MIR4804 (microRNA 4804) - Rat Genome Database

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Gene: MIR4804 (microRNA 4804) Homo sapiens
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Symbol: MIR4804
Name: microRNA 4804
RGD ID: 5134187
HGNC Page HGNC:41720
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38572,878,591 - 72,878,663 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl572,878,591 - 72,878,663 (+)EnsemblGRCh38hg38GRCh38
GRCh37572,174,418 - 72,174,490 (+)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map5q13.2NCBI
HuRef567,379,850 - 67,379,922 (+)NCBIHuRef
CHM1_1571,607,192 - 71,607,264 (+)NCBICHM1_1
T2T-CHM13v2.0573,359,760 - 73,359,832 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
MIR4804Human2-hydroxypropanoic acid increases expressionEXP 6480464Lactic Acid results in increased expression of MIR4804 mRNACTDPMID:30851411
MIR4804Humanrac-lactic acid increases expressionEXP 6480464Lactic Acid results in increased expression of MIR4804 mRNACTDPMID:30851411
MIR4804Humansodium arsenite increases expressionEXP 6480464sodium arsenite results in increased expression of MIR4804 mRNACTDPMID:25879800

PMID:16381832   PMID:21199797  



.

1 to 2 of 2 rows
Name
Type
Condition(s)
Position(s)
Clinical significance
GRCh38/hg38 5p15.33-q13.3(chr5:22149-74412725)x3 copy number gain See cases [RCV000138780] Chr5:22149..74412725 [GRCh38]
Chr5:22149..73708550 [GRCh37]
Chr5:75149..73744306 [NCBI36]
Chr5:5p15.33-q13.3		 pathogenic
GRCh38/hg38 5q11.2-13.2(chr5:58785203-73519962)x1 copy number loss Intellectual disability [RCV000984869] Chr5:58785203..73519962 [GRCh38]
Chr5:5q11.2-13.2		 likely pathogenic
1 to 2 of 2 rows

Predicted Targets
Summary Value
Count of predictions:11904
Count of gene targets:6114
Count of transcripts:10722
Interacting mature miRNAs:hsa-miR-4804-3p, hsa-miR-4804-5p
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.




adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
6 64 8 8 125 53 123 3 30 180 33 77 312 218 34 68 52 78 86 1


RefSeq Transcripts NR_039968 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC008953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENST00000581683
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl572,878,591 - 72,878,663 (+)Ensembl
RefSeq Acc Id: NR_039968
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38572,878,591 - 72,878,663 (+)NCBI
GRCh37572,174,418 - 72,174,490 (+)ENTREZGENE
HuRef567,379,850 - 67,379,922 (+)ENTREZGENE
CHM1_1571,607,192 - 71,607,264 (+)NCBI
T2T-CHM13v2.0573,359,760 - 73,359,832 (+)NCBI
Sequence:


1 to 11 of 11 rows
Database
Acc Id
Source(s)
COSMIC MIR4804 COSMIC
Ensembl Genes ENSG00000263593 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000581683 ENTREZGENE
GTEx ENSG00000263593 GTEx
HGNC ID HGNC:41720 ENTREZGENE
Human Proteome Map MIR4804 Human Proteome Map
miRBase MI0017452 ENTREZGENE
NCBI Gene 100616152 ENTREZGENE
RNAcentral URS00000D41D9 RNACentral
  URS0000325AF9 RNACentral
  URS0000759EA5 RNACentral
1 to 11 of 11 rows