MIR6889 (microRNA 6889) - Rat Genome Database

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Gene: MIR6889 (microRNA 6889) Homo sapiens
Analyze
Symbol: MIR6889
Name: microRNA 6889
RGD ID: 8551428
HGNC Page HGNC:50014
Description: Located in extracellular exosome.
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: hsa-mir-6889
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382241,252,992 - 41,253,050 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2241,252,992 - 41,253,050 (-)EnsemblGRCh38hg38GRCh38
GRCh372241,648,996 - 41,649,054 (-)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map22q13.2NCBI
HuRef2224,613,458 - 24,613,516 (-)NCBIHuRef
CHM1_12241,608,683 - 41,608,741 (-)NCBICHM1_1
T2T-CHM13v2.02241,727,920 - 41,727,978 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:16381832   PMID:22955976   PMID:31926946  


Genomics


Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 22q11.1-13.33(chr22:16916608-50739836)x3 copy number gain See cases [RCV000133646] Chr22:16916608..50739836 [GRCh38]
Chr22:17397498..51178264 [GRCh37]
Chr22:15777498..49525130 [NCBI36]
Chr22:22q11.1-13.33		 pathogenic
GRCh38/hg38 22q11.1-13.33(chr22:16916743-50739785)x3 copy number gain See cases [RCV000134730] Chr22:16916743..50739785 [GRCh38]
Chr22:17397633..51178213 [GRCh37]
Chr22:15777633..49525079 [NCBI36]
Chr22:22q11.1-13.33		 pathogenic
GRCh38/hg38 22q13.1-13.33(chr22:40202014-50735806)x3 copy number gain See cases [RCV000134513] Chr22:40202014..50735806 [GRCh38]
Chr22:40598018..51174234 [GRCh37]
Chr22:38927964..49521100 [NCBI36]
Chr22:22q13.1-13.33		 pathogenic
GRCh38/hg38 22q13.2(chr22:40769910-41360090)x3 copy number gain See cases [RCV000134514] Chr22:40769910..41360090 [GRCh38]
Chr22:41165914..41756094 [GRCh37]
Chr22:39495860..40086040 [NCBI36]
Chr22:22q13.2		 uncertain significance
GRCh38/hg38 22q13.2(chr22:41251925-41281290)x3 copy number gain See cases [RCV000135916] Chr22:41251925..41281290 [GRCh38]
Chr22:41647929..41677294 [GRCh37]
Chr22:39977875..40007240 [NCBI36]
Chr22:22q13.2		 benign
GRCh38/hg38 22q12.3-13.33(chr22:33768441-50739977)x3 copy number gain See cases [RCV000051682] Chr22:33768441..50739977 [GRCh38]
Chr22:34164428..51178405 [GRCh37]
Chr22:32494428..49525271 [NCBI36]
Chr22:22q12.3-13.33		 pathogenic
GRCh38/hg38 22q12.3-13.33(chr22:37061769-50738932)x3 copy number gain See cases [RCV000051684] Chr22:37061769..50738932 [GRCh38]
Chr22:37457809..51177360 [GRCh37]
Chr22:35787755..49524226 [NCBI36]
Chr22:22q12.3-13.33		 pathogenic
GRCh38/hg38 22q13.2(chr22:40860894-41306006)x3 copy number gain See cases [RCV000050897] Chr22:40860894..41306006 [GRCh38]
Chr22:41256898..41702010 [GRCh37]
Chr22:39586844..40031956 [NCBI36]
Chr22:22q13.2		 uncertain significance
NC_000022.10:g.(?_41264983)_(41729217_?)dup duplication Nephronophthisis-like nephropathy 1 [RCV000556646] Chr22:40868979..41333213 [GRCh38]
Chr22:41264983..41729217 [GRCh37]
Chr22:22q13.2		 uncertain significance
miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:59792
Count of gene targets:20469
Count of transcripts:48195
Interacting mature miRNAs:hsa-miR-6889-3p, hsa-miR-6889-5p
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
10 99 26 35 199 58 180 2 21 181 19 93 341 246 37 109 37 90 161 9

Sequence


Ensembl Acc Id: ENST00000613185
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2241,252,992 - 41,253,050 (-)Ensembl
RefSeq Acc Id: NR_106949
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382241,252,992 - 41,253,050 (-)NCBI
HuRef2224,613,458 - 24,613,516 (-)NCBI
CHM1_12241,608,683 - 41,608,741 (-)NCBI
T2T-CHM13v2.02241,727,920 - 41,727,978 (-)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
COSMIC MIR6889 COSMIC
Ensembl Genes ENSG00000274552 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000613185 ENTREZGENE
GTEx ENSG00000274552 GTEx
HGNC ID HGNC:50014 ENTREZGENE
Human Proteome Map MIR6889 Human Proteome Map
miRBase MI0022736 ENTREZGENE
NCBI Gene MIR6889 ENTREZGENE
RNAcentral URS000075C76B RNACentral
  URS000075D99E RNACentral
  URS000075F059 RNACentral