Tas2r110 (taste receptor, type 2, member 110) - Rat Genome Database

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Gene: Tas2r110 (taste receptor, type 2, member 110) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Tas2r110
Name: taste receptor, type 2, member 110
RGD ID: 2314263
Description: Predicted to enable bitter taste receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception of bitter taste. Predicted to be active in membrane. Orthologous to human TAS2R14 (taste 2 receptor member 14).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: T2R10; T2R110; taste receptor type 2 member 10; taste receptor type 2 member 110
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84167,983,779 - 167,984,780 (-)NCBIGRCr8
mRatBN7.24166,252,371 - 166,253,372 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4166,252,371 - 166,253,372 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4172,545,848 - 172,546,849 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04168,328,879 - 168,329,880 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04166,962,913 - 166,963,914 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04167,129,995 - 167,130,996 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4167,129,995 - 167,130,996 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04229,658,691 - 229,659,692 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44170,196,624 - 170,197,625 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera4154,849,036 - 154,850,037 (-)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (IBA,IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. A novel family of mammalian taste receptors. Adler E, etal., Cell 2000 Mar 17;100(6):693-702.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10761935   PMID:11696554   PMID:11854532   PMID:12139982   PMID:12581520  


Genomics

Variants

.
Variants in Tas2r110
17 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:126
Count of miRNA genes:96
Interacting mature miRNAs:103
Transcripts:ENSRNOT00000040860
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
6478754Anxrr43Anxiety related response QTL 430.14035locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4144639524182687754Rat
724558Plsm2Polydactyly-luxate syndrome (PLS) morphotypes QTL 20.0003hindlimb integrity trait (VT:0010563)hind foot phalanges count (CMO:0001949)4132422778177422778Rat
1582237Kidm34Kidney mass QTL 3440.0001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)4148090542168069246Rat
6478693Anxrr32Anxiety related response QTL 320.00092locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4144639524182687754Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)426775591168368347Rat
631683Bp116Blood pressure QTL 1160.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4124303370169303370Rat
61451Ciaa4CIA Autoantibody QTL 43.1blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)4126395976167139601Rat
1331738Bp209Blood pressure QTL 2092.979arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)4138503169179293946Rat
6478700Anxrr33Anxiety related response QTL 330.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
1298524Oia8Oil induced arthritis QTL 8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4138503169173369699Rat
10053718Scort25Serum corticosterone level QTL 252.150.0097blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)4155561574182687754Rat
1549827Scl46Serum cholesterol level QTL 463.5blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)4132396220177396220Rat
737821Hcar9Hepatocarcinoma resistance QTL 93.7liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)4109866907167139601Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)493308457167139447Rat
7411558Bw133Body weight QTL 13313.840.001body mass (VT:0001259)body weight gain (CMO:0000420)4125590636170590636Rat
6478778Anxrr51Anxiety related response QTL 510.25384locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4124778595169778595Rat
10401796Kidm48Kidney mass QTL 48kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)4145568712182687754Rat
6478718Anxrr34Anxiety related response QTL 340.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
631511Pia7Pristane induced arthritis QTL 74.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4131730738167139601Rat
1300109Rf13Renal function QTL 133.91renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)4157710145182687754Rat
634347Hcar8Hepatocarcinoma resistance QTL 85.8liver integrity trait (VT:0010547)liver tumorous lesion area to total liver area ratio (CMO:0001075)4123143783168143783Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)483428419177635233Rat
2303623Vencon2Ventilatory control QTL 23.8respiration trait (VT:0001943)minute ventilation (CMO:0000132)4135204660180204660Rat
1578674Bmd12Bone mineral density QTL 123.8femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)4135699135180699135Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)485379421167139601Rat
61422Cia13Collagen induced arthritis QTL 134.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4132642577167139601Rat
634342Cia24Collagen induced arthritis QTL 244.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4146565735175236377Rat
737978Pia23Pristane induced arthritis QTL 235.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4131730738167139601Rat
61362Oia2Oil induced arthritis QTL 20.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4138503169173369699Rat
2293659Bmd35Bone mineral density QTL 354.50.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)4137755016181392681Rat
1331759Hrtrt13Heart rate QTL 133.54628heart pumping trait (VT:2000009)heart rate (CMO:0000002)4110275411168266883Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
6478748Anxrr42Anxiety related response QTL 420.28008locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
12798525Anxrr57Anxiety related response QTL 573.210.05locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4147278504167139601Rat


Expression

RNA-SEQ Expression

endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
reproductive system
respiratory system
1 1 1 1 1 5 1

Sequence


Ensembl Acc Id: ENSRNOT00000040860   ⟹   ENSRNOP00000047747
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4166,252,371 - 166,253,372 (-)Ensembl
Rnor_6.0 Ensembl4167,129,995 - 167,130,996 (-)Ensembl
RefSeq Acc Id: NM_001166677   ⟹   NP_001160149
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84167,983,779 - 167,984,780 (-)NCBI
mRatBN7.24166,252,371 - 166,253,372 (-)NCBI
Rnor_6.04167,129,995 - 167,130,996 (-)NCBI
Rnor_5.04229,658,691 - 229,659,692 (-)NCBI
RGSC_v3.44170,196,624 - 170,197,625 (-)RGD
Celera4154,849,036 - 154,850,037 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001160149 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAF45305 (Get FASTA)   NCBI Sequence Viewer  
  AAR13341 (Get FASTA)   NCBI Sequence Viewer  
  EDM01671 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000047747.1
GenBank Protein Q9JKE8 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001160149   ⟸   NM_001166677
- UniProtKB: Q67ET8 (UniProtKB/Swiss-Prot),   Q9JKE8 (UniProtKB/Swiss-Prot),   A6IMB8 (UniProtKB/TrEMBL),   G3V9H7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000047747   ⟸   ENSRNOT00000040860

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9JKE8-F1-model_v2 AlphaFold Q9JKE8 1-333 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2314263 AgrOrtholog
BioCyc Gene G2FUF-42687 BioCyc
Ensembl Genes ENSRNOG00000050637 Ensembl
  ENSRNOG00000067588 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000040860.2 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro T2R UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:100310875 UniProtKB/Swiss-Prot
NCBI Gene 100310875 ENTREZGENE
PANTHER TASTE RECEPTOR TYPE 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TASTE RECEPTOR TYPE 2 MEMBER 110 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam TAS2R UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tas2r110 PhenoGen
RatGTEx ENSRNOG00000050637 RatGTEx
  ENSRNOG00000067588 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A6IMB8 ENTREZGENE, UniProtKB/TrEMBL
  G3V9H7 ENTREZGENE, UniProtKB/TrEMBL
  Q67ET8 ENTREZGENE
  Q9JKE8 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q67ET8 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2009-11-11 Tas2r110  taste receptor, type 2, member 110  Tas2r110  taste receptor type 2 member 110  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-11-06 Tas2r110  taste receptor type 2 member 110      Symbol and Name status set to provisional 70820 PROVISIONAL