ZNF891 (zinc finger protein 891) - Rat Genome Database

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Gene: ZNF891 (zinc finger protein 891) Homo sapiens
Analyze
Symbol: ZNF891
Name: zinc finger protein 891
RGD ID: 7242309
HGNC Page HGNC:38709
Description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hCG1646157
RGD Orthologs
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812133,104,779 - 133,130,274 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12133,104,779 - 133,130,274 (-)EnsemblGRCh38hg38GRCh38
GRCh3712133,681,365 - 133,706,860 (-)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map12q24.33NCBI
HuRef12130,475,700 - 130,486,210 (-)NCBIHuRef
CHM1_112133,516,487 - 133,526,992 (-)NCBICHM1_1
T2T-CHM13v2.012133,162,095 - 133,187,590 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IBA,IEA)

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11181995   PMID:12477932   PMID:15489334   PMID:16344560   PMID:16541075   PMID:21873635   PMID:26186194   PMID:28514442   PMID:29507755   PMID:30021884  


Genomics

Comparative Map Data
ZNF891
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812133,104,779 - 133,130,274 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12133,104,779 - 133,130,274 (-)EnsemblGRCh38hg38GRCh38
GRCh3712133,681,365 - 133,706,860 (-)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map12q24.33NCBI
HuRef12130,475,700 - 130,486,210 (-)NCBIHuRef
CHM1_112133,516,487 - 133,526,992 (-)NCBICHM1_1
T2T-CHM13v2.012133,162,095 - 133,187,590 (-)NCBIT2T-CHM13v2.0
Znf891
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495548286,692 - 96,745 (+)NCBIChiLan1.0ChiLan1.0
ZNF891
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210141,217,046 - 141,242,709 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112141,218,934 - 141,239,226 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012130,599,520 - 130,610,515 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112135,202,205 - 135,213,618 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12135,202,943 - 135,204,577 (-)Ensemblpanpan1.1panPan2
Znf891
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118121,839,065 - 121,846,270 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049366602,874,228 - 2,882,015 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZNF891
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1422,502,777 - 22,525,677 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11422,502,738 - 22,521,865 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ZNF891
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111128,419,257 - 128,425,834 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037116,361,730 - 116,372,849 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Znf891
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474728,356,472 - 28,369,331 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ZNF891
19 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 12q24.23-24.33(chr12:118165459-133182322)x3 copy number gain See cases [RCV000050866] Chr12:118165459..133182322 [GRCh38]
Chr12:118603264..133758908 [GRCh37]
Chr12:117087647..132268981 [NCBI36]
Chr12:12q24.23-24.33		 pathogenic
GRCh38/hg38 12q24.33(chr12:131924544-133191400)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051346]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051346]|See cases [RCV000051346] Chr12:131924544..133191400 [GRCh38]
Chr12:132409089..133767986 [GRCh37]
Chr12:130975042..132278059 [NCBI36]
Chr12:12q24.33		 pathogenic
GRCh38/hg38 12q24.31-24.33(chr12:123444758-133191400)x3 copy number gain See cases [RCV000051151] Chr12:123444758..133191400 [GRCh38]
Chr12:123929305..133767986 [GRCh37]
Chr12:122495258..132278059 [NCBI36]
Chr12:12q24.31-24.33		 pathogenic
GRCh38/hg38 12q24.32-24.33(chr12:126403612-133166920)x3 copy number gain See cases [RCV000053715] Chr12:126403612..133166920 [GRCh38]
Chr12:126888158..133743506 [GRCh37]
Chr12:125454111..132253579 [NCBI36]
Chr12:12q24.32-24.33		 pathogenic
GRCh38/hg38 12q24.33(chr12:131049491-133191400)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053717]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053717]|See cases [RCV000053717] Chr12:131049491..133191400 [GRCh38]
Chr12:131534036..133767986 [GRCh37]
Chr12:130099989..132278059 [NCBI36]
Chr12:12q24.33		 pathogenic
GRCh38/hg38 12q24.21-24.33(chr12:115131583-133166920)x3 copy number gain See cases [RCV000053689] Chr12:115131583..133166920 [GRCh38]
Chr12:115569388..133743506 [GRCh37]
Chr12:114053771..132253579 [NCBI36]
Chr12:12q24.21-24.33		 pathogenic
GRCh38/hg38 12q24.23-24.33(chr12:119417382-133191400)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053691]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053691]|See cases [RCV000053691] Chr12:119417382..133191400 [GRCh38]
Chr12:119855187..133767986 [GRCh37]
Chr12:118339570..132278059 [NCBI36]
Chr12:12q24.23-24.33		 pathogenic
GRCh38/hg38 12q24.31-24.33(chr12:123365769-133191400)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053693]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053693]|See cases [RCV000053693] Chr12:123365769..133191400 [GRCh38]
Chr12:123850316..133767986 [GRCh37]
Chr12:122416269..132278059 [NCBI36]
Chr12:12q24.31-24.33		 pathogenic
GRCh38/hg38 12q24.33(chr12:132576614-133191400)x1 copy number loss See cases [RCV000133777] Chr12:132576614..133191400 [GRCh38]
Chr12:133153200..133767986 [GRCh37]
Chr12:131663273..132278059 [NCBI36]
Chr12:12q24.33		 pathogenic
GRCh38/hg38 12q24.33(chr12:131650542-133191400)x1 copy number loss See cases [RCV000134173] Chr12:131650542..133191400 [GRCh38]
Chr12:132135087..133767986 [GRCh37]
Chr12:130701040..132278059 [NCBI36]
Chr12:12q24.33		 pathogenic
GRCh38/hg38 12q24.33(chr12:133102300-133182263)x3 copy number gain See cases [RCV000135146] Chr12:133102300..133182263 [GRCh38]
Chr12:133678886..133758849 [GRCh37]
Chr12:132188959..132268922 [NCBI36]
Chr12:12q24.33		 likely benign
GRCh38/hg38 12q24.31-24.33(chr12:123509825-133191400)x3 copy number gain See cases [RCV000135535] Chr12:123509825..133191400 [GRCh38]
Chr12:123994372..133767986 [GRCh37]
Chr12:122560325..132278059 [NCBI36]
Chr12:12q24.31-24.33		 pathogenic
GRCh38/hg38 12q24.31-24.33(chr12:120697672-133202490)x3 copy number gain See cases [RCV000137651] Chr12:120697672..133202490 [GRCh38]
Chr12:121135475..133779076 [GRCh37]
Chr12:119619858..132289149 [NCBI36]
Chr12:12q24.31-24.33		 pathogenic
GRCh38/hg38 12q24.33(chr12:132966304-133202490)x1 copy number loss See cases [RCV000137311] Chr12:132966304..133202490 [GRCh38]
Chr12:133542890..133779076 [GRCh37]
Chr12:132052963..132289149 [NCBI36]
Chr12:12q24.33		 likely benign|uncertain significance
GRCh38/hg38 12p13.33-q24.33(chr12:121271-133196807)x3 copy number gain See cases [RCV000139555] Chr12:121271..133196807 [GRCh38]
Chr12:282465..133773393 [GRCh37]
Chr12:100698..132283466 [NCBI36]
Chr12:12p13.33-q24.33		 pathogenic
GRCh38/hg38 12q24.21-24.33(chr12:114268403-133201316)x3 copy number gain See cases [RCV000143656] Chr12:114268403..133201316 [GRCh38]
Chr12:114706208..133777902 [GRCh37]
Chr12:113190591..132287975 [NCBI36]
Chr12:12q24.21-24.33		 pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:1-133851895)x3 copy number gain See cases [RCV000258805] Chr12:1..133851895 [GRCh37]
Chr12:12p13.33-q24.33		 pathogenic|likely pathogenic
GRCh37/hg19 12q24.33(chr12:131749518-133777902)x1 copy number loss See cases [RCV000449052] Chr12:131749518..133777902 [GRCh37]
Chr12:12q24.33		 pathogenic
GRCh37/hg19 12q24.33(chr12:132382041-133777902)x1 copy number loss See cases [RCV000446819] Chr12:132382041..133777902 [GRCh37]
Chr12:12q24.33		 pathogenic
GRCh37/hg19 12q24.33(chr12:133324869-133777902)x3 copy number gain See cases [RCV000446483] Chr12:133324869..133777902 [GRCh37]
Chr12:12q24.33		 pathogenic
GRCh37/hg19 12q24.33(chr12:133683528-133772989)x3 copy number gain See cases [RCV000447703] Chr12:133683528..133772989 [GRCh37]
Chr12:12q24.33		 likely benign
GRCh37/hg19 12q24.33(chr12:131862310-133777902)x1 copy number loss See cases [RCV000447834] Chr12:131862310..133777902 [GRCh37]
Chr12:12q24.33		 pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:173787-133777902)x3 copy number gain See cases [RCV000510482] Chr12:173787..133777902 [GRCh37]
Chr12:12p13.33-q24.33		 pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:173787-133777902) copy number gain See cases [RCV000511643] Chr12:173787..133777902 [GRCh37]
Chr12:12p13.33-q24.33		 pathogenic
NM_003440.4(ZNF140):c.1003A>G (p.Arg335Gly) single nucleotide variant not specified [RCV004295262] Chr12:133106280 [GRCh38]
Chr12:133682866 [GRCh37]
Chr12:12q24.33		 uncertain significance
GRCh37/hg19 12q24.33(chr12:133046203-133777902)x3 copy number gain See cases [RCV000512177] Chr12:133046203..133777902 [GRCh37]
Chr12:12q24.33		 uncertain significance
GRCh37/hg19 12q24.33(chr12:130973400-133777902)x3 copy number gain not provided [RCV000683469] Chr12:130973400..133777902 [GRCh37]
Chr12:12q24.33		 likely pathogenic
GRCh37/hg19 12q24.23-24.33(chr12:120367241-133777645)x3 copy number gain not provided [RCV000738070] Chr12:120367241..133777645 [GRCh37]
Chr12:12q24.23-24.33		 pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:621220-133779118)x3 copy number gain not provided [RCV000750253] Chr12:621220..133779118 [GRCh37]
Chr12:12p13.33-q24.33		 pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:191619-133777645)x3 copy number gain not provided [RCV000750246] Chr12:191619..133777645 [GRCh37]
Chr12:12p13.33-q24.33		 pathogenic
GRCh37/hg19 12q24.33(chr12:131363916-133777645)x3 copy number gain See cases [RCV000790570] Chr12:131363916..133777645 [GRCh37]
Chr12:12q24.33		 pathogenic
GRCh37/hg19 12q24.31-24.33(chr12:125451405-133810935) copy number gain not provided [RCV000767827] Chr12:125451405..133810935 [GRCh37]
Chr12:12q24.31-24.33		 pathogenic
GRCh37/hg19 12q24.33(chr12:132975658-133777902)x1 copy number loss not provided [RCV000847172] Chr12:132975658..133777902 [GRCh37]
Chr12:12q24.33		 uncertain significance
GRCh37/hg19 12q24.32-24.33(chr12:126470636-133777902)x1 copy number loss not provided [RCV000848702] Chr12:126470636..133777902 [GRCh37]
Chr12:12q24.32-24.33		 uncertain significance
NM_003440.4(ZNF140):c.1334A>C (p.Asn445Thr) single nucleotide variant not specified [RCV004292625] Chr12:133106611 [GRCh38]
Chr12:133683197 [GRCh37]
Chr12:12q24.33		 uncertain significance
GRCh37/hg19 12q24.22-24.33(chr12:117461902-133841395)x3 copy number gain Neurodevelopmental disorder with nonspecific brain abnormalities and with or without seizures [RCV001801213] Chr12:117461902..133841395 [GRCh37]
Chr12:12q24.22-24.33		 likely pathogenic
GRCh37/hg19 12q24.33(chr12:133520357-133777902)x1 copy number loss not provided [RCV001829100] Chr12:133520357..133777902 [GRCh37]
Chr12:12q24.33		 likely benign
NM_003440.4(ZNF140):c.1048A>G (p.Ile350Val) single nucleotide variant not specified [RCV004135127] Chr12:133106325 [GRCh38]
Chr12:133682911 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003440.4(ZNF140):c.746A>T (p.Glu249Val) single nucleotide variant not specified [RCV004224259] Chr12:133106023 [GRCh38]
Chr12:133682609 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003440.4(ZNF140):c.872A>T (p.His291Leu) single nucleotide variant not specified [RCV004232182] Chr12:133106149 [GRCh38]
Chr12:133682735 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003440.4(ZNF140):c.835G>A (p.Gly279Ser) single nucleotide variant not specified [RCV004154780] Chr12:133106112 [GRCh38]
Chr12:133682698 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003440.4(ZNF140):c.424G>A (p.Val142Ile) single nucleotide variant not specified [RCV004146090] Chr12:133105701 [GRCh38]
Chr12:133682287 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003440.4(ZNF140):c.271A>G (p.Lys91Glu) single nucleotide variant not specified [RCV004174205] Chr12:133105548 [GRCh38]
Chr12:133682134 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003440.4(ZNF140):c.876G>T (p.Gln292His) single nucleotide variant not specified [RCV004177062] Chr12:133106153 [GRCh38]
Chr12:133682739 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003440.4(ZNF140):c.932G>T (p.Arg311Leu) single nucleotide variant not specified [RCV004244367] Chr12:133106209 [GRCh38]
Chr12:133682795 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003440.4(ZNF140):c.934C>T (p.Arg312Cys) single nucleotide variant not specified [RCV004235803] Chr12:133106211 [GRCh38]
Chr12:133682797 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003440.4(ZNF140):c.983C>G (p.Pro328Arg) single nucleotide variant not specified [RCV004206630] Chr12:133106260 [GRCh38]
Chr12:133682846 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003440.4(ZNF140):c.935G>A (p.Arg312His) single nucleotide variant not specified [RCV004224805] Chr12:133106212 [GRCh38]
Chr12:133682798 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003440.4(ZNF140):c.713C>T (p.Thr238Met) single nucleotide variant not specified [RCV004197865] Chr12:133105990 [GRCh38]
Chr12:133682576 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003440.4(ZNF140):c.413G>A (p.Arg138Lys) single nucleotide variant not specified [RCV004076694] Chr12:133105690 [GRCh38]
Chr12:133682276 [GRCh37]
Chr12:12q24.33		 uncertain significance
GRCh37/hg19 12q24.31-24.33(chr12:121551496-133777902)x3 copy number gain not provided [RCV003484881] Chr12:121551496..133777902 [GRCh37]
Chr12:12q24.31-24.33		 pathogenic
GRCh37/hg19 12q24.31-24.33(chr12:120880079-133777902)x3 copy number gain not provided [RCV003484880] Chr12:120880079..133777902 [GRCh37]
Chr12:12q24.31-24.33		 pathogenic
NM_003440.4(ZNF140):c.1066C>T (p.Leu356Phe) single nucleotide variant not specified [RCV004489342] Chr12:133106343 [GRCh38]
Chr12:133682929 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003440.4(ZNF140):c.908G>C (p.Cys303Ser) single nucleotide variant not specified [RCV004489344] Chr12:133106185 [GRCh38]
Chr12:133682771 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003440.4(ZNF140):c.1060G>A (p.Glu354Lys) single nucleotide variant not specified [RCV004489341] Chr12:133106337 [GRCh38]
Chr12:133682923 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003440.4(ZNF140):c.1090A>C (p.Lys364Gln) single nucleotide variant not specified [RCV004687475] Chr12:133106367 [GRCh38]
Chr12:133682953 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003440.4(ZNF140):c.668A>C (p.Asn223Thr) single nucleotide variant not specified [RCV004687474] Chr12:133105945 [GRCh38]
Chr12:133682531 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003440.4(ZNF140):c.994A>C (p.Asn332His) single nucleotide variant not specified [RCV004687476] Chr12:133106271 [GRCh38]
Chr12:133682857 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003440.4(ZNF140):c.869G>A (p.Arg290His) single nucleotide variant not specified [RCV004687473] Chr12:133106146 [GRCh38]
Chr12:133682732 [GRCh37]
Chr12:12q24.33		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1283
Count of miRNA genes:573
Interacting mature miRNAs:634
Transcripts:ENST00000397313, ENST00000537226
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407286180GWAS935156_Hbrain measurement QTL GWAS935156 (human)4e-15brain measurementbrain measurement (CMO:0000911)12133112121133112122Human
407263525GWAS912501_Hbrain measurement QTL GWAS912501 (human)3e-10brain measurementbrain measurement (CMO:0000911)12133112121133112122Human
407069623GWAS718599_Heducational attainment QTL GWAS718599 (human)8e-08educational attainment12133112121133112122Human
407268898GWAS917874_Hbrain measurement QTL GWAS917874 (human)4e-12brain measurementbrain measurement (CMO:0000911)12133112121133112122Human
407166018GWAS814994_Hbrain measurement QTL GWAS814994 (human)3e-09cerebral cortex morphology trait (VT:0000788)tibia-fibula cortical bone total cross-sectional area (CMO:0001721)12133112121133112122Human
407294000GWAS942976_Hcortical thickness QTL GWAS942976 (human)5e-14cortical thickness12133112121133112122Human
407009333GWAS658309_HAbnormality of refraction QTL GWAS658309 (human)1e-12Abnormality of refraction12133107735133107736Human
407005967GWAS654943_Hintraocular pressure measurement QTL GWAS654943 (human)4e-08intraocular pressure measurement12133112121133112122Human
407054588GWAS703564_HBMI-adjusted waist-hip ratio QTL GWAS703564 (human)2e-11cortical thickness12133112121133112122Human

Markers in Region
SHGC-78788  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3712133,696,509 - 133,696,836UniSTSGRCh37
Build 3612132,206,582 - 132,206,909RGDNCBI36
Celera12133,396,806 - 133,397,133RGD
Cytogenetic Map12q24.33UniSTS
HuRef12130,475,654 - 130,475,981UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2438 2788 2253 4973 1726 2350 6 624 1947 465 2269 7298 6467 53 3734 1 849 1744 1616 175 1

Sequence


Ensembl Acc Id: ENST00000537226   ⟹   ENSP00000437590
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12133,104,779 - 133,130,274 (-)Ensembl
Ensembl Acc Id: ENST00000650709   ⟹   ENSP00000499213
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12133,106,830 - 133,130,273 (-)Ensembl
RefSeq Acc Id: NM_001277291   ⟹   NP_001264220
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812133,104,779 - 133,130,274 (-)NCBI
T2T-CHM13v2.012133,162,095 - 133,187,590 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001264220 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein A8MT65 (Get FASTA)   NCBI Sequence Viewer  
  EAW54793 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000437590
  ENSP00000437590.1
  ENSP00000499213.1
Ensembl Acc Id: ENSP00000499213   ⟸   ENST00000650709
Ensembl Acc Id: ENSP00000437590   ⟸   ENST00000537226
RefSeq Acc Id: NP_001264220   ⟸   NM_001277291
- UniProtKB: A8MT65 (UniProtKB/Swiss-Prot)
- Sequence:
Protein Domains
C2H2-type   KRAB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A8MT65-F1-model_v2 AlphaFold A8MT65 1-544 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:38709 AgrOrtholog
COSMIC ZNF891 COSMIC
Ensembl Genes ENSG00000214029 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000537226 ENTREZGENE
  ENST00000537226.3 UniProtKB/Swiss-Prot
  ENST00000650709.1 UniProtKB/TrEMBL
Gene3D-CATH 6.10.140.140 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000214029 GTEx
HGNC ID HGNC:38709 ENTREZGENE
Human Proteome Map ZNF891 Human Proteome Map
InterPro KRAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KRAB_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:101060200 UniProtKB/Swiss-Prot
NCBI Gene ZNF891 ENTREZGENE
PANTHER RCG31665-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC FINGER AND SCAN DOMAIN-CONTAINING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam KRAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-C2H2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-C2H2_6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-H2C2_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA166049034 PharmGKB
PROSITE KRAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART KRAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF109640 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57667 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A494C1V2_HUMAN UniProtKB/TrEMBL
  A8MT65 ENTREZGENE, UniProtKB/Swiss-Prot