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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Sctr | Mouse | 1,2-dichloroethane | affects expression | EXP | | 6480464 | ethylene dichloride affects the expression of SCTR mRNA | CTD | PMID:28960355 | Sctr | Mouse | 1,2-dimethylhydrazine | multiple interactions | ISO | Sctr (Rattus norvegicus) | 6480464 | [APC protein affects the susceptibility to 1 and 2-Dimethylhydrazine] which results in decreased expression of SCTR mRNA | CTD | PMID:27840820 | Sctr | Mouse | 1-naphthyl isothiocyanate | increases expression | ISO | Sctr (Rattus norvegicus) | 6480464 | 1-Naphthylisothiocyanate results in increased expression of SCTR mRNA | CTD | PMID:30723492 | Sctr | Mouse | 17alpha-ethynylestradiol | affects expression | ISO | Sctr (Rattus norvegicus) | 6480464 | Ethinyl Estradiol affects the expression of SCTR mRNA | CTD | PMID:15834898 | Sctr | Mouse | 17beta-estradiol | multiple interactions | ISO | Sctr (Rattus norvegicus) | 6480464 | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of SCTR mRNA | CTD | PMID:32741896 | Sctr | Mouse | 17beta-estradiol 3-benzoate | multiple interactions | ISO | Sctr (Rattus norvegicus) | 6480464 | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of SCTR mRNA | CTD | PMID:32741896 | Sctr | Mouse | 2,2',4,4'-Tetrabromodiphenyl ether | increases expression | ISO | Sctr (Rattus norvegicus) | 6480464 | 2 more ... | CTD | PMID:27291303 | Sctr | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Sctr (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of SCTR mRNA | CTD | PMID:22298810 | Sctr | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Sctr (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SCTR mRNA | CTD | PMID:33387578 | Sctr | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of SCTR mRNA | CTD | PMID:21570461 | Sctr | Mouse | 2-acetamidofluorene | increases expression | ISO | Sctr (Rattus norvegicus) | 6480464 | 2-Acetylaminofluorene results in increased expression of SCTR mRNA | CTD | PMID:17187413 | Sctr | Mouse | 4-hydroxyphenyl retinamide | decreases expression | EXP | | 6480464 | Fenretinide results in decreased expression of SCTR mRNA | CTD | PMID:28973697 | Sctr | Mouse | 6-propyl-2-thiouracil | increases expression | ISO | Sctr (Rattus norvegicus) | 6480464 | Propylthiouracil results in increased expression of SCTR mRNA | CTD | PMID:22504374 | Sctr | Mouse | acetamide | increases expression | ISO | Sctr (Rattus norvegicus) | 6480464 | acetamide results in increased expression of SCTR mRNA | CTD | PMID:31881176 | Sctr | Mouse | aflatoxin B1 | increases expression | ISO | Sctr (Rattus norvegicus) | 6480464 | Aflatoxin B1 results in increased expression of SCTR mRNA | CTD | PMID:25378103 and PMID:33354967 | Sctr | Mouse | aflatoxin B1 | increases methylation | ISO | SCTR (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of SCTR intron | CTD | PMID:30157460 | Sctr | Mouse | all-trans-retinoic acid | affects expression | ISO | SCTR (Homo sapiens) | 6480464 | Tretinoin affects the expression of SCTR mRNA | CTD | PMID:31600526 | Sctr | Mouse | ammonium chloride | affects expression | ISO | Sctr (Rattus norvegicus) | 6480464 | Ammonium Chloride affects the expression of SCTR mRNA | CTD | PMID:16483693 | Sctr | Mouse | antirheumatic drug | decreases expression | ISO | SCTR (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of SCTR mRNA | CTD | PMID:24449571 | Sctr | Mouse | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of SCTR mRNA | CTD | PMID:22228805 | Sctr | Mouse | benzo[a]pyrene | increases methylation | ISO | SCTR (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of SCTR exon | CTD | PMID:27901495 | Sctr | Mouse | benzo[a]pyrene | affects methylation | ISO | SCTR (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of SCTR promoter | CTD | PMID:27901495 | Sctr | Mouse | Benzo[ghi]perylene | increases expression | EXP | | 6480464 | 1 and 12-benzoperylene results in increased expression of SCTR mRNA | CTD | PMID:26377693 | Sctr | Mouse | beta-naphthoflavone | multiple interactions | ISO | Sctr (Rattus norvegicus) | 6480464 | [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SCTR mRNA | CTD | PMID:18164116 | Sctr | Mouse | bisphenol A | increases expression | ISO | Sctr (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of SCTR mRNA | CTD | PMID:27178563 more ... | Sctr | Mouse | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of SCTR promoter | CTD | PMID:27312807 | Sctr | Mouse | bisphenol A | decreases expression | ISO | Sctr (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of SCTR mRNA | CTD | PMID:25181051 and PMID:32145629 | Sctr | Mouse | bisphenol A | multiple interactions | ISO | Sctr (Rattus norvegicus) | 6480464 | Genistein promotes the reaction [bisphenol A results in increased expression of SCTR mRNA] | CTD | PMID:27178563 | Sctr | Mouse | cadmium atom | decreases expression | ISO | SCTR (Homo sapiens) | 6480464 | Cadmium results in decreased expression of SCTR mRNA | CTD | PMID:21120746 | Sctr | Mouse | cadmium atom | multiple interactions | EXP | | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SCTR mRNA | CTD | PMID:37325564 | Sctr | Mouse | cadmium atom | multiple interactions | ISO | SCTR (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SCTR mRNA | CTD | PMID:35301059 | Sctr | Mouse | cadmium dichloride | multiple interactions | ISO | SCTR (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SCTR mRNA | CTD | PMID:35301059 | Sctr | Mouse | cadmium dichloride | multiple interactions | EXP | | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SCTR mRNA | CTD | PMID:37325564 | Sctr | Mouse | carbon nanotube | increases expression | ISO | Sctr (Rattus norvegicus) | 6480464 | Nanotubes and Carbon results in increased expression of SCTR mRNA | CTD | PMID:19836432 | Sctr | Mouse | CGP 52608 | multiple interactions | ISO | SCTR (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to SCTR gene] | CTD | PMID:28238834 | Sctr | Mouse | cobalt dichloride | decreases expression | ISO | Sctr (Rattus norvegicus) | 6480464 | cobaltous chloride results in decreased expression of SCTR mRNA | CTD | PMID:24386269 | Sctr | Mouse | copper atom | decreases expression | ISO | Sctr (Rattus norvegicus) | 6480464 | Copper results in decreased expression of SCTR mRNA | CTD | PMID:30556269 | Sctr | Mouse | copper(0) | decreases expression | ISO | Sctr (Rattus norvegicus) | 6480464 | Copper results in decreased expression of SCTR mRNA | CTD | PMID:30556269 | Sctr | Mouse | cyclosporin A | decreases expression | ISO | SCTR (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of SCTR mRNA | CTD | PMID:27989131 | Sctr | Mouse | decabromodiphenyl ether | decreases expression | ISO | Sctr (Rattus norvegicus) | 6480464 | decabromobiphenyl ether results in decreased expression of SCTR mRNA | CTD | PMID:23914054 | Sctr | Mouse | dibutyl phthalate | decreases expression | ISO | Sctr (Rattus norvegicus) | 6480464 | Dibutyl Phthalate results in decreased expression of SCTR mRNA | CTD | PMID:15620428 | Sctr | Mouse | dichlorine | multiple interactions | ISO | Sctr (Rattus norvegicus) | 6480464 | [Ozone co-treated with Chlorine] results in increased expression of SCTR mRNA | CTD | PMID:18636392 | Sctr | Mouse | endosulfan | decreases expression | ISO | Sctr (Rattus norvegicus) | 6480464 | Endosulfan results in decreased expression of SCTR mRNA | CTD | PMID:29391264 | Sctr | Mouse | furan | increases expression | ISO | Sctr (Rattus norvegicus) | 6480464 | furan results in increased expression of SCTR mRNA | CTD | PMID:27387713 | Sctr | Mouse | genistein | multiple interactions | ISO | Sctr (Rattus norvegicus) | 6480464 | [Genistein co-treated with Methoxychlor] results in increased expression of SCTR mRNA and Genistein promotes the reaction [bisphenol A results in increased expression of SCTR mRNA] | CTD | PMID:21782745 and PMID:27178563 | Sctr | Mouse | gentamycin | decreases expression | ISO | Sctr (Rattus norvegicus) | 6480464 | Gentamicins results in decreased expression of SCTR mRNA | CTD | PMID:33387578 | Sctr | Mouse | indole-3-methanol | affects expression | ISO | Sctr (Rattus norvegicus) | 6480464 | indole-3-carbinol affects the expression of SCTR mRNA | CTD | PMID:21396975 | Sctr | Mouse | methimazole | increases expression | ISO | Sctr (Rattus norvegicus) | 6480464 | Methimazole results in increased expression of SCTR mRNA | CTD | PMID:22504374 | Sctr | Mouse | methoxychlor | multiple interactions | ISO | Sctr (Rattus norvegicus) | 6480464 | [Genistein co-treated with Methoxychlor] results in increased expression of SCTR mRNA | CTD | PMID:21782745 | Sctr | Mouse | methoxychlor | increases expression | ISO | Sctr (Rattus norvegicus) | 6480464 | Methoxychlor results in increased expression of SCTR mRNA | CTD | PMID:21782745 | Sctr | Mouse | N-nitrosodiethylamine | increases expression | EXP | | 6480464 | Diethylnitrosamine results in increased expression of SCTR mRNA | CTD | PMID:17942915 | Sctr | Mouse | N-nitrosodiethylamine | multiple interactions | ISO | Sctr (Rattus norvegicus) | 6480464 | [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SCTR mRNA | CTD | PMID:18164116 | Sctr | Mouse | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of SCTR mRNA] | CTD | PMID:17942915 | Sctr | Mouse | nickel atom | decreases expression | ISO | SCTR (Homo sapiens) | 6480464 | Nickel results in decreased expression of SCTR mRNA | CTD | PMID:24768652 and PMID:25583101 | Sctr | Mouse | nickel dichloride | affects expression | ISO | Sctr (Rattus norvegicus) | 6480464 | nickel chloride affects the expression of SCTR mRNA | CTD | PMID:22110744 | Sctr | Mouse | Nonylphenol | decreases expression | ISO | Sctr (Rattus norvegicus) | 6480464 | nonylphenol results in decreased expression of SCTR mRNA | CTD | PMID:15620428 | Sctr | Mouse | ozone | multiple interactions | ISO | Sctr (Rattus norvegicus) | 6480464 | [Ozone co-treated with Chlorine] results in increased expression of SCTR mRNA | CTD | PMID:18636392 | Sctr | Mouse | paracetamol | decreases expression | ISO | SCTR (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of SCTR mRNA | CTD | PMID:29067470 | Sctr | Mouse | paracetamol | decreases expression | ISO | Sctr (Rattus norvegicus) | 6480464 | Acetaminophen results in decreased expression of SCTR mRNA | CTD | PMID:33387578 | Sctr | Mouse | pirinixic acid | multiple interactions | EXP | | 6480464 | NCF1 protein promotes the reaction [pirinixic acid results in decreased expression of SCTR mRNA] | CTD | PMID:17950772 | Sctr | Mouse | pirinixic acid | decreases expression | EXP | | 6480464 | pirinixic acid results in decreased expression of SCTR mRNA | CTD | PMID:17950772 | Sctr | Mouse | resveratrol | multiple interactions | ISO | SCTR (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of SCTR mRNA | CTD | PMID:23557933 | Sctr | Mouse | rotenone | increases expression | ISO | Sctr (Rattus norvegicus) | 6480464 | Rotenone results in increased expression of SCTR mRNA | CTD | PMID:28374803 | Sctr | Mouse | silicon dioxide | increases expression | ISO | Sctr (Rattus norvegicus) | 6480464 | Silicon Dioxide results in increased expression of SCTR mRNA | CTD | PMID:34779285 | Sctr | Mouse | testosterone | multiple interactions | ISO | Sctr (Rattus norvegicus) | 6480464 | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of SCTR mRNA | CTD | PMID:32741896 | Sctr | Mouse | tetrachloromethane | increases expression | ISO | Sctr (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in increased expression of SCTR mRNA | CTD | PMID:31150632 | Sctr | Mouse | thioacetamide | increases expression | ISO | Sctr (Rattus norvegicus) | 6480464 | Thioacetamide results in increased expression of SCTR mRNA | CTD | PMID:34492290 | Sctr | Mouse | titanium dioxide | decreases expression | EXP | | 6480464 | titanium dioxide results in decreased expression of SCTR mRNA | CTD | PMID:35295148 | Sctr | Mouse | trichloroethene | decreases expression | ISO | Sctr (Rattus norvegicus) | 6480464 | Trichloroethylene results in decreased expression of SCTR mRNA | CTD | PMID:33387578 | Sctr | Mouse | triclosan | increases expression | ISO | SCTR (Homo sapiens) | 6480464 | Triclosan results in increased expression of SCTR mRNA | CTD | PMID:30510588 | Sctr | Mouse | valproic acid | decreases expression | ISO | SCTR (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of SCTR mRNA | CTD | PMID:29154799 | Sctr | Mouse | zoledronic acid | decreases expression | ISO | SCTR (Homo sapiens) | 6480464 | zoledronic acid results in decreased expression of SCTR mRNA | CTD | PMID:24714768 | |