Ube2e2 (ubiquitin-conjugating enzyme E2E 2) - Rat Genome Database

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Gene: Ube2e2 (ubiquitin-conjugating enzyme E2E 2) Rattus norvegicus
Analyze
Symbol: Ube2e2
Name: ubiquitin-conjugating enzyme E2E 2
RGD ID: 1305644
Description: Predicted to enable ISG15 transferase activity and ubiquitin conjugating enzyme activity. Predicted to be involved in protein modification by small protein conjugation. Predicted to act upstream of or within DNA damage response and positive regulation of G1/S transition of mitotic cell cycle. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human UBE2E2 (ubiquitin conjugating enzyme E2 E2); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; ubiquitin/proteasome degradation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC361013; ubiquitin-conjugating enzyme E2 E2; ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8159,411,067 - 9,688,731 (+)NCBIGRCr8
mRatBN7.2156,980,241 - 7,257,912 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl156,980,474 - 7,257,532 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx159,117,264 - 9,395,237 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01510,030,041 - 10,308,015 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0158,330,495 - 8,608,451 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0157,402,210 - 7,928,320 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl157,871,497 - 7,927,939 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01511,469,650 - 11,995,676 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4158,554,863 - 8,828,088 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1158,554,863 - 8,827,742 (+)NCBI
Celera157,042,822 - 7,313,674 (+)NCBICelera
Cytogenetic Map15p16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ube2e2Rattype 2 diabetes mellitus susceptibilityISOUBE2E2 (Homo sapiens)401850598associated with Environmental Illness and DNA:SNP:: (rs1496653) (human)RGD 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ube2e2Rathepatocellular adenoma  ISOUBE2E2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:27914986
Ube2e2Rathepatocellular carcinoma  ISOUBE2E2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:27914986
Ube2e2Rattype 2 diabetes mellitus  ISOUBE2E2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:20818381

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ube2e2Rat(1->4)-beta-D-glucan multiple interactionsISOUbe2e2 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of UBE2E2 mRNACTDPMID:36331819
Ube2e2Rat1,2-dimethylhydrazine decreases expressionISOUbe2e2 (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of UBE2E2 mRNACTDPMID:22206623
Ube2e2Rat1,2-dimethylhydrazine multiple interactionsISOUbe2e2 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of UBE2E2 mRNACTDPMID:22206623
Ube2e2Rat17beta-estradiol decreases expressionISOUBE2E2 (Homo sapiens)6480464Estradiol results in decreased expression of UBE2E2 mRNACTDPMID:21185374
Ube2e2Rat17beta-estradiol increases expressionISOUbe2e2 (Mus musculus)6480464Estradiol results in increased expression of UBE2E2 mRNACTDPMID:39298647
Ube2e2Rat2,3',4,4',5-Pentachlorobiphenyl increases expressionISOUbe2e2 (Mus musculus)64804642 more ...CTDPMID:31388691
Ube2e2Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOUbe2e2 (Mus musculus)6480464[Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of UBE2E2 mRNACTDPMID:16214954
Ube2e2Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOUbe2e2 (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of UBE2E2 mRNACTDPMID:18172886 more ...
Ube2e2Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOUbe2e2 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of UBE2E2 mRNACTDPMID:21570461
Ube2e2Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsEXP 6480464AHR protein alternative form affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of UBE2E2 mRNA]CTDPMID:21215274
Ube2e2Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of UBE2E2 mRNACTDPMID:21215274 and PMID:32109520
Ube2e2Rat2,3,7,8-Tetrachlorodibenzofuran decreases expressionEXP 64804642 more ...CTDPMID:32109520
Ube2e2Rat2,4-dinitrotoluene affects expressionEXP 64804642 and 4-dinitrotoluene affects the expression of UBE2E2 mRNACTDPMID:21346803
Ube2e2Rat4,4'-sulfonyldiphenol increases expressionISOUbe2e2 (Mus musculus)6480464bisphenol S results in increased expression of UBE2E2 mRNACTDPMID:39298647
Ube2e2Rataflatoxin B1 decreases expressionISOUbe2e2 (Mus musculus)6480464Aflatoxin B1 results in decreased expression of UBE2E2 mRNACTDPMID:19770486
Ube2e2Rataflatoxin B1 decreases methylationISOUBE2E2 (Homo sapiens)6480464Aflatoxin B1 results in decreased methylation of UBE2E2 geneCTDPMID:27153756
Ube2e2Ratamitrole decreases expressionEXP 6480464Amitrole results in decreased expression of UBE2E2 mRNACTDPMID:30047161
Ube2e2Rataristolochic acid A decreases expressionISOUBE2E2 (Homo sapiens)6480464aristolochic acid I results in decreased expression of UBE2E2 mRNACTDPMID:33212167
Ube2e2Ratarsane increases methylationISOUBE2E2 (Homo sapiens)6480464Arsenic results in increased methylation of UBE2E2 promoterCTDPMID:21291286
Ube2e2Ratarsane multiple interactionsISOUBE2E2 (Homo sapiens)6480464[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of UBE2E2 mRNACTDPMID:39836092

1 to 20 of 91 rows

Biological Process
1 to 11 of 11 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ube2e2RatDNA damage response acts_upstream_of_or_withinISOUBE2E2 (Homo sapiens)1624291 PMID:21628527RGDPMID:21628527
Ube2e2RatISG15-protein conjugation involved_inISOUBE2E2 (Homo sapiens)1624291 PMID:16428300RGDPMID:16428300
Ube2e2RatISG15-protein conjugation involved_inIBAPANTHER:PTN008604341 and UniProtKB:Q96LR51600115GO_REF:0000033GO_CentralGO_REF:0000033
Ube2e2Ratpositive regulation of G1/S transition of mitotic cell cycle acts_upstream_of_or_withinISOUBE2E2 (Homo sapiens)1624291UniProtKB:P38936 and PMID:21628527RGDPMID:21628527
Ube2e2Ratprotein K11-linked ubiquitination involved_inISOUBE2E2 (Homo sapiens)1624291 PMID:20061386RGDPMID:20061386
Ube2e2Ratprotein K11-linked ubiquitination involved_inIBAPANTHER:PTN008604341 and UniProtKB:Q96LR51600115GO_REF:0000033GO_CentralGO_REF:0000033
Ube2e2Ratprotein K48-linked ubiquitination involved_inISOUBE2E2 (Homo sapiens)1624291 PMID:20061386RGDPMID:20061386
Ube2e2Ratprotein K48-linked ubiquitination involved_inIBAPANTHER:PTN001529626 and UniProtKB:Q96LR51600115GO_REF:0000033GO_CentralGO_REF:0000033
Ube2e2Ratprotein K63-linked ubiquitination involved_inISOUBE2E2 (Homo sapiens)1624291 PMID:20061386RGDPMID:20061386
Ube2e2Ratprotein K63-linked ubiquitination involved_inIBAPANTHER:PTN008604341 and UniProtKB:Q96LR51600115GO_REF:0000033GO_CentralGO_REF:0000033
Ube2e2Ratprotein monoubiquitination involved_inISOUBE2E2 (Homo sapiens)1624291 PMID:27237050RGDPMID:27237050
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Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ube2e2Ratnucleus is_active_inIBAFB:FBgn0000173 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033

Molecular Function
1 to 10 of 10 rows

  
1 to 10 of 10 rows

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ube2e2RatEndoplasmic Reticulum-associated degradation pathway  IEA 6907045 KEGGrno:04141
Ube2e2Ratubiquitin/proteasome degradation pathway  IEA 6907045 KEGGrno:04120

BioCyc Pathways


#
Reference Title
Reference Citation
1. Air pollution and diabetes association: Modification by type 2 diabetes genetic risk score. Eze IC, etal., Environ Int. 2016 Sep;94:263-271. doi: 10.1016/j.envint.2016.04.032. Epub 2016 Jun 6.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:9371400   PMID:12477932   PMID:16428300   PMID:20061386   PMID:21628527   PMID:27914986  



Ube2e2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8159,411,067 - 9,688,731 (+)NCBIGRCr8
mRatBN7.2156,980,241 - 7,257,912 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl156,980,474 - 7,257,532 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx159,117,264 - 9,395,237 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01510,030,041 - 10,308,015 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0158,330,495 - 8,608,451 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0157,402,210 - 7,928,320 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl157,871,497 - 7,927,939 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01511,469,650 - 11,995,676 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4158,554,863 - 8,828,088 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1158,554,863 - 8,827,742 (+)NCBI
Celera157,042,822 - 7,313,674 (+)NCBICelera
Cytogenetic Map15p16NCBI
UBE2E2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38323,203,098 - 23,591,925 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl323,203,020 - 23,591,794 (+)EnsemblGRCh38hg38GRCh38
GRCh37323,244,589 - 23,633,416 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36323,219,812 - 23,607,074 (+)NCBINCBI36Build 36hg18NCBI36
Build 34323,219,811 - 23,607,074NCBI
Celera323,181,176 - 23,568,475 (+)NCBICelera
Cytogenetic Map3p24.3NCBI
HuRef323,195,983 - 23,578,212 (+)NCBIHuRef
CHM1_1323,196,572 - 23,584,124 (+)NCBICHM1_1
T2T-CHM13v2.0323,208,135 - 23,596,988 (+)NCBIT2T-CHM13v2.0
Ube2e2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39143,575,429 - 3,896,133 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl143,575,429 - 3,896,121 (+)EnsemblGRCm39 Ensembl
GRCm381418,573,563 - 18,894,284 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1418,573,575 - 18,894,267 (-)EnsemblGRCm38mm10GRCm38
MGSCv371419,406,091 - 19,726,141 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361417,366,703 - 17,686,753 (-)NCBIMGSCv36mm8
Celera1414,258,953 - 14,589,761 (-)NCBICelera
Cytogenetic Map14A1NCBI
cM Map147.08NCBI
Ube2e2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543015,122,377 - 15,441,523 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543015,122,373 - 15,442,264 (+)NCBIChiLan1.0ChiLan1.0
UBE2E2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2223,164,902 - 23,550,662 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1323,169,694 - 23,555,428 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0323,121,699 - 23,502,329 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1323,440,772 - 23,826,027 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl323,446,158 - 23,825,277 (+)Ensemblpanpan1.1panPan2
UBE2E2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12320,110,128 - 20,593,767 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2320,130,230 - 20,486,399 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2320,126,888 - 20,601,866 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02320,441,820 - 20,915,867 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2320,442,596 - 20,811,888 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12320,250,902 - 20,782,556 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02320,360,456 - 20,837,497 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02320,469,605 - 20,997,864 (-)NCBIUU_Cfam_GSD_1.0
Ube2e2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118181,850,218 - 182,142,077 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493647314,988,802 - 15,280,650 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UBE2E2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl139,998,199 - 10,380,556 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1139,998,097 - 10,380,564 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21311,329,305 - 11,329,480 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103241760
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11567,885,721 - 68,263,924 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604141,006,105 - 41,386,722 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

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Variants in Ube2e2
778 total Variants

Predicted Target Of
Summary Value
Count of predictions:291
Count of miRNA genes:191
Interacting mature miRNAs:213
Transcripts:ENSRNOT00000046879
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 12 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1641913Colcr2Colorectal carcinoma resistance QTL 26.570.0197intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)15226636822711984Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1530632945306329Rat
1582251Gluco24Glucose level QTL 243.20.0008blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)15553075650530756Rat
5684946Bss98Bone structure and strength QTL 983.90.0026tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)15105825014481294Rat
1354657Despr13Despair related QTL 130.0022locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)15129912054Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15142356671Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15155302115Rat
731170Pur3Proteinuria QTL 32.30.0005urine protein amount (VT:0005160)urine protein excretion rate (CMO:0000759)15141686771Rat
8552920Pigfal8Plasma insulin-like growth factor 1 level QTL 83blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)15134723002Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15226636846921453Rat

1 to 10 of 12 rows
D15Got11  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8159,612,921 - 9,613,202 (+)Marker Load Pipeline
mRatBN7.2157,182,101 - 7,182,382 (+)MAPPERmRatBN7.2
Rnor_6.0157,852,893 - 7,853,173NCBIRnor6.0
Rnor_5.01511,920,249 - 11,920,529UniSTSRnor5.0
RGSC_v3.4158,752,426 - 8,752,707RGDRGSC3.4
RGSC_v3.4158,752,427 - 8,752,707UniSTSRGSC3.4
RGSC_v3.1158,752,427 - 8,752,707RGD
Celera157,238,079 - 7,238,359UniSTS
RH 3.4 Map1595.3RGD
RH 3.4 Map1595.3UniSTS
RH 2.0 Map1550.7RGD
Cytogenetic Map15p16UniSTS
D15Mco16  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8158,687,763 - 8,687,912 (+)Marker Load Pipeline
mRatBN7.2156,256,908 - 6,257,057 (+)MAPPERmRatBN7.2
Rnor_6.0157,430,229 - 7,430,377NCBIRnor6.0
Rnor_5.01511,497,180 - 11,497,328UniSTSRnor5.0
RGSC_v3.4157,804,369 - 7,804,518RGDRGSC3.4
RGSC_v3.4157,804,370 - 7,804,518UniSTSRGSC3.4
RGSC_v3.1157,804,369 - 7,804,518RGD
Celera156,329,629 - 6,329,777UniSTS
Cytogenetic Map15p16UniSTS
D3S3993  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2157,257,660 - 7,257,908 (+)MAPPERmRatBN7.2
Rnor_6.0157,928,068 - 7,928,315NCBIRnor6.0
Rnor_5.01511,995,424 - 11,995,671UniSTSRnor5.0
RGSC_v3.4158,828,217 - 8,828,464UniSTSRGSC3.4
Celera157,313,803 - 7,314,050UniSTS
Cytogenetic Map15p16UniSTS
RH129032  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2157,493,152 - 7,493,356 (+)MAPPERmRatBN7.2
Rnor_6.0158,177,996 - 8,178,199NCBIRnor6.0
Rnor_5.01512,240,037 - 12,240,240UniSTSRnor5.0
RGSC_v3.4159,071,441 - 9,071,644UniSTSRGSC3.4
Celera157,546,445 - 7,546,648UniSTS
RH 3.4 Map1572.2UniSTS
Cytogenetic Map15p16UniSTS
D4Mit282  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.01511,884,198 - 11,884,360NCBIRnor5.0
Rnor_5.01511,884,216 - 11,884,360NCBIRnor5.0
RGSC_v3.4158,716,278 - 8,716,439UniSTSRGSC3.4
RGSC_v3.4158,716,296 - 8,716,439UniSTSRGSC3.4
Celera157,202,590 - 7,202,733UniSTS
Celera157,202,572 - 7,202,733UniSTS
Cytogenetic Map15p16UniSTS
AW532084  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2157,132,041 - 7,132,236 (+)MAPPERmRatBN7.2
Rnor_6.0157,802,900 - 7,803,094NCBIRnor6.0
Rnor_5.01511,870,256 - 11,870,450UniSTSRnor5.0
RGSC_v3.4158,702,335 - 8,702,529UniSTSRGSC3.4
Celera157,188,629 - 7,188,823UniSTS
RH 3.4 Map1593.3UniSTS
Cytogenetic Map15p16UniSTS
BE120096  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2157,452,809 - 7,452,989 (+)MAPPERmRatBN7.2
Rnor_6.0158,137,940 - 8,138,119NCBIRnor6.0
Rnor_5.01512,200,843 - 12,201,022UniSTSRnor5.0
RGSC_v3.4159,029,607 - 9,029,786UniSTSRGSC3.4
Celera157,508,068 - 7,508,247UniSTS
RH 3.4 Map1573.3UniSTS
Cytogenetic Map15p16UniSTS
RH141730  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2157,437,329 - 7,437,543 (+)MAPPERmRatBN7.2
Rnor_6.0158,122,464 - 8,122,677NCBIRnor6.0
Rnor_5.01512,185,520 - 12,185,733UniSTSRnor5.0
RGSC_v3.4159,014,055 - 9,014,268UniSTSRGSC3.4
Celera157,492,894 - 7,493,107UniSTS
RH 3.4 Map1591.7UniSTS
Cytogenetic Map15p16UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000046879   ⟹   ENSRNOP00000049082
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl156,986,277 - 7,257,532 (+)Ensembl
Rnor_6.0 Ensembl157,871,497 - 7,927,939 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000105543   ⟹   ENSRNOP00000087029
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl156,980,474 - 7,257,532 (+)Ensembl
RefSeq Acc Id: NM_001108371   ⟹   NP_001101841
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8159,411,620 - 9,688,731 (+)NCBI
mRatBN7.2156,980,794 - 7,257,912 (+)NCBI
Rnor_6.0157,402,247 - 7,927,939 (+)NCBI
Rnor_5.01511,469,650 - 11,995,676 (+)NCBI
RGSC_v3.4158,554,863 - 8,828,088 (+)RGD
Celera157,042,822 - 7,313,674 (+)RGD
Sequence:
RefSeq Acc Id: NM_001399659   ⟹   NP_001386588
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8159,411,067 - 9,688,731 (+)NCBI
mRatBN7.2156,980,241 - 7,257,912 (+)NCBI
RefSeq Acc Id: NM_001399660   ⟹   NP_001386589
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8159,411,067 - 9,688,731 (+)NCBI
mRatBN7.2156,980,241 - 7,257,912 (+)NCBI
RefSeq Acc Id: NM_001399661   ⟹   NP_001386590
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8159,411,620 - 9,688,731 (+)NCBI
mRatBN7.2156,980,794 - 7,257,912 (+)NCBI
1 to 10 of 10 rows
Protein RefSeqs NP_001101841 (Get FASTA)   NCBI Sequence Viewer  
  NP_001386588 (Get FASTA)   NCBI Sequence Viewer  
  NP_001386589 (Get FASTA)   NCBI Sequence Viewer  
  NP_001386590 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL94076 (Get FASTA)   NCBI Sequence Viewer  
  EDL94077 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000049082
  ENSRNOP00000049082.4
  ENSRNOP00000087029.1
  ENSRNOP00000103882
1 to 10 of 10 rows
RefSeq Acc Id: NP_001101841   ⟸   NM_001108371
- Peptide Label: isoform 1
- UniProtKB: D3ZYE1 (UniProtKB/TrEMBL),   A6K030 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000049082   ⟸   ENSRNOT00000046879
Ensembl Acc Id: ENSRNOP00000087029   ⟸   ENSRNOT00000105543
RefSeq Acc Id: NP_001386589   ⟸   NM_001399660
- Peptide Label: isoform 2
- UniProtKB: A0A8I6A2G8 (UniProtKB/TrEMBL),   A6K029 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001386588   ⟸   NM_001399659
- Peptide Label: isoform 2
- UniProtKB: A0A8I6A2G8 (UniProtKB/TrEMBL),   A6K029 (UniProtKB/TrEMBL)
UBC core

Name Modeler Protein Id AA Range Protein Structure
AF-D3ZYE1-F1-model_v2 AlphaFold D3ZYE1 1-126 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 32 of 32 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-14476 BioCyc
BioCyc Pathway PWY-7511 [protein ubiquitination] BioCyc
BioCyc Pathway Image PWY-7511 BioCyc
Ensembl Genes ENSRNOG00000032690 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000046879 ENTREZGENE
  ENSRNOT00000046879.4 UniProtKB/TrEMBL
  ENSRNOT00000105543.1 UniProtKB/TrEMBL
  ENSRNOT00000121480 ENTREZGENE
Gene3D-CATH 3.10.110.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7127579 IMAGE-MGC_LOAD
  IMAGE:7382303 IMAGE-MGC_LOAD
InterPro UBQ-conjugat_E2 UniProtKB/TrEMBL
  UBQ-conjugating_AS UniProtKB/TrEMBL
  UBQ-conjugating_enzyme/RWD UniProtKB/TrEMBL
KEGG Report rno:361013 UniProtKB/TrEMBL
MGC_CLONE MGC:116336 IMAGE-MGC_LOAD
  MGC:94146 IMAGE-MGC_LOAD
NCBI Gene 361013 ENTREZGENE
PANTHER UBIQUITIN-CONJUGATING ENZYME E2 UniProtKB/TrEMBL
Pfam UQ_con UniProtKB/TrEMBL
PhenoGen Ube2e2 PhenoGen
PROSITE UBIQUITIN_CONJUGAT_1 UniProtKB/TrEMBL
  UBIQUITIN_CONJUGAT_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000032690 RatGTEx
SMART UBCc UniProtKB/TrEMBL
Superfamily-SCOP SSF54495 UniProtKB/TrEMBL
UniProt A0A8I6A2G8 ENTREZGENE, UniProtKB/TrEMBL
  A6K029 ENTREZGENE, UniProtKB/TrEMBL
  A6K030 ENTREZGENE, UniProtKB/TrEMBL
  D3ZYE1 ENTREZGENE, UniProtKB/TrEMBL
  Q4KLJ5_RAT UniProtKB/TrEMBL
  Q6AY98_RAT UniProtKB/TrEMBL
1 to 32 of 32 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-05-24 Ube2e2  ubiquitin-conjugating enzyme E2E 2  LOC683661  similar to ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast)  Data merged from RGD:1584491 1643240 APPROVED
2011-08-01 Ube2e2  ubiquitin-conjugating enzyme E2E 2  Ube2e2  ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-19 LOC683661  similar to ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast)      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-12-06 Ube2e2  ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast)  Ube2e2_predicted  ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast) (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Ube2e2_predicted  ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast) (predicted)      Symbol and Name status set to approved 70820 APPROVED