Gcm1 (glial cells missing transcription factor 1) - Rat Genome Database

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Gene: Gcm1 (glial cells missing transcription factor 1) Rattus norvegicus
Analyze
Symbol: Gcm1
Name: glial cells missing transcription factor 1
RGD ID: 61852
Description: Predicted to enable several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; histone deacetylase binding activity; and zinc ion binding activity. Predicted to be involved in several processes, including cell differentiation involved in embryonic placenta development; regulation of cell differentiation involved in embryonic placenta development; and transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including astrocyte fate commitment; branching involved in labyrinthine layer morphogenesis; and positive regulation of syncytium formation by plasma membrane fusion. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Orthologous to human GCM1 (glial cells missing transcription factor 1); INTERACTS WITH (S)-nicotine; 2,2',4,4'-Tetrabromodiphenyl ether; 3,7-dihydropurine-6-thione.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: chorion-specific transcription factor GCMa; GCM motif protein 1; Gcma; glial cells missing homolog 1; glial cells missing homolog 1 (Drosophila)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8887,805,993 - 87,819,229 (+)NCBIGRCr8
mRatBN7.2878,925,687 - 78,938,924 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl878,925,687 - 78,938,924 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx884,412,841 - 84,426,055 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0882,689,502 - 82,702,716 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0880,512,207 - 80,525,423 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0885,355,766 - 85,369,002 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl885,355,766 - 85,369,002 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0884,920,654 - 84,933,890 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4883,018,975 - 83,032,211 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1883,038,028 - 83,051,265 (+)NCBI
Celera878,670,476 - 78,683,712 (+)NCBICelera
Cytogenetic Map8q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gcm1Rat(25R)-cholest-5-ene-3beta,26-diol decreases expressionISOGcm1 (Mus musculus)648046427-hydroxycholesterol results in decreased expression of GCM1 proteinCTDPMID:38180513
Gcm1Rat(25R)-cholest-5-ene-3beta,26-diol decreases expressionISOGCM1 (Homo sapiens)648046427-hydroxycholesterol results in decreased expression of GCM1 proteinCTDPMID:38180513
Gcm1Rat(25R)-cholest-5-ene-3beta,26-diol multiple interactionsISOGCM1 (Homo sapiens)64804642-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [27-hydroxycholesterol results in decreased expression of GCM1 protein]CTDPMID:38180513
Gcm1Rat(S)-nicotine decreases expressionEXP 6480464Nicotine results in decreased expression of GCM1 mRNA and Nicotine results in decreased expression of GCM1 proteinCTDPMID:24368670
Gcm1Rat2,2',4,4'-Tetrabromodiphenyl ether decreases expressionEXP 64804642 more ...CTDPMID:27291303
Gcm1Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOGcm1 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of GCM1 mRNACTDPMID:24058054
Gcm1Rat26-hydroxycholesterol multiple interactionsISOGCM1 (Homo sapiens)64804642-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [27-hydroxycholesterol results in decreased expression of GCM1 protein]CTDPMID:38180513
Gcm1Rat26-hydroxycholesterol decreases expressionISOGcm1 (Mus musculus)648046427-hydroxycholesterol results in decreased expression of GCM1 proteinCTDPMID:38180513
Gcm1Rat26-hydroxycholesterol decreases expressionISOGCM1 (Homo sapiens)648046427-hydroxycholesterol results in decreased expression of GCM1 proteinCTDPMID:38180513
Gcm1Rat3,7-dihydropurine-6-thione decreases expressionEXP 6480464Mercaptopurine results in decreased expression of GCM1 mRNACTDPMID:23358152
Gcm1Ratacetaldehyde affects expressionISOGcm1 (Mus musculus)6480464Acetaldehyde affects the expression of GCM1 mRNACTDPMID:22634333
Gcm1Ratacetic acid increases expressionISOGcm1 (Mus musculus)6480464Acetic Acid results in increased expression of GCM1 proteinCTDPMID:21296659
Gcm1Ratammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of GCM1 mRNACTDPMID:16483693
Gcm1Ratbenzo[a]pyrene increases methylationISOGCM1 (Homo sapiens)6480464Benzo(a)pyrene results in increased methylation of GCM1 5' UTR and Benzo(a)pyrene results in increased methylation of GCM1 promoterCTDPMID:27901495
Gcm1Ratbenzo[a]pyrene multiple interactionsISOGcm1 (Mus musculus)6480464[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of GCM1 mRNACTDPMID:27858113
Gcm1Ratbenzo[b]fluoranthene multiple interactionsISOGcm1 (Mus musculus)6480464[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of GCM1 mRNACTDPMID:27858113
Gcm1Ratbenzo[e]pyrene decreases methylationISOGCM1 (Homo sapiens)6480464benzo(e)pyrene results in decreased methylation of GCM1 intronCTDPMID:30157460
Gcm1Ratbeta-naphthoflavone decreases expressionISOGCM1 (Homo sapiens)6480464beta-Naphthoflavone results in decreased expression of GCM1 mRNACTDPMID:32858204
Gcm1Ratbis(2-chloroethyl) sulfide increases expressionISOGcm1 (Mus musculus)6480464Mustard Gas results in increased expression of GCM1 mRNACTDPMID:15674843
Gcm1Ratbis(2-ethylhexyl) phthalate decreases expressionISOGcm1 (Mus musculus)6480464Diethylhexyl Phthalate results in decreased expression of GCM1 mRNACTDPMID:34319233

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Biological Process
1 to 20 of 28 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gcm1Ratastrocyte fate commitment acts_upstream_of_or_withinISOGcm1 (Mus musculus)1624291 PMID:14573516RGDPMID:14573516
Gcm1Ratastrocyte fate commitment acts_upstream_of_or_withinIEAUniProtKB:P70348 and ensembl:ENSMUSP000000241041600115GO_REF:0000107EnsemblGO_REF:0000107
Gcm1Ratbranching involved in labyrinthine layer morphogenesis acts_upstream_of_or_withinISOGcm1 (Mus musculus)1624291MGI:2183479 PMID:10888880RGDPMID:10888880
Gcm1Ratbranching involved in labyrinthine layer morphogenesis acts_upstream_of_or_withinIEAUniProtKB:P70348 and ensembl:ENSMUSP000000241041600115GO_REF:0000107EnsemblGO_REF:0000107
Gcm1Ratcell differentiation involved in embryonic placenta development acts_upstream_of_or_withinIEAUniProtKB:P70348 and ensembl:ENSMUSP000000241041600115GO_REF:0000107EnsemblGO_REF:0000107
Gcm1Ratcell differentiation involved in embryonic placenta development acts_upstream_of_or_withinISOGcm1 (Mus musculus)1624291MGI:2183479 PMID:10888880RGDPMID:10888880
Gcm1Ratcell differentiation involved in embryonic placenta development involved_inIBAMGI:108045 and PANTHER:PTN0002758141600115GO_REF:0000033GO_CentralGO_REF:0000033
Gcm1Ratgliogenesis involved_inIBAFB:FBgn0014179 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Gcm1Ratpositive regulation of DNA-templated transcription acts_upstream_of_or_withinISOGCM1 (Homo sapiens)1624291 PMID:27917469RGDPMID:27917469
Gcm1Ratpositive regulation of DNA-templated transcription acts_upstream_of_or_withinIEAUniProtKB:Q9NP62 and ensembl:ENSP000002598031600115GO_REF:0000107EnsemblGO_REF:0000107
Gcm1Ratpositive regulation of syncytium formation by plasma membrane fusion acts_upstream_of_or_withinIEAUniProtKB:P70348 and ensembl:ENSMUSP000000241041600115GO_REF:0000107EnsemblGO_REF:0000107
Gcm1Ratpositive regulation of syncytium formation by plasma membrane fusion acts_upstream_of_or_withinISOGcm1 (Mus musculus)1624291MGI:97308 PMID:21558372RGDPMID:21558372
Gcm1Ratpositive regulation of transcription by RNA polymerase II involved_inISOGCM1 (Homo sapiens)1624291 PMID:15385555RGDPMID:15385555
Gcm1Ratpositive regulation of transcription by RNA polymerase II acts_upstream_of_or_withinIEAUniProtKB:P70348 and ensembl:ENSMUSP000000241041600115GO_REF:0000107EnsemblGO_REF:0000107
Gcm1Ratpositive regulation of transcription by RNA polymerase II acts_upstream_of_or_withinISOGcm1 (Mus musculus)1624291MGI:2183479 PMID:23610556RGDPMID:23610556
Gcm1Ratpositive regulation of transcription by RNA polymerase II involved_inIEAUniProtKB:Q9NP62 and ensembl:ENSP000002598031600115GO_REF:0000107EnsemblGO_REF:0000107
Gcm1Ratregulation of cell differentiation involved in embryonic placenta development involved_inISOGCM1 (Homo sapiens)1624291 PMID:19219068RGDPMID:19219068
Gcm1Ratregulation of cell differentiation involved in embryonic placenta development involved_inIEAUniProtKB:Q9NP62 and ensembl:ENSP000002598031600115GO_REF:0000107EnsemblGO_REF:0000107
Gcm1Ratregulation of DNA-templated transcription  TAS 61603 RGD 
Gcm1Ratregulation of DNA-templated transcription involved_inIEAInterPro:IPR003902 more ...1600115GO_REF:0000002InterProGO_REF:0000002
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Cellular Component
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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gcm1Ratnucleus located_inISOGcm1 (Mus musculus)1624291 PMID:14573516RGDPMID:14573516
Gcm1Ratnucleus located_inIEAUniProtKB-KW:KW-05391600115GO_REF:0000043UniProtGO_REF:0000043
Gcm1Ratnucleus located_inIEAUniProtKB-SubCell:SL-01911600115GO_REF:0000044UniProtGO_REF:0000044
Gcm1Ratnucleus located_inIEAUniProtKB:Q9NP62 and ensembl:ENSP000002598031600115GO_REF:0000107EnsemblGO_REF:0000107
Gcm1Ratnucleus is_active_inIBAFB:FBgn0014179 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Gcm1Ratnucleus located_inISOGCM1 (Homo sapiens)1624291 PMID:23867755RGDPMID:23867755
Gcm1Ratnucleus located_inIEAUniProtKB:P70348 and ensembl:ENSMUSP000000241041600115GO_REF:0000107EnsemblGO_REF:0000107
Gcm1Rattranscription regulator complex part_ofISOGCM1 (Homo sapiens)1624291 PMID:15385555RGDPMID:15385555
Gcm1Rattranscription regulator complex part_ofIEAUniProtKB:Q9NP62 and ensembl:ENSP000002598031600115GO_REF:0000107EnsemblGO_REF:0000107
1 to 9 of 9 rows

Molecular Function
1 to 20 of 25 rows

  
Object Symbol
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Term
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Evidence
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Reference
Notes
Source
Original Reference(s)
Gcm1RatDNA binding enablesIEAInterPro:IPR003902 and InterPro:IPR0361151600115GO_REF:0000002InterProGO_REF:0000002
Gcm1RatDNA binding enablesIEAUniProtKB-KW:KW-02381600115GO_REF:0000043UniProtGO_REF:0000043
Gcm1RatDNA binding enablesISOGcm1 (Mus musculus)1624291 PMID:12297286RGDPMID:12297286
Gcm1RatDNA binding enablesIEAUniProtKB:P70348 and ensembl:ENSMUSP000000241041600115GO_REF:0000107EnsemblGO_REF:0000107
Gcm1RatDNA-binding transcription activator activity, RNA polymerase II-specific enablesISOGCM1 (Homo sapiens)1624291 PMID:15385555RGDPMID:15385555
Gcm1RatDNA-binding transcription activator activity, RNA polymerase II-specific enablesIEAInterPro:IPR0397911600115GO_REF:0000002InterProGO_REF:0000002
Gcm1RatDNA-binding transcription activator activity, RNA polymerase II-specific enablesIEAUniProtKB:Q9NP62 and ensembl:ENSP000002598031600115GO_REF:0000107EnsemblGO_REF:0000107
Gcm1RatDNA-binding transcription factor activity  TAS 61603 RGD 
Gcm1RatDNA-binding transcription factor activity enablesIEAUniProtKB:Q9NP62 and ensembl:ENSP000002598031600115GO_REF:0000107EnsemblGO_REF:0000107
Gcm1RatDNA-binding transcription factor activity enablesISOGCM1 (Homo sapiens)1624291 PMID:15385555RGDPMID:15385555
Gcm1RatDNA-binding transcription factor activity, RNA polymerase II-specific enablesISOGCM1 (Homo sapiens)1624291 PMID:23867755 and PMID:27917469RGDPMID:23867755 and PMID:27917469
Gcm1RatDNA-binding transcription factor activity, RNA polymerase II-specific enablesIEAUniProtKB:Q9NP62 and ensembl:ENSP000002598031600115GO_REF:0000107EnsemblGO_REF:0000107
Gcm1RatDNA-binding transcription factor activity, RNA polymerase II-specific enablesIBAFB:FBgn0014179 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Gcm1Rathistone deacetylase binding enablesISOGCM1 (Homo sapiens)1624291UniProtKB:Q9UQL6 and PMID:23867755RGDPMID:23867755
Gcm1Rathistone deacetylase binding enablesIEAUniProtKB:Q9NP62 and ensembl:ENSP000002598031600115GO_REF:0000107EnsemblGO_REF:0000107
Gcm1Ratmetal ion binding enablesIEAUniProtKB-KW:KW-04791600115GO_REF:0000043UniProtGO_REF:0000043
Gcm1Ratprotein binding enablesISOGCM1 (Homo sapiens)1624291UniProtKB:O60479 more ...RGDPMID:23651062 more ...
Gcm1Ratprotein binding enablesISOGcm1 (Mus musculus)1624291PR:P45481 PMID:21558372RGDPMID:21558372
Gcm1RatRNA polymerase II cis-regulatory region sequence-specific DNA binding enablesISOGCM1 (Homo sapiens)1624291 PMID:15385555RGDPMID:15385555
Gcm1RatRNA polymerase II cis-regulatory region sequence-specific DNA binding enablesIEAUniProtKB:Q9NP62 and ensembl:ENSP000002598031600115GO_REF:0000107EnsemblGO_REF:0000107
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#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Isolation and characterization of mammalian homologs of the Drosophila gene glial cells missing. Kim J, etal., Proc Natl Acad Sci U S A 1998 Oct 13;95(21):12364-9.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:10888880   PMID:12297286   PMID:14573516   PMID:15385555   PMID:19219068   PMID:21558372   PMID:23610556   PMID:23867755   PMID:27917469  



Gcm1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8887,805,993 - 87,819,229 (+)NCBIGRCr8
mRatBN7.2878,925,687 - 78,938,924 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl878,925,687 - 78,938,924 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx884,412,841 - 84,426,055 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0882,689,502 - 82,702,716 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0880,512,207 - 80,525,423 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0885,355,766 - 85,369,002 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl885,355,766 - 85,369,002 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0884,920,654 - 84,933,890 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4883,018,975 - 83,032,211 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1883,038,028 - 83,051,265 (+)NCBI
Celera878,670,476 - 78,683,712 (+)NCBICelera
Cytogenetic Map8q31NCBI
GCM1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38653,126,961 - 53,148,841 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl653,126,961 - 53,148,841 (-)EnsemblGRCh38hg38GRCh38
GRCh37652,991,759 - 53,013,639 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36653,099,721 - 53,121,586 (-)NCBINCBI36Build 36hg18NCBI36
Build 34653,099,720 - 53,121,586NCBI
Celera654,653,553 - 54,675,420 (-)NCBICelera
Cytogenetic Map6p12.1NCBI
HuRef652,823,388 - 52,845,251 (-)NCBIHuRef
CHM1_1652,993,522 - 53,015,402 (-)NCBICHM1_1
T2T-CHM13v2.0652,966,559 - 52,988,449 (-)NCBIT2T-CHM13v2.0
Gcm1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39977,959,240 - 77,972,906 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl977,959,206 - 77,972,906 (+)EnsemblGRCm39 Ensembl
GRCm38978,051,958 - 78,065,624 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl978,051,924 - 78,065,624 (+)EnsemblGRCm38mm10GRCm38
MGSCv37977,899,765 - 77,913,431 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36977,837,642 - 77,851,308 (+)NCBIMGSCv36mm8
Celera975,229,708 - 75,242,850 (+)NCBICelera
Cytogenetic Map9E1NCBI
cM Map943.49NCBI
Gcm1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554112,898,693 - 2,917,168 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554112,872,758 - 2,917,154 (+)NCBIChiLan1.0ChiLan1.0
GCM1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2567,597,729 - 67,619,569 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1663,474,401 - 63,496,262 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0652,681,528 - 52,703,367 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1654,319,737 - 54,341,582 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl654,319,744 - 54,341,582 (-)Ensemblpanpan1.1panPan2
GCM1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11220,623,593 - 20,642,861 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1220,623,717 - 20,640,193 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1220,517,343 - 20,562,563 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01221,120,964 - 21,166,452 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1221,120,940 - 21,140,877 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11220,625,674 - 20,671,144 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01220,730,476 - 20,775,852 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01220,868,003 - 20,913,270 (-)NCBIUU_Cfam_GSD_1.0
Gcm1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494656,221,801 - 56,235,619 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049364767,724,666 - 7,738,401 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GCM1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl746,767,498 - 46,791,037 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1746,767,498 - 46,798,317 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27134,509,950 - 134,516,913 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GCM1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11719,421,054 - 19,444,311 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1719,424,896 - 19,443,079 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604452,976,804 - 53,020,227 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gcm1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624850406,840 - 421,128 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624850405,001 - 421,208 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Gcm1
68 total Variants

Predicted Target Of
Summary Value
Count of predictions:45
Count of miRNA genes:38
Interacting mature miRNAs:41
Transcripts:ENSRNOT00000010583
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 57 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)871888757116888757Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)830848154101699754Rat
1298079Activ2Activity QTL 29.50.000001voluntary movement trait (VT:0003491)rearing measurement (CMO:0001515)84186687686866876Rat
70161Bp62Blood pressure QTL 622.90.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)84269268490165460Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)830848154101699754Rat
61464Niddm11Non-insulin dependent diabetes mellitus QTL 113.10.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)83558203280582032Rat
4889938Bss89Bone structure and strength QTL 893.8tibia size trait (VT:0100001)tibia cortical bone volume (CMO:0001725)85009524982460899Rat
1578755Pur5Proteinuria QTL 53.30.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)830848154101699754Rat
8662823Vetf5Vascular elastic tissue fragility QTL 51.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)82824291299525068Rat

1 to 10 of 57 rows



circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
2 19 8 11 5 3 5 2 52 5 17 42 16 6



Ensembl Acc Id: ENSRNOT00000010583   ⟹   ENSRNOP00000010583
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl878,925,687 - 78,938,924 (+)Ensembl
Rnor_6.0 Ensembl885,355,766 - 85,369,002 (+)Ensembl
RefSeq Acc Id: NM_017186   ⟹   NP_058882
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8887,805,993 - 87,819,229 (+)NCBI
mRatBN7.2878,925,687 - 78,938,924 (+)NCBI
Rnor_6.0885,355,766 - 85,369,002 (+)NCBI
Rnor_5.0884,920,654 - 84,933,890 (+)NCBI
RGSC_v3.4883,018,975 - 83,032,211 (+)RGD
Celera878,670,476 - 78,683,712 (+)RGD
Sequence:
Protein RefSeqs NP_058882 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC64783 (Get FASTA)   NCBI Sequence Viewer  
  EDL77757 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000010583
  ENSRNOP00000010583.1
GenBank Protein Q9Z288 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_058882   ⟸   NM_017186
- UniProtKB: Q9Z288 (UniProtKB/Swiss-Prot),   A6I1H0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000010583   ⟸   ENSRNOT00000010583
GCM

Name Modeler Protein Id AA Range Protein Structure
AF-Q9Z288-F1-model_v2 AlphaFold Q9Z288 1-436 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 22 of 22 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-29776 BioCyc
Ensembl Genes ENSRNOG00000007932 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000010583 ENTREZGENE
  ENSRNOT00000010583.3 UniProtKB/Swiss-Prot
Gene3D-CATH 2.20.25.670 UniProtKB/Swiss-Prot
  3.30.70.3530 UniProtKB/Swiss-Prot
InterPro GCM UniProtKB/Swiss-Prot
  GCM_dom_sf UniProtKB/Swiss-Prot
  GCM_large UniProtKB/Swiss-Prot
  GCM_small UniProtKB/Swiss-Prot
  Tscrpt_reg_GCM UniProtKB/Swiss-Prot
KEGG Report rno:29394 UniProtKB/Swiss-Prot
NCBI Gene 29394 ENTREZGENE
PANTHER CHORION-SPECIFIC TRANSCRIPTION FACTOR GCMA UniProtKB/Swiss-Prot
  PTHR12414 UniProtKB/Swiss-Prot
Pfam GCM UniProtKB/Swiss-Prot
PhenoGen Gcm1 PhenoGen
PROSITE GCM UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000007932 RatGTEx
Superfamily-SCOP SSF90073 UniProtKB/Swiss-Prot
UniProt A6I1H0 ENTREZGENE, UniProtKB/TrEMBL
  GCM1_RAT UniProtKB/Swiss-Prot, ENTREZGENE
1 to 22 of 22 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-12-04 Gcm1  glial cells missing transcription factor 1  Gcm1  glial cells missing homolog 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-02-03 Gcm1  glial cells missing homolog 1  Gcm1  glial cells missing homolog 1 (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-04-22 Gcm1  glial cells missing homolog 1 (Drosophila)  Gcma  glial cells missing (Drosophila) homolog a  Symbol and Name updated to reflect Human and Mouse nomenclature 625702 APPROVED
2002-06-10 Gcma  glial cells missing (Drosophila) homolog a      Name updated 70584 APPROVED
2001-12-06 Gcma  glial cells missing (Drosophila) homolog a      Symbol and Name updated to reflect Human and Mouse nomenclature 69665 APPROVED

Note Type Note Reference
gene_expression expressed during embryonic development 61603
gene_process transforms presumptive neurons into glia 61603