Mast2 (microtubule associated serine/threonine kinase 2) - Rat Genome Database

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Pathways
Gene: Mast2 (microtubule associated serine/threonine kinase 2) Chinchilla lanigera
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Symbol: Mast2
Name: microtubule associated serine/threonine kinase 2
RGD ID: 9041406
Description: ENCODES a protein that exhibits ATP binding (ortholog); magnesium ion binding (ortholog); microtubule binding (ortholog); INVOLVED IN protein phosphorylation (ortholog); regulation of interleukin-12 production (ortholog); spermatid differentiation (ortholog); ASSOCIATED WITH acute myeloid leukemia (ortholog); Breast Cancer, Familial (ortholog); cervical cancer (ortholog); FOUND IN microtubule cytoskeleton (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: microtubule-associated serine/threonine-protein kinase 2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546412,264,252 - 12,459,124 (-)EnsemblChiLan1.0 Ensembl
ChiLan1.0NW_00495546412,264,252 - 12,459,061 (-)NCBIChiLan1.0ChiLan1.0
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Mast2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546412,264,252 - 12,459,124 (-)EnsemblChiLan1.0 Ensembl
ChiLan1.0NW_00495546412,264,252 - 12,459,061 (-)NCBIChiLan1.0ChiLan1.0
MAST2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38145,803,612 - 46,036,122 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl145,786,987 - 46,036,228 (+)EnsemblGRCh38.p14 Ensemblhg38GRCh38
GRCh37146,269,284 - 46,501,794 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36146,041,872 - 46,274,383 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34145,981,304 - 46,213,816NCBI
Celera144,556,926 - 44,789,085 (+)NCBICelera
Cytogenetic Map1p34.1NCBI
HuRef144,384,241 - 44,616,807 (+)NCBIHuRef
CHM1_1146,386,848 - 46,618,962 (+)NCBICHM1_1
T2T-CHM13v2.0145,680,810 - 45,913,311 (+)NCBIT2T-CHM13v2.0
Mast2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394116,163,957 - 116,321,420 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4116,161,623 - 116,321,544 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm384116,306,760 - 116,464,223 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4116,306,762 - 116,464,183 (-)EnsemblGRCm38.p6 Ensemblmm10GRCm38
MGSCv374115,979,367 - 116,136,788 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv364115,804,694 - 115,961,780 (-)NCBIMGSCv36mm8
Celera4115,047,241 - 115,204,176 (-)NCBICelera
Cytogenetic Map4D1NCBI
cM Map453.1NCBI
Mast2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85135,013,006 - 135,152,195 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5135,012,058 - 135,152,161 (-)EnsemblGRCr8
mRatBN7.25129,776,293 - 129,915,502 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5129,775,676 - 129,915,606 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5132,400,580 - 132,539,431 (-)NCBIUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05134,155,173 - 134,294,017 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05134,177,616 - 134,316,449 (-)NCBIUTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd5134,684,203 - 134,823,518 (-)NCBI
Lyon_Normotensive5136,661,758 - 136,801,068 (-)NCBI
Lyon_Hypertensive5135,848,953 - 135,988,267 (-)NCBI
F344_StmMcwi5129,401,164 - 129,546,730 (-)NCBI
Rnor_6.05135,149,336 - 135,285,337 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5135,149,307 - 135,285,337 (-)EnsemblRnor_6.0 Ensemblrn6Rnor6.0
Rnor_5.05138,932,728 - 139,079,273 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45136,573,518 - 136,717,367 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5128,304,199 - 128,444,930 (-)NCBICelera
RGSC_v3.15136,578,743 - 136,722,650 (-)NCBI
Cytogenetic Map5q35NCBI
MAST2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21180,769,555 - 181,007,609 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11179,911,130 - 180,151,035 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0145,105,098 - 45,341,903 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1146,461,462 - 46,696,110 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl146,461,456 - 46,696,053 (+)EnsemblPanPan1.1 EnsemblpanPan2panpan1.1
MAST2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11514,361,225 - 14,569,502 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1514,361,281 - 14,569,878 (-)EnsemblCanFam3.1 EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1514,482,881 - 14,690,932 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01514,513,937 - 14,723,687 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1514,513,937 - 14,723,829 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11514,314,235 - 14,522,219 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01514,382,721 - 14,590,981 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01514,452,409 - 14,660,885 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Mast2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mIctTri1.hap11133,666,797 - 33,852,567 (+)NCBImIctTri1.hap1
HiC_Itri_2NW_02440505861,080,403 - 61,266,105 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647426,905,083 - 27,091,333 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647426,905,217 - 27,090,886 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAST2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6165,406,878 - 165,619,933 (-)EnsemblSscrofa11.1 EnsemblsusScr11Sscrofa11.1
Sscrofa11.16165,406,876 - 165,620,029 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26152,918,925 - 153,063,852 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MAST2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mChlSab1.0.hap12090,833,481 - 91,096,282 (-)NCBImChlSab1.0.hap1
Vero_WHO_p1.0NW_02366603329,968,453 - 30,231,930 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ChlSab1.12086,752,553 - 87,006,712 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2086,752,703 - 87,006,697 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Mast2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249061,668,877 - 1,949,466 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
HetGla_female_1.0 EnsemblNW_0046249061,668,923 - 1,949,466 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
Naked mole-rat maternal Ensembl76,371,864 - 6,706,908 (-)Ensembl
Mast2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1139,977,463 - 40,118,069 (-)NCBIRrattus_CSIRO_v1Rrattus_CSIRO_v1


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005398689 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013521600 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013521601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013521602 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013521603 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013521604 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AGCD01050189 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01050190 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01050191 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01050192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01050193 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01050194 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01050195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01050196 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01050197 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GBDI01218447 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GBDJ01389195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCLAT00000014791   ⟹   ENSCLAP00000014632
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495546412,264,252 - 12,459,124 (-)Ensembl
Ensembl Acc Id: ENSCLAT00000014792   ⟹   ENSCLAP00000014633
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495546412,289,877 - 12,424,658 (-)Ensembl
RefSeq Acc Id: XM_005398689   ⟹   XP_005398746
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495546412,264,252 - 12,459,061 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013521600   ⟹   XP_013377054
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495546412,264,252 - 12,459,061 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013521601   ⟹   XP_013377055
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495546412,264,252 - 12,459,061 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013521602   ⟹   XP_013377056
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495546412,264,252 - 12,459,061 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013521603   ⟹   XP_013377057
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495546412,264,252 - 12,459,061 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013521604   ⟹   XP_013377058
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495546412,264,252 - 12,459,061 (-)NCBI
Sequence:
RefSeq Acc Id: XP_005398746   ⟸   XM_005398689
- Peptide Label: isoform X2
- UniProtKB: A0A8C2VM77 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013377058   ⟸   XM_013521604
- Peptide Label: isoform X6
- UniProtKB: A0A8C2VM77 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013377057   ⟸   XM_013521603
- Peptide Label: isoform X5
- UniProtKB: A0A8C2VM77 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013377055   ⟸   XM_013521601
- Peptide Label: isoform X3
- UniProtKB: A0A8C2VM77 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013377056   ⟸   XM_013521602
- Peptide Label: isoform X4
- UniProtKB: A0A8C2VM77 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013377054   ⟸   XM_013521600
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VM77 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000014632   ⟸   ENSCLAT00000014791
Ensembl Acc Id: ENSCLAP00000014633   ⟸   ENSCLAT00000014792

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000010103 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000014791 ENTREZGENE
  ENSCLAT00000014791.1 UniProtKB/TrEMBL
  ENSCLAT00000014792.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1480.20 UniProtKB/TrEMBL
  2.30.42.10 UniProtKB/TrEMBL
  Phosphorylase Kinase, domain 1 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro AGC-kinase_C UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  MA_Ser/Thr_Kinase_dom UniProtKB/TrEMBL
  MAST UniProtKB/TrEMBL
  MAST_pre-PK_dom_sf UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
  PDZ_6 UniProtKB/TrEMBL
  PDZ_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
  Ser_Thr_kinase_AGC UniProtKB/TrEMBL
NCBI Gene Mast2 ENTREZGENE
PANTHER PTHR24356:SF136 UniProtKB/TrEMBL
  SERINE/THREONINE-PROTEIN KINASE UniProtKB/TrEMBL
Pfam DUF1908 UniProtKB/TrEMBL
  PDZ_6 UniProtKB/TrEMBL
  Pkinase UniProtKB/TrEMBL
PROSITE AGC_KINASE_CTER UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
SMART PDZ UniProtKB/TrEMBL
  S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF140482 UniProtKB/TrEMBL
  SSF50156 UniProtKB/TrEMBL
  SSF56112 UniProtKB/TrEMBL
UniProt A0A8C2VGW2_CHILA UniProtKB/TrEMBL
  A0A8C2VM77 ENTREZGENE, UniProtKB/TrEMBL