Sfpe2/sbe1 (sonic hedgehog brain enhancer region in intron 2) - Rat Genome Database

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Gene: Sfpe2/sbe1 (sonic hedgehog brain enhancer region in intron 2) Mus musculus
Analyze
Symbol: Sfpe2/sbe1
Name: sonic hedgehog brain enhancer region in intron 2
RGD ID: 39130921
Description: This region contains a bipartite enhancer element, with separate sub-regions that drive expression of a target promoter in the brain and floor plate. This sequence is recognized by a variety of transcriptional regulators, including homeobox protein Arx. This region regulates expression of the sonic hedgehog (Shh) gene. [provided by RefSeq, Sep 2015]
Type: biological-region
RefSeq Status: REVIEWED
Previously known as: Rr366626
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39528,663,813 - 28,665,111 (+)NCBIGRCm39GRCm39mm39
GRCm38528,458,815 - 28,460,113 (+)NCBIGRCm38GRCm38mm10GRCm38
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:9847242   PMID:11023872   PMID:12835403   PMID:15498458   PMID:16407397   PMID:17157288   PMID:21205797   PMID:24968361   PMID:25252942  


Genomics

Variants

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Variants in Sfpe2/sbe1
69 total Variants

QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12904958Gmmq8_mgastrocnemius muscle mass QTL 8 (mouse)5129421124Mouse
10401122Pgia41_mproteoglycan induced arthritis 41 (mouse)Not determined582314434823280Mouse
15039371Nmrs21_mNAFLD-associated magnetic resonance shift 21 (mouse)5350482337504823Mouse
1301806Actd2_mactivity-distance traveled 2 (mouse)Not determined5538452039384652Mouse
4141207Imrfq1_mimmune response to Factor IX QTL 1 (mouse)Not determined5812411742124239Mouse
7394748Mom5_mmodifier of Min 5 (mouse)Not determined5884767233475637Mouse
1301693Sle6_msystemic lupus erythematosus susceptibility 6 (mouse)Not determined5889069387841837Mouse
1357478Kdnw1_mkidney weight 1 (mouse)Not determined5891594940529869Mouse
14696730Kidlq1_mkidney weight, left QTL 1 (mouse)51356315247563152Mouse
1301685Estq2_mestradiol regulated response QTL 2 (mouse)Not determined51563408449634190Mouse
1300719Iba5_minduction of brown adipocytes 5 (mouse)Not determined52068699354687134Mouse
1301776Skts3_mskin tumor susceptibility 3 (mouse)Not determined52166729555667403Mouse
11537368Hmtb10_mhemostasis and thrombosis 10 (mouse)52210082354500318Mouse
11537367Hmtb11_mhemostasis and thrombosis 11 (mouse)52210082364806579Mouse
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526441234138455402Mouse
1300701Cd8ts1_mCD8 T cell subset 1 (mouse)Not determined52721534861215451Mouse


Expression


Sequence



Additional Information

Database Acc Id Source(s)
NCBI Gene Sfpe2/sbe1 ENTREZGENE
PhenoGen Sfpe2/sbe1 PhenoGen