Nrl (neural retina leucine zipper) - Rat Genome Database

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Gene: Nrl (neural retina leucine zipper) Heterocephalus glaber
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Symbol: Nrl
Name: neural retina leucine zipper
RGD ID: 18934449
Description: ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); DNA-binding transcription factor activity (inferred); INVOLVED IN positive regulation of gene expression (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH Brain-Lung-Thyroid Syndrome (ortholog); enhanced S-cone syndrome (ortholog); Foveal Hypoplasia (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Neural retina-specific leucine zipper protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248208,444,687 - 8,449,354 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248208,436,469 - 8,449,354 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
cytosol  (IEA)
nucleoplasm  (IEA)
nucleus  (IEA)

References
Additional References at PubMed
PMID:21993625   PMID:30032202  


Genomics

Comparative Map Data
Nrl
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248208,444,687 - 8,449,354 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248208,436,469 - 8,449,354 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
NRL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381424,078,662 - 24,114,949 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1424,078,662 - 24,115,010 (-)EnsemblGRCh38hg38GRCh38
GRCh371424,547,871 - 24,584,158 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361423,619,156 - 23,623,672 (-)NCBINCBI36Build 36hg18NCBI36
Build 341423,619,215 - 23,654,063NCBI
Celera144,413,793 - 4,418,309 (-)NCBICelera
Cytogenetic Map14q11.2-q12NCBI
HuRef144,664,249 - 4,668,765 (-)NCBIHuRef
CHM1_11424,547,991 - 24,552,507 (-)NCBICHM1_1
T2T-CHM13v2.01418,276,978 - 18,313,262 (-)NCBIT2T-CHM13v2.0
Nrl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391455,756,973 - 55,762,438 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1455,756,435 - 55,762,438 (-)EnsemblGRCm39 Ensembl
GRCm381455,518,978 - 55,524,981 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1455,518,978 - 55,524,981 (-)EnsemblGRCm38mm10GRCm38
MGSCv371456,137,815 - 56,143,802 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361454,473,049 - 54,478,262 (-)NCBIMGSCv36mm8
Celera1453,323,817 - 53,329,813 (-)NCBICelera
Cytogenetic Map14C3NCBI
cM Map1428.19NCBI
Nrl
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81532,977,023 - 32,981,442 (-)NCBIGRCr8
mRatBN7.21529,007,059 - 29,011,480 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1529,008,104 - 29,009,832 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1530,853,805 - 30,855,533 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01532,001,015 - 32,002,743 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01530,243,363 - 30,245,091 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01534,197,115 - 34,201,408 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1534,197,193 - 34,198,921 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01538,087,364 - 38,108,942 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41533,649,927 - 33,656,045 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11533,667,545 - 33,669,274 (-)NCBI
Celera1528,584,069 - 28,585,797 (-)NCBICelera
Cytogenetic Map15p13NCBI
Nrl
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540936,310,932 - 36,313,893 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540936,279,996 - 36,313,824 (+)NCBIChiLan1.0ChiLan1.0
NRL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21525,436,209 - 25,469,236 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11424,652,701 - 24,685,728 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0144,858,105 - 4,891,207 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11422,982,367 - 23,015,912 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1422,982,367 - 22,998,187 (-)Ensemblpanpan1.1panPan2
NRL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.184,086,487 - 4,090,373 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl84,086,508 - 4,089,216 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha84,009,349 - 4,011,899 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.084,198,235 - 4,200,786 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl84,197,290 - 4,199,944 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.183,888,893 - 3,891,443 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.083,950,633 - 3,953,183 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.084,212,744 - 4,215,293 (-)NCBIUU_Cfam_GSD_1.0
Nrl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864035,934,928 - 35,966,368 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936722447,967 - 454,553 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936722448,006 - 454,064 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NRL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl775,206,719 - 75,210,529 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1775,199,048 - 75,211,655 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2780,470,343 - 80,482,968 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NRL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1241,064,266 - 1,100,995 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl241,064,664 - 1,066,278 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603612,744,482 - 12,758,698 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000005470   ⟹   ENSHGLP00000005400
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248208,444,687 - 8,449,354 (+)Ensembl
RefSeq Acc Id: XM_004864136   ⟹   XP_004864193
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248208,436,469 - 8,449,354 (+)NCBI
RefSeq Acc Id: XM_004864138   ⟹   XP_004864195
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248208,436,469 - 8,449,354 (+)NCBI
RefSeq Acc Id: XM_021243843   ⟹   XP_021099502
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248208,446,854 - 8,449,354 (+)NCBI
RefSeq Acc Id: XM_021243844   ⟹   XP_021099503
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248208,436,469 - 8,449,354 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004864193 (Get FASTA)   NCBI Sequence Viewer  
  XP_004864195 (Get FASTA)   NCBI Sequence Viewer  
  XP_021099502 (Get FASTA)   NCBI Sequence Viewer  
  XP_021099503 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB03411 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000005400
RefSeq Acc Id: XP_004864193   ⟸   XM_004864136
- Peptide Label: isoform X1
- UniProtKB: G5B2A1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021099503   ⟸   XM_021243844
- Peptide Label: isoform X2
- UniProtKB: A0AAX6RT61 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004864195   ⟸   XM_004864138
- Peptide Label: isoform X1
- UniProtKB: G5B2A1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021099502   ⟸   XM_021243843
- Peptide Label: isoform X1
- UniProtKB: G5B2A1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000005400   ⟸   ENSHGLT00000005470


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000003953 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000005470 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.170 UniProtKB/TrEMBL
InterPro bZIP UniProtKB/TrEMBL
  bZIP_Maf UniProtKB/TrEMBL
  bZIP_sf UniProtKB/TrEMBL
  Maf_TF_N UniProtKB/TrEMBL
  TF_DNA-bd_sf UniProtKB/TrEMBL
  Transcription_factor_Maf_fam UniProtKB/TrEMBL
KEGG Report hgl:101705497 UniProtKB/TrEMBL
NCBI Gene Nrl ENTREZGENE
PANTHER PTHR10129 UniProtKB/TrEMBL
  PTHR10129:SF24 UniProtKB/TrEMBL
Pfam bZIP_Maf UniProtKB/TrEMBL
  Maf_N UniProtKB/TrEMBL
PROSITE BZIP UniProtKB/TrEMBL
SMART BRLZ UniProtKB/TrEMBL
Superfamily-SCOP SSF47454 UniProtKB/TrEMBL
  SSF57959 UniProtKB/TrEMBL
UniProt A0AAX6RT61 ENTREZGENE, UniProtKB/TrEMBL
  G5B2A1 ENTREZGENE, UniProtKB/TrEMBL