LOC132412642 (STARR-positive B cell enhancer ABC_E8235) - Rat Genome Database

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Gene: LOC132412642 (STARR-positive B cell enhancer ABC_E8235) Mus musculus
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Symbol: LOC132412642
Name: STARR-positive B cell enhancer ABC_E8235
RGD ID: 401837552
Description: This genomic region was identified as a putative B cell regulatory element by FAIRE-seq (formaldehyde-assisted isolation of regulatory elements sequencing), and was validated as an enhancer by STARR-seq (self-transcribing active regulatory region sequencing) in lipopolysaccharide-activated mouse splenic B cells. [provided by RefSeq, Oct 2023]
Type: biological-region
RefSeq Status: REVIEWED
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39867,312,642 - 67,312,943 (+)NCBIGRCm39GRCm39mm39
JBrowse: View Region in Genome Browser (JBrowse)
Model


PMID:31873292   PMID:31873293  



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Variants in LOC132412642
22 total Variants

1 to 10 of 76 rows
Name
Type
Condition(s)
Position(s)
Clinical significance
GRCh38/hg38 19q13.12(chr19:36439647-37163160)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051288]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051288]|See cases [RCV000051288] Chr19:36439647..37163160 [GRCh38]
Chr19:36930549..37654062 [GRCh37]
Chr19:41622389..42345902 [NCBI36]
Chr19:19q13.12		 uncertain significance
NM_001242800.1(ZNF790):c.1542C>T (p.Ala514=) single nucleotide variant Malignant melanoma [RCV000072104] Chr19:36818802 [GRCh38]
Chr19:37309704 [GRCh37]
Chr19:42001544 [NCBI36]
Chr19:19q13.12		 not provided
NM_001242800.1(ZNF790):c.521A>T (p.Glu174Val) single nucleotide variant Malignant melanoma [RCV000072105] Chr19:36819823 [GRCh38]
Chr19:37310725 [GRCh37]
Chr19:42002565 [NCBI36]
Chr19:19q13.12		 not provided
NM_206894.3(ZNF790):c.764A>G (p.Lys255Arg) single nucleotide variant Malignant melanoma [RCV000063521] Chr19:36819580 [GRCh38]
Chr19:37310482 [GRCh37]
Chr19:42002322 [NCBI36]
Chr19:19q13.12		 not provided
GRCh38/hg38 19p13.2-q13.31(chr19:11227942-44626354)x3 copy number gain See cases [RCV000133888] Chr19:11227942..44626354 [GRCh38]
Chr19:11338618..45129651 [GRCh37]
Chr19:11199618..49821491 [NCBI36]
Chr19:19p13.2-q13.31		 pathogenic
GRCh38/hg38 19q12-13.13(chr19:29661858-38114723)x1 copy number loss See cases [RCV000135879] Chr19:29661858..38114723 [GRCh38]
Chr19:30152765..38605363 [GRCh37]
Chr19:34844605..43297203 [NCBI36]
Chr19:19q12-13.13		 pathogenic
GRCh38/hg38 19q12-13.13(chr19:29671324-37902990)x1 copy number loss See cases [RCV000136794] Chr19:29671324..37902990 [GRCh38]
Chr19:30162231..38393630 [GRCh37]
Chr19:34854071..43085470 [NCBI36]
Chr19:19q12-13.13		 pathogenic
GRCh37/hg19 19q13.12-13.2(chr19:36685995-38708166)x1 copy number loss Breast ductal adenocarcinoma [RCV000207200] Chr19:36685995..38708166 [GRCh37]
Chr19:19q13.12-13.2		 uncertain significance
chr19:36674305-38652962 complex variant complex Breast ductal adenocarcinoma [RCV000207036] Chr19:36674305..38652962 [GRCh37]
Chr19:19q13.12-13.13		 uncertain significance
GRCh37/hg19 19q13.12-13.13(chr19:36475577-38399402)x3 copy number gain See cases [RCV000240597] Chr19:36475577..38399402 [GRCh37]
Chr19:19q13.12-13.13		 uncertain significance
1 to 10 of 76 rows

1 to 10 of 30 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1558870Eae36_mexperimental allergic encephalomyelitis susceptibility 36 (mouse)Not determined81477316071498244Mouse
10043992Hbnr11_mHeligmosomoides bakeri nematode resistance 11 (mouse)Not determined866326836100326976Mouse
4141437W10q14_mweight 10 weeks QTL 14 (mouse)Not determined3250657271740637Mouse
1301013Capsq4_mcapsaicin sensitivity related QTL 4 (mouse)Not determined83663015493455280Mouse
1301717Adip4_madiposity 4 (mouse)Not determined84809006482090180Mouse
1357715Alaa3_malopecia areata 3 (mouse)Not determined84924559183245673Mouse
11353828Gf7_mgonadal fat pad weight 7 (mouse)85892810792928107Mouse
14746987Manh64_mmandible shape 64 (mouse)85050595884505958Mouse
4141172W6q9_mweight 6 weeks QTL 9 (mouse)Not determined3250657271740637Mouse
1558875Eae31_mexperimental allergic encephalomyelitis susceptibility 31 (mouse)Not determined835109930115563747Mouse

1 to 10 of 30 rows





RefSeq Transcripts NG_236488 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC116731 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles



Database
Acc Id
Source(s)
NCBI Gene LOC132412642 ENTREZGENE
PhenoGen LOC132412642 PhenoGen