 of 30 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-669 BioCyc
Ensembl Genes ENSRNOG00000058317 Ensembl, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000090795.2 UniProtKB/Swiss-Prot
  ENSRNOT00000095467.1 UniProtKB/Swiss-Prot
Gene3D-CATH Phosphorylase Kinase, domain 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro CaMKI_beta_STKc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:29660 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 29660 ENTREZGENE
PANTHER SERINE/THREONINE-PROTEIN KINASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pnck PhenoGen
PROSITE PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000058317 RatGTEx
SMART S_TKc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Protein kinase-like (PK-like) UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
TIGR TC231859
UniProt A6KRX1 ENTREZGENE, UniProtKB/TrEMBL
  A6KRX2 ENTREZGENE, UniProtKB/TrEMBL
  A6KRX3 ENTREZGENE, UniProtKB/TrEMBL
  KCC1B_RAT UniProtKB/Swiss-Prot
  O08767 ENTREZGENE
  O70150 ENTREZGENE
UniProt Secondary O08767 UniProtKB/Swiss-Prot
1 to 30 of 30 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-11-22 Pnck  pregnancy up-regulated nonubiquitous CaM kinase  Pnck  pregnancy upregulated non-ubiquitously expressed CaM kinase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-04-17 Pnck  pregnancy upregulated non-ubiquitously expressed CaM kinase  LOC100360379  Protein Kinase-like  Data merged from RGD:2322274 737654 PROVISIONAL
2010-05-06 LOC100360379  Protein Kinase-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2003-04-09 Pnck  pregnancy upregulated non-ubiquitously expressed CaM kinase  Camk1b  calcium/calmodulin-dependent protein kinase 1, beta   Symbol and Name updated 629477 APPROVED
2002-06-10 Camk1b  calcium/calmodulin-dependent protein kinase 1, beta       Name updated 70584 APPROVED

Note Type Note Reference
gene_expression alternatively spliced form CaM kiinase Ibeta2 is exprssed in cerebrum and cerebellum; alternatively spliced form CaM kinase IbetaI is expressed in liver, heart, lung, and kidney, spleen, and testis 68883