Gpr50 (G protein-coupled receptor 50) - Rat Genome Database

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Gene: Gpr50 (G protein-coupled receptor 50) Heterocephalus glaber
Analyze
Symbol: Gpr50
Name: G protein-coupled receptor 50
RGD ID: 18936481
Description: ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); melatonin receptor activity (inferred); INVOLVED IN G protein-coupled receptor signaling pathway (inferred); ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); autosomal hemophilia A (ortholog); FOUND IN nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: melatonin-related receptor
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249231,356,282 - 1,360,447 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249231,356,160 - 1,361,717 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Gpr50
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249231,356,282 - 1,360,447 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249231,356,160 - 1,361,717 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
GPR50
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X151,176,584 - 151,182,856 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX151,176,584 - 151,181,465 (+)EnsemblGRCh38hg38GRCh38
GRCh37X150,345,056 - 150,349,937 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X150,095,717 - 150,100,588 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X150,015,692 - 150,020,505NCBI
CeleraX150,593,370 - 150,598,251 (+)NCBICelera
Cytogenetic MapXq28NCBI
HuRefX139,204,459 - 139,209,328 (+)NCBIHuRef
CHM1_1X150,219,098 - 150,223,979 (+)NCBICHM1_1
T2T-CHM13v2.0X149,444,563 - 149,450,834 (+)NCBIT2T-CHM13v2.0
Gpr50
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X70,707,273 - 70,712,863 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX70,707,273 - 70,712,863 (+)EnsemblGRCm39 Ensembl
GRCm38X71,663,667 - 71,669,257 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX71,663,667 - 71,669,257 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X68,916,942 - 68,921,264 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X67,924,323 - 67,928,645 (+)NCBIMGSCv36mm8
CeleraX62,643,933 - 62,648,261 (+)NCBICelera
Cytogenetic MapXA7.3NCBI
cM MapX36.98NCBI
Gpr50
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X154,413,592 - 154,419,236 (+)NCBIGRCr8
mRatBN7.2X149,368,900 - 149,373,486 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX149,368,900 - 149,373,486 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX151,563,088 - 151,567,674 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X155,097,283 - 155,101,869 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X152,638,841 - 152,643,427 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01736,771,578 - 36,776,225 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1736,771,639 - 36,776,225 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01738,076,056 - 38,080,642 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X157,101,726 - 157,106,312NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X157,178,160 - 157,178,517NCBI
Cytogenetic MapXq37NCBI
Gpr50
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554986,707,630 - 6,711,854 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554986,707,630 - 6,711,854 (+)NCBIChiLan1.0ChiLan1.0
GPR50
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X151,272,799 - 151,279,096 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X151,276,404 - 151,282,701 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X140,785,028 - 140,791,325 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X150,743,304 - 150,749,627 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX150,742,959 - 150,749,652 (+)Ensemblpanpan1.1panPan2
GPR50
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X119,266,369 - 119,271,586 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX119,266,480 - 119,271,586 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX104,647,468 - 104,652,539 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X121,486,314 - 121,491,188 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX121,486,314 - 121,491,188 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X118,212,023 - 118,216,889 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X120,689,866 - 120,694,730 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X120,572,470 - 120,577,339 (+)NCBIUU_Cfam_GSD_1.0
Gpr50
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X116,834,675 - 116,840,785 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367141,417,044 - 1,421,782 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367141,417,044 - 1,421,782 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GPR50
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX122,708,427 - 122,714,164 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X122,708,551 - 122,713,163 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X140,336,319 - 140,341,947 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GPR50
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X125,714,733 - 125,721,180 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX125,714,883 - 125,719,762 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606563,474,776 - 63,481,211 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_004874138 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01104711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSHGLT00000000315   ⟹   ENSHGLP00000000281
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046249231,356,282 - 1,360,447 (+)Ensembl
RefSeq Acc Id: XM_004874138   ⟹   XP_004874195
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249231,356,160 - 1,361,717 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004874195 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000000281
RefSeq Acc Id: XP_004874195   ⟸   XM_004874138
- UniProtKB: A0AAX6QFB6 (UniProtKB/TrEMBL),   G5BRR5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000000281   ⟸   ENSHGLT00000000315


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000000278 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000000315 ENTREZGENE
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Mel_rcpt_1X UniProtKB/TrEMBL
  Melatonin_rcpt UniProtKB/TrEMBL
NCBI Gene Gpr50 ENTREZGENE
PANTHER B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR UniProtKB/TrEMBL
  MELATONIN-RELATED RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/TrEMBL
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  MELATONIN1XR UniProtKB/TrEMBL
  MELATONINR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
SMART 7TM_GPCR_Srsx UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0AAX6QFB6 ENTREZGENE, UniProtKB/TrEMBL
  G5BRR5 ENTREZGENE, UniProtKB/TrEMBL