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Gene: FLJ33534 (Putative uncharacterized protein FLJ33534) Homo sapiens

Analyze

Symbol:

FLJ33534 (Ensembl: AC062028.1)

Name:

Putative uncharacterized protein FLJ33534 (Ensembl:novel transcript)

RGD ID:

4108107

Description:

Type:

ncrna (Ensembl: lncRNA)

RefSeq Status:

VALIDATED

Previously known as:

AC062028.1; MGC133163; uncharacterized LOC285150

Allele / Splice:

See ClinVar data

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	11,099,851 - 11,132,176 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	11,105,317 - 11,132,821 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	11,239,977 - 11,272,302 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	11,179,081 - 11,190,398 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	2	11,173,731 - 11,188,762 (-)	NCBI		Celera
Cytogenetic Map	2	p25.1	NCBI
HuRef	2	11,090,556 - 11,122,135 (-)	NCBI		HuRef
CHM1_1	2	11,169,628 - 11,201,912 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	2	11,131,309 - 11,164,568 (-)	NCBI		T2T-CHM13v2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

References

Additional References at PubMed

PMID:12477932	PMID:14702039	PMID:23251661	PMID:23319000	PMID:26278006

Genomics

Variants

Variants in FLJ33534
2 total Variants

Clinical Variants

Name	Type	Condition(s)	Position(s)	Clinical significance
GRCh38/hg38 2p25.3-23.2(chr2:30341-28419664)x3	copy number gain	See cases [RCV000135398]	Chr2:30341..28419664 [GRCh38] Chr2:30341..28642531 [GRCh37] Chr2:20341..28496035 [NCBI36] Chr2:2p25.3-23.2	pathogenic
GRCh38/hg38 2p25.3-23.3(chr2:17019-26318846)x3	copy number gain	See cases [RCV000137344]	Chr2:17019..26318846 [GRCh38] Chr2:17019..26541714 [GRCh37] Chr2:7019..26395218 [NCBI36] Chr2:2p25.3-23.3	pathogenic
GRCh38/hg38 2p25.3-24.1(chr2:1664615-23664142)x3	copy number gain	See cases [RCV000137913]	Chr2:1664615..23664142 [GRCh38] Chr2:1668387..23887012 [GRCh37] Chr2:1647394..23740517 [NCBI36] Chr2:2p25.3-24.1	pathogenic\|likely pathogenic
GRCh38/hg38 2p25.3-24.1(chr2:17019-20001056)x3	copy number gain	See cases [RCV000141226]	Chr2:17019..20001056 [GRCh38] Chr2:17019..20200817 [GRCh37] Chr2:7019..20064298 [NCBI36] Chr2:2p25.3-24.1	pathogenic
GRCh38/hg38 2p25.3-22.3(chr2:12770-33711509)x3	copy number gain	See cases [RCV000141829]	Chr2:12770..33711509 [GRCh38] Chr2:12770..33936576 [GRCh37] Chr2:2770..33790080 [NCBI36] Chr2:2p25.3-22.3	pathogenic
GRCh38/hg38 2p25.3-23.3(chr2:12770-25039694)x3	copy number gain	See cases [RCV000141877]	Chr2:12770..25039694 [GRCh38] Chr2:12770..25262563 [GRCh37] Chr2:2770..25116067 [NCBI36] Chr2:2p25.3-23.3	pathogenic
GRCh38/hg38 2p25.1-11.2(chr2:7495123-87705899)x3	copy number gain	See cases [RCV000141494]	Chr2:7495123..87705899 [GRCh38] Chr2:7635254..88005418 [GRCh37] Chr2:7552705..87786533 [NCBI36] Chr2:2p25.1-11.2	benign
GRCh38/hg38 2p25.1-24.3(chr2:10790663-14417134)x3	copy number gain	See cases [RCV000142512]	Chr2:10790663..14417134 [GRCh38] Chr2:10930789..14557258 [GRCh37] Chr2:10848240..14474709 [NCBI36] Chr2:2p25.1-24.3	pathogenic
GRCh38/hg38 2p25.3-21(chr2:236816-45983232)x3	copy number gain	See cases [RCV000143682]	Chr2:236816..45983232 [GRCh38] Chr2:236816..46210371 [GRCh37] Chr2:226816..46063875 [NCBI36] Chr2:2p25.3-21	pathogenic
GRCh38/hg38 2p25.3-24.3(chr2:30141-14494040)x3	copy number gain	See cases [RCV000052928]	Chr2:30141..14494040 [GRCh38] Chr2:30141..14634164 [GRCh37] Chr2:20141..14551615 [NCBI36] Chr2:2p25.3-24.3	pathogenic
GRCh38/hg38 2p25.3-23.1(chr2:30141-31766749)x3	copy number gain	See cases [RCV000052929]	Chr2:30141..31766749 [GRCh38] Chr2:30141..31991818 [GRCh37] Chr2:20141..31845322 [NCBI36] Chr2:2p25.3-23.1	pathogenic
GRCh38/hg38 2p25.3-24.3(chr2:30342-14866951)x3	copy number gain	See cases [RCV000052931]	Chr2:30342..14866951 [GRCh38] Chr2:30342..15007075 [GRCh37] Chr2:20342..14924526 [NCBI36] Chr2:2p25.3-24.3	pathogenic
GRCh38/hg38 2p25.3-16.1(chr2:66097-55570637)x3	copy number gain	See cases [RCV000052933]	Chr2:66097..55570637 [GRCh38] Chr2:66097..55797773 [GRCh37] Chr2:56097..55651277 [NCBI36] Chr2:2p25.3-16.1	pathogenic
GRCh38/hg38 2p25.1-24.3(chr2:10216779-13474790)x3	copy number gain	See cases [RCV000052627]	Chr2:10216779..13474790 [GRCh38] Chr2:10356905..13614915 [GRCh37] Chr2:10274356..13532366 [NCBI36] Chr2:2p25.1-24.3	uncertain significance
GRCh38/hg38 2p25.2-24.3(chr2:6531172-16103799)x1	copy number loss	See cases [RCV000053978]	Chr2:6531172..16103799 [GRCh38] Chr2:6671304..16243921 [GRCh37] Chr2:6588755..16161372 [NCBI36] Chr2:2p25.2-24.3	pathogenic

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	1932
Count of miRNA genes:	737
Interacting mature miRNAs:	877
Transcripts:	ENST00000396164, ENST00000417697, ENST00000447433, ENST00000536743, ENST00000544306, ENST00000590207, ENST00000590373
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCh38)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
597527710	GWAS1623784_H	language measurement QTL GWAS1623784 (human)		0.000008	language measurement		2	11122102	11122103	Human
597371404	GWAS1467478_H	HVA measurement, MHPG measurement QTL GWAS1467478 (human)		0.000006	HVA measurement, MHPG measurement		2	11115214	11115215	Human
597362321	GWAS1458395_H	body mass index QTL GWAS1458395 (human)		3e-08	body mass index	body mass index (BMI) (CMO:0000105)	2	11130024	11130025	Human
597372148	GWAS1468222_H	urinary metabolite measurement QTL GWAS1468222 (human)		0.000009	urinary metabolite measurement		2	11117379	11117380	Human

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	entire extraembryonic component	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system
445	1051	890	570	4026	1074	1374	3	304	849	174	1129	2759	2368	18	3179	579	1340	989	136

Sequence

Nucleotide Sequences


RefSeq Transcripts	NR_040080	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC062028	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK090853	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK311163	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC111723	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH471053	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CP068276	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENST00000447433

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	2	11,124,219 - 11,132,770 (-)	Ensembl

Ensembl Acc Id:

ENST00000536743

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	2	11,105,317 - 11,132,176 (-)	Ensembl

Ensembl Acc Id:

ENST00000544306

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	2	11,105,317 - 11,132,221 (-)	Ensembl

Ensembl Acc Id:

ENST00000590207

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	2	11,127,385 - 11,132,255 (-)	Ensembl

Ensembl Acc Id:

ENST00000590373

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	2	11,124,518 - 11,132,821 (-)	Ensembl

Ensembl Acc Id:

ENST00000658220

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	2	11,127,355 - 11,132,088 (-)	Ensembl

Ensembl Acc Id:

ENST00000660479

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	2	11,127,360 - 11,132,784 (-)	Ensembl

Ensembl Acc Id:

ENST00000670240

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	2	11,127,488 - 11,132,168 (-)	Ensembl

Ensembl Acc Id:

ENST00000736634

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	2	11,124,530 - 11,132,787 (-)	Ensembl

Ensembl Acc Id:

ENST00000736635

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	2	11,124,518 - 11,132,721 (-)	Ensembl

Ensembl Acc Id:

ENST00000736636

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	2	11,124,520 - 11,132,260 (-)	Ensembl

Ensembl Acc Id:

ENST00000736637

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	2	11,124,520 - 11,132,254 (-)	Ensembl

Ensembl Acc Id:

ENST00000736638

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	2	11,124,526 - 11,132,260 (-)	Ensembl

Ensembl Acc Id:

ENST00000736639

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	2	11,124,527 - 11,132,260 (-)	Ensembl

Ensembl Acc Id:

ENST00000736640

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	2	11,124,527 - 11,132,253 (-)	Ensembl

Ensembl Acc Id:

ENST00000736641

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	2	11,124,518 - 11,132,229 (-)	Ensembl

Ensembl Acc Id:

ENST00000736642

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	2	11,124,535 - 11,132,217 (-)	Ensembl

Ensembl Acc Id:

ENST00000736643

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	2	11,124,526 - 11,132,199 (-)	Ensembl

Ensembl Acc Id:

ENST00000736644

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	2	11,124,527 - 11,132,193 (-)	Ensembl

Ensembl Acc Id:

ENST00000736645

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	2	11,124,527 - 11,132,192 (-)	Ensembl

Ensembl Acc Id:

ENST00000736646

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	2	11,124,529 - 11,132,143 (-)	Ensembl

Ensembl Acc Id:

ENST00000736647

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	2	11,124,520 - 11,131,941 (-)	Ensembl

Ensembl Acc Id:

ENST00000736648

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	2	11,124,526 - 11,131,871 (-)	Ensembl

Ensembl Acc Id:

ENST00000736649

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	2	11,124,527 - 11,131,855 (-)	Ensembl

Ensembl Acc Id:

ENST00000736650

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	2	11,124,527 - 11,131,853 (-)	Ensembl

Ensembl Acc Id:

ENST00000736651

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	2	11,124,527 - 11,131,852 (-)	Ensembl

Ensembl Acc Id:

ENST00000736652

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	2	11,124,527 - 11,131,646 (-)	Ensembl

Ensembl Acc Id:

ENST00000736653

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	2	11,127,628 - 11,129,962 (-)	Ensembl

Ensembl Acc Id:

ENST00000736654

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	2	11,124,527 - 11,126,479 (-)	Ensembl

RefSeq Acc Id:

NR_040080

RefSeq Status:

VALIDATED

Type:

NON-CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	2	11,099,851 - 11,132,176 (-)	NCBI
GRCh37	2	11,239,977 - 11,272,302 (-)	ENTREZGENE
HuRef	2	11,090,556 - 11,122,135 (-)	ENTREZGENE
CHM1_1	2	11,169,628 - 11,201,912 (-)	NCBI
T2T-CHM13v2.0	2	11,131,309 - 11,164,568 (-)	NCBI

Sequence:

show sequence

GTGCAGACAAAGCCCTGACGAATAGAGGCCTGCGCAGAGTGCCCGGGGTGCAGGGCAGCAGGGC
AGCCAGTGAACCACTGAGCTCGCACTGTAGCCAGTCCTGTGTGCCCCTGCTGGATTCTGCTTCT
ATGAGGGAGGCAGCAAGGAGTTGGGACTTCACAGGGTCTTACTTTGTCGCCCAGGCTGGAGTAC
AGTGGCATGATCGTAGCTCATTGCAGCCTCCACCTCCCTGGGCTCAGGAGATCCATCTCAGCCT
CCTGAGTAGCTGGGACCACAGGTTTTGTTCAGGTTTAGCACAAGCTGTGATGAATATCTTCAAG
CCTCTGCTTCCTGCTGTGGAATTGTTGCCAAAGGACACATTCCCAGATGGGATTACTGAGTCAG
AGGAAGTGGACATTGAGTGGCTCTCAACAGACAGGCTGTGTTGCTCTCACAGTGCCCAGCTTCC
CATGGGTGGCCAGCCGAATGCATTATGGGAGAAAGCAGGTCTCGTGGATAATATTTCTGAAGAT
CGGAGCAGGTTGCCAGGTCCACGTCGGCCATGACTGCAGCACGCTCCGGAGGCAGCAGGGGGCA
CCCTGGAGCTTCGCATCCTCCTTCAGGCCCGCGGCATCTCCCCTGGCTCCACCATCCCCAGGTG
TCTCAGCAGCAGCCTTGTGGCTGTGCCTCTTCTGTGCCCTCCGAGTTCTAGGCTGAGGGTGAGG
ATTGGATGAGTTGATCCACGCAAGGCTCCTGGCACAGTGCCTGGCATATGGTTAAATAGACTTG
AAGTTATAATTACCAGGCCTGTTTCCTCCTCATGAGAGGTGGAGCGGTGGTTCCCAAACACGAT
GTGGGAAGTGTGTTAAAATGCAGATCCTGGGCTCGACCCTGAAGCTCTTCCGGCATCCACCTTC
CCAGGTGACCAGACTCTGGGGAAGGCATCACCTCAAGACTCCTGCACCCTTCCTCCAGAGTCCT
GGGATTCAGCTAAATCCTGGGAAGCTCACTGCTGCCTTGACCTCCTGGGCTCAAGTGATCCTCC
CACCTCAGCCTCCTGGGTAGCTACAACTGCATATGTGCATCATCACGCCTGGGTGCCTGCCTCC
CTGCTGCGCCTGGCCACGTGGAAACCCCTGTAGCTCCCTGGCTGTGCAGGAGCAGCCACAGTGT
GCCCCTCCCAGGACCACCATCCCCCTCACTGTCTCTGAGGCACCTGCGTGGACCGGGTCTGGAT
TGAGTCTCATTTCTCTGGATTCCCACGGCAGCCGGCGGCTGCCTCTCCCACACCCGTCACTCTG
TGTCATGGAAAGCTGTGTGTTTGTCTTCATTCCCACCGAGTCTGAGCCACTCGAGGTCAGGGCC
ATGACCGTGAGCTACACGTCCTTGGCGCCCAGTGTGAGCCGTGTACAGTAGAGGCTGACTGACG
TCTTGGAGGCAGAATCCTGATCCCTGACTGCCATCTGGACTTGGAGGCAGGGTTAGGGAAGATC
CTGCTCCTGGAAGGAGAAAGATGTGGAGTGGAGAAAATCTCAGCCACCAGGAAGACAAATGGGA
GGACGGAGCCTTCCCGCCAGGCAGGTGGTGAGGAAGAGTGGGGTAGAGCCAGGCGGCACAGGCA
GCAGCCCTTGATGTGCCAAGGCTGGAGCGTGAACT

hide sequence

Protein Sequences


GenBank Protein	AAI11724	(Get FASTA)	NCBI Sequence Viewer
	BAC03531	(Get FASTA)	NCBI Sequence Viewer
	EAX00945	(Get FASTA)	NCBI Sequence Viewer
	Q8N2B8	(Get FASTA)	NCBI Sequence Viewer

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q8N2B8-F1-model_v2	AlphaFold	Q8N2B8	1-174	view protein structure

Promoters

RGD ID:

6796938

Promoter ID:

HG_KWN:31519

Type:

Non-CpG

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

CD4+TCell, HeLa_S3

Transcripts:

ENST00000273641, ENST00000381585, ENST00000396164, NM_182500, OTTHUMT00000239267, OTTHUMT00000323581, UC002RAZ.1, UC002RBA.1, UC002RBB.1

Position:

Human Assembly	Chr	Position (strand)	Source
Build 36	2	11,190,281 - 11,190,781 (+)	MPROMDB

Additional Information

External Database Links

Database	Acc Id	Source(s)
COSMIC	FLJ33534	COSMIC
Ensembl Genes	ENSG00000145063	Ensembl, ENTREZGENE
Ensembl Transcript	ENST00000536743	ENTREZGENE
GTEx	ENSG00000145063	GTEx
Human Proteome Map	FLJ33534	Human Proteome Map
NCBI Gene	285150	ENTREZGENE
RNAcentral	URS0000065A06	RNACentral
	URS0000154D4D	RNACentral
	URS00001B28CC	RNACentral
	URS0000306756	RNACentral
	URS0000759C02	RNACentral
	URS0000EEC205	RNACentral
	URS0000EED5DE	RNACentral
	URS0000EEE741	RNACentral
	URS0000EF2EEB	RNACentral
UniProt	Q8N2B8	ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary	Q2NKN5	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2022-05-31	FLJ33534	Putative uncharacterized protein FLJ33534	FLJ33534	uncharacterized LOC285150	Symbol and/or name change	5135510	APPROVED
2011-11-01	FLJ33534	uncharacterized LOC285150	FLJ33534	hypothetical LOC285150	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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