Klra17 (killer cell lectin-like receptor, subfamily A, member 17) - Rat Genome Database

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Gene: Klra17 (killer cell lectin-like receptor, subfamily A, member 17) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Klra17
Name: killer cell lectin-like receptor, subfamily A, member 17
RGD ID: 2291887
Description: Predicted to enable signaling receptor activity. Predicted to be involved in cell adhesion. Predicted to be located in plasma membrane. Predicted to be active in cell surface; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hypothetical protein LOC497796; LOC497796; Ly49 inhibitory receptor-like
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84165,522,631 - 165,550,502 (-)NCBIGRCr8
mRatBN7.24163,837,392 - 163,865,260 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4163,837,399 - 163,865,211 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4170,071,450 - 170,099,271 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04165,854,411 - 165,882,230 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04164,488,457 - 164,516,278 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04164,174,738 - 164,211,880 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4164,184,870 - 164,211,819 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04212,823,593 - 212,860,669 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44167,691,683 - 167,719,493 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera4152,509,161 - 152,536,966 (-)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 10 of 10 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Klra17Rat17beta-estradiol multiple interactionsEXP 6480464[estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of KLRA17 mRNACTDPMID:32741896
Klra17Rat17beta-estradiol 3-benzoate multiple interactionsEXP 6480464[estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of KLRA17 mRNACTDPMID:32741896
Klra17Ratacetamide increases expressionEXP 6480464acetamide results in increased expression of KLRA17 mRNACTDPMID:31881176
Klra17Ratbisphenol A affects expressionEXP 6480464bisphenol A affects the expression of KLRA17 mRNACTDPMID:25181051
Klra17Ratbisphenol A increases methylationEXP 6480464bisphenol A results in increased methylation of KLRA17 geneCTDPMID:28505145
Klra17Ratdecabromodiphenyl ether multiple interactionsEXP 6480464[Flame Retardants co-treated with pentabromodiphenyl ether co-treated with decabromobiphenyl ether co-treated with hexabromocyclododecane] results in more ...CTDPMID:32207525
Klra17Ratdecabromodiphenyl ether increases expressionEXP 6480464decabromobiphenyl ether results in increased expression of KLRA17 mRNACTDPMID:23914054
Klra17Rattestosterone multiple interactionsEXP 6480464[estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of KLRA17 mRNACTDPMID:32741896
Klra17Ratthioacetamide increases expressionEXP 6480464Thioacetamide results in increased expression of KLRA17 mRNACTDPMID:23411599
Klra17Ratvinclozolin decreases expressionEXP 6480464vinclozolin results in decreased expression of KLRA17 mRNACTDPMID:23034163

1 to 10 of 10 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Klra17Ratcell adhesion involved_inIEAUniProtKB-KW:KW-01301600115GO_REF:0000043UniProtGO_REF:0000043

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Klra17Ratcell surface is_active_inIBAMGI:101901|MGI:101904|MGI:101907|MGI:102968|PANTHER:PTN0005143361600115GO_REF:0000033GO_CentralGO_REF:0000033
Klra17Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Klra17Ratmembrane located_inIEAUniProtKB-SubCell:SL-01621600115GO_REF:0000044UniProtGO_REF:0000044
Klra17Ratplasma membrane located_inIEAARBA:ARBA000278011600115GO_REF:0000117UniProtGO_REF:0000117

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Klra17Ratcarbohydrate binding enablesIEAUniProtKB-KW:KW-04301600115GO_REF:0000043UniProtGO_REF:0000043
Klra17Ratsignaling receptor activity enablesIBAMGI:101907|PANTHER:PTN0005143361600115GO_REF:0000033GO_CentralGO_REF:0000033

PMID:12477932   PMID:15593300  



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Variants in Klra17
741 total Variants

1 to 10 of 35 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
6478754Anxrr43Anxiety related response QTL 430.14035locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4144639524182687754Rat
724558Plsm2Polydactyly-luxate syndrome (PLS) morphotypes QTL 20.0003hindlimb integrity trait (VT:0010563)hind foot phalanges count (CMO:0001949)4132422778177422778Rat
1582237Kidm34Kidney mass QTL 3440.0001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)4148090542168069246Rat
6478693Anxrr32Anxiety related response QTL 320.00092locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4144639524182687754Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)426775591168368347Rat
631683Bp116Blood pressure QTL 1160.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4124303370169303370Rat
61451Ciaa4CIA Autoantibody QTL 43.1blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)4126395976167139601Rat
1331738Bp209Blood pressure QTL 2092.979arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)4138503169179293946Rat
6478700Anxrr33Anxiety related response QTL 330.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
1298524Oia8Oil induced arthritis QTL 8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4138503169173369699Rat

1 to 10 of 35 rows
RH128758  
Rat AssemblyChrPosition (strand)SourceJBrowse
RH 3.4 Map41016.9UniSTS
Cytogenetic Map4q42UniSTS
AU046799  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24163,627,332 - 163,627,474 (+)MAPPERmRatBN7.2
mRatBN7.24163,845,440 - 163,845,586 (+)MAPPERmRatBN7.2
Rnor_6.04164,192,038 - 164,192,183NCBIRnor6.0
Rnor_6.04163,875,046 - 163,875,185NCBIRnor6.0
Rnor_5.04212,524,569 - 212,524,708UniSTSRnor5.0
Rnor_5.04212,840,853 - 212,840,998UniSTSRnor5.0
RGSC_v3.44167,490,705 - 167,490,844UniSTSRGSC3.4
RGSC_v3.44167,699,728 - 167,699,873UniSTSRGSC3.4
Celera4152,517,201 - 152,517,346UniSTS
Cytogenetic Map4q42UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 10 22 41 80 79 48 25 48 6 155 69 21 21 37 31



Ensembl Acc Id: ENSRNOT00000084796   ⟹   ENSRNOP00000069726
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4163,837,399 - 163,865,211 (-)Ensembl
Rnor_6.0 Ensembl4164,184,870 - 164,211,819 (-)Ensembl
RefSeq Acc Id: NM_001111310   ⟹   NP_001104780
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84165,522,631 - 165,550,444 (-)NCBI
mRatBN7.24163,837,396 - 163,865,211 (-)NCBI
Rnor_6.04164,184,867 - 164,211,819 (-)NCBI
Rnor_5.04212,823,593 - 212,860,669 (-)NCBI
RGSC_v3.44167,691,683 - 167,719,493 (-)RGD
Celera4152,509,161 - 152,536,966 (-)RGD
Sequence:
RefSeq Acc Id: XM_063286457   ⟹   XP_063142527
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84165,522,631 - 165,550,502 (-)NCBI
Protein RefSeqs NP_001104780 (Get FASTA)   NCBI Sequence Viewer  
  XP_063142527 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH93399 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000069726.2
RefSeq Acc Id: NP_001104780   ⟸   NM_001111310
- UniProtKB: Q566Q4 (UniProtKB/TrEMBL),   M0R6A0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000069726   ⟸   ENSRNOT00000084796
RefSeq Acc Id: XP_063142527   ⟸   XM_063286457
- Peptide Label: isoform X1
C-type lectin

Name Modeler Protein Id AA Range Protein Structure
AF-M0R6A0-F1-model_v2 AlphaFold M0R6A0 1-268 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13693442
Promoter ID:EPDNEW_R3967
Type:single initiation site
Name:LOC497796_1
Description:hypothetical protein LOC497796
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04164,211,826 - 164,211,886EPDNEW


1 to 26 of 26 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-42752 BioCyc
Ensembl Genes ENSRNOG00000060241 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000084796.2 UniProtKB/TrEMBL
Gene3D-CATH 3.10.100.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7389533 IMAGE-MGC_LOAD
InterPro C-type_lectin UniProtKB/TrEMBL
  C-type_lectin-like UniProtKB/TrEMBL
  C-type_lectin_fold UniProtKB/TrEMBL
  Ly49 UniProtKB/TrEMBL
  Mouse_KLRs UniProtKB/TrEMBL
  NKR-like_CTLD UniProtKB/TrEMBL
KEGG Report rno:497796 UniProtKB/TrEMBL
MGC_CLONE MGC:112762 IMAGE-MGC_LOAD
NCBI Gene 497796 ENTREZGENE
PANTHER KILLER CELL LECTIN-LIKE RECEPTOR 2 UniProtKB/TrEMBL
  KILLER CELL LECTIN-LIKE RECEPTOR, SUBFAMILY A, MEMBER 17 UniProtKB/TrEMBL
Pfam Lectin_C UniProtKB/TrEMBL
  Ly49 UniProtKB/TrEMBL
PhenoGen Klra17 PhenoGen
PROSITE C_TYPE_LECTIN_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000060241 RatGTEx
SMART CLECT UniProtKB/TrEMBL
Superfamily-SCOP C-type_lectin_fold UniProtKB/TrEMBL
UniProt M0R6A0 ENTREZGENE
  Q566Q4 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary M0R6A0 UniProtKB/TrEMBL
1 to 26 of 26 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Klra17  killer cell lectin-like receptor, subfamily A, member 17  LOC497796  hypothetical protein LOC497796  Symbol and Name Changed 1299863 APPROVED
2008-04-03 LOC497796  hypothetical protein LOC497796      Symbol and Name status set to provisional 70820 PROVISIONAL