DUX4L5 (double homeobox 4 like 5 (pseudogene)) - Rat Genome Database

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Gene: DUX4L5 (double homeobox 4 like 5 (pseudogene)) Homo sapiens
Analyze
No known orthologs.
Symbol: DUX4L5
Name: double homeobox 4 like 5 (pseudogene)
RGD ID: 4108582
HGNC Page HGNC:38689
Description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in chromatin. Predicted to be active in nucleus.
Type: pseudo (Ensembl: unprocessed_pseudogene)
RefSeq Status: INFERRED
Previously known as: double homeobox 4 like 5; double homeobox protein 4-like protein 5; double homeobox, 4-like
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Related Functional Gene: DUX4  
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384190,077,818 - 190,079,102 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4190,077,818 - 190,079,092 (+)EnsemblGRCh38hg38GRCh38
GRCh374190,998,973 - 191,000,257 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364191,232,660 - 191,234,270 (+)NCBINCBI36Build 36hg18NCBI36
Celera4188,235,231 - 188,238,428 (-)NCBICelera
Cytogenetic Map4q35.2NCBI
CHM1_14190,988,575 - 190,989,789 (+)NCBICHM1_1
T2T-CHM13v2.04193,445,949 - 193,447,233 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
aflatoxin B1  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
chromatin  (ISA)
nucleus  (IBA,IEA)

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7739628   PMID:10433963   PMID:11245978   PMID:17588759   PMID:17668377   PMID:17984056  


Genomics

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1101
Count of miRNA genes:660
Interacting mature miRNAs:754
Transcripts:ENST00000554668, ENST00000557283, ENST00000605696
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2292972PRSTS190_HProstate tumor susceptibility QTL 190 (human)4.130.0018Prostate tumor susceptibility4175186665190214555Human


Expression

RNA-SEQ Expression

endoderm
mesenchyme
mesoderm
respiratory system
1 1 1 1

Sequence


Ensembl Acc Id: ENST00000630834
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl4190,077,818 - 190,079,092 (+)Ensembl
RefSeq Acc Id: NM_001127389   ⟹   NP_001120861
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh384190,077,721 - 190,079,100 (+)NCBI
GRCh374190,998,876 - 191,000,255 (+)NCBI
RefSeq Acc Id: XM_006726416   ⟹   XP_006726479
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
CHM1_14190,988,575 - 190,989,846 (+)NCBI
RefSeq Acc Id: XM_928008
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
Build 364191,232,660 - 191,234,270 (+)NCBI Archive
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P0CJ88-F1-model_v2 AlphaFold P0CJ88 1-424 view protein structure


Additional Information

Database Acc Id Source(s)
COSMIC DUX4L5 COSMIC
Ensembl Genes ENSG00000280799 Ensembl, ENTREZGENE
Gene3D-CATH Homeodomain-like UniProtKB/Swiss-Prot
GTEx ENSG00000280799 GTEx
HGNC ID HGNC:38689 ENTREZGENE
Human Proteome Map DUX4L5 Human Proteome Map
InterPro Homeobox-like_sf UniProtKB/Swiss-Prot
  Homeobox_dom UniProtKB/Swiss-Prot
  Homeobox_regulator UniProtKB/Swiss-Prot
  HTH_motif UniProtKB/Swiss-Prot
NCBI Gene 653545 ENTREZGENE
PANTHER DOUBLE HOMEOBOX PROTEIN 1-RELATED UniProtKB/Swiss-Prot
  MIX-TYPE HOMEOBOX GENE 1-RELATED UniProtKB/Swiss-Prot
Pfam Homeodomain UniProtKB/Swiss-Prot
PharmGKB PA165663829 PharmGKB
PRINTS HTHREPRESSR UniProtKB/Swiss-Prot
PROSITE HOMEOBOX_2 UniProtKB/Swiss-Prot
SMART HOX UniProtKB/Swiss-Prot
Superfamily-SCOP SSF46689 UniProtKB/Swiss-Prot
UniProt DU4L5_HUMAN UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-10-30 DUX4L5  double homeobox 4 like 5 (pseudogene)    double homeobox 4 like 5  Symbol and/or name change 5135510 APPROVED